Page last updated: 2024-10-28

guanethidine and Age-Related Osteoporosis

guanethidine has been researched along with Age-Related Osteoporosis in 3 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Research Excerpts

ExcerptRelevanceReference
"Thirty-six adult male SD rats were randomly divided into the following four groups: sham surgery (Sham) group, guanethidine (GD) group, abdominal transverse aorta coarctation-induced heart failure + normal saline (TAC) group, and TAC + guanethidine (TAC + GD) group."4.31Bone mass loss in chronic heart failure is associated with sympathetic nerve activation. ( Fan, D; Guan, Z; Huang, J; Jia, J; Leng, H; Li, Z; Song, C; Xu, Y; Yuan, W; Zhang, C; Zhang, W; Zhu, J, 2023)
"Osteoporosis is one of the major health problems in our modern world."1.33Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. ( Denhardt, DT; Ezura, Y; Karsenty, G; Kondo, H; Nakashima, K; Nifuji, A; Noda, M; Rittling, SR; Takeda, S, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Guan, Z1
Yuan, W1
Jia, J1
Zhang, C1
Zhu, J1
Huang, J1
Zhang, W1
Fan, D1
Leng, H1
Li, Z1
Xu, Y1
Song, C1
Kondo, H1
Nifuji, A1
Takeda, S1
Ezura, Y1
Rittling, SR1
Denhardt, DT1
Nakashima, K1
Karsenty, G1
Noda, M1
Procacci, P1
Zoppi, M1
Maresca, M1

Other Studies

3 other studies available for guanethidine and Age-Related Osteoporosis

ArticleYear
Bone mass loss in chronic heart failure is associated with sympathetic nerve activation.
    Bone, 2023, Volume: 166

    Topics: Animals; Guanethidine; Heart Failure; Male; Osteoporosis; Osteoprotegerin; RANK Ligand; Rats; Rats,

2023
Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system.
    The Journal of biological chemistry, 2005, Aug-26, Volume: 280, Issue:34

    Topics: Amino Acids; Animals; Biomarkers; Body Weight; Bone and Bones; Bone Marrow Cells; Dopamine beta-Hydr

2005
[Guanethidine therapy of reflex sympathetic syndromes].
    La Clinica terapeutica, 1975, Jun-30, Volume: 73, Issue:6

    Topics: Adult; Aged; Arterial Occlusive Diseases; Causalgia; Drug Evaluation; Edema; Female; Fibromyalgia; G

1975