guaifenesin has been researched along with Status Asthmaticus in 13 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Status Asthmaticus: A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic bronchitis is characterized by mucus hypersecretion." | 2.37 | The pathology of obstructive and inflammatory airway diseases. ( Reid, LM, 1986) |
| "Status asthmaticus respiratory failure is associated with thickened mucus secretions necessitating aggressive pulmonary clearance." | 1.38 | Pediatric fiberoptic bronchoscopy as adjunctive therapy in acute asthma with respiratory failure. ( Babbitt, C; Maggi, FE; Maggi, JC; Nussbaum, E; Randhawa, I, 2012) |
| "Plastic bronchitis is an infrequent cause of acute life-threatening respiratory failure that can mimic foreign body aspiration or status asthmaticus." | 1.32 | Plastic bronchitis mimicking foreign body aspiration that needs a specific diagnostic procedure. ( Brichet, A; Cremer, R; Dorkenoo, A; Fourier, C; Leclerc, F; Leteurtre, S; Noizet, O; Pouessel, G, 2003) |
| "The left-sided atelectasis resolved 3 hrs after the first dose of rhDNase." | 1.31 | Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus. ( Durward, A; Forte, V; Shemie, SD, 2000) |
| " There were no significant differences in age, sex, smoking history, duration of BA history, and dosage of glucocorticoids received between groups A and B." | 1.28 | Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. ( Aikawa, T; Ebina, M; Sasaki, H; Shimura, S; Takishima, T, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maggi, JC | 1 |
| Nussbaum, E | 1 |
| Babbitt, C | 1 |
| Maggi, FE | 1 |
| Randhawa, I | 1 |
| Noizet, O | 1 |
| Leclerc, F | 1 |
| Leteurtre, S | 1 |
| Brichet, A | 1 |
| Pouessel, G | 1 |
| Dorkenoo, A | 1 |
| Fourier, C | 1 |
| Cremer, R | 1 |
| Groneberg, DA | 1 |
| Wagner, U | 1 |
| Chung, KF | 1 |
| Zamanian, M | 1 |
| Marini, JJ | 1 |
| Greally, P | 1 |
| Sheehan, JK | 1 |
| Richardson, PS | 1 |
| Fung, DC | 1 |
| Howard, M | 1 |
| Thornton, DJ | 1 |
| Picado, C | 1 |
| Fahy, JV | 1 |
| Corry, DB | 1 |
| Boushey, HA | 1 |
| Durward, A | 1 |
| Forte, V | 1 |
| Shemie, SD | 1 |
| Aikawa, T | 1 |
| Shimura, S | 1 |
| Sasaki, H | 1 |
| Ebina, M | 1 |
| Takishima, T | 1 |
| Bhaskar, KR | 1 |
| O'Sullivan, DD | 1 |
| Coles, SJ | 1 |
| Kozakewich, H | 1 |
| Vawter, GP | 1 |
| Reid, LM | 2 |
| Niederman, MS | 1 |
| Gambino, A | 1 |
| Lichter, J | 1 |
| Weinblatt, M | 1 |
| Fein, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Beatmungsdauer Und Lungenfunktion Bei Beatmeten Patienten Unter Therapie Mit Dornase Alfa - Randomisierte, Doppel-Blinde, Placebo-Kontrollierte, Multizentrische, Prospektive Klinische Studie[NCT00204685] | Phase 2/Phase 3 | 540 participants | Interventional | 2003-08-31 | Active, not recruiting | ||
| "Validation of a Questionnaire to Assess Bronchial Mucus Hypersecretion in Asthmatic Patients. Questionnaire T-sec (Secretion Test)."[NCT05546645] | 100 participants (Anticipated) | Observational | 2023-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for guaifenesin and Status Asthmaticus
| Article | Year |
|---|---|
Classification of severe asthma exacerbations: a proposal.
Topics: Administration, Inhalation; Administration, Oral; Allergens; Anti-Inflammatory Agents, Non-Steroidal | 1996 |
Airway inflammation and remodeling in asthma.
Topics: Airway Obstruction; Asthma; Basement Membrane; Bronchi; Bronchial Hyperreactivity; Bronchitis; Const | 2000 |
The pathology of obstructive and inflammatory airway diseases.
Topics: Animals; Asthma; Bronchi; Bronchiectasis; Bronchiolitis, Viral; Bronchitis; Child; Dogs; Humans; Lun | 1986 |
10 other studies available for guaifenesin and Status Asthmaticus
| Article | Year |
|---|---|
Pediatric fiberoptic bronchoscopy as adjunctive therapy in acute asthma with respiratory failure.
Topics: Adolescent; Bronchoalveolar Lavage; Bronchoscopy; Child; Child, Preschool; Humans; Infant; Length of | 2012 |
Plastic bronchitis mimicking foreign body aspiration that needs a specific diagnostic procedure.
Topics: Acute Disease; Airway Obstruction; Bronchi; Bronchitis; Bronchoscopy; Causality; Child, Preschool; C | 2003 |
Mucus and fatal asthma.
Topics: Airway Obstruction; Asthma; Cell Count; Goblet Cells; Humans; Mucin 5AC; Mucin-5B; Mucins; Mucus; Re | 2004 |
Pressure-flow signatures of central-airway mucus plugging.
Topics: Adrenal Cortex Hormones; Adult; Airway Obstruction; Airway Resistance; Anti-Bacterial Agents; Bronch | 2006 |
Human recombinant DNase for mucus plugging in status asthmaticus.
Topics: Bronchoscopy; Child; Deoxyribonuclease I; Female; Humans; Mucus; Radiography, Thoracic; Recombinant | 1995 |
Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus.
Topics: Gels; Glycoproteins; Humans; Lung; Male; Microscopy, Electron; Middle Aged; Molecular Weight; Mucins | 1995 |
Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus.
Topics: Bronchoalveolar Lavage; Bronchoscopy; Child; Deoxyribonuclease I; Expectorants; Humans; Instillation | 2000 |
Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack.
Topics: Epithelium; Exocrine Glands; Female; Histocytological Preparation Techniques; Humans; Hyperplasia; L | 1992 |
Characterization of airway mucus from a fatal case of status asthmaticus.
Topics: Adolescent; Airway Obstruction; Asthma; Centrifugation, Density Gradient; Chromatography, Thin Layer | 1988 |
Tension ball valve mucus plug in asthma.
Topics: Adult; Asthma; Female; Humans; Mucus; Positive-Pressure Respiration; Pulmonary Atelectasis; Radiogra | 1985 |