Page last updated: 2024-10-28

guaifenesin and Lung Diseases, Obstructive

guaifenesin has been researched along with Lung Diseases, Obstructive in 153 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"Theophylline can increase the transepithelial secretion of fluid into the respiratory tract lumen by stimulating the chloride pump which is controlled by cyclic AMP."3.76Theophylline and mucociliary clearance. ( Ziment, I, 1987)
"Ambroxol was effective in only 1 of 5 tested lung areas and did not prove to enhance whole lung clearance significantly."2.65Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD. ( Dorow, P; Felix, R; Weiss, T, 1981)
"Chronic bronchitis is characterized by mucociliary dysfunction resulting from structural and functional defects of cilia and the secretory apparatus."2.38The role of mucus in chronic obstructive pulmonary disease. ( Wanner, A, 1990)
"Mucoobstructive lung diseases have highlighted the importance of a proper description of the normal mucus clearance system."1.42On the Pathogenesis of Acute Exacerbations of Mucoobstructive Lung Diseases. ( Boucher, RC, 2015)

Research

Studies (153)

TimeframeStudies, this research(%)All Research%
pre-199081 (52.94)18.7374
1990's35 (22.88)18.2507
2000's16 (10.46)29.6817
2010's16 (10.46)24.3611
2020's5 (3.27)2.80

Authors

AuthorsStudies
Kokkola, K1
Vaara, J1
Medici, TC1
Chodosh, S1
Wynne, JW1
Kim, N1
Kwak, G1
Rodriguez, J1
Livraghi-Butrico, A2
Zuo, X1
Simon, V1
Han, E1
Shenoy, SK1
Pandey, N1
Mazur, M1
Birket, SE1
Kim, A1
Rowe, SM1
Boucher, R1
Hanes, J1
Suk, JS1
Most, JF1
Boyton, RJ1
Altmann, DM1
Boucher, RC5
Brown, R1
Paulsen, M1
Schmidt, S1
Schatterny, J1
Frank, A1
Hirtz, S1
Delaney, R1
Doherty, D1
Hagner, M1
Taggart, C1
Weldon, S1
Mall, MA3
Pieper, M1
Schulz-Hildebrandt, H1
Hüttmann, G1
König, P1
Morrison, L4
Milroy, S1
Werdiger, F1
Donnelley, M1
Dubsky, S1
Murrie, RP1
Carnibella, RP1
Samarage, CR1
How, YY1
Zosky, GR1
Fouras, A1
Parsons, DW1
Morgan, KS1
Innes, S1
Lewis, BW1
Sultana, R1
Sharma, R1
Noël, A1
Langohr, I1
Patial, S1
Penn, AL1
Saini, Y1
Kim, V1
Evans, CM1
Dickey, BF1
Danahay, H1
Li, E1
Landers, CT1
Tung, HY1
Knight, JM1
Marshall, Z1
Luong, AU1
Rodriguez, A1
Kheradmand, F1
Corry, DB1
Rettmer, H1
Hoffman, AM1
Lanz, S1
Oertly, M1
Gerber, V1
Agnew, J2
Klier, J1
Lehmann, B1
Fuchs, S1
Reese, S1
Hirschmann, A1
Coester, C1
Winter, G1
Gehlen, H1
Nishimoto, Y1
Hisatsune, A1
Katsuki, H1
Miyata, T1
Yokomizo, K1
Isohama, Y1
Burgel, PR1
Nadel, JA2
Grubb, BR1
Kelly, EJ1
Wilkinson, KJ1
Yang, H1
Geiser, M1
Randell, SH1
O'Neal, WK1
Cohn, L1
Hamelin, ME1
Prince, GA1
Gomez, AM1
Kinkead, R1
Boivin, G1
Panitch, HB1
Hauber, HP2
Foley, SC1
Hamid, Q1
Fink, JB1
Chatburn, RL1
Zabel, P1
Davis, PB2
Kaliner, M2
Marom, Z1
Patow, C1
Shelhamer, J1
Proto, AV1
Puchelle, E3
Zahm, JM3
Rasche, B6
Hochstrasser, K3
Duvivier, C1
Didelon, J1
Arnould, JP1
Kopp, C1
Obrecht, B1
Peto, R1
Speizer, FE1
Cochrane, AL1
Moore, F1
Fletcher, CM1
Tinker, CM1
Higgins, IT1
Gray, RG1
Richards, SM1
Gilliland, J1
Norman-Smith, B1
Weiss, T5
Dorow, P5
Felix, R5
Thorsen, J1
Willoughby, RA1
McDonell, W1
Valli, VE1
Viel, L1
Bignell, W1
Reynolds, HY1
Bake, B1
Mossberg, B3
Camner, P4
Zimmermann, I1
Sutton, PP1
Pavia, D2
Bateman, JR1
Clarke, SW2
Carubelli, R1
Sachdev, GP1
Fox, OF1
Wen, G1
Horton, FO1
Rogers, RM1
Yeates, DB1
Jenssen, AO1
Smidsrød, O1
Harbitz, O1
Prescott, E2
Lange, P6
Vestbo, J7
Ambrosino, N1
Callegari, G1
Galloni, C1
Brega, S1
Pinna, G1
Lundgren, JD1
van Alphen, L1
Jansen, HM1
Dankert, J1
Bennett, WD1
Zeman, KL1
Pon, DJ1
van Staden, CJ1
Boulet, L1
Rodger, IW1
Sasaki, H3
Itabashi, S1
Fukushima, T1
Sekizawa, K1
Hansen, LG1
Warwick, WJ1
Hansen, KL1
Hasani, A1
Agnew, JE1
Evrensel, CA1
Khan, RU1
Elli, S1
Krumpe, PE1
Polu, JM1
Chabot, F1
Wallaert, B1
Chern, MS1
Chen, FJ1
Chang, SC1
Borer, H1
Frey, M1
Keller, R1
Prescott, EI1
Rothe, TB1
Frey, JG1
Ciobanu, TD1
Karrer, W1
Cambach, W1
Chadwick-Straver, RV1
Wagenaar, RC1
van Keimpema, AR1
Kemper, HC1
Hardy, KA1
Anderson, BD1
Ruzal-Shapiro, C1
Löfdahl, CG1
Bonnert, RV1
Brown, RC1
Chapman, D1
Cheshire, DR1
Dixon, J1
Ince, F1
Kinchin, EC1
Lyons, AJ1
Davis, AM1
Hallam, C1
Harper, ST1
Unitt, JF1
Dougall, IG1
Jackson, DM1
McKechnie, K1
Young, A1
Simpson, WT1
Del Donno, M1
Olivieri, D1
Markewitz, BA1
Owens, MW1
Payne, DK1
Koga, T1
Oizumi, K1
Sethi, S1
Rogers, DF2
Miravitlles, M1
Guerrero, T1
Mayordomo, C1
Sánchez-Agudo, L1
Nicolau, F1
Segú, JL1
Pistelli, F1
Viegi, G1
Johnson, M1
Rennard, S1
Maestrelli, P1
Saetta, M1
Mapp, CE1
Fabbri, LM1
Sackner, MA4
Masala, C1
Amendolea, MA1
Bonini, S1
Curschmann, P1
Thurlbeck, WM4
Lopez-Vidriero, MT1
Ulmer, WT2
Shim, C1
Bajwa, S1
Williams, MH1
Goodman, RM2
Yergin, BM2
Landa, JF1
Golivanux, MH1
Tao, LC1
Sill, V1
Novak, D1
Kaukel, E1
Lanser, K1
Grebenikova, AT1
Kostiuchenko, AL1
Bignon, J2
Depierre, A2
André-Bougaran, J1
Hem, B1
Dixon, PM1
Girod, S1
Galabert, C1
Lecuire, A1
Groth, S1
Mortensen, J1
Nyboe, J2
Appleyard, M2
Jensen, G2
Schnohr, P2
Bergofsky, EH1
Wiles, FJ1
Hnizdo, E1
Jeffery, PK1
Bury, T1
Corhay, JL1
Radermecker, MF1
Wanner, A1
Knudsen, KM1
Rasmussen, FV2
Aikawa, T1
Shimura, S1
Takishima, T1
Yaegashi, H1
Takahashi, T1
Matthys, H2
Daikeler, G2
Krauss, B1
Vastag, E2
Hahn, HL1
Niewoehner, DE1
Distefano, SM1
Palermo, F1
Crimi, N1
Mistretta, A1
Pamparana, F1
Messa, A1
Ziment, I1
Lieberman, D1
Kieberman, D1
Pride, NB1
Finkbeiner, WE1
Basbaum, CB1
Braga, PC1
Allegra, L1
Afzelius, B1
Kamishima, K1
Tashiro, N1
Kawakami, Y1
Furudate, M1
Kneussl, M1
Wieser, O1
Wieser, CO1
Didkovskiĭ, NA1
Dvoretskiĭ, LI1
Remacle, P1
Bruart, J1
Henneghien, C1
van der Schans, CP1
Piers, DA1
Postma, DS1
Köhler, D1
Gronbeck, L1
Greenstone, M1
Cole, PJ1
Nagai, A1
West, WW1
Paul, JL1
Köhler, M1
Maxwell, GM1
Levy, D1
Carey, JP1
Turino, GM1
Reichert, R1
Hochgesand, K1
Lourenço, RV1
Hogg, JC1
Schlenker, JD1
Hubay, CA1
Santa Cruz, R1
Landa, J1
Hirsch, J1
Bateman, PP1
Takizawa, T1
Licht, W2
Struckmeier, HF1
Trendelenburg, F1
Holley, HS1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of High-Frequency Chest Wall Oscillation Using the Vest Airway Clearance System Compared to Conventional Chest Physical Therapy at Barnes-Jewish Hospital[NCT00717873]105 participants (Actual)Interventional2008-06-30Completed
Timing of Hypertonic Saline Inhalation Relative to Airways Clearance in Cystic Fibrosis[NCT01753869]14 participants (Actual)Interventional2012-12-31Terminated (stopped due to Challenges with recruitment)
Evaluation of the Short-term Use of Selected PEP and OPEP Devices in Cystic Fibrosis Patients During an Exacerbation of the Disease[NCT05801952]60 participants (Anticipated)Interventional2020-01-01Recruiting
Air Stacking Technique For Pulmonary Reexpansion In The Ventilator After Expiratory Pause During Aspiration In Closed System[NCT05702411]39 participants (Anticipated)Interventional2021-09-01Recruiting
The Instantaneous Effects of High-Frequency Chest Wall Oscillation on Patients With Acute Pneumonic Respiratory Failure Receiving Mechanical Ventilation[NCT02758106]73 participants (Actual)Interventional2014-02-28Completed
The Feasibility and Efficacy of Heated Humidified Nasal Cannula (AIRVOTM) in Hospital and at Home - An Open-Label, Non-Randomized Pilot Study.[NCT03772626]30 participants (Anticipated)Interventional2019-02-25Active, not recruiting
A Preliminary Randomized Trial of the FreeAspire Versus PEP-bottle After Acute Exacerbation in COPD Patients With Mucus Hypersecretion and Decreased Cough Efficiency.[NCT02640430]40 participants (Actual)Interventional2016-10-31Completed
Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD[NCT02282202]32 participants (Actual)Interventional2013-09-30Completed
Can High Frequency Chest Wall Oscillation Accelerate the Discharged of Intubated Intensive Care Patients?[NCT02645695]30 participants (Actual)Interventional2014-02-28Completed
Effect of Expiratory Positive Airway Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD Patients[NCT03073564]19 participants (Actual)Interventional2015-12-01Completed
Percussion Palm Cup: Safety and Usability of Newly Designed Products in Infants and Children With Cystic Fibrosis[NCT04835376]25 participants (Actual)Interventional2021-05-01Completed
Effectiveness of Respiratory Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease[NCT02125747]35 participants (Actual)Interventional2011-12-31Completed
[NCT00000565]Phase 30 participants Interventional1976-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hospital Length of Stay

an average of 10 days (NCT00717873)
Timeframe: Admission to Discharge

Interventiondays (Mean)
HFCWO Arm2.95
CPT Arm5.45

Reviews

43 reviews available for guaifenesin and Lung Diseases, Obstructive

ArticleYear
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2020, 04-30, Volume: 4

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Disease Prog

2020
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2020, 04-30, Volume: 4

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Disease Prog

2020
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2020, 04-30, Volume: 4

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Disease Prog

2020
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2020, 04-30, Volume: 4

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Disease Prog

2020
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2017, 05-04, Volume: 5

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Disease Prog

2017
Emerging Concepts and Therapies for Mucoobstructive Lung Disease.
    Annals of the American Thoracic Society, 2018, Volume: 15, Issue:Suppl 3

    Topics: Chloride Channel Agonists; Expectorants; Humans; Lung Diseases, Obstructive; Mucus

2018
Fungi in Mucoobstructive Airway Diseases.
    Annals of the American Thoracic Society, 2018, Volume: 15, Issue:Suppl 3

    Topics: Antifungal Agents; Fibrinogen; Humans; Lung Diseases, Obstructive; Mucus; Mycoses; Peptide Hydrolase

2018
Muco-Obstructive Lung Diseases.
    The New England journal of medicine, 2019, 05-16, Volume: 380, Issue:20

    Topics: Bronchiectasis; Cilia; Cystic Fibrosis; Disease Progression; Expectorants; Humans; Lung Diseases, Ob

2019
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2014, Jul-20, Issue:7

    Topics: Adolescent; Adult; Breathing Exercises; Chest Wall Oscillation; Child; Cystic Fibrosis; Forced Expir

2014
Oscillating devices for airway clearance in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Adolescent; Adult; Breathing Exercises; Child; Cystic Fibrosis; Forced Expiratory Volume; Humans; Lu

2009
Respiratory issues in the management of children with neuromuscular disease.
    Respiratory care, 2006, Volume: 51, Issue:8

    Topics: Child; Cough; Drainage; Humans; Infant; Lung Diseases, Obstructive; Mucus; Neuromuscular Diseases; P

2006
Mucin overproduction in chronic inflammatory lung disease.
    Canadian respiratory journal, 2006, Volume: 13, Issue:6

    Topics: Chronic Disease; Cytokines; Humans; Leukocyte Elastase; Lung Diseases, Obstructive; Mucins; Mucus

2006
Forced expiratory technique, directed cough, and autogenic drainage.
    Respiratory care, 2007, Volume: 52, Issue:9

    Topics: Breathing Exercises; Bronchi; Cough; Drainage, Postural; Humans; Lung Diseases, Obstructive; Mucocil

2007
High-frequency assisted airway clearance.
    Respiratory care, 2007, Volume: 52, Issue:9

    Topics: Bronchi; Chest Wall Oscillation; Drainage, Postural; Humans; Lung Diseases, Obstructive; Mucus; Phys

2007
Emerging mucus regulating drugs in inflammatory and allergic lung disease.
    Inflammation & allergy drug targets, 2008, Volume: 7, Issue:1

    Topics: Asthma; Cystic Fibrosis; Humans; Lung Diseases, Obstructive; Mucins; Mucus; Respiratory System Agent

2008
Human respiratory mucus.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:3

    Topics: Adrenal Cortex Hormones; Atropine; Bronchi; Glycoproteins; Humans; Lung Diseases, Obstructive; Mucou

1984
Clearance of particles from the human tracheobronchial tree.
    Clinical science (London, England : 1979), 1980, Volume: 59, Issue:2

    Topics: Bronchi; Cilia; Cough; Humans; Lung Diseases, Obstructive; Mucus; Respiration; Sleep; Trachea

1980
Virulence factors in the colonization and persistence of bacteria in the airways.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:6

    Topics: Bacterial Infections; Humans; Lung Diseases, Obstructive; Mucus; Respiratory Tract Infections; Time

1995
[Chronic obstructive pulmonary disease (COPD)].
    Kokyu to junkan. Respiration & circulation, 1993, Volume: 41, Issue:1

    Topics: Adrenergic beta-Agonists; Airway Resistance; Animals; Atropine; Bronchography; Humans; Lung; Lung Di

1993
Mucus transport mechanisms in relation to the effect of high frequency chest compression (HFCC) on mucus clearance.
    Pediatric pulmonology, 1994, Volume: 17, Issue:2

    Topics: Clinical Trials as Topic; Cystic Fibrosis; Drainage, Postural; Gravity Suits; Humans; Lung Diseases,

1994
[Expectoration--an underestimated symptom?].
    Ugeskrift for laeger, 1993, Sep-27, Volume: 155, Issue:39

    Topics: Bronchoalveolar Lavage Fluid; Humans; Lung; Lung Diseases, Obstructive; Lung Neoplasms; Mucus; Progn

1993
[Bronchial mucus modifiers, antioxidants and antiproteases].
    Revue des maladies respiratoires, 1993, Volume: 10, Issue:2

    Topics: Antioxidants; Expectorants; Humans; Lung Diseases, Obstructive; Mucociliary Clearance; Mucus; Protea

1993
Noninvasive clearance of airway secretions.
    Respiratory care clinics of North America, 1996, Volume: 2, Issue:2

    Topics: Drainage; Humans; Lung Diseases, Obstructive; Mucus; Physical Therapy Modalities; Respiration, Artif

1996
Cystic fibrosis. An overview.
    Radiologic clinics of North America, 1998, Volume: 36, Issue:1

    Topics: Bile Duct Diseases; Bronchiectasis; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Humans; Lung

1998
Mucoactive drugs in the management of chronic obstructive pulmonary disease.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1998, Volume: 53, Issue:6

    Topics: Animals; Bronchitis; Chronic Disease; Clinical Trials as Topic; Expectorants; Humans; Lung Diseases,

1998
The pathogenesis of chronic obstructive pulmonary disease.
    The American journal of the medical sciences, 1999, Volume: 318, Issue:2

    Topics: Bronchi; Bronchial Hyperreactivity; Dust; Endopeptidases; Humans; Lung Diseases, Obstructive; Mucus;

1999
[Roles of airway inflammation in chronic airflow obstruction].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:9

    Topics: Elasticity; Humans; Inflammation; Leukocytes; Lung; Lung Diseases; Lung Diseases, Obstructive; Macro

1999
Bacterial infection and the pathogenesis of COPD.
    Chest, 2000, Volume: 117, Issue:5 Suppl 1

    Topics: Bacteria; Disease Progression; Humans; Immunity, Cellular; Lung Diseases, Obstructive; Mucociliary C

2000
Role of neutrophil elastase in hypersecretion during COPD exacerbations, and proposed therapies.
    Chest, 2000, Volume: 117, Issue:5 Suppl 2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cell Movement; Chemotactic Factors; Go

2000
Mucus pathophysiology in COPD: differences to asthma, and pharmacotherapy.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2000, Volume: 55, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Enzyme Inhibitors; Expectorants; Humans; Lung Disea

2000
Mucus hypersecretion in chronic obstructive pulmonary disease.
    Novartis Foundation symposium, 2001, Volume: 234

    Topics: Humans; Lung Diseases, Obstructive; Mucins; Mucus

2001
Alternative mechanisms for long-acting beta(2)-adrenergic agonists in COPD.
    Chest, 2001, Volume: 120, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Ethanolamines; Formoterol Fumarate; Huma

2001
Remodeling in response to infection and injury. Airway inflammation and hypersecretion of mucus in smoking subjects with chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2001, Nov-15, Volume: 164, Issue:10 Pt 2

    Topics: Biopsy; Bronchitis; CD4-CD8 Ratio; Chronic Disease; Goblet Cells; Humans; Hyperplasia; Inflammation;

2001
The lung: structure, function and disease. Miscellany.
    Monographs in pathology, 1978, Volume: 19

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Carcinoma, Adenoid Cystic; Chronic Disease; Coal Minin

1978
Respiratory mucociliary clearance in the horse in health and disease, and its pharmaceutical modification.
    The Veterinary record, 1992, Sep-12, Volume: 131, Issue:11

    Topics: Animals; Horse Diseases; Horses; Lung Diseases; Lung Diseases, Obstructive; Mucociliary Clearance; M

1992
The lung mucosa: a critical environmental battleground.
    The American journal of medicine, 1991, Oct-21, Volume: 91, Issue:4A

    Topics: Adult; Air Pollutants; Asthma; Child; Humans; Lung; Lung Diseases, Obstructive; Mucociliary Clearanc

1991
Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1

    Topics: Asthma; Bronchi; Humans; Lung; Lung Diseases, Obstructive; Microscopy, Electron; Microscopy, Electro

1991
The role of mucus in chronic obstructive pulmonary disease.
    Chest, 1990, Volume: 97, Issue:2 Suppl

    Topics: Bronchitis; Humans; Lung Diseases, Obstructive; Mucociliary Clearance; Mucus; Smoking

1990
The role of chronic bronchitis in the pathogenesis of chronic obstructive pulmonary disease.
    Seminars in respiratory infections, 1988, Volume: 3, Issue:1

    Topics: Animals; Bronchitis; Chronic Disease; Humans; Lung Diseases, Obstructive; Mucus; Respiratory Tract I

1988
Theophylline and mucociliary clearance.
    Chest, 1987, Volume: 92, Issue:1 Suppl

    Topics: Aminophylline; Animals; Asthma; Bronchitis; Cilia; Clinical Trials as Topic; Dogs; Humans; Lung Dise

1987
[Mucociliary transport in obstructive lung disease].
    Harefuah, 1987, Apr-01, Volume: 112, Issue:7

    Topics: Biological Transport; Cilia; Humans; Lung Diseases, Obstructive; Mucus

1987
Epidemiology of bronchial hypersecretion: recent studies.
    European journal of respiratory diseases. Supplement, 1987, Volume: 153

    Topics: Airway Obstruction; Anti-Bacterial Agents; Asthma; Bronchial Diseases; Bronchitis; Epidemiologic Met

1987
Ciliary function in health and disease.
    British journal of diseases of the chest, 1985, Volume: 79, Issue:1

    Topics: Bronchitis; Cilia; Ciliary Motility Disorders; Cystic Fibrosis; Humans; Lung; Lung Diseases, Obstruc

1985
Hereditary aspects of COPD.
    Postgraduate medicine, 1973, Volume: 54, Issue:3

    Topics: Adult; Alpha-Globulins; Cystic Fibrosis; Cytoplasm; Female; Heterozygote; Humans; Lung; Lung Disease

1973
Small airways disease.
    Human pathology, 1973, Volume: 4, Issue:2

    Topics: Airway Obstruction; Airway Resistance; Animals; Bronchitis; Chronic Disease; Dogs; Humans; Inflammat

1973
Sites and mechanisms of airway obstruction in COPD.
    Postgraduate medicine, 1973, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Airway Obstruction; Airway Resistance; Bronchi; Child; Child,

1973

Trials

16 trials available for guaifenesin and Lung Diseases, Obstructive

ArticleYear
Clinical evaluation of terbutaline and glyceryl guaiacolate in chronic obstructive lung disease.
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:3

    Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Female; Guaifenesin; Hum

1976
[Defence capacities of the respiratory tract].
    Schweizerische medizinische Wochenschrift, 1975, Aug-02, Volume: 105, Issue:31

    Topics: Acetylcysteine; Aerosols; Drug Combinations; Gases; Guaifenesin; Humans; Isoproterenol; Lung Disease

1975
Nanoparticulate CpG immunotherapy in RAO-affected horses: phase I and IIa study.
    Journal of veterinary internal medicine, 2015, Volume: 29, Issue:1

    Topics: Animals; Auscultation; Female; Horse Diseases; Horses; Lung; Lung Diseases, Obstructive; Male; Mucus

2015
Effects of a beta adrenergic drug and a secretolytic agent on regional mucociliary clearance in patients with COLD.
    Chest, 1981, Volume: 80, Issue:6 Suppl

    Topics: Albumins; Ambroxol; Bromhexine; Cilia; Clenbuterol; Clinical Trials as Topic; Double-Blind Method; E

1981
The effect of oral aminophylline on lung mucociliary clearance in man.
    Chest, 1981, Volume: 80, Issue:6 Suppl

    Topics: Administration, Oral; Adult; Aminophylline; Cilia; Clinical Trials as Topic; Delayed-Action Preparat

1981
Clinical evaluation of oscillating positive expiratory pressure for enhancing expectoration in diseases other than cystic fibrosis.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1995, Volume: 50, Issue:4

    Topics: Aged; Bronchiectasis; Bronchitis; Cough; Cystic Fibrosis; Drainage, Postural; Female; Humans; Lung D

1995
Regional mucus transport following unproductive cough and forced expiration technique in patients with airways obstruction.
    Chest, 1994, Volume: 105, Issue:5

    Topics: Cough; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructive; Male; Mucociliary

1994
The effects of a community-based pulmonary rehabilitation programme on exercise tolerance and quality of life: a randomized controlled trial.
    The European respiratory journal, 1997, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Breathing Exercises; Combined Modality Therapy; Community Health Se

1997
[Corticosteroids].
    Revue des maladies respiratoires, 1998, Volume: 15 Suppl 2

    Topics: Administration, Inhalation; Beclomethasone; Bronchitis; Bronchodilator Agents; Female; Glucocorticoi

1998
The effect of inhalation therapy on ventilatory function and expectoration.
    Chest, 1978, Volume: 73, Issue:6

    Topics: Aerosols; Bronchi; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Intermittent Posit

1978
Effects of S-carboxymethylcysteine on tracheal mucus velocity.
    Chest, 1978, Volume: 74, Issue:6

    Topics: Adult; Bronchitis; Carbocysteine; Chronic Disease; Clinical Trials as Topic; Cysteine; Female; Human

1978
Action of tulobuterol and fenoterol on the mucociliary clearance.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Cilia; Female; Fenoterol; Hemodynamics; Hu

1987
Evaluation of the activity of the carbocysteine-sobrerol combination on mucus spinnability.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:1

    Topics: Carbocysteine; Clinical Trials as Topic; Cysteine; Double-Blind Method; Drug Combinations; Expectora

1988
Theophylline and mucociliary clearance.
    Chest, 1987, Volume: 92, Issue:1 Suppl

    Topics: Aminophylline; Animals; Asthma; Bronchitis; Cilia; Clinical Trials as Topic; Dogs; Humans; Lung Dise

1987
Influence of tasuldine and acetylcysteine on mucociliary clearance in patients with chronic airways obstruction.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Cilia; Expectorants; Humans; Lung; Lung Diseases, Obstructive; Middle A

1986
A new mucolytic, bromhexine ("bisolvon"). A double-blind study.
    The Medical journal of Australia, 1971, May-01, Volume: 1, Issue:18

    Topics: Aniline Compounds; Asthma; Bronchiectasis; Bronchitis; Clinical Trials as Topic; Expectorants; Femal

1971

Other Studies

95 other studies available for guaifenesin and Lung Diseases, Obstructive

ArticleYear
Chronic obstructive pulmonary disease.
    Comprehensive therapy, 1975, Volume: 1, Issue:8

    Topics: Acetylcysteine; Aerosols; Anti-Bacterial Agents; Bronchodilator Agents; Chronic Disease; Expectorant

1975
Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier.
    Thorax, 2022, Volume: 77, Issue:8

    Topics: Animals; DNA; Genetic Therapy; Humans; Lung; Lung Diseases, Obstructive; Mice; Mucus; Nanoparticles

2022
Muco-Obstructive Lung Diseases.
    The New England journal of medicine, 2019, 09-05, Volume: 381, Issue:10

    Topics: Humans; Lung; Lung Diseases, Obstructive; Mucus; Pulmonary Artery

2019
Muco-Obstructive Lung Diseases.
    The New England journal of medicine, 2019, 09-05, Volume: 381, Issue:10

    Topics: Humans; Lung; Lung Diseases, Obstructive; Mucus; Pulmonary Artery

2019
Muco-Obstructive Lung Diseases. Reply.
    The New England journal of medicine, 2019, 09-05, Volume: 381, Issue:10

    Topics: Humans; Lung Diseases, Obstructive; Mucus

2019
Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.
    American journal of respiratory cell and molecular biology, 2020, Volume: 62, Issue:3

    Topics: Aging; Animals; Antibodies; Apoptosis; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Cytokine

2020
Intravital microscopic optical coherence tomography imaging to assess mucus-mobilizing interventions for muco-obstructive lung disease in mice.
    American journal of physiology. Lung cellular and molecular physiology, 2020, 03-01, Volume: 318, Issue:3

    Topics: Animals; Disease Models, Animal; Epithelial Sodium Channels; Humans; Intravital Microscopy; Lung Dis

2020
Quantification of muco-obstructive lung disease variability in mice via laboratory X-ray velocimetry.
    Scientific reports, 2020, 07-02, Volume: 10, Issue:1

    Topics: Animals; Heart; Lung Diseases, Obstructive; Mice; Mucociliary Clearance; Mucus; X-Ray Microtomograph

2020
Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 08-01, Volume: 199, Issue:3

    Topics: Animals; Animals, Newborn; Bacterial Infections; Bacterial Load; Cell Movement; Cystic Fibrosis; Dis

2017
Dawn of a New Era in the Diagnosis and Treatment of Airway Mucus Dysfunction.
    American journal of respiratory and critical care medicine, 2019, 01-15, Volume: 199, Issue:2

    Topics: Expectorants; Humans; Lung Diseases, Obstructive; Mucus; Respiratory System

2019
Owner-reported coughing and nasal discharge are associated with clinical findings, arterial oxygen tension, mucus score and bronchoprovocation in horses with recurrent airway obstruction in a field setting.
    Equine veterinary journal, 2015, Volume: 47, Issue:3

    Topics: Animals; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Cough; Cross-Sectional Studies; Histamine; H

2015
On the Pathogenesis of Acute Exacerbations of Mucoobstructive Lung Diseases.
    Annals of the American Thoracic Society, 2015, Volume: 12 Suppl 2

    Topics: Animals; Disease Models, Animal; Disease Progression; Humans; Lung; Lung Diseases, Obstructive; Mice

2015
Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro.
    Journal of pharmacological sciences, 2010, Volume: 113, Issue:1

    Topics: Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regula

2010
Plugging (publicising) to prevent mucous plugging.
    The European respiratory journal, 2010, Volume: 36, Issue:6

    Topics: Humans; Lung Diseases, Obstructive; Mucus

2010
Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.
    Physiological genomics, 2012, Apr-15, Volume: 44, Issue:8

    Topics: Airway Obstruction; Animals; Disease Models, Animal; Epithelial Sodium Channels; Lung Diseases, Obst

2012
Mucus in chronic airway diseases: sorting out the sticky details.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:2

    Topics: Animals; Disease Models, Animal; Epithelial Cells; ErbB Receptors; Humans; Interleukin-13; Lung Dise

2006
Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.
    The Journal of infectious diseases, 2006, Jun-15, Volume: 193, Issue:12

    Topics: Animals; Disease Models, Animal; Histocytochemistry; Lung; Lung Diseases, Obstructive; Metapneumovir

2006
Mucus hypersecretion, airways obstruction, and mortality from chronic lung disease.
    Lancet (London, England), 1984, Feb-11, Volume: 1, Issue:8372

    Topics: Airway Obstruction; Humans; Lung Diseases, Obstructive; Mucus; Respiratory Function Tests; Smoking

1984
Autonomic nervous system abnormalities in cystic fibrosis.
    Journal of chronic diseases, 1983, Volume: 36, Issue:3

    Topics: Animals; Autonomic Nervous System; Cardiovascular System; Cystic Fibrosis; Dogs; Eccrine Glands; Hum

1983
Evaluation of the bronchi with CT.
    Seminars in roentgenology, 1984, Volume: 19, Issue:3

    Topics: Bronchi; Bronchial Diseases; Bronchial Neoplasms; Bronchiectasis; Bronchography; Bronchopneumonia; B

1984
Influence of rheological properties of human bronchial secretions on the ciliary beat frequency.
    Biorheology, 1984, Volume: 21, Issue:1-2

    Topics: Animals; Anura; Bronchi; Cilia; Humans; Lung Diseases, Obstructive; Middle Aged; Mucus; Rheology; Sp

1984
[Elastase and elastase inhibitors in bronchial mucus in chronic airway obstruction with reference to therapy].
    Praxis und Klinik der Pneumologie, 1983, Volume: 37 Suppl 1

    Topics: Bronchi; Humans; Lung Diseases, Obstructive; Mucus; Pancreatic Elastase

1983
A new viscoelastometer for studying the rheological properties of bronchial mucus in clinical practice.
    Biorheology. Supplement : the official journal of the International Society of Biorheology, 1984, Volume: 1

    Topics: Bronchi; Elasticity; Equipment Design; Humans; Lung Diseases, Obstructive; Mucus; Rheology; Viscosit

1984
The relevance in adults of air-flow obstruction, but not of mucus hypersecretion, to mortality from chronic lung disease. Results from 20 years of prospective observation.
    The American review of respiratory disease, 1983, Volume: 128, Issue:3

    Topics: Adult; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Male; Middle Ag

1983
Regional mucociliary removal of inhaled particles in smokers with small airways disease.
    Respiration; international review of thoracic diseases, 1983, Volume: 44, Issue:5

    Topics: Adult; Aerosols; Airway Obstruction; Cilia; Humans; Lung Diseases, Obstructive; Microspheres; Middle

1983
Influenza hemagglutination inhibiting activity in respiratory mucus from horses with chronic obstructive pulmonary disorders (heaves syndrome).
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1983, Volume: 47, Issue:3

    Topics: Animals; Antibodies, Viral; Hemagglutination Inhibition Tests; Horse Diseases; Horses; Influenza A v

1983
Could a defect in host-immunity be the cause of respiratory infections?
    Clinics in chest medicine, 1981, Volume: 2, Issue:1

    Topics: Adult; Agammaglobulinemia; Aged; Child; Cilia; Cystic Fibrosis; Female; Humans; Lung Diseases, Obstr

1981
Methods of evaluation of expectorants and mucolytics--measurement of lung function.
    European journal of respiratory diseases. Supplement, 1980, Volume: 110

    Topics: Expectorants; Humans; Lung Diseases, Obstructive; Mucus; Pulmonary Ventilation

1980
Mucociliary transport and cough as clearance mechanisms in obstructive lung disease.
    European journal of respiratory diseases. Supplement, 1980, Volume: 111

    Topics: Bronchi; Chronic Disease; Cilia; Cough; Humans; Lung Diseases, Obstructive; Mucus; Trachea

1980
Mucus in chronic obstructive airway diseases.
    European journal of respiratory diseases. Supplement, 1980, Volume: 111

    Topics: Bronchi; Elasticity; Histamine; Humans; Leukocytes; Lung Diseases, Obstructive; Mucus

1980
Chemical composition of pathological human tracheobronchial mucus collected by fiberoptic bronchoscopy.
    Advances in experimental medicine and biology, 1982, Volume: 144

    Topics: Adult; Bronchi; Bronchitis; Bronchoscopy; Fiber Optic Technology; Humans; Lung Diseases; Lung Diseas

1982
The role of mucociliary transport in the pathogenesis of chronic obstructive pulmonary disease.
    Advances in experimental medicine and biology, 1982, Volume: 144

    Topics: Biological Transport; Bronchi; Cilia; Humans; Lung Diseases, Obstructive; Mucus; Trachea

1982
The importance of lysozyme for the viscosity of sputum from patients with chronic obstructive lung disease.
    Scandinavian journal of clinical and laboratory investigation, 1980, Volume: 40, Issue:8

    Topics: Chlorides; Humans; Lithium; Lung Diseases, Obstructive; Mucus; Muramidase; Sputum; Viscosity

1980
[Regional mucociliary clearance in patients with small-airways disease (author's transl)].
    Praxis und Klinik der Pneumologie, 1981, Volume: 35, Issue:7

    Topics: Adult; Aerosols; Cilia; Humans; Lung Diseases, Obstructive; Microspheres; Mucus; Respiratory Functio

1981
Impaired mucociliary transport as a pathogenetic factor in obstructive pulmonary diseases.
    Chest, 1980, Volume: 77, Issue:2 Suppl

    Topics: Adult; Bronchitis; Cilia; Female; Humans; Lung Diseases, Obstructive; Male; Mucus; Respiratory Syste

1980
Chronic mucus hypersecretion in COPD and death from pulmonary infection.
    The European respiratory journal, 1995, Volume: 8, Issue:8

    Topics: Cause of Death; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Respiratory Me

1995
Chronic mucus hypersecretion in COPD and death from pulmonary infection.
    The European respiratory journal, 1995, Volume: 8, Issue:8

    Topics: Cause of Death; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Respiratory Me

1995
Chronic mucus hypersecretion in COPD and death from pulmonary infection.
    The European respiratory journal, 1995, Volume: 8, Issue:8

    Topics: Cause of Death; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Respiratory Me

1995
Chronic mucus hypersecretion in COPD and death from pulmonary infection.
    The European respiratory journal, 1995, Volume: 8, Issue:8

    Topics: Cause of Death; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Respiratory Me

1995
The pathophysiological role of mucus production in inflammatory airway diseases.
    Respiratory medicine, 1995, Volume: 89, Issue:5

    Topics: Asthma; Bronchitis; Cystic Fibrosis; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; M

1995
Effect of enhanced supramaximal flows on cough clearance.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:4

    Topics: Adult; Aged; Computers; Cough; Cystic Fibrosis; Female; Humans; Lung; Lung Diseases, Obstructive; Ma

1994
Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:9

    Topics: Aerosols; Animals; Disease Models, Animal; Epithelium; Glycoproteins; Hyperplasia; Hypertrophy; Lung

1994
Viscous airflow through a rigid tube with a compliant lining: a simple model for the air-mucus interaction in pulmonary airways.
    Journal of biomechanical engineering, 1993, Volume: 115, Issue:3

    Topics: Air; Airway Resistance; Animals; Compliance; Elasticity; Evaluation Studies as Topic; Humans; Linear

1993
Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:5

    Topics: Adult; Age Factors; Aged; Denmark; Female; Follow-Up Studies; Forced Expiratory Volume; Hospitalizat

1996
Mucoid impaction of the trachea simulating a tumor: a case report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1996, Volume: 58, Issue:2

    Topics: Aged; Diagnosis, Differential; Female; Humans; Lung Diseases, Obstructive; Mucus; Tracheal Diseases;

1996
Ulcerous tracheitis and mucus ball formation: a nearly fatal complication of a transtracheal oxygen catheter.
    Respiration; international review of thoracic diseases, 1996, Volume: 63, Issue:6

    Topics: Aged; Catheterization; Humans; Lung Diseases, Obstructive; Male; Mucus; Oxygen Inhalation Therapy; T

1996
[Chronic expectoration and risk of death in chronic obstructive lung disease].
    Ugeskrift for laeger, 1996, Nov-04, Volume: 158, Issue:45

    Topics: Adult; Aged; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Longitudinal Studies; Lung

1996
[Dangerous complication of transtracheal oxygen therapy with the SCOOP(R) system].
    Pneumologie (Stuttgart, Germany), 1996, Volume: 50, Issue:10

    Topics: Aged; Airway Obstruction; Bronchoscopy; Catheters, Indwelling; Equipment Failure; Female; Humans; In

1996
Dual D2-receptor and beta2-adrenoceptor agonists for the treatment of airway diseases. 1. Discovery and biological evaluation of some 7-(2-aminoethyl)-4-hydroxybenzothiazol-2(3H)-one analogues.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Anti-Asthmatic Agents; Bronc

1998
Factors associated with increased risk of exacerbation and hospital admission in a cohort of ambulatory COPD patients: a multiple logistic regression analysis. The EOLO Study Group.
    Respiration; international review of thoracic diseases, 2000, Volume: 67, Issue:5

    Topics: Age Factors; Aged; Ambulatory Care; Comorbidity; Cross-Sectional Studies; Female; Forced Expiratory

2000
How to predict exacerbations and hospital admissions in stable COPD outpatients.
    Respiration; international review of thoracic diseases, 2000, Volume: 67, Issue:5

    Topics: Age Factors; Comorbidity; Forced Expiratory Volume; Hospitalization; Humans; Logistic Models; Lung D

2000
Effect of respiratory drugs on mucociliary clearance.
    Chest, 1978, Volume: 73, Issue:6 Suppl

    Topics: Adrenergic beta-Agonists; Albuterol; Aminophylline; Animals; Beclomethasone; Cats; Chlorofluorocarbo

1978
Mucus antibodies in pulmonary tuberculosis and chronic obstructive lung disease.
    Lancet (London, England), 1976, Oct-16, Volume: 2, Issue:7990

    Topics: Animals; Antigen-Antibody Reactions; Asthma; Autoantibodies; Bronchitis; Fluorescent Antibody Techni

1976
[The "IgA secretory component complex" in bronchial mucus in patients with chronic obstructive lung disease under different therapy (author's transl)].
    Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:2

    Topics: Adult; Age Factors; Anti-Bacterial Agents; Bronchi; gamma-Globulins; Glucocorticoids; Humans; Immuno

1979
Bronchial mucus in obstructive lung disease.
    Scandinavian journal of respiratory diseases. Supplementum, 1979, Volume: 103

    Topics: Blood Proteins; Body Water; Bronchi; Electrolytes; Glycoproteins; Humans; Lipids; Lung Diseases, Obs

1979
[Inter-alpha-trypsin inhibitor in serum and bronchial mucus inhibitor in sputum in chronic airway obstruction (author's transl)].
    Respiration; international review of thoracic diseases, 1978, Volume: 36, Issue:1

    Topics: Airway Obstruction; alpha 1-Antitrypsin; Bronchi; Chronic Disease; Humans; Lung Diseases, Obstructiv

1978
Relationship of smoking history and pulmonary function tests to tracheal mucous velocity in nonsmokers, young smokers, ex-smokers, and patients with chronic bronchitis.
    The American review of respiratory disease, 1978, Volume: 117, Issue:2

    Topics: Adult; Age Factors; Aged; Bronchitis; Chronic Disease; Cough; Female; Humans; Lung Diseases, Obstruc

1978
Microliths in sputum specimens and their relationship to pulmonary alveolar microlithiasis.
    American journal of clinical pathology, 1978, Volume: 69, Issue:5

    Topics: Calcium; Calculi; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Pulmonary Al

1978
[Clearance of Hydrast from airways and its stimulation by terbutaline (author's transl)].
    Praxis der Pneumologie, 1976, Volume: 30, Issue:6

    Topics: Adult; Bronchography; Cilia; Female; Humans; Iodopyridones; Lung Diseases, Obstructive; Mucus; Terbu

1976
[Obturation of the bronchi by mucus as a cause of postoperative respiratory insufficiency].
    Klinicheskaia khirurgiia, 1976, Issue:4

    Topics: Adolescent; Adult; Bronchi; Female; Humans; Lung Diseases, Obstructive; Male; Mucus; Postoperative C

1976
[The small airways obstruction: an assay of structure-function correlation].
    Le Poumon et le coeur, 1975, Volume: 31, Issue:5

    Topics: Bronchi; Emphysema; Epithelium; Humans; Inflammation; Lung Diseases, Obstructive; Mucus; Respiratory

1975
Contribution of morphometry, bronchial casts and electron microscopy to study of airway obstruction in chronic obstructive lung disease.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:2

    Topics: Airway Obstruction; Bronchi; Humans; Lung Diseases, Obstructive; Mucus

1976
Phospholipid composition and surface-active properties of tracheobronchial secretions from patients with cystic fibrosis and chronic obstructive pulmonary diseases.
    Pediatric pulmonology, 1992, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchiectasis; Child; Cystic Fibrosis; Humans; Lung Dis

1992
The International Clinical Respiratory Group. Report of the first meeting.
    Chest, 1991, Volume: 100, Issue:2

    Topics: Congresses as Topic; Europe; Humans; Lung; Lung Diseases, Obstructive; Mucus; North America; Oxygen

1991
[Various types of tobacco smoking and development of chronic obstructive pulmonary disease. Results from the Osterbro study].
    Ugeskrift for laeger, 1991, Sep-23, Volume: 153, Issue:39

    Topics: Adult; Aged; Denmark; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Mi

1991
Relevance of airflow obstruction and mucus hypersecretion to mortality.
    Respiratory medicine, 1991, Volume: 85, Issue:1

    Topics: Airway Obstruction; Cause of Death; Coronary Disease; Follow-Up Studies; Forced Expiratory Volume; G

1991
[Kinetics of mucus].
    Revue medicale de Liege, 1990, Jan-01, Volume: 45, Issue:1

    Topics: Acetylcysteine; Antitussive Agents; Bromhexine; Cough; Expectorants; Humans; Lung Diseases, Obstruct

1990
Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes.
    Thorax, 1990, Volume: 45, Issue:8

    Topics: Adult; Aged; Cause of Death; Denmark; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases,

1990
The value of mucus hypersecretion as a predictor of mortality and hospitalization. An 11-year register based follow-up study of a random population sample of 876 men.
    Respiratory medicine, 1989, Volume: 83, Issue:3

    Topics: Aged; Follow-Up Studies; Forced Expiratory Volume; Forecasting; Hospitalization; Humans; Lung Diseas

1989
[Clinical aspects of peripheral airway diseases in chronic obstructive pulmonary disease].
    Nihon Kyobu Shikkan Gakkai zasshi, 1989, Volume: 27, Issue:5

    Topics: Animals; Bronchial Diseases; Bronchitis; Chronic Disease; Dogs; Humans; Lung Diseases, Obstructive;

1989
Morphometric analysis of intraluminal mucus in airways in chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1989, Volume: 140, Issue:2

    Topics: Aged; Aged, 80 and over; Bronchitis; Chronic Disease; Female; Humans; In Vitro Techniques; Lung Dise

1989
Respiratory symptoms and FEV1 as predictors of hospitalization and medication in the following 12 years due to respiratory disease.
    The European respiratory journal, 1989, Volume: 2, Issue:8

    Topics: Aged; Cough; Denmark; Dyspnea; Follow-Up Studies; Forced Expiratory Volume; Hospitalization; Humans;

1989
Physiologic implications of the autonomic aberrations in cystic fibrosis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:4

    Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Autonomic Nervous System; Bronchi; Bronchial P

1986
[Clinically relevant mechanisms of mucus gland hypertrophy].
    Praxis und Klinik der Pneumologie, 1988, Volume: 42, Issue:7

    Topics: Animals; Autoradiography; Ferrets; Humans; Hypertrophy; Lung Diseases, Obstructive; Mucous Membrane;

1988
Monoclonal antibodies directed against human airway secretions. Localization and characterization of antigens.
    The American journal of pathology, 1988, Volume: 131, Issue:2

    Topics: Antibodies, Monoclonal; Antigens; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme-L

1988
Rheological evaluation of mucus and its clinical implication.
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Humans; Lung; Lung Diseases, Obstructive; Mucus; Rheology

1986
Mucociliary clearance in obstructive lung diseases. Correlations to the immotile cilia syndrome.
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Adult; Aged; Bronchi; Cilia; Ciliary Motility Disorders; Female; Humans; Lung Diseases, Obstructive;

1986
[Airway dynamics analyzed with radioaerosol clearance].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:1

    Topics: Aerosols; Animals; Biological Transport; Bronchi; Cilia; Humans; Lung; Lung Diseases, Obstructive; M

1987
[Pathophysiology of chronic bronchitis].
    Wiener medizinische Wochenschrift (1946), 1986, Dec-31, Volume: 136, Issue:23-24

    Topics: Airway Resistance; Asthma; Bronchitis; Chronic Disease; Humans; Lung Diseases, Obstructive; Mucus; M

1986
[Diagnosis, differential diagnosis and therapy of chronic bronchitis].
    Wiener medizinische Wochenschrift (1946), 1986, Dec-31, Volume: 136, Issue:23-24

    Topics: Anti-Bacterial Agents; Bronchitis; Chronic Disease; Diagnosis, Differential; Humans; Lung Diseases,

1986
[Diagnosis of disorders in the local pulmonary defense system in patients with nonspecific diseases of the lungs].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:3

    Topics: Algorithms; Bronchi; Cilia; Diagnosis, Differential; Humans; Lung Diseases, Obstructive; Macrophages

1987
[Adrenergic receptors of the bronchoalveolar system in the obstructive syndrome].
    Revue de pneumologie clinique, 1987, Volume: 43, Issue:2

    Topics: Bronchi; Bronchial Spasm; Cilia; Humans; Lung Diseases, Obstructive; Mucus; Muscle Contraction; Pulm

1987
[Effect of coughing on regional mucociliary clearance in patients with chronic obstructive airway diseases].
    Praxis und Klinik der Pneumologie, 1986, Volume: 40, Issue:5

    Topics: Bronchi; Cilia; Ciliary Motility Disorders; Cough; Epithelium; Humans; Lung Diseases, Obstructive; M

1986
Effect of manual percussion on tracheobronchial clearance in patients with chronic airflow obstruction and excessive tracheobronchial secretion.
    Thorax, 1986, Volume: 41, Issue:6

    Topics: Aged; Bronchi; Drainage; Humans; Lung; Lung Diseases, Obstructive; Male; Middle Aged; Mucus; Percuss

1986
Inhibitor activity against elastolytic enzymes in the bronchial area. A contribution to the pathogenesis of chronic airway obstruction.
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1985, Volume: 165, Issue:1

    Topics: Anti-Bacterial Agents; Bronchi; Cortisone; Humans; Lung Diseases, Obstructive; Mucus; Muramidase; Ne

1985
Mucociliary clearance and airways obstruction in smokers, ex-smokers and normal subjects who never smoked.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Adult; Age Factors; Aged; Biological Transport; Bronchitis; Cilia; Erythrocytes; Female; Humans; Lun

1985
The National Institutes of Health Intermittent Positive-Pressure Breathing trial: pathology studies. I. Interrelationship between morphologic lesions.
    The American review of respiratory disease, 1985, Volume: 132, Issue:5

    Topics: Adult; Age Factors; Aged; Bronchi; Exocrine Glands; Humans; Intermittent Positive-Pressure Breathing

1985
The problem of mucus plugging in children with asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1985, Volume: 22, Issue:3

    Topics: Asthma; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Lung; Lung Diseases, Obs

1985
Therapy of obstructive bronchial diseases: the physicochemical approach.
    The Journal of asthma research, 1971, Volume: 8, Issue:4

    Topics: Alkalies; Anti-Infective Agents; Bronchi; Bronchial Diseases; Bronchodilator Agents; Chemical Phenom

1971
[Free and combined protease inhibitors in bronchial mucus in patients with extended chronic obstructive airway diseases (author's transl)].
    Pneumonologie. Pneumonology, 1974, Volume: 150, Issue:2-4

    Topics: Aged; Bronchi; Chronic Disease; Humans; Lung Diseases, Obstructive; Mucus; Protease Inhibitors; Sput

1974
Conference on the scientific basis of respiratory therapy. Aerosol therapy. Introduction.
    The American review of respiratory disease, 1974, Volume: 110, Issue:6 Pt 2

    Topics: Adrenal Cortex Hormones; Aerosols; Asthma; Bronchi; Bronchodilator Agents; Chronic Disease; Expector

1974
Colonization of the respiratory tract and postoperative pulmonary infections. The value of intraoperative endotracheal aspirate cultures.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 107, Issue:2

    Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Endotracheal; Anti-Bacterial Agents; Bacteria; Bronchi

1973
Tracheal mucous velocity in normal man and patients with obstructive lung disease: effects of terbutaline.
    The American review of respiratory disease, 1974, Volume: 109, Issue:4

    Topics: Adult; Aged; Bronchoscopy; Female; Fiber Optic Technology; Humans; Lidocaine; Lung Diseases, Obstruc

1974
Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis.
    The American review of respiratory disease, 1971, Volume: 104, Issue:3

    Topics: Adult; Asthma; Autopsy; Bronchi; Bronchitis; Cartilage; Chronic Disease; Connective Tissue; Exocrine

1971
[Biochemical analysis of bronchial secretions in chronic obstructive lung disease (chronic bronchitis, asthma). I. Homogenizing of bronchial secretions with ultrasound and its importance for biochemical analysis].
    Pneumonologie. Pneumonology, 1971, Volume: 144, Issue:2

    Topics: Asthma; Bronchitis; Electrophoresis; Humans; Immunoelectrophoresis; Lung Diseases, Obstructive; Mucu

1971
[Biochemical analysis of bronchial secretions in chronic obstructive lung disease (chronic bronchitis and asthma). II. Classification of bronchial secretions on the basis of biochemical analyses].
    Pneumonologie. Pneumonology, 1971, Volume: 144, Issue:2

    Topics: Asthma; Bronchitis; Electrophoresis; Humans; Immunoelectrophoresis; Lung Diseases, Obstructive; Mucu

1971
[Composition of bronchial mucus in chronic obstructive bronchitis].
    Pneumonologie. Pneumonology, 1971, Volume: 144, Issue:1

    Topics: Adult; Aged; Bronchitis; Chronic Disease; Humans; Lung Diseases, Obstructive; Middle Aged; Mucus

1971
Humidification and mist therapy in chronic obstructive lung disease.
    International anesthesiology clinics, 1970,Fall, Volume: 8, Issue:3

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchodilator Agents; Chronic Disease; Deoxyribonuc

1970