guaifenesin has been researched along with Reperfusion Injury in 19 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral treatment with geraniol significantly decreased the number of ulcerative lesions induced by ischemia/reperfusion injury by 71 % and the duodenal ulcers induced by cysteamine by 68 %." | 3.80 | Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa. ( Beserra, FP; Bonamin, F; da Rocha, LR; de Carvalho, KI; de Sousa, DP; Dos Santos, RC; Filho, JM; Hiruma-Lima, CA; Périco, LL, 2014) |
| "The effect of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) on gastric secretion and gastric cytoprotection was evaluated using five different models of gastric ulcers: acetic acid-induced chronic gastric ulcers, pylorus ligation, ethanol-induced, indomethacin-induced and ischemia-reperfusion-induced gastric ulcers." | 3.74 | Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats. ( Asad, M; Hrishikeshavan, HJ; Pathak, R; Prasad, S, 2007) |
| "Clonidine was used to decrease mucus production associated with an ischemia/reoxygenation insult." | 1.29 | The role of the mucus gel layer in intestinal bacterial translocation. ( Dunlap, JP; Jackson, RJ; Maxson, RT; Smith, SD; Tryka, F, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amagase, K | 1 |
| Yoshida, Y | 1 |
| Hara, D | 1 |
| Murakami, T | 1 |
| Takeuchi, K | 1 |
| de Carvalho, KI | 1 |
| Bonamin, F | 3 |
| Dos Santos, RC | 1 |
| Périco, LL | 1 |
| Beserra, FP | 1 |
| de Sousa, DP | 1 |
| Filho, JM | 1 |
| da Rocha, LR | 1 |
| Hiruma-Lima, CA | 1 |
| Fishman, JE | 1 |
| Levy, G | 1 |
| Alli, V | 1 |
| Zheng, X | 1 |
| Mole, DJ | 1 |
| Deitch, EA | 2 |
| Pinheiro Silva, L | 1 |
| Damacena de Angelis, C | 1 |
| Kushima, H | 2 |
| José Mininel, F | 1 |
| Campaner Dos Santos, L | 1 |
| Karina Delella, F | 1 |
| Luis Felisbino, S | 1 |
| Vilegas, W | 1 |
| Regina Machado da Rocha, L | 1 |
| Aparecido Dos Santos Ramos, M | 1 |
| Maria Bauab, T | 1 |
| Toma, W | 1 |
| Akiko Hiruma-Lima, C | 1 |
| Ozkan, O | 2 |
| Bektas, G | 1 |
| Cinpolat, A | 1 |
| Bassorgun, I | 1 |
| Ciftcioglu, A | 1 |
| Diebel, ME | 1 |
| Diebel, LN | 1 |
| Manke, CW | 1 |
| Liberati, DM | 1 |
| Whittaker, JR | 1 |
| Qin, X | 1 |
| Sheth, SU | 1 |
| Sharpe, SM | 1 |
| Dong, W | 1 |
| Lu, Q | 1 |
| Xu, D | 1 |
| Gou, L | 1 |
| Zhang, L | 1 |
| Yin, C | 1 |
| Jia, G | 1 |
| Yin, X | 1 |
| Zhuang, X | 1 |
| Xu, X | 1 |
| Liu, Y | 1 |
| Freitas, FF | 1 |
| Fernandes, HB | 1 |
| Piauilino, CA | 1 |
| Pereira, SS | 1 |
| Carvalho, KI | 1 |
| Chaves, MH | 1 |
| Soares, PM | 1 |
| Miura, LM | 1 |
| Leite, JR | 1 |
| Oliveira, RC | 1 |
| Oliveira, FA | 1 |
| Campanholle, G | 1 |
| Silva, RC | 1 |
| Martins, JO | 1 |
| Landgraf, MA | 1 |
| Paiva, VN | 1 |
| Ferreira, RR | 1 |
| Amano, MT | 1 |
| Hiyane, MI | 1 |
| Cenedeze, MA | 1 |
| Pacheco-Silva, A | 1 |
| Camara, NO | 1 |
| Landgraf, RG | 1 |
| Oliveira, IS | 1 |
| da Silva, FV | 1 |
| Viana, AF | 1 |
| dos Santos, MR | 1 |
| Quintans-Júnior, LJ | 1 |
| Martins, Mdo C | 1 |
| Nunes, PH | 1 |
| Oliveira, Fde A | 1 |
| Oliveira, Rde C | 1 |
| Falcão, Hde S | 1 |
| Maia, GL | 1 |
| Moraes, TM | 1 |
| Hiruma Lima, CA | 1 |
| Takayama, C | 1 |
| Ferreira, AL | 1 |
| Souza Brito, AR | 1 |
| Agra, Mde F | 1 |
| Barbosa Filho, JM | 1 |
| Batista, LM | 1 |
| Xie, YC | 1 |
| Tang, F | 1 |
| Pathak, R | 1 |
| Asad, M | 1 |
| Hrishikeshavan, HJ | 1 |
| Prasad, S | 1 |
| Bülbül, M | 1 |
| Tan, R | 1 |
| Gemici, B | 1 |
| Ongüt, G | 1 |
| Izgüt-Uysal, VN | 1 |
| Seno, K | 1 |
| Joh, T | 1 |
| Yokoyama, Y | 1 |
| Itoh, M | 1 |
| Maxson, RT | 1 |
| Dunlap, JP | 1 |
| Tryka, F | 1 |
| Jackson, RJ | 1 |
| Smith, SD | 1 |
| Mojzis, J | 1 |
| Hegedüsová, R | 1 |
| Mirossay, L | 1 |
| Kim, H | 1 |
| Hwan Kim, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alteration of Intestinal Microflora and Efficacy and Safety of Fecal Microbiota Transplantation for Severe Acute Pancreatitis[NCT03015467] | Phase 1/Phase 2 | 80 participants (Anticipated) | Interventional | 2016-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 other studies available for guaifenesin and Reperfusion Injury
| Article | Year |
|---|---|
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage; | 2013 |
Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa.
Topics: Acyclic Monoterpenes; Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Duodenum; Ethanol; Fla | 2014 |
The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Disease Models, Animal; Disease Progression; Ileum; | 2014 |
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Caribbean Region; Disease Models, An | 2015 |
The Relationship Between Ischemia Time and Mucous Secretion in Vaginal Reconstruction With the Jejunal Free Flap: An Experimental Study on the Rat Jejunum.
Topics: Animals; Female; Free Tissue Flaps; Gynecologic Surgical Procedures; Ischemia; Jejunum; Male; Mucus; | 2015 |
Early tranexamic acid administration: A protective effect on gut barrier function following ischemia/reperfusion injury.
Topics: Apoptosis; Caco-2 Cells; Coculture Techniques; Flow Cytometry; Humans; In Vitro Techniques; Intestin | 2015 |
The mucus layer is critical in protecting against ischemia-reperfusion-mediated gut injury and in the restitution of gut barrier function.
Topics: Animals; Intestinal Mucosa; Male; Mucus; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injur | 2011 |
Protective effect of L-citrulline against acute gastric mucosal lesions induced by ischemia-reperfusion in rats.
Topics: Amidines; Animals; Arginine; Benzylamines; Celiac Artery; Citrulline; Enzyme Inhibitors; Gastric Muc | 2011 |
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Eth | 2011 |
Modulation of lung allergic response by renal ischemia and reperfusion injury.
Topics: Animals; Blood Cell Count; Bronchoalveolar Lavage Fluid; Creatinine; Cyclooxygenase 2; Hypersensitiv | 2012 |
Gastroprotective activity of carvacrol on experimentally induced gastric lesions in rodents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cymenes; Disease | 2012 |
Gastroprotective mechanisms of the chloroform and ethyl acetate phases of Praxelis clematidea (Griseb.) R.M.King & H.Robinson (Asteraceae).
Topics: Acetates; Animals; Anti-Ulcer Agents; Asteraceae; Biomarkers; Chloroform; Cytoprotection; Disease Mo | 2013 |
[Experimental study on protecting intestinal barrier function of Huoxiang Zhengqi soft capsule].
Topics: Animals; Capsules; Drug Combinations; Drugs, Chinese Herbal; Female; Hindlimb; Ileum; Intestinal Muc | 2004 |
Effect of peroxisome proliferator-activated receptor-alpha agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bezafibrate; Ethanol; Gastric Acid; Gastric Mucosa; Indomet | 2007 |
Effect of orexin-a on ischemia-reperfusion-induced gastric damage in rats.
Topics: Animals; Dinoprostone; Female; Gastric Mucosa; Intracellular Signaling Peptides and Proteins; Lipid | 2008 |
Role of mucus in gastric mucosal injury induced by local ischemia/reperfusion.
Topics: Acetylcysteine; Alcian Blue; Animals; Chromium Radioisotopes; Diterpenes; Edetic Acid; Gastric Mucos | 1995 |
The role of the mucus gel layer in intestinal bacterial translocation.
Topics: Animals; Clonidine; Escherichia coli; Gels; Intestinal Mucosa; Male; Microscopy, Electron; Mucins; M | 1994 |
Role of mucus in ischemia/reperfusion-induced gastric mucosal injury in rats.
Topics: Animals; Gastric Mucosa; Male; Mucus; Rats; Rats, Wistar; Reperfusion Injury; Stomach | 2000 |
Role of nitric oxide and mucus in ischemia/reperfusion-induced gastric mucosal injury in rats.
Topics: Animals; Arginine; Cyclic GMP; Gastric Mucosa; Glutathione; Glutathione Peroxidase; Lipid Peroxides; | 2001 |