guaifenesin has been researched along with Rhinitis, Allergic, Nonseasonal in 43 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-two non-allergic and 18 allergic patients with nasal polyps were administered clarithromycin 500 mg/day (single oral dose) for eight weeks." | 5.16 | Effect of long-term, low-dose clarithromycin on T helper 2 cytokines, eosinophilic cationic protein and the 'regulated on activation, normal T cell expressed and secreted' chemokine in the nasal secretions of patients with nasal polyposis. ( Matković-Jožin, S; Perić, A; Vojvodić, D, 2012) |
| "Nasal mucociliary clearance was measured using a saccharin technique in 172 patients with perennial rhinitis (76 also had asthma) and in 121 patients with chronic infected rhinosinusitis (40 had asthma, 35 had bronchiectasis)." | 3.67 | Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease. ( Cole, PJ; Greenstone, MA; Mackay, IS; Stanley, PJ; Wilson, R, 1985) |
| "Gross epistaxis is apparent as a red lavage fluid, while microepistaxis may yield a clear fluid." | 1.31 | Nasal lavage concentrations of free hemoglobin as a marker of microepistaxis during nasal provocation testing. ( Baraniuk, JN; Clauw, D; Naranch, K; Park, YJ; Repka-Ramirez, MS; Velarde, A, 2002) |
| "Type I allergy is thought to be involved in the sinusitis which is called allergic sinusitis." | 1.30 | [Clinical features and characteristics of paranasal sinus effusion in allergic sinusitis]. ( Mogi, G; Sakamoto, N; Suko, T; Suzuki, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (27.91) | 18.7374 |
| 1990's | 10 (23.26) | 18.2507 |
| 2000's | 15 (34.88) | 29.6817 |
| 2010's | 6 (13.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erffmeyer, JE | 1 |
| McKenna, WR | 1 |
| Lieberman, PL | 1 |
| Yoo, TJ | 1 |
| Taylor, WW | 1 |
| Gröger, M | 1 |
| Bernt, A | 1 |
| Wolf, M | 1 |
| Mack, B | 1 |
| Pfrogner, E | 1 |
| Becker, S | 1 |
| Kramer, MF | 1 |
| Pignatti, P | 1 |
| Pala, G | 1 |
| Pisati, M | 1 |
| Perfetti, L | 1 |
| Banchieri, G | 1 |
| Moscato, G | 1 |
| Cho, HJ | 1 |
| Lee, HJ | 1 |
| Kim, SC | 1 |
| Kim, K | 1 |
| Kim, YS | 1 |
| Kim, CH | 1 |
| Lee, JG | 1 |
| Yoon, JH | 1 |
| Choi, JY | 1 |
| Gadzhimirzaev, GA | 1 |
| Mikhrailova, ZT | 1 |
| Akhmedov, IG | 1 |
| Muradova, GR | 1 |
| Perić, A | 1 |
| Vojvodić, D | 1 |
| Matković-Jožin, S | 1 |
| Shah, SA | 1 |
| Ishinaga, H | 1 |
| Hou, B | 1 |
| Okano, M | 1 |
| Takeuchi, K | 2 |
| Yang, SH | 1 |
| Hong, CY | 1 |
| Yu, CL | 1 |
| Braun, H | 2 |
| Buzina, W | 2 |
| Freudenschuss, K | 2 |
| Beham, A | 2 |
| Stammberger, H | 2 |
| Watanabe, K | 1 |
| Misu, T | 1 |
| Inoue, S | 1 |
| Edamatsu, H | 1 |
| Rogers, DF | 1 |
| Lackner, A | 1 |
| Shimizu, T | 2 |
| Shimizu, S | 1 |
| Hattori, R | 1 |
| Mashima, Y | 1 |
| Ishida, Y | 1 |
| Nakamura, F | 1 |
| Kanzato, H | 1 |
| Sawada, D | 1 |
| Hirata, H | 1 |
| Nishimura, A | 1 |
| Kajimoto, O | 1 |
| Fujiwara, S | 1 |
| Pant, H | 1 |
| Kette, FE | 1 |
| Smith, WB | 1 |
| Wormald, PJ | 2 |
| Macardle, PJ | 1 |
| Dinh, QT | 1 |
| Cryer, A | 1 |
| Dinh, S | 1 |
| Peiser, C | 1 |
| Wu, S | 1 |
| Springer, J | 1 |
| Hamelmann, E | 1 |
| Klapp, BF | 1 |
| Heppt, W | 1 |
| Fischer, A | 1 |
| Ooi, EH | 1 |
| Carney, AS | 1 |
| James, CL | 1 |
| Tan, LW | 1 |
| Airaksinen, L | 1 |
| Tuomi, T | 1 |
| Vanhanen, M | 1 |
| Voutilainen, R | 1 |
| Toskala, E | 1 |
| McCusker, CT | 1 |
| Wang, Y | 1 |
| Shan, J | 1 |
| Kinyanjui, MW | 1 |
| Villeneuve, A | 1 |
| Michael, H | 1 |
| Fixman, ED | 1 |
| Berger, G | 1 |
| Kogan, T | 1 |
| Skutelsky, E | 1 |
| Ophir, D | 1 |
| Sasaki, Y | 1 |
| Nakahara, H | 1 |
| Hamaguchi, F | 1 |
| Ukai, K | 2 |
| Harada, I | 1 |
| Sakakura, Y | 4 |
| Asakura, K | 3 |
| Enomoto, K | 1 |
| Ara, H | 1 |
| Azuma, E | 1 |
| Kataura, A | 1 |
| Häcki, M | 1 |
| Brändli, O | 1 |
| Mikulewicz, W | 1 |
| Okuda, M | 2 |
| Miura, I | 1 |
| Juji, F | 1 |
| Takashima, H | 1 |
| Hattori, M | 1 |
| Majima, Y | 3 |
| Yoshimi, R | 1 |
| Shinogi, J | 1 |
| Harada, T | 1 |
| Yuta, A | 1 |
| Doyle, WJ | 1 |
| Gaumond, E | 1 |
| Ali, M | 1 |
| Tamarkin, L | 1 |
| Baraniuk, JN | 2 |
| Van Deusen, M | 1 |
| Cohen, S | 1 |
| Skoner, DP | 1 |
| Suzuki, M | 1 |
| Suko, T | 1 |
| Sakamoto, N | 1 |
| Mogi, G | 1 |
| Jean, R | 1 |
| Rufin, P | 1 |
| Pfister, A | 1 |
| Landais, P | 1 |
| Waernessyckle, S | 1 |
| de Blic, J | 1 |
| Scheinmann, P | 1 |
| Ohkubo, K | 1 |
| Ikeda, M | 1 |
| Pawankar, R | 1 |
| Gotoh, M | 1 |
| Yagi, T | 1 |
| Hirano, H | 1 |
| Park, YJ | 1 |
| Repka-Ramirez, MS | 1 |
| Naranch, K | 1 |
| Velarde, A | 1 |
| Clauw, D | 1 |
| Sato, Y | 1 |
| Kojima, T | 2 |
| Tanaka, K | 1 |
| Okamoto, Y | 1 |
| Nagaya, Y | 1 |
| Nishimura, F | 1 |
| Takeoka, A | 1 |
| Hanada, S | 1 |
| Kohno, S | 1 |
| Kawai, M | 1 |
| Armengot, M | 1 |
| Marco, J | 1 |
| Kohno, H | 1 |
| Seyama, Y | 1 |
| Yamashita, S | 1 |
| Aramaki, H | 1 |
| Inoue, H | 1 |
| Yamada, T | 1 |
| Yamada, K | 1 |
| Ishikawa, T | 1 |
| Stanley, PJ | 1 |
| Wilson, R | 1 |
| Greenstone, MA | 1 |
| Mackay, IS | 1 |
| Cole, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation[NCT03673384] | 50 participants (Actual) | Interventional | 2015-03-02 | Completed | |||
| Effect of Traditional Chinese Medicine on Gut Microbiota, Physical Constitution, and Allergic Diseases[NCT03033290] | Phase 3 | 60 participants (Anticipated) | Interventional | 2018-01-10 | Recruiting | ||
| Phase 3 Study of Qi-tonifying Chinese Herbal Products for Treatment of Allergic Rhinitis[NCT01631032] | Phase 3 | 112 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| A Randomized, Double-blind, Placebo-controlled Trial of Lactobacillus Acidophilus L92 on Markers of Allergic Inflammation by Nasal Provocation With Grass Pollen[NCT00554736] | Phase 3 | 0 participants (Actual) | Interventional | 2006-05-31 | Withdrawn (stopped due to Sponsor suspended study do to funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for guaifenesin and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Airway hypersecretion in allergic rhinitis and asthma: new pharmacotherapy.
Topics: Asthma; Capillary Permeability; Chloride Channels; Glucocorticoids; Histamine Antagonists; Humans; M | 2003 |
[The role of eosinophil in nasal allergy].
Topics: Blood Proteins; Cell Degranulation; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophils; | 1993 |
5 trials available for guaifenesin and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Efficacy of phenylephrine-phenylpropanolamine in the treatment of rhinitis.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Guaifenesin; | 1982 |
Effect of long-term, low-dose clarithromycin on T helper 2 cytokines, eosinophilic cationic protein and the 'regulated on activation, normal T cell expressed and secreted' chemokine in the nasal secretions of patients with nasal polyposis.
Topics: Adult; Aged; Anti-Bacterial Agents; Chemokine CCL5; Clarithromycin; Cytokines; Eosinophil Cationic P | 2012 |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs.
Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase 2; Dinopro | 2002 |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs.
Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase 2; Dinopro | 2002 |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs.
Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase 2; Dinopro | 2002 |
The stimulatory effects of nasal discharge from patients with perennial allergic rhinitis on normal human neutrophils are normalized after treatment with a new mixed formula of Chinese herbs.
Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase 2; Dinopro | 2002 |
Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study.
Topics: Animals; Double-Blind Method; Fermentation; Food Handling; Hot Temperature; Humans; Immunoglobulin E | 2005 |
Symposium: The upper airways under attack.
Topics: Administration, Intranasal; Anti-Bacterial Agents; Cilia; Clinical Trials as Topic; Common Cold; Dru | 1983 |
36 other studies available for guaifenesin and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Eosinophils and mast cells: a comparison of nasal mucosa histology and cytology to markers in nasal discharge in patients with chronic sino-nasal diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Chronic Disease; Eosin | 2013 |
Nasal blown secretion evaluation in specific occupational nasal challenges.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Eosinophilia; Eosinophils; Humans; Immunologic Tests; | 2010 |
Protease-activated receptor 2-dependent fluid secretion from airway submucosal glands by house dust mite extract.
Topics: Adolescent; Adult; Aged; Antigens, Dermatophagoides; Carbachol; Exocrine Glands; Female; Humans; Imm | 2012 |
[The role of disturbances of lipid metabolism in pathogenesis of allergic rhinitis].
Topics: Adolescent; Adult; Drug Administration Routes; Drug Therapy, Combination; Female; Histamine H1 Antag | 2011 |
Effects of interleukin-31 on MUC5AC gene expression in nasal allergic inflammation.
Topics: Cell Line; Cell Line, Tumor; Gene Expression Regulation; Humans; Interleukins; Mucin 5AC; Mucus; Nas | 2013 |
'Eosinophilic fungal rhinosinusitis': a common disorder in Europe?
Topics: Chronic Disease; Eosinophilia; Eosinophils; Fungi; Humans; Mucus; Mycoses; Nasal Cavity; Nasal Mucos | 2003 |
Cytolysis of eosinophils in nasal secretions.
Topics: Cell Death; Cell Degranulation; Cell Membrane; Cell Movement; Eosinophil Peroxidase; Eosinophils; Hu | 2003 |
[Incidence and detection of fungi and eosinophilic granulocytes in chronic rhinosinusitis].
Topics: Chronic Disease; Colony Count, Microbial; Diagnosis, Differential; Eosinophilia; Eosinophils; Fungi; | 2003 |
[Effect of azithromycin on mucus secretion from nasal epithelium].
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Cells, Cultured; Depression, Chemical; Disease Models, | 2003 |
Fungal-specific humoral response in eosinophilic mucus chronic rhinosinusitis.
Topics: Adolescent; Adult; Aged; Alternaria; Antibodies, Fungal; Aspergillosis; Aspergillus fumigatus; Chron | 2005 |
Transcriptional up-regulation of histamine receptor-1 in epithelial, mucus and inflammatory cells in perennial allergic rhinitis.
Topics: Adolescent; Adult; Aged; Endothelial Cells; Epithelial Cells; Female; Humans; Male; Middle Aged; Muc | 2005 |
Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and alternaria in a nasal explant model.
Topics: Adult; Aged; Aged, 80 and over; Allergens; Alternaria; Aspergillus fumigatus; Eosinophilia; Female; | 2007 |
Use of nasal provocation test in the diagnostics of occupational rhinitis.
Topics: Acaridae; Adult; Allergens; Animals; Dust; Epithelium; Female; Flour; Fungi; Humans; Irritants; Male | 2007 |
Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide.
Topics: Acute Disease; Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Mo | 2007 |
Glycoconjugate expression in perennial allergic rhinitis: a lectin histopathological study.
Topics: Adult; Biomarkers; Glycoconjugates; Humans; Lectins; Mucus; Nasal Mucosa; Rhinitis, Allergic, Perenn | 2007 |
[Epithelial changes in the nasal mucosa of patients with allergic rhinitis].
Topics: Basement Membrane; Epithelium; Humans; Microscopy, Electron; Mucus; Nasal Mucosa; Rhinitis, Allergic | 1984 |
[Nasal mocosal hypersensitivity to histamine and acetylcholine and histamine content in nasal secretion on manifested and non-manifested nasal allergy].
Topics: Acetylcholine; Adolescent; Child; Child, Preschool; Histamine; Humans; Mucus; Nasal Mucosa; Nasal Pr | 1983 |
Nasal responsiveness to methacholine stimulation in allergic rhinitis patients.
Topics: Administration, Topical; Humans; Methacholine Compounds; Mucus; Nasal Provocation Tests; Rhinitis, A | 1984 |
[Eosinophil concentration in nasal secretion in bronchial asthma].
Topics: Asthma; Diagnosis, Differential; Eosinophils; Humans; Leukocyte Count; Mucus; Nasal Mucosa; Rhinitis | 1981 |
[The effect of the technique of mucosa secretion obtaining on the results of biochemical investigations (author's transl)].
Topics: Adult; Female; Humans; Male; Mucus; Muramidase; Nasal Mucosa; Rhinitis, Allergic, Perennial; Specime | 1980 |
A novel method of counting eosinophils in nasal secretion of allergic rhinitis by hemocytometric method.
Topics: Adult; Blood Cell Count; Eosinophilia; Eosinophils; Humans; Leukocyte Count; Mucins; Mucus; Nasal Mu | 1994 |
Effects of nasal allergen challenge on dynamic viscoelasticity of nasal mucus.
Topics: Adolescent; Adult; Allergens; Child; Dust; Elasticity; Female; Humans; Male; Mucus; Nasal Provocatio | 1993 |
Quantitative cytology of nasal secretions with perennial allergic rhinitis in children: comparison of noninfected and infected conditions.
Topics: Adolescent; Animals; Child; Child, Preschool; Eosinophils; Female; Humans; Leukocyte Count; Male; Mi | 1998 |
Rhinovirus infection induces mucus hypersecretion.
Topics: Adolescent; Adult; Alcian Blue; Coloring Agents; Exocytosis; Glycoproteins; Humans; Immunoglobulin G | 1998 |
[Clinical features and characteristics of paranasal sinus effusion in allergic sinusitis].
Topics: Adolescent; Adult; Aged; Eosinophils; Female; Humans; Hypersensitivity; Interleukin-5; Leukocyte Cou | 1998 |
Diagnostic value of nasal provocation challenge with allergens in children.
Topics: Adolescent; Allergens; Antigens, Dermatophagoides; Asthma; Cell Count; Child; Child, Preschool; Conj | 1998 |
Mechanisms of IL-6, IL-8, and GM-CSF release in nasal secretions of allergic patients after nasal challenge.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans | 1998 |
A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production.
Topics: Animals; Antigens; Chlorpheniramine; Chromones; Cimetidine; Dexamethasone; Eosinophils; Histamine H1 | 2000 |
Nasal lavage concentrations of free hemoglobin as a marker of microepistaxis during nasal provocation testing.
Topics: Adult; Albumins; Anti-Inflammatory Agents; Biomarkers; Epistaxis; Erythrocytes; Female; Hemoglobins; | 2002 |
Improved staining method of the mast cell, etc. in nasal secretion.
Topics: Eosinophils; Humans; Mast Cells; Mucus; Nasal Mucosa; Neutrophils; Rhinitis, Allergic, Perennial; St | 1979 |
[The study of chemical mediators in the patients with allergic rhinitis 2). Histamine, leukotriene and kinins in the nasal secretion during dual phase response].
Topics: Adult; Female; Histamine; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Kinins; Le | 1991 |
[The study of chemical mediators in the patients with allergic rhinitis. 1). Histamine, leukotriene and kinins in the nasal secretion during early phase response].
Topics: Acute-Phase Reaction; Adolescent; Adult; Female; Histamine; Humans; Kinins; Male; Middle Aged; Mucus | 1990 |
A nasal allergy model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate.
Topics: Administration, Intranasal; Animals; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine; Male; | 1988 |
[Changes in nasal mucociliary clearance in normal subject and in patients with various nasal pathologies].
Topics: Adolescent; Adult; Aged; Cilia; Female; Humans; Male; Middle Aged; Mucus; Nasal Mucosa; Rhinitis; Rh | 1987 |
[Effects of iodine-enriched egg (IE-egg) on nasal allergy: basic and clinical investigations].
Topics: Alkaloids; Animals; Azo Compounds; Benzylisoquinolines; Eggs; Female; Food, Fortified; Glucuronidase | 1986 |
Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease.
Topics: Adolescent; Adult; Asthma; Bronchiectasis; Cilia; Female; Humans; Male; Middle Aged; Mucus; Nose; Rh | 1985 |