guanethidine has been researched along with Arthritis, Rheumatoid in 4 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A novel therapy for rheumatoid arthritis, regional sympathetic blockade using guanethidine, was investigated in 24 patients with active disease." | 9.06 | Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis. ( Basbaum, AI; Fye, K; Heller, P; Levine, JD; Whiting-O'Keefe, Q, 1986) |
| "A novel therapy for rheumatoid arthritis, regional sympathetic blockade using guanethidine, was investigated in 24 patients with active disease." | 5.06 | Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis. ( Basbaum, AI; Fye, K; Heller, P; Levine, JD; Whiting-O'Keefe, Q, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blunt, RJ | 1 |
| Porter, JM | 1 |
| Hannington-Kiff, JG | 1 |
| Levine, JD | 1 |
| Fye, K | 1 |
| Heller, P | 1 |
| Basbaum, AI | 1 |
| Whiting-O'Keefe, Q | 1 |
| Caprino, L | 1 |
| Borrelli, F | 1 |
| Falchetti, R | 1 |
1 review available for guanethidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Raynaud syndrome.
Topics: Adrenergic beta-Antagonists; Adult; Angiography; Antibodies, Antinuclear; Arterial Occlusive Disease | 1981 |
1 trial available for guanethidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autonomic Nerve Block; Clinical Trials as Topic; Co | 1986 |
2 other studies available for guanethidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Rheumatoid arthritis-interventional treatment with regionally applied drugs and the use of sympathetic modulation: discussion paper.
Topics: Administration, Cutaneous; Analgesics; Animals; Arthritis, Rheumatoid; Aspirin; Female; Guanethidine | 1990 |
Pharmacological research on 4,5-diphenyl-2-bis(2-hydroxyethyl)-aminoxazol (Ditazol), a new synthetic oxazole derivative as an anti-inflammatory agent.
Topics: Administration, Oral; Administration, Topical; Adrenalectomy; Analgesics; Animals; Anti-Inflammatory | 1973 |