Page last updated: 2024-10-28

guaifenesin and Muscular Dystrophy, Duchenne

guaifenesin has been researched along with Muscular Dystrophy, Duchenne in 3 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mizunoya, W1
Upadhaya, R1
Burczynski, FJ1
Wang, G1
Anderson, JE1
Kravitz, RM1
Toussaint, M1
De Win, H1
Steens, M1
Soudon, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparison of Three Methods for Improving Expiratory Cough Flow and Lung Volume in Children With Neuromuscular Diseases[NCT02342132]40 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for guaifenesin and Muscular Dystrophy, Duchenne

ArticleYear
Airway clearance in Duchenne muscular dystrophy.
    Pediatrics, 2009, Volume: 123 Suppl 4

    Topics: Acute Disease; Airway Obstruction; Child; Cough; Humans; Mucus; Muscular Dystrophy, Duchenne; Respir

2009

Trials

1 trial available for guaifenesin and Muscular Dystrophy, Duchenne

ArticleYear
Effect of intrapulmonary percussive ventilation on mucus clearance in duchenne muscular dystrophy patients: a preliminary report.
    Respiratory care, 2003, Volume: 48, Issue:10

    Topics: Administration, Inhalation; Adolescent; Adult; Cross-Over Studies; Female; Humans; Intermittent Posi

2003

Other Studies

1 other study available for guaifenesin and Muscular Dystrophy, Duchenne

ArticleYear
Nitric oxide donors improve prednisone effects on muscular dystrophy in the mdx mouse diaphragm.
    American journal of physiology. Cell physiology, 2011, Volume: 300, Issue:5

    Topics: Animals; Body Weight; Calcinosis; Diaphragm; Female; Guaifenesin; Isosorbide Dinitrate; Male; Mice;

2011