guanethidine has been researched along with Allodynia in 9 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sympathectomy using guanethidine significantly alleviated mechanical allodynia 6 weeks after cuff, when peak sympathetic sprouting was observed, having no effect at 2 weeks, when fibres were absent." | 3.81 | Sympathetic fibre sprouting in the skin contributes to pain-related behaviour in spared nerve injury and cuff models of neuropathic pain. ( Magnussen, C; Nascimento, FP; Ribeiro-da-Silva, A; Yousefpour, N, 2015) |
| "Although chronic pain is the most common symptom of arthritis, relatively little is known about the mechanisms driving it." | 1.39 | Sympathetic fiber sprouting in inflamed joints and adjacent skin contributes to pain-related behavior in arthritis. ( Longo, G; Osikowicz, M; Ribeiro-da-Silva, A, 2013) |
| "The guanethidine pretreatment did not influence thermal hyperalgesia induced by a mild burn, but inhibited pain evoked by electrical stimulation of the skin (0." | 1.35 | Depletion of noradrenaline inhibits electrically-evoked pain in the skin of the human forearm. ( Drummond, PD, 2008) |
| "Modulation of ultraviolet-induced hyperalgesia and cytokine upregulation by interleukins 10 and 13." | 1.35 | Ultra violet-induced localized inflammatory hyperalgesia in awake rats and the role of sensory and sympathetic innervation of the skin. ( Farhat, O; Jabbur, SJ; Le Bars, D; Rahal, O; Saadé, NE; Safieh-Garabedian, B, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Longo, G | 1 |
| Osikowicz, M | 1 |
| Ribeiro-da-Silva, A | 2 |
| Nascimento, FP | 1 |
| Magnussen, C | 1 |
| Yousefpour, N | 1 |
| Chen, HS | 1 |
| Qu, F | 1 |
| He, X | 1 |
| Wang, Y | 1 |
| Wen, WW | 1 |
| Drummond, PD | 1 |
| Cunha, TM | 1 |
| Verri, WA | 1 |
| Fukada, SY | 1 |
| Guerrero, AT | 1 |
| Santodomingo-Garzón, T | 1 |
| Poole, S | 1 |
| Parada, CA | 1 |
| Ferreira, SH | 2 |
| Cunha, FQ | 1 |
| Saadé, NE | 1 |
| Farhat, O | 1 |
| Rahal, O | 1 |
| Safieh-Garabedian, B | 1 |
| Le Bars, D | 1 |
| Jabbur, SJ | 1 |
| Breivik, H | 1 |
| Nakamura, M | 1 |
| Coderre, TJ | 1 |
| Melzack, R | 1 |
9 other studies available for guanethidine and Allodynia
| Article | Year |
|---|---|
Sympathetic fiber sprouting in inflamed joints and adjacent skin contributes to pain-related behavior in arthritis.
Topics: Adrenergic Fibers; Analysis of Variance; Animals; Ankle Joint; Arthritis; Calcitonin Gene-Related Pe | 2013 |
Sympathetic fibre sprouting in the skin contributes to pain-related behaviour in spared nerve injury and cuff models of neuropathic pain.
Topics: Adrenergic Fibers; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Cold Temperature; Der | 2015 |
Chemical or surgical sympathectomy prevents mechanical hyperalgesia induced by intraplantar injection of bee venom in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals | 2010 |
Depletion of noradrenaline inhibits electrically-evoked pain in the skin of the human forearm.
Topics: Adult; Drug Administration Schedule; Electric Stimulation; Forearm; Guanethidine; Humans; Hyperalges | 2008 |
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor.
Topics: Animals; Antibodies; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagoni | 2007 |
Ultra violet-induced localized inflammatory hyperalgesia in awake rats and the role of sensory and sympathetic innervation of the skin.
Topics: Animals; Cytokines; Dermatitis; Disease Models, Animal; Guanethidine; Hyperalgesia; Nerve Growth Fac | 2008 |
Chronic pain and the sympathetic nervous system.
Topics: Autonomic Nervous System Diseases; Causalgia; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1997 |
A peripheral sympathetic component in inflammatory hyperalgesia.
Topics: Adrenergic beta-Antagonists; Animals; Carrageenan; Cocaine; Dinoprostone; Guanethidine; Hyperalgesia | 1987 |
Cutaneous hyperalgesia: contributions of the peripheral and central nervous systems to the increase in pain sensitivity after injury.
Topics: Animals; Burns; Capsaicin; Central Nervous System; Guanethidine; Hyperalgesia; Hyperesthesia; Male; | 1987 |