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guanethidine and Anesthesia

guanethidine has been researched along with Anesthesia in 30 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" administration of guanethidine provokes severe and sustained ventricular arrhythmias in cats anesthetized with halothane."7.66Cardiac arrhythmias induced by guanethidine in cats anesthetized with halothane. ( Condouris, GA; Kopia, GA, 1980)
" The effect of systemic administration of ruthenium red on bronchospasm induced by acetylcholine, capsaicin or selective tachykinin receptor agonists ([Sar9]SP sulfone or [beta Ala8]-neurokinin A (NKA)-(4-10) for NK-1 and NK-2 receptors, respectively) was studied in anaesthetized guinea-pigs."3.68Effect of ruthenium red on the bronchoconstriction induced by capsaicin and by selective tachykinin receptor agonists in anaesthetized guinea-pig. ( Ballati, L; Evangelista, S; Maggi, CA, 1992)
" administration of guanethidine provokes severe and sustained ventricular arrhythmias in cats anesthetized with halothane."3.66Cardiac arrhythmias induced by guanethidine in cats anesthetized with halothane. ( Condouris, GA; Kopia, GA, 1980)
"Guanethidine pretreatment (67 mumol kg-1) revealed a facilitatory effect of low doses of the two tachykinins (about 1 nmol kg-1) on gastrointestinal propulsion."1.27Stimulation and inhibition of gastrointestinal propulsion induced by substance P and substance K in the rat. ( Holzer, P, 1985)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199025 (83.33)18.7374
1990's4 (13.33)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOLLOWAY, KB1
HOLMES, F1
HIDER, CF1
HUKOVIC, S1
MUSCHOLL, E1
HUEGIN, W1
CLARK, RB1
MAIER, ES1
HILTON, JG1
ARELLANO, PT1
FENNER, PA1
LEE, PK1
ISRAEL, JS1
DOBKIN, AB1
BALMER, VG1
Tsoucaris-Kupfer, D1
Liblau, L1
Legrand, M1
Schmitt, H1
Condouris, GA1
Kopia, GA1
Beattie, DT1
Connor, HE1
Raval, P2
Bingham, S2
Aiyar, N1
Elliott, JD1
Hunter, AJ1
Ohlstein, EH1
Parsons, AA2
Read, S1
Thompson, M1
Upton, N1
Johnson, BM1
Chu, D1
Hofmann, A1
Stürmer, E1
Nolan, PL1
Bentley, GA1
Ozawa, H1
Chen, CS1
Watanabe, H1
Uematsu, T1
Almeida, HO1
Cosnier, D1
Duchene-Marullaz, P1
Grimal, J1
Rispat, G1
Streichenberger, G1
Ballati, L1
Maggi, CA1
Evangelista, S1
Tallarida, G1
Iellamo, F1
Raimondi, G1
Legramante, JM1
Cassarino, S1
Marazza, D1
Di Nardo, P1
Peruzzi, G1
Holzer, P2
Donnerer, J1
Schuligoi, R1
Lembeck, F1
Antonaccio, MJ1
Brunner, H1
Hedwall, P1
Maître, L1
Meier, M1
Mocavero, G1
Nagaoka, A1
Kikuchi, K1
Aramaki, Y1
Kobinger, W1
Oda, M1
Arens, JF1
Schulte-Steinberg, O1

Reviews

3 reviews available for guanethidine and Anesthesia

ArticleYear
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
    Der Anaesthesist, 1963, Volume: 12

    Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C

1963
ANTIHYPERTENSIVE DRUGS AND GENERAL ANAESTHESIA.
    The Medical journal of Australia, 1965, Jan-30, Volume: 1, Issue:5

    Topics: Anesthesia; Anesthesia, General; Antihypertensive Agents; Bretylium Compounds; Carbamates; Diuretics

1965
[Factors influencing hemodynamics during anesthesia].
    Minerva anestesiologica, 1968, Volume: 34, Issue:1

    Topics: Adrenal Cortex Hormones; Anesthesia; Carbon Dioxide; Catecholamines; Guanethidine; Hemodynamics; Hum

1968

Other Studies

27 other studies available for guanethidine and Anesthesia

ArticleYear
Guanethidine in hypotensive anaesthesia; clinical study in patients undergoing microsurgery of the middle ear.
    British journal of anaesthesia, 1961, Volume: 33

    Topics: Amidines; Anesthesia; Anesthesiology; Antihypertensive Agents; Ear, Middle; Guanethidine; Hypotensio

1961
[Noradrenalin loss from the isolated rabbit heart following sympathetic nerve irritation and its pharmacological alteration].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1962, Volume: 244

    Topics: Anesthesia; Anesthesia, Local; Animals; Autonomic Nervous System; Calcium; Cocaine; Ganglia; Ganglia

1962
EFFECTS OF PREVIOUS AND CONCOMITANT DRUG THERAPY ON SURGERY AND ANESTHESIA.
    GP, 1964, Volume: 29

    Topics: Adrenal Cortex Hormones; Anesthesia; Anti-Bacterial Agents; Antihypertensive Agents; Bretylium Compo

1964
EFFECTS OF ALTERATION OF SYMPATHETIC TONE UPON THE BLOOD PRESSURE RESPONSE TO EPINEPHRINE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 143

    Topics: Adrenalectomy; Anesthesia; Anesthesia, Spinal; Animals; Anti-Arrhythmia Agents; Blood Pressure; Bret

1964
THE EFFECT OF EPINEPHRINE ON ANAESTHETIZED HYPERTHYROID DOGS PRETREATED WITH RESERPINE AND/OR GUANETHIDINE.
    Canadian Anaesthetists' Society journal, 1964, Volume: 11

    Topics: Anesthesia; Anesthesiology; Dogs; Epinephrine; Guanethidine; Hyperthyroidism; Methoxyflurane; Pharma

1964
Central cardiovascular action of penicillin in anaesthetized dogs and rats.
    Neuropharmacology, 1983, Volume: 22, Issue:7

    Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Clonidine; Dogs; Female; gamma-Aminobutyric Acid

1983
Cardiac arrhythmias induced by guanethidine in cats anesthetized with halothane.
    European journal of pharmacology, 1980, Dec-05, Volume: 68, Issue:3

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Body Temperature Regu

1980
The influence of the trigeminal ganglion on carotid blood flow in anaesthetized guinea-pigs.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Carotid Arteries; Electric Stimulation; Guanethidine; Guinea Pi

1994
Trigeminal nerve ganglion stimulation-induced neurovascular reflexes in the anaesthetized cat: role of endothelin(B) receptors in carotid vasodilatation.
    British journal of pharmacology, 1999, Volume: 126, Issue:2

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-R

1999
Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Anesthesia; Animals; Anticonvulsants; Benzamides; Benzopyrans; Cats; Dose-Response Relationship, Dru

2001
The use of radioactive microspheres to compare the effects of hydralazine, guanethidine and SK & F 24260 on the redistribution of cardiac output in anaesthetized rabbits.
    British journal of pharmacology, 1975, Volume: 55, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Dihydropyridines; Guanethidine; Heart Rate; Hyd

1975
Anaesthetised normotensive rats for the detection of hypotensive activity of a beta-adrenoceptor antagonist and other antihypertensive agents.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:11

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Barbiturates; Chloralose;

1978
Studies on orthostatic cardiovascular responses in anaesthetized cats.
    Clinical and experimental pharmacology & physiology, 1975, Volume: Suppl 2

    Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Bretylium Compounds; Cats; Clonidine; Guanethidine;

1975
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:1

    Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipram

1977
Mechanism of the acute pulmonary edema induced by intracerebroventricular injection of scorpion toxin (tityustoxin) in the unanesthetized rat.
    Toxicon : official journal of the International Society on Toxinology, 1976, Volume: 14, Issue:6

    Topics: Adrenalectomy; Anesthesia; Animals; Antivenins; Guanethidine; Hexamethonium Compounds; Injections, I

1976
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Dogs; Dose-Response R

1975
Effect of ruthenium red on the bronchoconstriction induced by capsaicin and by selective tachykinin receptor agonists in anaesthetized guinea-pig.
    Journal of autonomic pharmacology, 1992, Volume: 12, Issue:5

    Topics: Anesthesia; Animals; Bronchial Spasm; Bronchoconstriction; Capsaicin; Guanethidine; Guinea Pigs; Mal

1992
On the role of neural mechanisms in the cardiocirculatory inhibitory action of alpha-human atrial natriuretic peptide in the anesthetized rabbit.
    Journal of hypertension, 1991, Volume: 9, Issue:10

    Topics: Anesthesia; Animals; Atrial Natriuretic Factor; Atropine; Autonomic Nervous System; Blood Pressure;

1991
Stimulation and inhibition of gastrointestinal propulsion induced by substance P and substance K in the rat.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: Anesthesia; Animals; Atropine; Blood Pressure; Gastrointestinal Motility; Guanethidine; Nerve Tissue

1985
Influence of capsaicin-induced denervation on neurogenic and humoral control of arterial pressure.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:6 Pt 2

    Topics: Anesthesia; Animals; Blood Pressure; Capsaicin; Denervation; Female; Guanethidine; Neurons, Afferent

1989
Capsaicin-sensitive afferent neurones and gastrointestinal propulsion in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:1

    Topics: Anesthesia; Animals; Capsaicin; Defecation; Eating; Female; Gastric Emptying; Gastrointestinal Motil

1986
Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chl

1974
[Modification of the eserine pressor effect by propranolol].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 254, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Brain; Drug Synergism; Female; Guanethidine; Male; Myocardium;

1966
Depressor responses of the spontaneously hypertensive rats to the anti-hypertensive agents.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Guanethidine; He

1969
Effects of sympathetic blocking substances on the diving reflex of ducks.
    European journal of pharmacology, 1969, Volume: 7, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Bretylium Compounds; Diving; Ducks; Guanethidine; Heart Rate; I

1969
The effect of various drugs upon the course of anesthesia.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1970, Volume: 122, Issue:12

    Topics: Adrenal Cortex Hormones; Anesthesia; Anesthetics; Chlorothiazide; Guanethidine; Humans; Methyldopa;

1970
["Nil nocere" in drug pretreatment of surgical patients].
    Munchener medizinische Wochenschrift (1950), 1967, Nov-03, Volume: 109, Issue:44

    Topics: Acetazolamide; Adrenal Cortex Hormones; Anesthesia; Anti-Bacterial Agents; Anticoagulants; Antihyper

1967