Page last updated: 2024-10-28

guaifenesin and Nasal Obstruction

guaifenesin has been researched along with Nasal Obstruction in 15 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.

Research Excerpts

ExcerptRelevanceReference
"In a recent study, we showed that intranasal capsaicin spray gives a significant and long-term reduction of symptoms in nonallergic noninfectious perennial rhinitis patients."9.10Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study. ( Blom, HM; Boeke, EL; Fokkens, WJ; Keizer, JM; Mulder, PG; Van Rijswijk, JB, 2003)
"In a recent study, we showed that intranasal capsaicin spray gives a significant and long-term reduction of symptoms in nonallergic noninfectious perennial rhinitis patients."5.10Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study. ( Blom, HM; Boeke, EL; Fokkens, WJ; Keizer, JM; Mulder, PG; Van Rijswijk, JB, 2003)
"We used a rhinovirus challenge model to test the therapeutic efficacy of clemastine fumarate for reducing sneezing and nasal secretion in a double-blind, randomized clinical trial."5.08Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds. ( Edelman, DA; Gwaltney, JM; O'Connor, RR; Park, J; Paul, RA; Turner, RB, 1996)
"Ectodermal dysplasia is a rare group of diseases presenting special problems in management for the otolaryngologist, but the full spectrum of otorhinolaryngologic manifestations has been previously unrecognized in the otolaryngologic literature."2.38Ectodermal dysplasia: the otolaryngologic manifestations and management. ( Potsic, WP; Siegel, MB, 1990)
"Rhinolithiasis is the presence of mineralized and calcareous formations located in the nasal cavity."1.33The importance of rigid nasal endoscopy in the diagnosis and treatment of rhinolithiasis. ( Bayram, I; Caksen, H; Dülger, H; Etlik, O; Kiriş, M; Sakin, YF; Yuca, K, 2006)
"A total of 248 patients with mucoviscidosis (cystic fibrosis, CF) were assessed by means of nasal endoscopy."1.30Chronic rhinosinusitis in cystic fibrosis (mucoviscidosis). ( Brihaye, P; Clement, PA; Jorissen, M, 1997)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (46.67)18.2507
2000's5 (33.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, Z1
Ma, J1
DeConde, AS1
Mace, JC1
Alt, JA1
Soler, ZM1
Orlandi, RR1
Smith, TL1
Passali, D1
Astore, S1
Boccuzzi, S1
Loglisci, M1
Cannatelli, A1
Passali, GC1
Bellussi, L1
van Spronsen, E1
Ingels, KJ1
Jansen, AH1
Graamans, K1
Fokkens, WJ3
Van Rijswijk, JB1
Boeke, EL1
Keizer, JM1
Mulder, PG2
Blom, HM1
Yuca, K1
Caksen, H1
Etlik, O1
Bayram, I1
Sakin, YF1
Dülger, H1
Kiriş, M1
Suzuki, M1
Saito, K1
Min, WP1
Vladau, C1
Toida, K1
Itoh, H1
Murakami, S1
Nishioka, GJ1
Barbero, GJ1
König, P1
Parsons, DS1
Cook, PR1
Davis, WE1
Wilhelmson, B1
Gwaltney, JM1
Park, J1
Paul, RA1
Edelman, DA1
O'Connor, RR1
Turner, RB1
Brihaye, P1
Jorissen, M1
Clement, PA1
Braat, JP1
van Wijk, RG1
Rijntjes, E1
Jean, R1
Rufin, P1
Pfister, A1
Landais, P1
Waernessyckle, S1
de Blic, J1
Scheinmann, P1
Olnes, SQ1
Schwartz, RH1
Bahadori, RS1
Siegel, MB1
Potsic, WP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis[NCT01332136]966 participants (Actual)Observational2011-04-30Completed
Efficacy of Bimodal Visual-Olfactory Training in Participants With COVID-19 Resultant Hyposmia or Anosmia Using Participant-Preferred Scents[NCT04710394]240 participants (Actual)Interventional2021-01-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for guaifenesin and Nasal Obstruction

ArticleYear
Evidence-based recommendations regarding the differential diagnosis and assessment of nasal congestion: using the new GRADE system.
    Allergy, 2008, Volume: 63, Issue:7

    Topics: Diagnosis, Differential; Evidence-Based Medicine; Humans; Medical History Taking; Mucus; Nasal Mucos

2008
Ectodermal dysplasia: the otolaryngologic manifestations and management.
    International journal of pediatric otorhinolaryngology, 1990, Volume: 19, Issue:3

    Topics: Acute Disease; Ectodermal Dysplasia; Humans; Infant; Male; Mucus; Nasal Obstruction; Nose Diseases;

1990

Trials

4 trials available for guaifenesin and Nasal Obstruction

ArticleYear
Investigation of change in cardinal symptoms of chronic rhinosinusitis after surgical or ongoing medical management.
    International forum of allergy & rhinology, 2015, Volume: 5, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Canada; Chronic Disease; Cohort Studies; Endo

2015
Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study.
    Allergy, 2003, Volume: 58, Issue:8

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Capsaicin; Double-Blind Method; Female; Humans;

2003
Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Clemastine; Common Cold; Double-Blind Method; Female;

1996
Intranasal cold dry air is superior to histamine challenge in determining the presence and degree of nasal hyperreactivity in nonallergic noninfectious perennial rhinitis.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:6 Pt 1

    Topics: Adult; Cold Temperature; Cross-Over Studies; Female; Histamine; Humans; Male; Mucus; Nasal Cavity; N

1998

Other Studies

9 other studies available for guaifenesin and Nasal Obstruction

ArticleYear
Chronic purulent nasal discharge.
    BMJ (Clinical research ed.), 2017, 05-03, Volume: 357

    Topics: Chronic Disease; Female; Humans; Middle Aged; Mucus; Mycetoma; Nasal Cavity; Nasal Mucosa; Nasal Obs

2017
Values of SP-A protein in the nasal mucosa.
    HNO, 2016, Volume: 64, Issue:9

    Topics: Adult; Biomarkers; Female; Humans; Male; Middle Aged; Mucus; Nasal Mucosa; Nasal Obstruction; Pulmon

2016
The importance of rigid nasal endoscopy in the diagnosis and treatment of rhinolithiasis.
    Auris, nasus, larynx, 2006, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Child; Endoscopy; Epistaxis; Female; Headache; Humans; Lithiasis; Male; Middle Ag

2006
Identification of viruses in patients with postviral olfactory dysfunction.
    The Laryngoscope, 2007, Volume: 117, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Coronavirus; Female; Follow-Up Studies; Herpesvirus 4, Human; Humans

2007
Symptom outcome after functional endoscopic sinus surgery in patients with cystic fibrosis: a prospective study.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:4

    Topics: Activities of Daily Living; Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Endoscopy;

1995
[Mucus and blocked up nose are the best protection against virus].
    Lakartidningen, 1994, Dec-21, Volume: 91, Issue:51-52

    Topics: Adult; Child; Humans; Mucus; Nasal Mucosa; Nasal Obstruction; Rhinitis; Sinusitis

1994
Chronic rhinosinusitis in cystic fibrosis (mucoviscidosis).
    Acta oto-rhino-laryngologica Belgica, 1997, Volume: 51, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Chron

1997
Diagnostic value of nasal provocation challenge with allergens in children.
    Allergy, 1998, Volume: 53, Issue:10

    Topics: Adolescent; Allergens; Antigens, Dermatophagoides; Asthma; Cell Count; Child; Child, Preschool; Conj

1998
Consultation with the specialist: Diagnosis and management of the newborn and young infant who have nasal obstruction.
    Pediatrics in review, 2000, Volume: 21, Issue:12

    Topics: Choanal Atresia; Female; Gastroesophageal Reflux; Hamartoma; Humans; Infant; Infant, Newborn; Male;

2000