guanethidine has been researched along with Aortic Coarctation in 4 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Guanethidine treatment did not affect the arterial pressure or heart rate responses to aortic coarctation of intact rats but blunted the hypertensive response of SAD rats to the same values exhibited by intact rats." | 1.30 | Influence of sympathetic blockade on the acute hypertensive response to aortic constriction. ( Ballejo, G; Castania, JA; Fazan Júnior, R; Salgado, HC; Salgado, MC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TUCKMAN, J | 1 |
| SHILLINGFORD, J | 1 |
| Fazan Júnior, R | 1 |
| Castania, JA | 1 |
| Ballejo, G | 1 |
| Salgado, MC | 1 |
| Salgado, HC | 1 |
| Jeresaty, RM | 1 |
| Basu, SK | 1 |
| Franco, J | 1 |
| O'Gorman, LP | 1 |
| Wilson, AM | 1 |
| Castillo-Olivares, J | 1 |
4 other studies available for guanethidine and Aortic Coarctation
| Article | Year |
|---|---|
THE HAEMODYNAMIC EFFECTS OF SODIUM AMOBARBITAL IN HYPERTENSION.
Topics: Amobarbital; Aortic Coarctation; Cardiac Catheterization; Chlorothiazide; Digitalis Glycosides; Guan | 1964 |
Influence of sympathetic blockade on the acute hypertensive response to aortic constriction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Abdominal; Aortic Coarctation; Blood Pressu | 1997 |
Dissecting aneurysm of the aorta in Turner's syndrome.
Topics: Aorta, Abdominal; Aortic Aneurysm; Aortic Coarctation; Aortography; Female; Guanethidine; Humans; Hy | 1972 |
Abnormal levels of catecholamine metabolites in a resected coarctation of the aorta.
Topics: Adult; Aortic Coarctation; Catecholamines; Female; Guanethidine; Humans; Hypertension; Male; Middle | 1969 |