Page last updated: 2024-10-28

guaifenesin and Pain

guaifenesin has been researched along with Pain in 24 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"A model of visceral pain consisting of intraperitoneal injection of acetic acid (writhing test) was used."3.75Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice. ( Dolezal, T; Krsiak, M; Sliva, J; Sykora, D; Vosmanska, M, 2009)
"Patients with circular rectal tumors seldom had long-term palliative effects of cryosurgery."2.69Palliative cryosurgery for rectal carcinoma. ( Meijer, S; Rahusen, FD; van der Plas, LG, 1999)
"Although rectal pain is often not commonly associated with prolapse, it bothers many women and motivates older women to undergo evaluation."1.62Rectal Prolapse: Age-Related Differences in Clinical Presentation and What Bothers Women Most. ( Arnow, KD; Gurland, BH; Lee, A; Neshatian, L; Trickey, AW, 2021)
" Colon-targeted, intraluminal delivery of 5-HT(4)R agonists might be used to promote motility and alleviate visceral pain, while restricting systemic bioavailability and resulting adverse side effects."1.38Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity. ( Balemba, OB; Brooks, EM; Galligan, JJ; Greenwood-Van Meerveld, B; Hoffman, JM; Johnson, AC; MacEachern, SJ; Mawe, GM; Moses, PL; Sharkey, KA; Swain, GM; Tyler, K; Zhao, H, 2012)
"Few patients with anorectal foreign bodies will freely admit to transanal introduction."1.30Management of anorectal foreign bodies: a cause of obscure anal pain. ( Eu, KW; Ho, YH; Leong, A; Nyam, D; Ooi, BS; Seow-Choen, F, 1998)
"The tracheo-bronchial mucus viscosity was also significantly reduced (bronchitic animals) as was the fucose and total protein content."1.282-(2,3-Dihydro-5-acetoxy-4,6,7-tribenzofuranyl)acetic acid (IRFI 016): a new antioxidant mucoactive drug. ( Giannetti, P; Paesano, A; Scuri, R, 1990)
"THE CYSTADENOMAS WERE OF TWO TYPES: 1 Tumours with small loculi lined by cubical epithelium, in which there was little secretion of mucus by the epithelium but abundant mucoid stroma."1.24Cystadenoma and cystadenocarcinoma of the pancreas. ( CAMPBELL, JA; CRUICKSHANK, AH, 1962)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's4 (16.67)18.2507
2000's3 (12.50)29.6817
2010's2 (8.33)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Sliva, J1
Dolezal, T1
Sykora, D1
Vosmanska, M1
Krsiak, M1
Sofia, RD1
Coelho Thomazi, GO1
da Costa, A1
Rodrigues, JP1
Alves, GJ1
Prezotto Neto, JP1
de Oliveira Turíbio, T1
Rocha, AM1
da Silva Aires, R1
Seibert, CS1
Spencer, PJ1
Galisteo Júnior, AJ1
de Andrade Júnior, HF1
do Nascimento, N1
Neshatian, L1
Lee, A1
Trickey, AW1
Arnow, KD1
Gurland, BH1
Cooperstein, E1
Gilbert, J1
Epstein, JB1
Dietrich, MS1
Bond, SM1
Ridner, SH1
Wells, N1
Cmelak, A1
Murphy, BA1
Hoffman, JM1
Tyler, K1
MacEachern, SJ1
Balemba, OB1
Johnson, AC1
Brooks, EM1
Zhao, H1
Swain, GM1
Moses, PL1
Galligan, JJ1
Sharkey, KA1
Greenwood-Van Meerveld, B1
Mawe, GM1
Yeoh, EE1
Fraser, RJ1
McGowan, RE1
Botten, RJ1
Di Matteo, AC1
Roos, DE1
Penniment, MG1
Borg, MF1
CAMPBELL, JA1
CRUICKSHANK, AH1
Baraniuk, JN1
Petrie, KN1
Le, U1
Tai, CF1
Park, YJ1
Yuta, A1
Ali, M1
Vandenbussche, CJ1
Nelson, B1
Fletcher, BD1
Abramowsky, CR1
Ooi, BS1
Ho, YH1
Eu, KW1
Nyam, D1
Leong, A1
Seow-Choen, F1
Meijer, S1
Rahusen, FD1
van der Plas, LG1
Sheridan, JL1
Brewer, DW1
Scuri, R1
Giannetti, P1
Paesano, A1
Talley, NJ1
Phillips, SF1
Melton, LJ1
Mulvihill, C1
Wiltgen, C1
Zinsmeister, AR1
Marcus, SN1
Heaton, KW1
Meeroff, JC1
Plumley, PF1
Francis, B1
Ruiz de Aguiar Gonzalez, A1
Audibert Mena, L1
Pratt, JH1
Rubio, B1
Mischler, TW1
Berman, E2
Andersen, IB1
Lundqvist, GR1
Jensen, PL1
Proctor, DF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Complications in the Management and Removal of Rectal and Vaginal Foreign Bodies[NCT05888363]78 participants (Actual)Observational2020-12-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for guaifenesin and Pain

ArticleYear
Vaginal atresia corrected by use of small and large bowel.
    Clinical obstetrics and gynecology, 1972, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Child; Coitus; Colon, Sigmoid; Female; Genital Neoplasms, Female; Hemorrhage; Hum

1972

Trials

2 trials available for guaifenesin and Pain

ArticleYear
Evidence for efficacy without increased toxicity of hypofractionated radiotherapy for prostate carcinoma: early results of a Phase III randomized trial.
    International journal of radiation oncology, biology, physics, 2003, Mar-15, Volume: 55, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Defecation; Dose Fractionation, Radiation; Gastrointestin

2003
Palliative cryosurgery for rectal carcinoma.
    International journal of colorectal disease, 1999, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Cryosurgery; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged

1999

Other Studies

21 other studies available for guaifenesin and Pain

ArticleYear
Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.
    Neuro endocrinology letters, 2009, Volume: 30, Issue:3

    Topics: Acetic Acid; Analgesia; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cele

2009
Effect of glyceryl guaiacolate in animal models of inflammation and pain.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Guaifenesin; Male;

1980
Paratrygon aiereba irradiated anti-mucus serum reduce edematogenic activity induced in experimental model.
    Toxicon : official journal of the International Society on Toxinology, 2020, Apr-30, Volume: 178

    Topics: Animals; Bites and Stings; Brazil; Edema; Elasmobranchii; Enzyme-Linked Immunosorbent Assay; Fresh W

2020
Rectal Prolapse: Age-Related Differences in Clinical Presentation and What Bothers Women Most.
    Diseases of the colon and rectum, 2021, Volume: 64, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Fecal Incontinence; Female; Gastrointestinal Hemorrhage; Human

2021
Vanderbilt Head and Neck Symptom Survey version 2.0: report of the development and initial testing of a subscale for assessment of oral health.
    Head & neck, 2012, Volume: 34, Issue:6

    Topics: Appetite; Chemoradiotherapy; Cohort Studies; Cross-Sectional Studies; Deglutition Disorders; Dentin

2012
Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity.
    Gastroenterology, 2012, Volume: 142, Issue:4

    Topics: Administration, Oral; Analgesics; Animals; Chlorides; Chromosomes, Artificial, Bacterial; Colon; Dis

2012
Cystadenoma and cystadenocarcinoma of the pancreas.
    Journal of clinical pathology, 1962, Volume: 15

    Topics: Cell Transformation, Neoplastic; Cystadenocarcinoma; Cystadenoma; Epithelium; Female; Gastrointestin

1962
Neuropathology in rhinosinusitis.
    American journal of respiratory and critical care medicine, 2005, Jan-01, Volume: 171, Issue:1

    Topics: Acute Disease; Administration, Intranasal; Adult; Albumins; Dose-Response Relationship, Drug; Fatigu

2005
Contrast enemas in cystic fibrosis: implications of appendiceal nonfilling.
    AJR. American journal of roentgenology, 1981, Volume: 137, Issue:2

    Topics: Abdomen; Adolescent; Adult; Appendicitis; Child; Child, Preschool; Contrast Media; Cystic Fibrosis;

1981
Management of anorectal foreign bodies: a cause of obscure anal pain.
    The Australian and New Zealand journal of surgery, 1998, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Anal Canal; Anesthesia, General; Bronchopneumonia; Colon, Sigmoid; Consciou

1998
Obstructions of the intestinal tract.
    The Nursing clinics of North America, 1975, Volume: 10, Issue:1

    Topics: Anxiety; Auscultation; Blood Volume; Dehydration; Gastric Juice; Gastric Mucosa; Humans; Intestinal

1975
Early diagnostic signs and symptoms of laryngeal disease.
    The Laryngoscope, 1975, Volume: 85, Issue:3

    Topics: Aphonia; Cough; Deglutition Disorders; Dyspnea; Epiglottis; Glottis; Headache; Hemoptysis; Hemorrhag

1975
2-(2,3-Dihydro-5-acetoxy-4,6,7-tribenzofuranyl)acetic acid (IRFI 016): a new antioxidant mucoactive drug.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:12

    Topics: Abscess; Animals; Antioxidants; Benzofurans; Bronchi; Carbon Tetrachloride Poisoning; Carrageenan; C

1990
Diagnostic value of the Manning criteria in irritable bowel syndrome.
    Gut, 1990, Volume: 31, Issue:1

    Topics: Colonic Diseases, Functional; Defecation; Diagnosis, Differential; Dyspepsia; Evaluation Studies as

1990
Irritable bowel-type symptoms in spontaneous and induced constipation.
    Gut, 1987, Volume: 28, Issue:2

    Topics: Adult; Anthraquinones; Cathartics; Colonic Diseases, Functional; Constipation; Dietary Fiber; Female

1987
Ulcer disease etiopathogenesis: an eclectic theory.
    Medical hypotheses, 1986, Volume: 19, Issue:2

    Topics: Cell Division; Diet; Gastric Acid; Gastric Mucosa; Growth Substances; Humans; Hydrogen-Ion Concentra

1986
Dietary management of diverticular disease.
    Journal of the American Dietetic Association, 1973, Volume: 63, Issue:5

    Topics: Aged; Bread; Colon, Sigmoid; Defecation; Diet Therapy; Diverticulum; Diverticulum, Colon; Evaluation

1973
[The irritable colon. A retrospective study of 217 cases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-20, Volume: 116, Issue:38

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Cicatrix; Colonic Diseases, Functional; Constip

1974
Further experience with a once-a-month oral contraceptive: quinestrol-quingestanol.
    Fertility and sterility, 1972, Volume: 23, Issue:10

    Topics: Administration, Oral; Adult; Breast; Contraceptives, Oral; Drug Combinations; Female; Fertility; Hea

1972
Human response to controlled levels of sulfur dioxide.
    Archives of environmental health, 1974, Volume: 28, Issue:1

    Topics: Adult; Airway Resistance; Atmosphere Exposure Chambers; Environmental Exposure; Humans; Male; Mucus;

1974
The once-a-month pill.
    The Journal of reproductive medicine, 1970, Volume: 5, Issue:5

    Topics: Abdomen, Acute; Biopsy; Breast; Chile; Contraceptives, Oral; Dosage Forms; Drug Combinations; Endome

1970