Page last updated: 2024-10-28

guaifenesin and Hay Fever

guaifenesin has been researched along with Hay Fever in 50 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

ExcerptRelevanceReference
" Itching and the number of sneezes were noted, and the amount of secretion was measured and assayed for substance P."3.67Nasal challenge with serotonin in asymptomatic hay fever patients. ( Mygind, N; Schaffalitzky de Muckadell, OB; Tønnesen, P, 1987)
"Nasal mucociliary clearance was measured using a saccharin technique in 172 patients with perennial rhinitis (76 also had asthma) and in 121 patients with chronic infected rhinosinusitis (40 had asthma, 35 had bronchiectasis)."3.67Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease. ( Cole, PJ; Greenstone, MA; Mackay, IS; Stanley, PJ; Wilson, R, 1985)
" Results showed that both antihistamines, applied topically of dosed orally, reduced sneezing even when significant increases of histamine concentration in nasal secretions were evidenced immediately after NAC."2.68The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis. ( Clement, P; De Waele, M; Smitz, J; Wang, D, 1996)
"A total of 38 hayfever subjects were studied."2.67Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data. ( Cipolla, C; D'Antuono, G; Lugo, G; Occhionero, T; Orciari, P, 1990)
"The efficacy of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarine++ + dihydrochloride) in a dosage of 2 mg o."2.66Double-blind controlled crossover study comparing the protective effect of picumast dihydrochloride versus placebo following nasal allergen challenge. ( Bachert, C; Franke, W; Messinger, D, 1989)
"Eosinophilia was associated with asthma and with phlegm production."1.28Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study. ( O'Connor, GT; Sparrow, D; Tollerud, DJ; Weiss, ST, 1991)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199041 (82.00)18.7374
1990's6 (12.00)18.2507
2000's2 (4.00)29.6817
2010's1 (2.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mimura, T1
Usui, T1
Mori, M1
Aixinjueluo, W1
Funatsu, H1
Noma, H1
Amano, S1
Rogers, DF1
Brooks, CD1
Nelson, AL1
Metzler, C1
Asakura, K1
Enomoto, K1
Ara, H1
Azuma, E1
Kataura, A1
Wanner, A1
Ohtsuka, H1
Okuda, M3
Borum, P1
Mygind, N2
Guercio, JP1
Birch, S1
Fernandez, RJ1
Sackner, MA1
Wang, D1
Clement, P1
Smitz, J1
De Waele, M1
Iguchi, Y1
Yao, K1
Okamoto, M1
Majima, M1
Kramer, MF1
Ostertag, P1
Pfrogner, E1
Rasp, G1
Schorn, K1
Hochstrasser, K1
Wittmann, J1
Lin, MT1
Collins-Williams, C1
Otsuka, H1
Liu, HY1
Giday, Z1
Moore, BF1
Kim, GR1
Chung, TI1
Choi, SE1
Eggleston, PA1
Hendley, JO1
Gwaltney, JM2
Eggleston, AW1
Leavell, BS1
Pelikan, Z1
Blair, H1
Viner, AS1
Hisamatsu, K1
Kaulbach, HC1
Igarashi, Y1
Mullol, J1
White, MV1
Kaliner, MA1
Tollerud, DJ1
O'Connor, GT1
Sparrow, D1
Weiss, ST1
Cipolla, C1
Occhionero, T1
Orciari, P1
Lugo, G1
D'Antuono, G1
Makowska, W1
Zawisza, E1
Tønnesen, P1
Schaffalitzky de Muckadell, OB1
Franke, W1
Bachert, C1
Messinger, D1
Karlsson, G1
Pipkorn, U2
Passali, D1
Basterra, J1
Matoses, F1
Latorre, E1
Ferrando, C1
Granerus, G1
Proud, D1
Kagey-Sobotka, A1
Norman, PS1
Lichtenstein, LM1
Naclerio, RM1
Ado, AD1
Shustova, VI1
Pol'ner, SA1
Gurgenidze, GV1
Gamkrelidze, AG1
Baraban, EI1
Stanley, PJ1
Wilson, R1
Greenstone, MA1
Mackay, IS1
Cole, PJ1
Bennich, H1
Johansson, SG1
Tse, KS2
Wicher, K2
Arbesman, CE3
Williams, RB1
Lamerz, R1
Fateh-Moghadam, A1
Gastpar, H1
Benda, J1
Vacková, L1
Spicák, V1
Kosoy, J1
Trieff, NM1
Winkelmann, P1
Bailey, BJ1
Crifò, S1
Antonelli, M1
Solomon, WR1
Kellner, G1
Majer, EH1
Dolovich, J1
Back, N1
Smith, RE1
Casanova-Roig, R1
Wells, DE1
Melon, J1
Millman, M1
Grundon, W1
Steffl, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005284]0 participants Observational1985-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for guaifenesin and Hay Fever

ArticleYear
Airway hypersecretion in allergic rhinitis and asthma: new pharmacotherapy.
    Current allergy and asthma reports, 2003, Volume: 3, Issue:3

    Topics: Asthma; Capillary Permeability; Chloride Channels; Glucocorticoids; Histamine Antagonists; Humans; M

2003
[Role of basophilic granular cells in nasal allergy (author's transl)].
    Rinsho byori. The Japanese journal of clinical pathology, 1981, Volume: 29, Issue:12

    Topics: Animals; Basophils; Chemotactic Factors; Humans; Leukocyte Count; Mast Cells; Mice; Mucus; Nasal Muc

1981
Immunoglobulin E and immediate hypersensitivity.
    Vox sanguinis, 1970, Volume: 19, Issue:1

    Topics: Adolescent; Antibodies; Antibodies, Anti-Idiotypic; Antibody Formation; Ascariasis; Asthma; Binding

1970

Trials

11 trials available for guaifenesin and Hay Fever

ArticleYear
Effect of flurbiprofen, a cyclooxygenase inhibiting drug, on induced allergic rhinitis.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 1

    Topics: Adult; Analysis of Variance; Female; Flurbiprofen; Humans; Middle Aged; Mucus; Nasal Provocation Tes

1984
Inhibition of the immediate allergic reaction in the nose by the beta-2 adrenostimulant fenoterol.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:1

    Topics: Adult; Aerosols; Allergens; Dose-Response Relationship, Drug; Double-Blind Method; Ethanolamines; Fe

1980
The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis.
    Acta oto-rhino-laryngologica Belgica, 1996, Volume: 50, Issue:1

    Topics: Adult; Airway Resistance; Anti-Allergic Agents; Bronchodilator Agents; Budesonide; Cimetidine; Femal

1996
Intranasal beclomethasone dipropionate for perennial allergic rhinitis.
    Canadian Medical Association journal, 1977, Apr-23, Volume: 116, Issue:8

    Topics: Administration, Intranasal; Adolescent; Adult; Beclomethasone; Child; Clinical Trials as Topic; Eosi

1977
A double blind trial of a 2% solution of sodium cromoglycate in perennial rhinitis.
    Clinical allergy, 1975, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Allergens; Asthma; Child; Clinical Trials as Topic; Cromolyn Sodium; Desensitizat

1975
Effects of nedocromil sodium on allergen-induced rhinitis in humans.
    The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:2

    Topics: Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Male; Mucus;

1992
Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data.
    Magnesium research, 1990, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Calcium; Evaluation Studies as Topic; Female; Humans; Lacrimal Apparatus; Magnesi

1990
Double-blind controlled crossover study comparing the protective effect of picumast dihydrochloride versus placebo following nasal allergen challenge.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:10A

    Topics: Adult; Coumarins; Double-Blind Method; Histamine H1 Antagonists; Humans; Manometry; Middle Aged; Muc

1989
Natural allergen exposure does not influence the density of goblet cells in the nasal mucosa of patients with seasonal allergic rhinitis.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1989, Volume: 51, Issue:3

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Budesonide; Clinical Trials as Topic; Doub

1989
The effect of a histamine synthesis inhibitor on the immediate nasal allergic reaction.
    Allergy, 1987, Volume: 42, Issue:7

    Topics: Adult; Carboxy-Lyases; Female; Histamine; Histamine Antagonists; Histidine; Histidine Decarboxylase;

1987
[The physiopathology of inflammatory nasal mucosa lesions. The significance of the galenic type of local therapeutic agents].
    Medizinische Klinik, 1970, Feb-20, Volume: 65, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cilia; Evaluation Studies as Topic;

1970

Other Studies

36 other studies available for guaifenesin and Hay Fever

ArticleYear
Immunochromatographic assay for measurement of total IgE in tears, nasal mucus, and saliva of patients with allergic rhinoconjunctivitis.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2010, Volume: 47, Issue:10

    Topics: Adolescent; Adult; Conjunctivitis, Allergic; Cross-Sectional Studies; Female; Humans; Immunoassay; I

2010
Nasal responsiveness to methacholine stimulation in allergic rhinitis patients.
    Archives of oto-rhino-laryngology, 1984, Volume: 239, Issue:3

    Topics: Administration, Topical; Humans; Methacholine Compounds; Mucus; Nasal Provocation Tests; Rhinitis, A

1984
Allergic mucociliary dysfunction.
    The Laryngoscope, 1983, Volume: 93, Issue:1

    Topics: Antigens; Asthma; Cilia; Humans; Mucous Membrane; Mucus; Rhinitis, Allergic, Seasonal; SRS-A; Trache

1983
Deposition of ragweed pollen and extract on nasal mucosa of patients with allergic rhinitis: effect on nasal airflow resistance and nasal mucus velocity.
    The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:1

    Topics: Adult; Biological Transport; Female; Humans; Male; Middle Aged; Mucus; Nasal Mucosa; Nasal Provocati

1980
[The reaction of the nasal mucosa in allergic rhinitis to cold saline stimulus].
    Nihon Jibiinkoka Gakkai kaiho, 1998, Volume: 101, Issue:6

    Topics: Adult; Albumins; Cold Temperature; Female; Humans; Male; Molecular Weight; Mucus; Nasal Mucosa; Prot

1998
Nasal interleukin-5, immunoglobulin E, eosinophilic cationic protein, and soluble intercellular adhesion molecule-1 in chronic sinusitis, allergic rhinitis, and nasal polyposis.
    The Laryngoscope, 2000, Volume: 110, Issue:6

    Topics: Adult; Aged; Blood Proteins; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Eosinophil Granule

2000
[Metabolic enzymes in human nasal mucus under physiological and pathophysiological conditions of the mucous membrane (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1975, Volume: 54, Issue:7

    Topics: Acid Phosphatase; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bacterial

1975
Basophilic cells in allergic nasal secretions.
    Archives of oto-rhino-laryngology, 1977, Feb-15, Volume: 214, Issue:4

    Topics: Adolescent; Adult; Basophils; Cell Count; Humans; Immunotherapy; Mast Cells; Middle Aged; Mucus; Nas

1977
Possible pathogenetic mechanisms producing bovine milk protein inducible malabsorption: a hypothesis.
    Annals of allergy, 1977, Volume: 39, Issue:1

    Topics: Adolescent; Animals; Capillary Permeability; Exocrine Glands; Feces; Female; Food Hypersensitivity;

1977
The eosinophilic changes in rhinorrhea due to nasal allergy.
    Yonsei medical journal, 1977, Volume: 18, Issue:2

    Topics: Eosinophils; Humans; Leukocyte Count; Mucus; Nasal Mucosa; Rhinitis, Allergic, Seasonal

1977
Histamine in nasal secretions.
    International archives of allergy and applied immunology, 1978, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Male; Mucus; Nasal Mucosa; Rhinitis, Allergic,

1978
Late and delayed responses of the nasal mucosa to allergen challenge.
    Annals of allergy, 1978, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Allergens; Child; Female; Humans; Hypersensitivity, Delayed; Male; Middle Aged; M

1978
[A study on histamine and histaminase activity in nasal allergy (author's transl)].
    Nihon Jibiinkoka Gakkai kaiho, 1975, Feb-20, Volume: 78, Issue:2

    Topics: Adult; Amine Oxidase (Copper-Containing); Female; Histamine; Humans; Male; Mucus; Nasal Mucosa; Rhin

1975
Response of the human nasal mucous membrane to anti-human IgE serum.
    Archives of oto-rhino-laryngology, 1975, Oct-30, Volume: 211, Issue:1

    Topics: Administration, Intranasal; Adolescent; Adult; Bradykinin; Child; Desensitization, Immunologic; Dust

1975
Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study.
    The American review of respiratory disease, 1991, Volume: 144, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Asthma; Eosinophilia; Humans; Hypersensitivity; Immunoglobuli

1991
[Cytological examination of nasal discharge before and after local administration of flunisolide (syntaris)].
    Otolaryngologia polska = The Polish otolaryngology, 1990, Volume: 44, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Anti-Inflammatory Agents; Female; Fluocinolone Aceton

1990
Nasal challenge with serotonin in asymptomatic hay fever patients.
    Allergy, 1987, Volume: 42, Issue:6

    Topics: Adult; Airway Resistance; Female; Humans; Male; Mucus; Nasal Mucosa; Nasal Provocation Tests; Prurit

1987
Allergy in childhood.
    Rhinology, 1986, Volume: 24, Issue:1

    Topics: Beclomethasone; Child; Cromolyn Sodium; Desensitization, Immunologic; Humans; Manometry; Mucus; Nasa

1986
[Immunologic study of mucus in patients with allergic rhinopathy and bronchial asthma].
    Anales otorrinolaringologicos ibero-americanos, 1988, Volume: 15, Issue:5

    Topics: Asthma; Humans; Immunoglobulins; Mucus; Nasal Mucosa; Rhinitis, Allergic, Seasonal

1988
[Clinico-functional and allergological characteristics of seasonal allergic rhinitis].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:2

    Topics: Allergens; Female; Humans; Immunoglobulin E; Male; Mucus; Nasal Mucosa; Nasal Provocation Tests; Rhi

1988
[Determining allergen-specific IgE in nasal secretion in the diagnosis of pollinosis].
    Klinicheskaia meditsina, 1987, Volume: 65, Issue:7

    Topics: Conjunctivitis, Allergic; Humans; Immunoglobulin E; Mucus; Nasal Mucosa; Pollen; Rhinitis, Allergic,

1987
Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease.
    British journal of diseases of the chest, 1985, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Asthma; Bronchiectasis; Cilia; Female; Humans; Male; Middle Aged; Mucus; Nose; Rh

1985
IgE antibodies in nasal secretions of ragweed-allergic subjects.
    The Journal of allergy, 1970, Volume: 46, Issue:6

    Topics: Antibodies; Antigen-Antibody Reactions; gamma-Globulins; Humans; Immunodiffusion; Immunoglobulins; M

1970
Allergic rhinitis or virus cold? Nasal smear eosinophilia in differential diagnosis.
    Annals of allergy, 1972, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Common Cold; Diagnosis, Differential; Eosinophilia; Female; Humans; Male; Mucus;

1972
[Immunoglobulin E. Biochemical, immunological properties and clinical significance (author's transl)].
    Klinische Wochenschrift, 1974, Jan-01, Volume: 52, Issue:1

    Topics: Antibodies; Antibodies, Anti-Idiotypic; Asthma; Basophils; Binding Sites, Antibody; Chemical Phenome

1974
[Levels of immunoglobulins in the blood serum and nasal secretions in allergic and nonallergic inflammations of the upper respiratory pathways in childhood].
    Ceskoslovenska otolaryngologie, 1974, Volume: 23, Issue:6

    Topics: Adolescent; Age Factors; Child; Humans; Immunoglobulins; Mucus; Nasal Mucosa; Nose; Rhinitis, Allerg

1974
Effect of immunotherapy on appearance of antibodies to ragweed in external secretions.
    The Journal of allergy and clinical immunology, 1973, Volume: 51, Issue:4

    Topics: Adsorption; Animals; Antibodies; Goats; Hemagglutination Inhibition Tests; Hemagglutination Tests; H

1973
Glucose in nasal secretions. Diagnostic significance.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Aged; Cerebrospinal Fluid Rhinorrhea; Child; Child, Preschool; Diagnosis, Differe

1972
[Electrolytes and proteins of nasal secretion in mucoviscidosis].
    Bollettino della Societa italiana di biologia sperimentale, 1971, Jun-15, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Body Fluids; Child; Child, Preschool; Cystic Fibrosis; Electrolytes; Humans; Mucu

1971
Comparative effects of transient body surface cooling, recumbency, and induced obstruction in allergic rhinitis and control subjects.
    The Journal of allergy, 1966, Volume: 37, Issue:4

    Topics: Adult; Body Temperature; Female; Humans; Humidity; Hypersensitivity; Male; Mucus; Nose; Posture; Res

1966
[Nasal secretion as an indicator of the functional state of the mucosa].
    Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1969, Volume: 103, Issue:10

    Topics: Diagnosis, Differential; Humans; Mucus; Nasal Mucosa; Rhinitis; Rhinitis, Allergic, Seasonal

1969
Kinin-like activity in nasal secretions of allergic patients.
    International archives of allergy and applied immunology, 1970, Volume: 38, Issue:4

    Topics: Aerosols; Carboxypeptidases; Chymotrypsin; Dimercaprol; Endopeptidases; Humans; Kinins; Mucus; Muscl

1970
The effect of antihistamines on nasal smear eosinophiles in patients with allergic rhinitis.
    Annals of allergy, 1968, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Diphenhydramine; Eosinophils; Female; Humans; Male; Midd

1968
[Contribution to the study of the secretory activity of the nasal mucosa. Characteristics of the permeability of the nasal epithelium. Chemical composition of the nucus. The mechanism of its formation under normal conditions and during paroxystic hypersec
    Acta oto-rhino-laryngologica Belgica, 1968, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Animals; Autonomic Agents; Chlorides; Common Cold; Female; Guinea Pigs; Humans; M

1968
Use of acetylcysteine in bronchial asthma and emphysema.
    The Journal of asthma research, 1969, Volume: 6, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aerosols; Aged; Asthma; Bronchitis; Child; Chronic Disease; Ethan

1969
[On the problem of acidity and alkalinity of secretions in allergic diseases of the nasal mucosa].
    Ceskoslovenska otolaryngologie, 1966, Volume: 15, Issue:4

    Topics: Humans; Hydrogen-Ion Concentration; Mucus; Rhinitis, Allergic, Seasonal

1966