guanethidine has been researched along with Autotomy Human in 5 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with guanethidine diminished heat and cold sensitization considerably, but had less effect on mechanical sensitization and, if administered before surgery, rather increased the severity of self-mutilating behaviour." | 1.28 | Effects of guanethidine on sensitization to natural stimuli and self-mutilating behaviour in rats with a peripheral neuropathy. ( Attal, N; Guilbaud, G; Neil, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coderre, TJ | 3 |
| Abbott, FV | 1 |
| Melzack, R | 3 |
| Colado, MI | 1 |
| Del Rio, J | 1 |
| Peralta, E | 1 |
| Neil, A | 1 |
| Attal, N | 1 |
| Guilbaud, G | 1 |
| Grimes, RW | 1 |
1 review available for guanethidine and Autotomy Human
| Article | Year |
|---|---|
Deafferentation and chronic pain in animals: an evaluation of evidence suggesting autotomy is related to pain.
Topics: Afferent Pathways; Animals; Behavior, Animal; Capsaicin; Chronic Disease; Denervation; Disease Model | 1986 |
4 other studies available for guanethidine and Autotomy Human
| Article | Year |
|---|---|
Effects of peripheral antisympathetic treatments in the tail-flick, formalin and autotomy tests.
Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Formaldehyde; Guanethidine; Hot Tempe | 1984 |
Neonatal guanethidine sympathectomy suppresses autotomy and prevents changes in spinal and supraspinal monoamine levels induced by peripheral deafferentation in rats.
Topics: Animals; Animals, Newborn; Biogenic Monoamines; Denervation; Guanethidine; Hydroxyindoleacetic Acid; | 1994 |
Effects of guanethidine on sensitization to natural stimuli and self-mutilating behaviour in rats with a peripheral neuropathy.
Topics: Animals; Cold Temperature; Guanethidine; Hot Temperature; Male; Peripheral Nervous System Diseases; | 1991 |
Cutaneous hyperalgesia: contributions of the peripheral and central nervous systems to the increase in pain sensitivity after injury.
Topics: Animals; Burns; Capsaicin; Central Nervous System; Guanethidine; Hyperalgesia; Hyperesthesia; Male; | 1987 |