Page last updated: 2024-10-28

guaifenesin and HIV Coinfection

guaifenesin has been researched along with HIV Coinfection in 17 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

ExcerptRelevanceReference
"PHI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea) is a rationally designed novel thiophene thiourea nonnucleoside reverse transcriptase inhibitor (NNRTI) with potent anti-HIV activity against the wild-type and drug-resistant primary clinical human immunodeficiency virus (HIV-1) isolates."3.72PHI-443: a novel noncontraceptive broad-spectrum anti-human immunodeficiency virus microbicide. ( D'Cruz, OJ; Samuel, P; Uckun, FM, 2004)
"Guaifenesin therapy was associated with improved SNOT-16 scores, although there was not a detectable improvement in MCT."2.71Alterations of nasal mucociliary clearance in association with HIV infection and the effect of guaifenesin therapy. ( Calhoun, KH; Rosen, EJ, 2005)
"Women with bacterial vaginosis (BV) have a higher risk of HIV transmission but the cause of risk is unknown."1.35Effect of mucosal fluid from women with bacterial vaginosis on HIV trans-infection mediated by dendritic cells. ( Landay, AL; Martinson, JA; Simoes, JA; Spear, GT; St John, EP; Zariffard, MR, 2009)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (23.53)18.2507
2000's5 (29.41)29.6817
2010's5 (29.41)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Rosen, EJ1
Calhoun, KH1
Wawrose, SF1
Tami, TA1
Amoils, CP1
Schaefer, A1
Yang, B1
Schroeder, HA1
Harit, D2
Humphry, MS1
Ravel, J1
Lai, SK4
Hoang, T1
Toler, E1
DeLong, K1
Mafunda, NA1
Bloom, SM1
Zierden, HC1
Moench, TR1
Coleman, JS1
Hanes, J2
Kwon, DS1
Cone, RA1
Ensign, LM1
Gundavarapu, S1
Mishra, NC1
Singh, SP1
Langley, RJ1
Saeed, AI1
Feghali-Bostwick, CA1
McIntosh, JM1
Hutt, J1
Hegde, R1
Buch, S1
Sopori, ML1
Stax, MJ1
Mouser, EE1
van Montfort, T1
Sanders, RW1
de Vries, HJ1
Dekker, HL1
Herrera, C1
Speijer, D1
Pollakis, G1
Paxton, WA1
Chen, A1
McKinley, SA1
Shi, F1
Wang, S1
Mucha, PJ1
Forest, MG1
Gunn, B1
Schneider, J1
Shansab, M1
Bastian, AR1
Fahrbach, K1
Smith, A1
Mahan, A1
Karim, M1
Licht, A1
Zvonar, I1
Tedesco, J1
Anderson, M1
Chapel, A1
Suscovich, T1
Malaspina, D1
Streeck, H1
Walker, BD1
Kim, A1
Lauer, G1
Altfeld, M1
Pillai, S1
Szleifer, I1
Kelleher, NL1
Kiser, PF1
Hope, TJ2
Alter, G1
St John, EP1
Zariffard, MR1
Martinson, JA1
Simoes, JA1
Landay, AL1
Spear, GT1
Hida, K1
Shukair, S1
Wang, YY1
Figueiredo, A1
Cone, R1
Graham, SM1
Masese, L1
Gitau, R1
Richardson, BA1
Mandaliya, K1
Peshu, N1
Jaoko, W1
Ndinya-Achola, J1
Overbaugh, J1
McClelland, RS1
D'Cruz, OJ1
Samuel, P1
Uckun, FM1
Verkuyl, DA1
Mascolini, M1
Ellerbrock, TV1
Lennox, JL1
Clancy, KA1
Schinazi, RF1
Wright, TC1
Pratt-Palmore, M1
Evans-Strickfaden, T1
Schnell, C1
Pai, R1
Conley, LJ1
Parrish-Kohler, EE1
Bush, TJ1
Tatti, K1
Hart, CE1

Trials

2 trials available for guaifenesin and HIV Coinfection

ArticleYear
Alterations of nasal mucociliary clearance in association with HIV infection and the effect of guaifenesin therapy.
    The Laryngoscope, 2005, Volume: 115, Issue:1

    Topics: Adult; Double-Blind Method; Expectorants; Female; Guaifenesin; HIV Infections; Humans; Male; Middle

2005
The role of guaifenesin in the treatment of sinonasal disease in patients infected with the human immunodeficiency virus (HIV).
    The Laryngoscope, 1992, Volume: 102, Issue:11

    Topics: Adult; CD4-Positive T-Lymphocytes; Chronic Disease; Double-Blind Method; Guaifenesin; HIV Infections

1992

Other Studies

15 other studies available for guaifenesin and HIV Coinfection

ArticleYear
Broadly neutralizing antibodies consistently trap HIV-1 in fresh cervicovaginal mucus from select individuals.
    Acta biomaterialia, 2023, 10-01, Volume: 169

    Topics: Broadly Neutralizing Antibodies; Cervix Uteri; Female; HIV Infections; HIV-1; Humans; Immunoglobulin

2023
Editorial Note: HIV gp120 Induces Mucus Formation in Human Bronchial Epithelial Cells through CXCR4/α7-Nicotinic Acetylcholine Receptors.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Epithelial Cells; HIV Infections; Humans; Mucus; Receptors,

2023
The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis.
    PLoS pathogens, 2020, Volume: 16, Issue:1

    Topics: Adult; Bacteria; Cervix Uteri; Coinfection; Female; HIV Infections; HIV-1; Humans; Microbiota; Middl

2020
HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antiretroviral Therapy, Highly Active; Bronchi; Ep

2013
Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: CD4-Positive T-Lymphocytes; Cell Adhesion Molecules; Cell Line, Tumor; Colon; Dendritic Cells; env G

2015
Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Agglutination; Cervix Uteri; Female; HIV; HIV Infections; Humans; Immunoglobulin A, Secretory; Model

2015
Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.
    Mucosal immunology, 2016, Volume: 9, Issue:6

    Topics: Antibody Affinity; CA-125 Antigen; Female; Glycosylation; HIV Antibodies; HIV Infections; HIV-1; Hum

2016
Effect of mucosal fluid from women with bacterial vaginosis on HIV trans-infection mediated by dendritic cells.
    Virology, 2009, Mar-01, Volume: 385, Issue:1

    Topics: Adjuvants, Immunologic; Cell Adhesion Molecules; Dendritic Cells; Female; HIV Infections; HIV-1; Hum

2009
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus.
    Journal of virology, 2009, Volume: 83, Issue:21

    Topics: Animals; Cell Line; Cervix Uteri; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Hyd

2009
Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.
    Sexually transmitted infections, 2011, Volume: 87, Issue:2

    Topics: Adult; Anti-HIV Agents; Cervix Uteri; Female; HIV Infections; HIV-1; Humans; Mucus; Prospective Stud

2011
PHI-443: a novel noncontraceptive broad-spectrum anti-human immunodeficiency virus microbicide.
    Biology of reproduction, 2004, Volume: 71, Issue:6

    Topics: Absorption; Animals; Anti-Infective Agents; Biomechanical Phenomena; Cervix Uteri; Drug Stability; E

2004
Mouth operated mucus extractors: safe to use?
    British journal of obstetrics and gynaecology, 1995, Volume: 102, Issue:10

    Topics: HIV Infections; Humans; Infant; Infant Care; Infant, Newborn; Infectious Disease Transmission, Patie

1995
The drugs we've got...the drugs we're getting...beyond blood. A three-part look at the Fourth Conference on Retroviruses and Opportunistic Infections.
    Journal of the International Association of Physicians in AIDS Care, 1997, Volume: 3, Issue:4

    Topics: Anti-HIV Agents; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infe

1997
Viral load and progression.
    PI perspective, 1997, Issue:No 21

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV

1997
Cellular replication of human immunodeficiency virus type 1 occurs in vaginal secretions.
    The Journal of infectious diseases, 2001, Jul-01, Volume: 184, Issue:1

    Topics: Adolescent; Adult; Cohort Studies; Drug Resistance, Microbial; Female; HIV Infections; HIV-1; Humans

2001