guanabenz and Blood Pressure, High

guanabenz has been researched along with Blood Pressure, High in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	72 (79.12)	18.7374
1990's	10 (10.99)	18.2507
2000's	9 (9.89)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hargreaves, RT; Warren, JD; Woodward, DL	1
Jin, X; Kim, JH; Kim, SH; Park, BH; Park, WH; Yuan, K	1
Paul, IA; Peeler, DF; Piletz, JE; Stec, DE; Zhu, H	1
Head, GA	1
Aoki, Y; Araki, T; Chonan, K; Hashimoto, J; Hozawa, A; Imai, Y; Kikuya, M; Matsubara, M; Michimata, M; Nishimura, T; Ohkubo, T; Ugajin, T; Yamaguchi, J	1
Takishita, S; Yamazato, M	1
Sica, DA	1
Lappe, RW; Saslow, BA; Wendt, RL	1
Cervenka, J; Mosley, C; O'Connor, DT; Slutsky, RA; Taylor, A	1
Garg, DC; Jallad, NS; Weidler, DJ	1
Buckalew, VM; Eldridge, JC; Strandhoy, J	1
Drayer, JI; Weber, MA	3
Morgan, TO	1
Deitch, MW; Graves, P; Kilbourne, K; Rath, A; Walson, PD	1
Deitch, MW; Drayer, JI; Weber, MA	1
Kaplan, NM	2
McCarron, DA	1
Frova, C	1
Houston, MC	1
Finnerty, FA	1
Insel, PA; Motulsky, HJ; O'Connor, DT	1
Hamilton, CA; Reid, JL	1
Dziedzic, SW; Elijovich, F; Felton, K; Krakoff, LR; Yeager, K	1
Grenfell, RF	1
Avery, GS; Brogden, RN; Heel, RC; Holmes, B; Speight, TM	1
Bevilacqua, M; Meroni, R; Norbiato, G; Scorza, D; Vago, T	1
Agabiti-Rosei, E; Alicandri, C; Fariello, R; Muiesan, G; Renzetti, I; Romanelli, G	1
Delle Gemme, E; Dessì-Fulgheri, P; Glorioso, N; Madeddu, P; Rappelli, A	1
Antognetti, R; Giovine, GG	1
Frisina, N; Macrì, I; Ussi, F	1
Delle Gemme, E; Misceo, N; Pieri, A; Pirrelli, A; Stella, M; Strippoli, M	1
Masoni, C; Pirani, R; Tomasi, AM	1
Chiang, ST; Emmett, M; Goldberg, M; Kyriakopoulos, AA; Meacham, RH; Narins, RG; Ruelius, HW; Walker, BR	2
Amodio, P; Casiglia, E; Frigo, A; Gatta, A; Hlede, M; Merkel, C; Milani, L; Palatini, P; Pessina, AC; Semplicini, A	1
Argentieri, M; Mazzanti, A	1
Patola, R; Storti, R	1
Alessandrini, A; Bianchi, RM; Legnani, W; Renzetti, I	1
Gehr, M; Goldberg, M; MacCarthy, EP	1
Deitch, MW; Kilbourne, K; Rath, A; Walson, PD	1
Bauer, JH	1
De Ridder, JH; Marchandise, P	1
Chiarini, C; Degli Esposti, E; Gattiani, A; Sturani, A; Zuccalá, A	1
Kluyskens, Y; Snoeck, J	1
Fairchild, C; Gomez-Sanchez, CE; Holland, OB	1
Deitch, MW; Gold, JA; Levey, BA; Walker, BR	1
Rosendorff, C	1
Cavellat, M; Chapillon, M; Delhumeau, A; Leboulanger, J	1
Deitch, MW; Gold, JA; Hare, LE; Schneider, BE; Walker, BR	1
Deitch, MW; Hare, LE; Schneider, BE; Walker, BR	1
Kick, CJ; Kocmund, SM; Meacham, RH; Peters, JR; Ruelius, HW; Sisenwine, SF; Wendt, RL	1
Gold, JA; Rudnick, MR; Schneider, BE; Walker, BR	1
Cloix, JF; Dausse, JP; Le Jossec, M	1
Huang, BS; Leenen, FH	5
Fujita, H; Itoh, H; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K; Takenaka, K; Uchida, A; Yoneda, Y; Yoshitomi, T	1
Endo, T; Hishiki, S; Kawano, Y; Miyajima, E; Shigemasa, T	1
Leenen, FH; Zhang, J	1
Huang, BS; Leenen, FH; Wang, H	1
Jain, AK; McMahon, FG; Ryan, JR; Vanov, SK; Vargas, R	1
Helfant, RH; Ramanathan, KB; Shah, RS; Vanov, SK; Walker, BR	1
Orth, H; Ritz, E; Tschöpe, W	1
Asmal, AC; Leary, WP; Williams, PC	1
Campus, S; Dessì Fulgheri, P; Glorioso, N; Madeddu, P; Rappelli, A; Tedde, R	1
Helfant, RH; Shah, RS; Vanov, SK; Walker, BR	1
Di Veroli, C; Petrucci, D	1
Chiummo, R	1
Abdel-Rahman, AA; Carroll, RG; el-Mas, MM	1
DiBona, GF; Jones, SY	1
Baez, MA; Deitch, MW; Garg, DC; Shapse, DB; Weidler, DJ; Woo-Ming, RB	1
Gehr, M; Goldberg, M	1
Pandhi, P; Sharma, PL	1
DiBona, GF; Johnson, AK; Kapusta, DR; Knardahl, S; Koepke, JP	1
DiBona, GF; Jones, S; Koepke, JP	2
DiBona, GF; Koepke, JP	1
Grundy, S; Kaplan, NM	1
Baso, B; Gac, JC; Román, O; Sudy, E; Valenzuela, MA	1
Rodrigues, R; Spritzer, N; Spritzer, TS	1
Hayashi, S; Nishio, S; Yoshihara, H	1
Jessup, SA; LaRusso, P; Rogers, FJ; Rogers, JC	1
Alvis, R; Braden, G; Cox, M; Walker, BR	1
Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M	1
DeCola, P; Dubrow, A; Flamenbaum, W; Mittman, N; Westerman, M	1

Reviews

7 review(s) available for guanabenz and Blood Pressure, High

Article	Year
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension. Journal of hypertension, 2003, Volume: 21, Issue:4 Topics: Antihypertensive Agents; Circadian Rhythm; Clonidine; Guanabenz; Humans; Hypertension	2003
[Centrally-acting antihypertensive drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3 Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoline Receptors; Kidney; Methyldopa; Norepinephrine; Pressoreceptors; Receptors, Drug; Renal Circulation; Sodium; Sympathetic Nervous System; Sympatholytics; Vascular Resistance	2004
Centrally acting antihypertensive agents: an update. Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:5 Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Oxazoles; Rilmenidine	2007
Centrally acting antihypertensive agents: a brief overview. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Animals; Antihypertensive Agents; Central Nervous System; Clonidine; Guanabenz; Humans; Hypertension; Methyldopa; Reserpine; Sympathetic Nervous System	1984
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome. American heart journal, 1981, Volume: 102, Issue:3 Pt 1 Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Clonidine; Guanabenz; Heart Failure; Humans; Hypertension; Methyldopa; Myocardial Infarction; Pressoreceptors; Prospective Studies; Substance Withdrawal Syndrome; Syndrome; Time Factors	1981
Central and peripheral blockade of the sympathetic nervous system. The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics	1984
Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. Drugs, 1983, Volume: 26, Issue:3 Topics: Animals; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Protein Binding; Tissue Distribution	1983

Trials

30 trial(s) available for guanabenz and Blood Pressure, High

Article	Year
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements. Journal of hypertension, 2003, Volume: 21, Issue:4 Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Clonidine; Female; Guanabenz; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome	2003
Comparative effects of antihypertensive therapy with guanabenz and propranolol on renal vascular resistance and left ventricular mass. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Double-Blind Method; Guanabenz; Guanidines; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Propranolol; Renal Circulation; Vascular Resistance	1984
Dose-response relationship of single oral doses of guanabenz in hypertensive patients. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Administration, Oral; Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Pulse	1984
Endocrinologic effects of antihypertensive therapy with guanabenz or hydrochlorothiazide. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Endocrine System Diseases; Female; Glucagon; Growth Hormone; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Prolactin; Radioimmunoassay	1984
Step-one antihypertensive therapy: a comparison of a centrally acting agent and a diuretic. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Guanabenz; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Risk	1984
Guanabenz (Wytensin) a new antihypertensive drug. The Medical letter on drugs and therapeutics, 1983, Jan-21, Volume: 25, Issue:627 Topics: Clinical Trials as Topic; Guanabenz; Guanidines; Humans; Hypertension	1983
Effect of guanabenz on blood pressure responses to posture and exercise. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:2 Topics: Adult; Blood Pressure; Drug Evaluation; Epinephrine; Female; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; Male; Norepinephrine; Physical Exertion; Posture; Renin	1983
Double-blind study of guanabenz acetate in hypertensive patients. Southern medical journal, 1983, Volume: 76, Issue:2 Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Double-Blind Method; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Random Allocation; Time Factors	1983
[Clinical and statistical considerations on a new drug in the therapy of arterial hypertension. Controlled study]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Mefruside; Middle Aged	1984
[Treatment of arterial hypertension with a new drug combining guanabenz-mefruside]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Mefruside; Middle Aged	1984
[Clinical use of various dosages of a centrally acting hypotensive drug associated with a diuretic]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Tolerance; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Mefruside; Middle Aged	1984
[Treatment of idiopathic hypertension with guanabenz-mefruside]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Mefruside; Middle Aged	1984
[The antihypertensive effect of 2,6-dichloro-benzylidene-aminoguanidine acetate (Guanabenz)]. Giornale di clinica medica, 1980, Volume: 61, Issue:3 Topics: Adult; Clinical Trials as Topic; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Placebos	1980
Comparison of guanabenz and clonidine in hypertensive patients. Current medical research and opinion, 1980, Volume: 6, Issue:9 Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Pulse	1980
Effect of guanabenz and hydrochlorothiazide on blood pressure and plasma renin activity. Journal of clinical pharmacology, 1981, Volume: 21, Issue:4 Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin	1981
Evaluation of guanabenz added to hydrochlorothiazide therapy in hypertension. The Journal of international medical research, 1982, Volume: 10, Issue:3 Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse	1982
Guanabenz versus methyldopa in the therapy of mild-to-moderate hypertension. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Sep-18, Volume: 62, Issue:13 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Methyldopa; Middle Aged	1982
Comparative antihypertensive effects of guanabenz and methyldopa. Clinical therapeutics, 1981, Volume: 4, Issue:4 Topics: Blood Pressure; Body Weight; Double-Blind Method; Drug Evaluation; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Methyldopa; Posture; Random Allocation	1981
Effects of placebo versus guanabenz on hypertensive out-patients. The Journal of international medical research, 1980, Volume: 8, Issue:5 Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Evaluation; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Placebos	1980
Guanabenz in essential hypertension. Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:3 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged	1977
Guanabenz and methyldopa on hypertension and cardiac performance. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:6 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged	1977
[Clinical experiences in antihypertensive treatment with guanabenz or clonidine in combination with thiazide]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diuretics; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors	1978
Evaluation of the efficacy and safety of guanabenz versus clonidine. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jan-20, Volume: 55, Issue:3 Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Evaluation; Guanabenz; Guanidines; Humans; Hypertension; Middle Aged; Pulse	1979
Guanabenz effects on blood pressure and noninvasive parameters of cardiac performance in patients with hypertension. Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:6 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Placebos; Pulse; Time Factors	1976
[Controlled clinical trial of a new antihypertensive drug: 2,6-dichlorobenzylidene-amino-guanidine acetate]. La Clinica terapeutica, 1976, Feb-29, Volume: 76, Issue:4-3 Topics: Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Guanabenz; Guanidines; Humans; Hypertension	1976
Dose-ranging study to delineate the additive antihypertensive effect of guanabenz and captopril. Journal of clinical pharmacology, 1991, Volume: 31, Issue:4 Topics: Administration, Oral; Adult; Blood Pressure; Captopril; Drug Synergism; Drug Therapy, Combination; Female; Guanabenz; Humans; Hypertension; Male; Middle Aged	1991
Comparison of the effects of guanabenz and hydrochlorothiazide on plasma lipids. Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3 Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Guanabenz; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Prospective Studies; Random Allocation; Triglycerides	1988
[Guanabenz in primary hypertension]. Revista medica de Chile, 1988, Volume: 116, Issue:3 Topics: Blood Pressure; Cholesterol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Triglycerides	1988
[Guanabenz acetate and serum lipids. Sequential evaluation during one year]. Arquivos brasileiros de cardiologia, 1988, Volume: 51, Issue:2 Topics: Blood Pressure; Cholesterol; Clinical Trials as Topic; Female; Follow-Up Studies; Guanabenz; Guanidines; Humans; Hypertension; Lipids; Lipoproteins; Male	1988
Guanfacine as monotherapy for systemic hypertension. The American journal of cardiology, 1986, Mar-28, Volume: 57, Issue:9 Topics: Adult; Aged; Aldosterone; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Guanabenz; Guanfacine; Guanidines; Humans; Hypertension; Lipoproteins; Middle Aged; Phenylacetates; Plasma Volume; Random Allocation; Sleep Stages	1986

Other Studies

54 other study(ies) available for guanabenz and Blood Pressure, High

Article	Year
4-Substituted semicarbazones of mono- and dichlorobenzaldehydes as antihypertensive agents. Journal of medicinal chemistry, 1977, Volume: 20, Issue:11 Topics: Animals; Antihypertensive Agents; Benzaldehydes; Dogs; Hypertension; Rats; Semicarbazones; Structure-Activity Relationship	1977
Modification of atrial natriuretic peptide system in cold-induced hypertensive rats. Regulatory peptides, 2009, Apr-10, Volume: 154, Issue:1-3 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cold Temperature; Cyclic AMP; Dose-Response Relationship, Drug; Guanabenz; Heart Atria; Heart Rate; Hypertension; Isoproterenol; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; RNA, Messenger; Sympathetic Nervous System; Time Factors	2009
Non-adrenergic exploratory behavior induced by moxonidine at mildly hypotensive doses. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Brain; Dose-Response Relationship, Drug; Epinephrine; Exploratory Behavior; Guanabenz; Hypertension; Hypotension; Imidazoles; Imidazoline Receptors; Male; Mice; Receptors, Adrenergic, alpha-2; Receptors, Drug; Sympathetic Nervous System	2003
Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Guanabenz; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Nifedipine; Rats; Rats, Inbred SHR	1984
Comparison of a centrally acting antihypertensive agent and beta-adrenergic blocking agents for the treatment of hypertension. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Guanabenz; Humans; Hypertension; Male; Middle Aged; Pindolol; Potassium; Propranolol; Pulse; Time Factors	1984
Effects of guanabenz in adolescent hypertension. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adolescent; Adult; Blood Pressure; Child; Echocardiography; Guanabenz; Guanidines; Humans; Hypertension; Male; Pulse	1984
Hypertension in patients with diabetes mellitus: treatment with a centrally acting agent. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Complications; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Pulse	1984
Effects of guanabenz on plasma lipid levels in hypertensive patients. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adult; Aged; Cholesterol; Female; Guanabenz; Guanidines; Humans; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Time Factors; Triglycerides	1984
[Pharmacologic profile of guanabenz]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Guanabenz; Guanidines; Humans; Hypertension; Receptors, Adrenergic, alpha	1984
Office management of hypertension. Comprehensive therapy, 1984, Volume: 10, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Captopril; Clonidine; Diuretics; Guanabenz; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors	1984
Platelet alpha 2-adrenergic receptors in treated and untreated essential hypertension. Clinical science (London, England : 1979), 1983, Volume: 64, Issue:3 Topics: Adult; Blood Platelets; Guanabenz; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Propranolol; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1983
alpha-Adrenoceptors and hypertension. Biochemical Society transactions, 1982, Volume: 10, Issue:6 Topics: Animals; Catecholamines; Guanabenz; Hypertension; Phenylephrine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1982
[Effects of guanabenz on plasma renin and aldosterone and on sodium balance in hypertensive patients]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aldosterone; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Renin; Sodium	1984
[Effect of guanabenz, alpha 2 central agonist, on the activity of the sympathetic nervous system during dynamic and isometric physical exercise]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Blood Pressure; Exercise Test; Female; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Norepinephrine; Renin	1984
[Effect of guanabenz alone and in association with a diuretic on blood pressure and on the renin-angiotensin-aldosterone system in hypertensive patients]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; Middle Aged; Renin; Renin-Angiotensin System	1984
[Availability of 14C-guanabenz in patients with idiopathic hypertension]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Aged; Biological Availability; Carbon Radioisotopes; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged	1984
[Antihypertensive action and renal effects of guanabenz]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Adult; Guanabenz; Guanidines; Humans; Hypertension; Kidney; Middle Aged	1984
[Efficacy and tolerance of guanabenz in patients with associated chronic cardio-circulatory, respiratory, infectious and metabolic diseases]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Aged; Angina Pectoris; Arterial Occlusive Diseases; Arthritis; Bronchopneumonia; Chronic Disease; Diabetes Complications; Drug Tolerance; Female; Guanabenz; Guanidines; Heart Failure; Humans; Hypertension; Male; Middle Aged; Urinary Tract Infections	1984
[Guanabenz in hypertension in the aged]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Aged; Guanabenz; Guanidines; Humans; Hypertension; Middle Aged; Posture	1984
[Effects of the short-term administration of a new preparation in the treatment of arterial hypertension]. Minerva cardioangiologica, 1984, Volume: 32, Issue:5 Topics: Aged; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Mefruside; Middle Aged	1984
Natriuretic and water diuretic effects of guanabenz, a central alpha-2 agonist. Transactions of the American Clinical and Climatological Association, 1984, Volume: 95 Topics: Adult; Diuresis; Drug Evaluation; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Natriuresis; Time Factors	1984
Guanabenz for adolescent hypertension. Pediatric pharmacology (New York, N.Y.), 1984, Volume: 4, Issue:1 Topics: Adolescent; Adult; Blood Pressure; Child; Drug Evaluation; Guanabenz; Guanidines; Headache; Humans; Hypertension; Male; Pulse	1984
Effects of guanabenz therapy on renal function and body fluid composition. Archives of internal medicine, 1983, Volume: 143, Issue:6 Topics: Blood Pressure; Blood Pressure Determination; Body Fluids; Dose-Response Relationship, Drug; Drug Evaluation; Glomerular Filtration Rate; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Pulse; Vascular Resistance	1983
Preliminary clinical trial with a new hypotensive, guanabenz, in a group of hypertensive patients. Acta cardiologica, 1980, Volume: 35, Issue:5 Topics: Aged; Amiloride; Blood Pressure; Drug Evaluation; Drug Tolerance; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged	1980
[Single dose of thiopental or fentanyl. Hemodynamic effects after treatment by an anti-hypertensive drug: guanoxabenz (author's transl)]. Anesthesie, analgesie, reanimation, 1981, Volume: 38, Issue:3-4 Topics: Aged; Antihypertensive Agents; Craniocerebral Trauma; Drug Interactions; Fentanyl; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Middle Aged; Thiopental	1981
Long-term therapy of hypertension with guanabenz. Clinical therapeutics, 1981, Volume: 4, Issue:3 Topics: Adult; Aged; Body Weight; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Pulse; Time Factors	1981
Disposition of 14C-guanabenz in patients with essential hypertension. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:1 Topics: Adult; Aged; Glucuronates; Guanabenz; Guanidines; Half-Life; Humans; Hypertension; Kinetics; Middle Aged	1980
Relationship of guanabenz concentrations in brain and plasma to antihypertensive effect in the spontaneously hypertensive rat. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:3 Topics: Animals; Blood Pressure; Brain; Dose-Response Relationship, Drug; Guanabenz; Guanidines; Heart Rate; Hypertension; Male; Rats	1980
[Evidence for two alpha 2B-adrenoreceptor isoforms in the renal cortex of salt-sensitive and salt resistant Sabra rats. Effect of salt loading]. Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:8 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Guanabenz; Hypertension; Kidney Cortex; Male; Oxymetazoline; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Sodium, Dietary; Yohimbine	1995
Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in SHR. The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 2 Topics: Air; Animals; Blood Pressure; Brain; Diet, Sodium-Restricted; Guanabenz; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Physical Stimulation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System	1996
Brain "ouabain" and angiotensin II in salt-sensitive hypertension in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:6 Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Brain; Guanabenz; Hemodynamics; Hypertension; Imidazoles; Immunoglobulin Fab Fragments; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles	1996
Role of baroreflex and central alpha2-adrenergic receptor systems in the diurnal variation of blood pressure and heart rate in normotensive and hypertensive rats. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Baroreflex; Blood Pressure; Circadian Rhythm; Denervation; Guanabenz; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-2; Sinoatrial Node	1995
Both brain angiotensin II and "ouabain" contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:6 Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Body Weight; Brain; Cardiotonic Agents; Guanabenz; Hemodynamics; Hypertension; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Inbred Dahl; Sodium Chloride; Stress, Physiological	1998
Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:1 Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteries; Baroreflex; Brain; Guanabenz; Heart; Hypertension; Injections, Intraventricular; Kidney; Lung; Male; Nervous System Diseases; Ouabain; Rats; Rats, Wistar; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System	1999
Guanabenz combination therapy inhibits sympathetic nerve activity and regresses left ventricular hypertrophy. Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:1 Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Guanabenz; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Norepinephrine; Organ Size; Sympathetic Nervous System; Sympatholytics	2000
AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3 Topics: Air Movements; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Chronic Disease; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Stress, Physiological; Sympathetic Nervous System; Vasoconstrictor Agents	2001
Enhanced sympathoexcitatory and pressor responses to central Na+ in Dahl salt-sensitive vs. -resistant rats. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5 Topics: Adrenergic alpha-Agonists; Age Factors; Animals; Baroreflex; Blood Pressure; Brain; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Kidney; Male; Ouabain; Potassium; Rats; Rats, Inbred Dahl; Rats, Wistar; Sodium; Sodium, Dietary; Sympathetic Nervous System	2001
[Effect of guanabenz on arterial pressure and the renin-aldosterone system in hypertensive patients]. Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:1 Topics: Adult; Aged; Aldosterone; Blood Pressure; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Middle Aged; Renin	1978
[Antihypertensive activity of a new molecule, 2,6-dichloro-benzylidene aminoguanidine acetate]. Minerva medica, 1975, Dec-08, Volume: 66, Issue:84 Topics: Aged; Antihypertensive Agents; Drug Evaluation; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Methyldopa; Middle Aged	1975
Role of the sympathetic nervous system in the alcohol-guanabenz hemodynamic interaction. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:9 Topics: Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Guanabenz; Heart Rate; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Hypertension; Hypotension; Male; Nitroprusside; Rats; Rats, Inbred SHR; Sympathetic Nervous System	1992
Central alpha 2-adrenoceptor responsiveness in borderline hypertensive rats. Journal of hypertension, 1991, Volume: 9, Issue:6 Topics: Animals; Brain; Guanabenz; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Sodium, Dietary	1991
Brain ouabain and central effects of dietary sodium in spontaneously hypertensive rats. Circulation research, 1992, Volume: 70, Issue:2 Topics: Animals; Blood Pressure; Brain; Diet; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Kidney; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rest; Sodium; Stress, Psychological; Sympathetic Nervous System	1992
Effects of alpha-2 agonists on renal function in hypertensive humans. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 8 Topics: Adrenergic alpha-Agonists; Clonidine; Diuresis; Glomerular Filtration Rate; Guanabenz; Humans; Hypertension; Kidney; Methyldopa; Natriuresis	1985
Alpha 2-adrenoceptor agonists in the treatment of hypertension. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 8 Topics: Adrenergic alpha-Agonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Lipids; Methyldopa	1985
Progress in the treatment of essential hypertension. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23 Suppl 1 Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Methyldopa; Vasodilator Agents	1985
Selective central alpha-2 adrenoceptor control of regional haemodynamic responses to air jet stress in conscious spontaneously hypertensive rats. Journal of hypertension, 1989, Volume: 7, Issue:3 Topics: Animals; Aorta, Abdominal; Blood Pressure; Central Nervous System; Guanabenz; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Renal Artery; Stress, Physiological; Vascular Resistance	1989
Sodium responsiveness of central alpha 2-adrenergic receptors in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Central Nervous System; Denervation; Diuresis; Dose-Response Relationship, Drug; Guanabenz; Hypertension; Injections, Intraventricular; Kidney; Natriuresis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Sodium, Dietary; Sympathetic Nervous System; Yohimbine	1988
Central adrenergic receptor control of renal function in conscious hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2 Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urodynamics; Yohimbine	1986
Alpha 2-adrenoceptors in amygdala control renal sympathetic nerve activity and renal function in conscious spontaneously hypertensive rats. Brain research, 1987, Feb-24, Volume: 404, Issue:1-2 Topics: Amygdala; Animals; Blood Pressure; Consciousness; Guanabenz; Hypertension; Kidney; Male; Propanolamines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Stress, Physiological; Sympathetic Nervous System; Yohimbine	1987
[Clinical and fundamental study of guanabenz in hypertensive patients with renal failure]. Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:6 Topics: Adult; Aged; Female; Guanabenz; Guanidines; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	1988
Sinoatrial and atrioventricular dysfunction associated with the use of guanabenz acetate. The Canadian journal of cardiology, 1988, Volume: 4, Issue:3 Topics: Aged; Aged, 80 and over; Bradycardia; Cardiac Pacing, Artificial; Female; Guanabenz; Guanidines; Heart Block; Heart Conduction System; Humans; Hypertension; Sinoatrial Block	1988
Effects of guanabenz on sodium and water homeostasis. Journal of clinical hypertension, 1987, Volume: 3, Issue:4 Topics: Adult; Blood Pressure; Creatinine; Guanabenz; Guanidines; Humans; Hypertension; Kidney Concentrating Ability; Male; Middle Aged; Sodium, Dietary; Water-Electrolyte Balance	1987
Safety and efficacy of guanabenz in hypertensive patients with moderate renal insufficiency. Journal of clinical hypertension, 1985, Volume: 1, Issue:4 Topics: Blood Urea Nitrogen; Body Weight; Creatinine; Female; Guanabenz; Guanidines; Humans; Hypertension; Kidney Diseases; Male; Middle Aged	1985
Treatment of hypertension in the elderly. Southern medical journal, 1986, Volume: 79, Issue:3 Topics: Aged; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Guanabenz; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Retrospective Studies; Systole	1986