guaifenesin has been researched along with Hypertrophy in 24 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have reported that triptolide inhibited pulmonary inflammation in patients with steroid-resistant asthma." | 7.81 | Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma. ( Chen, M; Huang, L; Jiang, S; Liang, R; Lin, X; Lv, Z; Shi, J; Zhang, W, 2015) |
| "We have reported that triptolide inhibited pulmonary inflammation in patients with steroid-resistant asthma." | 3.81 | Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma. ( Chen, M; Huang, L; Jiang, S; Liang, R; Lin, X; Lv, Z; Shi, J; Zhang, W, 2015) |
| "The most striking difference in the pulmonary inflammation induced in A(2B) receptor knockout (A(2B)KO) and wild-type mice was the lack of allergen-induced IL-4 release in the airways of A(2B)KO animals, in line with a significant reduction in IL-4 protein and mRNA levels in lung tissue." | 1.36 | Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice. ( Biaggioni, I; Blackburn, MR; Feoktistov, I; Goldstein, AE; Goleniewska, K; Mitchell, D; Morschl, E; Newcomb, DC; Novitskiy, SV; Peebles, RS; Polosukhin, VV; Ryzhov, S; Yin, H; Zaynagetdinov, R; Zhou, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (41.67) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Lv, Z | 1 |
| Zhang, W | 2 |
| Huang, L | 1 |
| Lin, X | 1 |
| Shi, J | 1 |
| Liang, R | 1 |
| Jiang, S | 1 |
| Siddiqui, S | 1 |
| Martin, JG | 1 |
| Oh, SY | 1 |
| Zheng, T | 1 |
| Kim, YK | 1 |
| Cohn, L | 1 |
| Homer, RJ | 1 |
| McKenzie, AN | 1 |
| Zhu, Z | 1 |
| Zaynagetdinov, R | 1 |
| Ryzhov, S | 1 |
| Goldstein, AE | 1 |
| Yin, H | 1 |
| Novitskiy, SV | 1 |
| Goleniewska, K | 1 |
| Polosukhin, VV | 1 |
| Newcomb, DC | 1 |
| Mitchell, D | 1 |
| Morschl, E | 1 |
| Zhou, Y | 1 |
| Blackburn, MR | 1 |
| Peebles, RS | 1 |
| Biaggioni, I | 1 |
| Feoktistov, I | 1 |
| Hattori, R | 1 |
| Shimizu, S | 1 |
| Majima, Y | 2 |
| Shimizu, T | 3 |
| Jeffery, P | 1 |
| Zhu, J | 1 |
| Melloni, P | 1 |
| Valls, R | 1 |
| Yuguero, M | 1 |
| Sáez, A | 1 |
| Muz, MH | 1 |
| Deveci, F | 1 |
| Bulut, Y | 1 |
| Ilhan, N | 1 |
| Yekeler, H | 1 |
| Turgut, T | 1 |
| Edwards, CW | 1 |
| Carlile, A | 1 |
| Pon, DJ | 1 |
| van Staden, CJ | 1 |
| Boulet, L | 1 |
| Rodger, IW | 1 |
| Takahashi, Y | 2 |
| Kawaguchi, S | 1 |
| Sakakura, Y | 2 |
| Fredriksen, F | 1 |
| Räisänen, S | 1 |
| Myklebust, R | 1 |
| Stenfors, LE | 1 |
| Takeuchi, K | 1 |
| Shimoyama, T | 1 |
| Wakabayashi, M | 1 |
| Kato, T | 1 |
| Kaneko, T | 1 |
| Horie, N | 1 |
| Ide, F | 1 |
| Jones, R | 1 |
| Shigemoto, H | 1 |
| Endo, S | 1 |
| Isomoto, T | 1 |
| Sano, K | 1 |
| Taguchi, K | 1 |
| Woodson, BT | 1 |
| Garancis, JC | 1 |
| Toohill, RJ | 1 |
| Hahn, HL | 1 |
| Mawdesley-Thomas, LE | 1 |
| Healey, P | 1 |
| Paisner, HM | 1 |
| Dunnill, MS | 1 |
| Weir, TW | 1 |
| Johnson, WC | 1 |
| Takizawa, T | 1 |
| Thurlbeck, WM | 1 |
| Anderson, AE | 1 |
| Foraker, AG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Measurement of Pharyngeal Sensitivity With the SENSITEST Device: Validation of the Diagnosis Algorithm for Sleep Disordered Breathing[NCT00885573] | 52 participants (Actual) | Interventional | 2008-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for guaifenesin and Hypertrophy
| Article | Year |
|---|---|
Structural aspects of airway remodeling in asthma.
Topics: Animals; Asthma; Cell Proliferation; Cytokines; Epithelial Cells; Extracellular Matrix Proteins; Fib | 2008 |
Mucin-producing elements and inflammatory cells.
Topics: Animals; Arachidonic Acids; Bronchitis; Cytokines; Eosinophilia; Exocrine Glands; Exocytosis; Goblet | 2002 |
22 other studies available for guaifenesin and Hypertrophy
| Article | Year |
|---|---|
Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Diseas | 2015 |
A critical role of SHP-1 in regulation of type 2 inflammation in the lung.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Epithelium; Hypertrophy | 2009 |
Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice.
Topics: Adenosine; Allergens; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chronic Disease; Disease Model | 2010 |
Prostaglandin E2 receptor EP2, EP3, and EP4 agonists inhibit antigen-induced mucus hypersecretion in the nasal epithelium of sensitized rats.
Topics: Alprostadil; Animals; Dinoprostone; Disease Models, Animal; Hypertrophy; Male; Metaplasia; Methyl Et | 2009 |
Mucoid degeneration of the anterior cruciate ligament with erosion of the lateral femoral condyle.
Topics: Adult; Anterior Cruciate Ligament; Bone Diseases; Femur; Humans; Hypertrophy; Male; Mucus | 2004 |
The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model.
Topics: Acetates; Airway Obstruction; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Cyclopropanes; Cyste | 2006 |
The larger bronchi in cryptogenic fibrosing alveolitis: a morphometric study.
Topics: Adult; Aged; Bronchi; Bronchitis; Exocrine Glands; Female; Humans; Hypertrophy; Male; Middle Aged; M | 1982 |
Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells.
Topics: Aerosols; Animals; Disease Models, Animal; Epithelium; Glycoproteins; Hyperplasia; Hypertrophy; Lung | 1994 |
Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin.
Topics: Animals; Endotoxins; Epithelium; Hyperplasia; Hypertrophy; Metaplasia; Mucus; Nasal Mucosa; Pancreat | 1996 |
Bacterial adherence to the surface and isolated cell epithelium of the palatine tonsils.
Topics: Adolescent; Adult; Bacterial Adhesion; Basement Membrane; Cell Membrane; Cell Separation; Child; Chi | 1996 |
Role of neutrophil elastase in endotoxin-induced mucus hypersecretion in rat nasal epithelium.
Topics: Animals; Endotoxins; Escherichia coli; Goblet Cells; Hypertrophy; Leukocyte Elastase; Male; Mucus; N | 2000 |
Adenomatoid hyperplasia of the palate mimicking clinically as a salivary gland tumor.
Topics: Adenoma, Pleomorphic; Adult; Case-Control Studies; Cell Division; Diagnosis, Differential; Follow-Up | 2001 |
Modification of mucus in animal models of disease.
Topics: Animals; Bronchi; Disease Models, Animal; Epithelium; Glycoproteins; Hydrogen-Ion Concentration; Hyp | 1977 |
Neonatal meconium obstruction in the ileum without mucoviscidosis.
Topics: Contrast Media; Cystic Fibrosis; Enema; Female; Humans; Hypertonic Solutions; Hypertrophy; Ileum; In | 1978 |
Histopathologic changes in snoring and obstructive sleep apnea syndrome.
Topics: Atrophy; Dilatation, Pathologic; Edema; Exocrine Glands; Fibrosis; Humans; Hypertrophy; Male; Metapl | 1991 |
[Clinically relevant mechanisms of mucus gland hypertrophy].
Topics: Animals; Autoradiography; Ferrets; Humans; Hypertrophy; Lung Diseases, Obstructive; Mucous Membrane; | 1988 |
Experimental bronchitis in lambs exposed to cigarette smoke.
Topics: Animals; Body Weight; Bronchi; Bronchitis; Cell Count; Environmental Exposure; Female; Hyperplasia; | 1973 |
Nasal obstruction.
Topics: Adenoids; Airway Obstruction; Ephedrine; Foreign Bodies; Hematoma; Histamine H1 Antagonists; Humans; | 1972 |
The contribution of morphology to the study of chronic obstructive lung disease.
Topics: Adult; Age Factors; Aged; Airway Obstruction; Biopsy; Bronchi; Bronchitis; Cilia; Exudates and Trans | 1974 |
Cheilitis glandularis.
Topics: Adult; Carcinoma, Squamous Cell; Cheilitis; Child; Child, Preschool; Dilatation; Exocrine Glands; Fe | 1971 |
Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis.
Topics: Adult; Asthma; Autopsy; Bronchi; Bronchitis; Cartilage; Chronic Disease; Connective Tissue; Exocrine | 1971 |
Bronchorrhea or bronchitis?
Topics: Bronchi; Bronchial Diseases; Bronchitis; Cilia; Diagnosis, Differential; Edema; Epithelium; Exocrine | 1971 |