guaifenesin has been researched along with Otitis Media with Effusion in 31 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interleukin-8 (IL-8), a potent neutrophilic chemoattractant and inflammatory cytokine, is present in middle ear effusions (MEEs) of children with otitis media and is thought to be responsible for the accumulation of neutrophils in MEEs." | 7.69 | Interleukin-8 concentration predicts the neutrophil count in middle ear effusion. ( Izzo, AA; Nassif, PS; Nicklaus, PJ; Simpson, SQ, 1997) |
| "Interleukin-8 (IL-8), a potent neutrophilic chemoattractant and inflammatory cytokine, is present in middle ear effusions (MEEs) of children with otitis media and is thought to be responsible for the accumulation of neutrophils in MEEs." | 3.69 | Interleukin-8 concentration predicts the neutrophil count in middle ear effusion. ( Izzo, AA; Nassif, PS; Nicklaus, PJ; Simpson, SQ, 1997) |
| "Chronic sinusitis is often the result of bacterial infections that lead to chronic inflammation with thickening of the sinus mucosa and hypersecretion of mucus." | 2.42 | Clinical implications of the immunomodulatory effects of macrolides on sinusitis. ( Majima, Y, 2004) |
| "Ectodermal dysplasia is a rare group of diseases presenting special problems in management for the otolaryngologist, but the full spectrum of otorhinolaryngologic manifestations has been previously unrecognized in the otolaryngologic literature." | 2.38 | Ectodermal dysplasia: the otolaryngologic manifestations and management. ( Potsic, WP; Siegel, MB, 1990) |
| "Middle ear effusion was obtained from children with otitis media with effusion and separated into thick (mucoid) and thin (serous) pools." | 2.37 | Mucolytic agents and otitis media with effusion. ( Birchall, JP; Fitzgerald, JE; Green, GG; Pearson, JP, 1988) |
| "serous middle ear effusions (MEEs)." | 1.48 | Characterization of mucoid and serous middle ear effusions from patients with chronic otitis media: implication of different biological mechanisms? ( Anna, K; Brown, K; Gordish-Dressman, H; Nino, G; Pérez-Losada, M; Poley, M; Preciado, D; Val, S, 2018) |
| "Seventeen mucoid middle ear effusions were collected from the tympanic cavity of 15 cats 1 or 2 weeks after tubal obstruction." | 1.28 | Rheological properties of middle ear mucus in relation to goblet cell population in cat. ( Hamaguchi, Y; Jin, CS; Juhn, SK; Majima, Y; Sakakura, Y; Takeuchi, K, 1991) |
| "Sixteen of 28 middle ear effusions demonstrated significant amounts of MMS." | 1.28 | Macrophage (monocyte)-derived mucous secretagougue (MMS) is released into the fluid of the middle ear of patients with otitis media with effusion. ( Bernstein, JM; Goswami, S; Marom, Z, 1990) |
| "The properties of pooled thick and thin middle ear effusions, from children with otitis media with effusion, were studied by viscometry." | 1.28 | Rheologic studies on middle ear effusions and their mucus glycoproteins. ( Birchall, JP; FitzGerald, JE; Green, GG; Pearson, JP, 1989) |
| "Middle ear effusion was obtained from children with chronic secretory otitis media undergoing myringotomy." | 1.27 | Characterization of human middle ear mucus glycoprotein in chronic secretory otitis media (CSOM). ( Birchall, JP; FitzGerald, JE; Green, GG; Pearson, JP; Stafford, FW, 1987) |
| "Although the treatment of chronic middle ear effusion in children by paracentesis and the insertion of a ventilator tube is popular, it is well recognized that this method does not always provide a cure." | 1.26 | Middle ear effusions: a consideration of factors involved in their aetiology, maintenance and treatment. ( Smyth, GD, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Val, S | 1 |
| Poley, M | 1 |
| Anna, K | 1 |
| Nino, G | 1 |
| Brown, K | 1 |
| Pérez-Losada, M | 1 |
| Gordish-Dressman, H | 1 |
| Preciado, D | 1 |
| Malaty, J | 1 |
| Antonelli, PJ | 3 |
| Westine, JG | 2 |
| Giannoni, CM | 2 |
| Gajewski, B | 1 |
| Majima, Y | 3 |
| Sanabria, J | 1 |
| Márquez, F | 1 |
| Gutiérrez, R | 1 |
| Cenjor, C | 1 |
| Wong, J | 1 |
| Hawke, M | 1 |
| Van Cauwenberge, P | 1 |
| Giebink, GS | 2 |
| Le, CT | 1 |
| Paparella, MM | 2 |
| Berger, G | 1 |
| Nassif, PS | 1 |
| Simpson, SQ | 1 |
| Izzo, AA | 1 |
| Nicklaus, PJ | 1 |
| Lin, J | 1 |
| Vambutas, A | 1 |
| Haruta, A | 1 |
| Kim, Y | 1 |
| Pospiech, L | 1 |
| Jaworska, M | 1 |
| Kubacka, M | 1 |
| Chung, MH | 1 |
| Choi, JY | 1 |
| Lee, WS | 1 |
| Kim, HN | 1 |
| Yoon, JH | 1 |
| Smyth, GD | 1 |
| Gamble, JE | 1 |
| Bizal, JA | 1 |
| Daetwyler, EP | 1 |
| Palva, T | 2 |
| Taskinen, E | 1 |
| Lehtinen, T | 2 |
| Ramsay, H | 1 |
| Björksten, F | 1 |
| Hackman, P | 1 |
| Jin, CS | 2 |
| Takeuchi, K | 2 |
| Hamaguchi, Y | 2 |
| Sakakura, Y | 2 |
| Juhn, SK | 2 |
| Luntz, M | 1 |
| Levit, I | 1 |
| Sadé, J | 1 |
| Bernstein, JM | 1 |
| Goswami, S | 1 |
| Marom, Z | 1 |
| Siegel, MB | 1 |
| Potsic, WP | 2 |
| Elwany, S | 1 |
| Marriott, C | 1 |
| FitzGerald, JE | 3 |
| Green, GG | 3 |
| Birchall, JP | 3 |
| Pearson, JP | 3 |
| Basterra, J | 1 |
| Carbonell, R | 1 |
| Armengot, M | 1 |
| Matoses, S | 1 |
| Stafford, FW | 1 |
| Halmepuro, L | 1 |
| Marsh, RR | 1 |
| Baranak, CC | 1 |
4 reviews available for guaifenesin and Otitis Media with Effusion
| Article | Year |
|---|---|
Clinical implications of the immunomodulatory effects of macrolides on sinusitis.
Topics: Anti-Bacterial Agents; Chronic Disease; Humans; Immunologic Factors; Macrolides; Mucus; Nasal Polyps | 2004 |
Mucus physiopathology, update and new therapeutic tendencies.
Topics: Drug Therapy; Humans; Mucus; Otitis Media with Effusion; Sinusitis | 2004 |
Ectodermal dysplasia: the otolaryngologic manifestations and management.
Topics: Acute Disease; Ectodermal Dysplasia; Humans; Infant; Male; Mucus; Nasal Obstruction; Nose Diseases; | 1990 |
Mucolytic agents and otitis media with effusion.
Topics: Amino Acids; Child; Child, Preschool; Expectorants; Glycoproteins; Humans; In Vitro Techniques; Infa | 1988 |
1 trial available for guaifenesin and Otitis Media with Effusion
| Article | Year |
|---|---|
Symposium: The upper airways under attack.
Topics: Administration, Intranasal; Anti-Bacterial Agents; Cilia; Clinical Trials as Topic; Common Cold; Dru | 1983 |
26 other studies available for guaifenesin and Otitis Media with Effusion
| Article | Year |
|---|---|
Characterization of mucoid and serous middle ear effusions from patients with chronic otitis media: implication of different biological mechanisms?
Topics: Blood Proteins; Child; Child, Preschool; Chronic Disease; Complement System Proteins; DNA, Bacterial | 2018 |
Effect of blood and mucus on tympanostomy tube biofilm formation.
Topics: Bacteriology; Biofilms; Blood Proteins; Cerebrospinal Fluid Otorrhea; Fibronectins; Humans; In Vitro | 2008 |
Defining tympanostomy tube plugs.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Humans; Middle Ear Ventilation; Monosaccharides; | 2002 |
Opening plugged tympanostomy tubes.
Topics: Equipment Design; Middle Ear Ventilation; Mucus; Otitis Media with Effusion; Postoperative Complicat | 2002 |
The cytopathology of middle ear effusions (a new technique).
Topics: Blood Cell Count; Cell Separation; Ear, Middle; Exudates and Transudates; Humans; Microscopy, Electr | 1983 |
Otitis media with effusion. Functional morphology and physiopathology of the structures involved.
Topics: Adolescent; Adult; Aged; Animals; Bacterial Infections; Child; Child, Preschool; Dogs; Ear, Middle; | 1982 |
Epidemiology of otitis media with effusion in children.
Topics: Child; Child, Preschool; Humans; Infant; Mucus; Otitis Media; Otitis Media with Effusion; Otitis Med | 1982 |
Eustachian tube submucosal glands in normal and pathological temporal bones.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chronic Disease; Eusta | 1993 |
Interleukin-8 concentration predicts the neutrophil count in middle ear effusion.
Topics: Adolescent; Analysis of Variance; Cell Count; Chemotaxis, Leukocyte; Child; Child, Preschool; Enzyme | 1997 |
Pneumococcus activation of the 5-lipoxygenase pathway and production of glycoproteins in the middle ear of rats.
Topics: Animals; Arachidonate 5-Lipoxygenase; Ear, Middle; Enzyme Activation; Gene Expression; Glycoproteins | 1999 |
Soluble L-selectin and interleukin-8 in otitis media with effusion.
Topics: Adolescent; Child; Child, Preschool; Drainage; Female; Humans; Infant; Interleukin-8; L-Selectin; Ma | 2000 |
Compositional difference in middle ear effusion: mucous versus serous.
Topics: Child; Child, Preschool; Ear, Middle; Female; Humans; Immunoglobulin A, Secretory; Interleukin-8; Ma | 2002 |
Middle ear effusions: a consideration of factors involved in their aetiology, maintenance and treatment.
Topics: Air; Bacterial Infections; Cholesteatoma; Cilia; Ear Diseases; Ear, Middle; Eustachian Tube; Humans; | 1978 |
Otitis media and chronic middle ear effusion in the asthmatic pediatric patient.
Topics: Adolescent; Asthma; Child; Child, Preschool; Chronic Disease; Ear, Middle; Humans; Infant; Middle Ea | 1992 |
Mast cells and histamine in adenoid tissue and middle ear.
Topics: Adenoids; Chronic Disease; Ear, Middle; Epithelium; Histamine; Humans; Mast Cells; Mucous Membrane; | 1991 |
Rheological properties of middle ear mucus in relation to goblet cell population in cat.
Topics: Animals; Cats; Cell Count; Ear, Middle; Elasticity; Models, Biological; Mucous Membrane; Mucus; Otit | 1991 |
Effects of endotoxin and neutrophil lysate on experimental otitis media with effusion in cats.
Topics: Animals; Cats; Cytological Techniques; Ear, Middle; Elasticity; Endotoxins; Epithelial Cells; Escher | 1991 |
The histological patterns of normal and inflamed middle ear mucosa.
Topics: Child, Preschool; Exocrine Glands; Humans; Infant; Infant, Newborn; Inflammation; Mucus; Otitis Medi | 1991 |
Macrophage (monocyte)-derived mucous secretagougue (MMS) is released into the fluid of the middle ear of patients with otitis media with effusion.
Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; Ear, Middle; Glycoproteins; Humans; Infant; Mi | 1990 |
Tympanic neurectomy: its effects on the seromucinous glands of the middle ear of cats.
Topics: Animals; Cats; Ear, Middle; Exocrine Glands; Microscopy, Electron; Middle Ear Ventilation; Mucous Me | 1990 |
Mucolytic agents for glue ear.
Topics: Acetylcysteine; Administration, Oral; Carbocysteine; Child; Cysteine; Humans; In Vitro Techniques; M | 1985 |
Rheologic studies on middle ear effusions and their mucus glycoproteins.
Topics: Acetylcysteine; Carbocysteine; Child; Glycoproteins; Humans; In Vitro Techniques; Mercaptoethanol; M | 1989 |
[Immunologic study of the nasal mucus and secretion in chronic otitis media with closed tympanum].
Topics: Chronic Disease; Ear, Middle; Humans; Immunoglobulins; Mucus; Nasal Mucosa; Otitis Media with Effusi | 1988 |
Characterization of human middle ear mucus glycoprotein in chronic secretory otitis media (CSOM).
Topics: Child; Child, Preschool; Ear, Middle; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Humans; In | 1987 |
Immunoglobulin E in mucoid secretory otitis media.
Topics: Child; Child, Preschool; Chronic Disease; Humans; Immunoglobulin A; Immunoglobulin E; Immunoglobulin | 1985 |
Hearing loss and visco-elasticity of middle ear fluid.
Topics: Animals; Cochlear Microphonic Potentials; Elasticity; Female; Guinea Pigs; Hearing Loss; Hearing Los | 1985 |