Page last updated: 2024-10-28

guaifenesin and Sneezing

guaifenesin has been researched along with Sneezing in 19 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.

Research Excerpts

ExcerptRelevanceReference
"We used a rhinovirus challenge model to test the therapeutic efficacy of clemastine fumarate for reducing sneezing and nasal secretion in a double-blind, randomized clinical trial."5.08Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds. ( Edelman, DA; Gwaltney, JM; O'Connor, RR; Park, J; Paul, RA; Turner, RB, 1996)
"This paper presents the results of a randomized, double-blind, placebo-controlled study of the efficacy of chlorpheniramine in relieving the symptoms and attenuating the pathophysiologic correlates of a rhinovirus "common cold."5.06A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge. ( Doyle, WJ; Gwaltney, JM; Maddern, BR; McBride, TP; Skoner, DP; Uhrin, M, 1988)
" Itching and the number of sneezes were noted, and the amount of secretion was measured and assayed for substance P."3.67Nasal challenge with serotonin in asymptomatic hay fever patients. ( Mygind, N; Schaffalitzky de Muckadell, OB; Tønnesen, P, 1987)
"A total of 38 hayfever subjects were studied."2.67Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data. ( Cipolla, C; D'Antuono, G; Lugo, G; Occhionero, T; Orciari, P, 1990)
"The efficacy of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarine++ + dihydrochloride) in a dosage of 2 mg o."2.66Double-blind controlled crossover study comparing the protective effect of picumast dihydrochloride versus placebo following nasal allergen challenge. ( Bachert, C; Franke, W; Messinger, D, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's4 (21.05)18.2507
2000's2 (10.53)29.6817
2010's2 (10.53)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Kornder, NA1
Esser, Y1
Stoupin, D1
Leys, SP1
Mueller, B1
Vermeij, MJA1
Huisman, J1
de Goeij, JM1
Cavalcanti, RFP1
Gadelha, FAAF1
de Jesus, TG1
Cavalcante-Silva, LHA1
Paiva Ferreira, LKD1
Paiva Ferreira, LAM1
Vieira, GC1
Piuvezam, MR1
Tan, VYJ1
Zhang, EZY1
Daniel, D1
Sadovoy, A1
Teo, NWY1
Kiong, KL1
Toh, ST1
Yuen, HW1
Guo, L1
Wang, M1
Zhang, L1
Mao, N1
An, C1
Xu, L1
Long, E1
Gustin, KM1
Katz, JM1
Tumpey, TM1
Maines, TR1
Goto, DM1
Lança, M1
Obuti, CA1
Galvão Barbosa, CM1
Nascimento Saldiva, PH1
Trevisan Zanetta, DM1
Lorenzi-Filho, G1
de Paula Santos, U1
Nakagawa, NK1
Watanabe, K1
Misu, T1
Inoue, S1
Edamatsu, H1
Brooks, CD1
Nelson, AL1
Metzler, C1
Borum, P1
Mygind, N2
Gwaltney, JM3
Park, J1
Paul, RA1
Edelman, DA1
O'Connor, RR1
Turner, RB1
Jean, R1
Rufin, P1
Pfister, A1
Landais, P1
Waernessyckle, S1
de Blic, J1
Scheinmann, P1
Lacroix, JS1
Muether, PS1
Proctor, DF1
Adams, GK1
Cohen, AB1
Gold, WM1
Cipolla, C1
Occhionero, T1
Orciari, P1
Lugo, G1
D'Antuono, G1
Tønnesen, P1
Schaffalitzky de Muckadell, OB1
Franke, W1
Bachert, C1
Messinger, D1
Doyle, WJ1
McBride, TP1
Skoner, DP1
Maddern, BR1
Uhrin, M1

Reviews

4 reviews available for guaifenesin and Sneezing

ArticleYear
Transmission risk of viruses in large mucosalivary droplets on the surface of objects: A time-based analysis.
    Infectious diseases now, 2021, Volume: 51, Issue:3

    Topics: Air Microbiology; Bacteria; Cough; COVID-19; Desiccation; Disease Transmission, Infectious; Equipmen

2021
[Environment and nasal hyperreactivity].
    Revue medicale de la Suisse romande, 1999, Volume: 119, Issue:8

    Topics: Capillary Permeability; Environmental Exposure; Humans; Mucus; Neuropeptides; Rhinitis; Sneezing

1999
Physiology and pharmacology of nasal function and mucus secretion.
    Pharmacology & therapeutics. Part B: General & systematic pharmacology, 1976, Volume: 2, Issue:3

    Topics: Airway Obstruction; Anesthetics, Local; Headache; Hearing Disorders; Histamine H1 Antagonists; Human

1976
Defense mechanisms of the lungs.
    Annual review of physiology, 1975, Volume: 37

    Topics: Antigens; Bacterial Infections; Bronchi; Cilia; Cough; Environmental Pollutants; Environmental Pollu

1975

Trials

7 trials available for guaifenesin and Sneezing

ArticleYear
Effect of flurbiprofen, a cyclooxygenase inhibiting drug, on induced allergic rhinitis.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 1

    Topics: Adult; Analysis of Variance; Female; Flurbiprofen; Humans; Middle Aged; Mucus; Nasal Provocation Tes

1984
Inhibition of the immediate allergic reaction in the nose by the beta-2 adrenostimulant fenoterol.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:1

    Topics: Adult; Aerosols; Allergens; Dose-Response Relationship, Drug; Double-Blind Method; Ethanolamines; Fe

1980
Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Clemastine; Common Cold; Double-Blind Method; Female;

1996
Variant effect of first- and second-generation antihistamines as clues to their mechanism of action on the sneeze reflex in the common cold.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Nov-01, Volume: 33, Issue:9

    Topics: Adult; Common Cold; Histamine H1 Antagonists; Humans; Intercellular Adhesion Molecule-1; Loratadine;

2001
Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data.
    Magnesium research, 1990, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Calcium; Evaluation Studies as Topic; Female; Humans; Lacrimal Apparatus; Magnesi

1990
Double-blind controlled crossover study comparing the protective effect of picumast dihydrochloride versus placebo following nasal allergen challenge.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:10A

    Topics: Adult; Coumarins; Double-Blind Method; Histamine H1 Antagonists; Humans; Manometry; Middle Aged; Muc

1989
A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:3

    Topics: Acoustic Impedance Tests; Adult; Chlorpheniramine; Clinical Trials as Topic; Common Cold; Double-Bli

1988

Other Studies

8 other studies available for guaifenesin and Sneezing

ArticleYear
Sponges sneeze mucus to shed particulate waste from their seawater inlet pores.
    Current biology : CB, 2022, 09-12, Volume: 32, Issue:17

    Topics: Animals; Bays; Coral Reefs; Ecosystem; Humans; Mucus; Porifera; Seawater; Sneezing; Water

2022
Warifteine and methylwarifteine inhibited the type 2 immune response on combined allergic rhinitis and asthma syndrome (CARAS) experimental model through NF-кB pathway.
    International immunopharmacology, 2020, Volume: 85

    Topics: Alkaloids; Animals; Anti-Allergic Agents; Asthma; Behavior, Animal; Bronchoalveolar Lavage Fluid; Ci

2020
Respiratory droplet generation and dispersal during nasoendoscopy and upper respiratory swab testing.
    Head & neck, 2020, Volume: 42, Issue:10

    Topics: Administration, Intranasal; COVID-19 Testing; Endoscopy; Humans; Infection Control; Infectious Disea

2020
Comparison of the levels of infectious virus in respirable aerosols exhaled by ferrets infected with influenza viruses exhibiting diverse transmissibility phenotypes.
    Journal of virology, 2013, Volume: 87, Issue:14

    Topics: Animals; Ferrets; Influenza A virus; Mucus; Orthomyxoviridae Infections; Particle Size; Real-Time Po

2013
Effects of biomass burning on nasal mucociliary clearance and mucus properties after sugarcane harvesting.
    Environmental research, 2011, Volume: 111, Issue:5

    Topics: Adult; Agriculture; Air Pollutants, Occupational; Biomass; Humans; Incineration; Male; Middle Aged;

2011
Cytolysis of eosinophils in nasal secretions.
    The Annals of otology, rhinology, and laryngology, 2003, Volume: 112, Issue:2

    Topics: Cell Death; Cell Degranulation; Cell Membrane; Cell Movement; Eosinophil Peroxidase; Eosinophils; Hu

2003
Diagnostic value of nasal provocation challenge with allergens in children.
    Allergy, 1998, Volume: 53, Issue:10

    Topics: Adolescent; Allergens; Antigens, Dermatophagoides; Asthma; Cell Count; Child; Child, Preschool; Conj

1998
Nasal challenge with serotonin in asymptomatic hay fever patients.
    Allergy, 1987, Volume: 42, Issue:6

    Topics: Adult; Airway Resistance; Female; Humans; Male; Mucus; Nasal Mucosa; Nasal Provocation Tests; Prurit

1987