guanethidine has been researched along with Alloxan Diabetes in 9 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chemical sympathectomy induced by guanethidine (100 mg/kg body weight, for 1 or 2 days) reduced muscle norepinephrine content to negligible levels (less than 5%), decreased plasma epinephrine concentration, and further increased the high rate of protein degradation in muscles from acutely diabetic rats." | 3.74 | Chemical sympathectomy further increases muscle protein degradation of acutely diabetic rats. ( Baviera, AM; Kettelhut, IC; Migliorini, RH; Navegantes, LC; Zanon, NM, 2008) |
| "Guanethidine pretreatment did not block the ability of centrally administered leptin to decrease blood glucose concentrations in diabetic rats." | 1.35 | Guanethidine treatment does not block the ability of central leptin administration to decrease blood glucose concentrations in streptozotocin-induced diabetic rats. ( Huggins, KW; Judd, RL; Wang, J; Wernette, CM; White, BD, 2008) |
| "The effect of streptozotocin diabetes of 4-week duration on the adrenergic motor transmission and on the nonadrenergic, noncholinergic, inhibitory transmission in the rat anococcygeus was investigated by recording contractile and relaxant activity of isolated muscle preparations taken from diabetic and age-matched control animals." | 1.28 | Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus. ( Luheshi, GN; Zar, MA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Wernette, CM | 1 |
| Judd, RL | 1 |
| Huggins, KW | 1 |
| White, BD | 1 |
| Baviera, AM | 1 |
| Zanon, NM | 1 |
| Navegantes, LC | 1 |
| Migliorini, RH | 1 |
| Kettelhut, IC | 1 |
| Nangle, MR | 1 |
| Cotter, MA | 2 |
| Cameron, NE | 2 |
| Schmidt, RE | 1 |
| Geller, DM | 1 |
| Johnson, EM | 1 |
| Cheng, JT | 1 |
| Liu, IM | 1 |
| Chi, TC | 1 |
| Tzeng, TF | 1 |
| Luheshi, GN | 1 |
| Zar, MA | 1 |
| Zochodne, DW | 1 |
| Ho, LT | 1 |
| Juul, P | 1 |
| Christensen, HB | 1 |
| Hougen, HP | 1 |
| Svendsen, O | 1 |
| Thygesen, P | 1 |
| Rygaard, J | 1 |
| Low, PA | 1 |
1 review available for guanethidine and Alloxan Diabetes
| Article | Year |
|---|---|
Athymic experimental animals in pharmaco-immunological research.
Topics: Animals; Diabetes Mellitus, Experimental; Guanethidine; Killer Cells, Natural; Mice; Mice, Nude; Rat | 1992 |
8 other studies available for guanethidine and Alloxan Diabetes
| Article | Year |
|---|---|
Guanethidine treatment does not block the ability of central leptin administration to decrease blood glucose concentrations in streptozotocin-induced diabetic rats.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Adrenergic Agents; Animals; Blood Glucose; Body Weight | 2008 |
Chemical sympathectomy further increases muscle protein degradation of acutely diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus, Experimental; Disease Models, Anima | 2008 |
IkappaB kinase 2 inhibition corrects defective nitrergic erectile mechanisms in diabetic mouse corpus cavernosum.
Topics: Animals; Atropine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimu | 2006 |
Characterization of increased plasma dopamine-beta-hydroxylase activity in rats with experimental diabetes.
Topics: Adrenal Gland Neoplasms; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dopamine beta-Hydr | 1981 |
Release of beta-endorphin by prostaglandin E2 to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellit | 2001 |
Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus.
Topics: Aldehyde Reductase; Animals; Autonomic Nervous System Diseases; Diabetes Mellitus, Experimental; Dia | 1992 |
The influence of indomethacin and guanethidine on experimental streptozotocin diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Guanethidine; Indomethacin; Male; N | 1992 |
Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Glycosylation; | 1991 |