Compounds > guanabenz

guanabenz and Nerve Degeneration

guanabenz has been researched along with Nerve Degeneration in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fardghassemi, Y; Gosselin, S; Parker, JA; Tauffenberger, A1
Feng, HL; Jiang, HQ; Jiang, HZ; Qi, Y; Ren, M; Wang, J; Wang, SY; Wang, XD; Yin, X; Zhang, J1
De Zutter, GS; Gill, A; Hatzipetros, T; Jiang, B; Kidd, JD; Levine, B; Lincecum, JM; Moreno, AJ; Perrin, S; Ping, Q; Tassinari, VR; Thompson, K; Vieira, FG; Wang, MZ1

Other Studies

3 other study(ies) available for guanabenz and Nerve Degeneration

ArticleYear
Rescue of ATXN3 neuronal toxicity in
    Disease models & mechanisms, 2017, 12-19, Volume: 10, Issue:12

    Topics: Animals; Animals, Genetically Modified; Ataxin-3; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cinnamates; Endoplasmic Reticulum Stress; Guanabenz; Humans; Longevity; Methylene Blue; Motor Neurons; Mutation; Nerve Degeneration; Oxidative Stress; Paralysis; Phenotype; Protein Aggregates; Repressor Proteins; Small Molecule Libraries; Thiourea; Transgenes; Unfolded Protein Response

2017
Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.
    Neuroscience, 2014, Sep-26, Volume: 277

    Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Animals; Cell Death; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Guanabenz; Mice, Transgenic; Mitochondria; Motor Activity; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Random Allocation; Superoxide Dismutase; Survival Analysis

2014
Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Amyotrophic Lateral Sclerosis; Animals; Antihypertensive Agents; Disease Models, Animal; Disease Progression; eIF-2 Kinase; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Fibroblasts; Guanabenz; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Phosphorylation; Protein Phosphatase 1; Superoxide Dismutase; Tunicamycin; Unfolded Protein Response

2015