Page last updated: 2024-10-28

guaifenesin and Pulmonary Hypertension

guaifenesin has been researched along with Pulmonary Hypertension in 5 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

Excerpt	Relevance	Reference
"Chronic obstructive pulmonary disease (COPD) is characterized by poorly reversible airflow limitation associated with airway remodelling and inflammation of both large and small airways."	2.47	[Structural abnormalities and inflammation in COPD: a focus on small airways]. ( Bourdin, A; Burgel, PR; Chanez, P; Garcia, G; Pilette, C; Tillie-Leblond, I, 2011)
"Roflumilast evidently has several pharmacological effects: antiinflammatory, anti-emphysema, and antibiotic actions."	2.46	[Pharmacological profile of roflumilast]. ( Cortijo Gimeno, J; Morcillo Sánchez, E, 2010)

Trial	Phase	Enrollment	Study Type	Start Date	Status
The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy as Well as Stand-alone Therapy in Patients With Respiratory Insufficiency[NCT03081650]		30 participants (Anticipated)	Interventional	2016-08-16	Recruiting
Effects of Long-term Dry and Humidified Low-flow Oxygen Via Nasal Cannula on Nasal Mucociliary Clearance, Mucus Properties, Inflammation and Airway Symptoms in Patients[NCT02515786]	Phase 1/Phase 2	19 participants (Anticipated)	Interventional	2013-01-31	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

3 reviews available for guaifenesin and Pulmonary Hypertension

Article	Year
[Pharmacological profile of roflumilast]. Archivos de bronconeumologia, 2010, Volume: 46 Suppl 10 Topics: Airway Remodeling; Aminopyridines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Cel	2010
A view on imaging in drug research and development for respiratory diseases. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2 Topics: Animals; Clinical Trials as Topic; Diagnostic Imaging; Disease Models, Animal; Drug Delivery Systems	2011
[Structural abnormalities and inflammation in COPD: a focus on small airways]. Revue des maladies respiratoires, 2011, Volume: 28, Issue:6 Topics: Adaptive Immunity; Airway Remodeling; Apoptosis; Autoimmunity; Bronchioles; Chemotaxis, Leukocyte; C	2011

1 trial available for guaifenesin and Pulmonary Hypertension

Article	Year
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function. Chest, 2016, Volume: 150, Issue:2 Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac	2016
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function. Chest, 2016, Volume: 150, Issue:2 Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac	2016
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function. Chest, 2016, Volume: 150, Issue:2 Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac	2016
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function. Chest, 2016, Volume: 150, Issue:2 Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac	2016

1 other study available for guaifenesin and Pulmonary Hypertension

Article	Year
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 47-1973. The New England journal of medicine, 1973, Nov-22, Volume: 289, Issue:21 Topics: Aged; Autopsy; Bronchi; Cardiomegaly; Diagnosis, Differential; Female; Humans; Hypercapnia; Hyperten	1973