Page last updated: 2024-10-28

guaifenesin and Gastrointestinal Hemorrhage

guaifenesin has been researched along with Gastrointestinal Hemorrhage in 32 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Aspirin-induced gastritis and gastrointestinal hemorrhage were reviewed and discussed on the basis of currently available literature."7.65Aspirin-induced gastritis and gastrointestinal bleeding. ( Gartner, AH, 1976)
" Our patient had arthritis of the hips and chronic atrial fibrillation and was on warfarin therapy for stroke prevention; less than a week after starting celecoxib therapy, gastrointestinal bleeding and hypoprothrombinemia occurred."3.70Cyclooxygenase-2 inhibitor celecoxib: a possible cause of gastropathy and hypoprothrombinemia. ( Davis, JV; Linder, JD; Mönkemüller, KE; Wilcox, CM, 2000)
"Aspirin-induced gastritis and gastrointestinal hemorrhage were reviewed and discussed on the basis of currently available literature."3.65Aspirin-induced gastritis and gastrointestinal bleeding. ( Gartner, AH, 1976)
"Patients with circular rectal tumors seldom had long-term palliative effects of cryosurgery."2.69Palliative cryosurgery for rectal carcinoma. ( Meijer, S; Rahusen, FD; van der Plas, LG, 1999)
", concurrent disease, physical or sociopsychologic stress, dietary and genetic status), the intrinsic pharmacokinetic and physicochemical differences in these drugs account for variations in their rate of absorption or uptake from the circulation into the GI mucosa."2.37Gastrointestinal damage from nonsteroidal anti-inflammatory drugs. ( Rainsford, KD, 1988)
"Chronic gastric ulcer is linked to aspirin intake in patients with rheumatic disease, and epidemiologically in all heavy aspirin users; paradoxically, in only one epidemiologic study was a significant association found between acetaminophen intake and chronic gastric ulcer."2.36Gastrointestinal effects of antipyretic analgesics. ( Ivey, KJ, 1983)
"Although rectal pain is often not commonly associated with prolapse, it bothers many women and motivates older women to undergo evaluation."1.62Rectal Prolapse: Age-Related Differences in Clinical Presentation and What Bothers Women Most. ( Arnow, KD; Gurland, BH; Lee, A; Neshatian, L; Trickey, AW, 2021)
"Few patients with anorectal foreign bodies will freely admit to transanal introduction."1.30Management of anorectal foreign bodies: a cause of obscure anal pain. ( Eu, KW; Ho, YH; Leong, A; Nyam, D; Ooi, BS; Seow-Choen, F, 1998)
" The reduction in gastric bleeding with the 50-microgram dosage of misoprostol was directly related to the reduction in acid secretion."1.27Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion. ( Hunt, JN; Jiang, CL; Kessler, L; Smith, JL, 1983)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199014 (43.75)18.7374
1990's7 (21.88)18.2507
2000's4 (12.50)29.6817
2010's6 (18.75)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Neshatian, L1
Lee, A1
Trickey, AW1
Arnow, KD1
Gurland, BH1
Rubin, JE1
Costa, MO1
Hill, JE1
Kittrell, HE1
Fernando, C1
Huang, Y1
O'Connor, B1
Harding, JC1
Amagase, K1
Yoshida, Y1
Hara, D1
Murakami, T1
Takeuchi, K1
Ford, AC1
Moayyedi, P1
Bercik, P1
Morgan, DG1
Bolino, C1
Pintos-Sanchez, MI1
Reinisch, W1
Baltar-Arias, R1
Ulla-Rocha, JL1
Moreno-López, E1
Fernández-Salgado, E1
Vázquez-Rodríguez, S1
Díaz-Saa, W1
Carrera-González, V1
Vázquez-Astray, E1
Adelstein, BA1
Irwig, L1
Macaskill, P1
Turner, RM1
Chan, SF1
Katelaris, PH1
Geinitz, H1
Thamm, R1
Keller, M1
Astner, ST1
Heinrich, C1
Scholz, C1
Pehl, C1
Kerndl, S1
Prause, N1
Busch, R1
Molls, M1
Zimmermann, FB1
Yeoh, EE1
Fraser, RJ1
McGowan, RE1
Botten, RJ1
Di Matteo, AC1
Roos, DE1
Penniment, MG1
Borg, MF1
Chiang, JM1
Changchien, CR1
Chen, JR1
Heemsbergen, WD1
Peeters, ST1
Koper, PC1
Hoogeman, MS1
Lebesque, JV1
Ivey, KJ1
Lamabadusuriya, SP1
Chandrasoma, PT1
de Silva, DD1
Hunt, JN1
Smith, JL1
Jiang, CL1
Kessler, L1
Fernández, AG1
Salcedo, C1
Palacios, JM1
Nosálová, V1
Juránek, I1
Babulová, A1
Ooi, BS1
Ho, YH1
Eu, KW1
Nyam, D1
Leong, A1
Seow-Choen, F1
Meijer, S1
Rahusen, FD1
van der Plas, LG1
Busca, M1
Linder, JD1
Mönkemüller, KE1
Davis, JV1
Wilcox, CM1
Gartner, AH1
Meshorer, A1
Tabata, M1
Tomomasa, T1
Itoh, K1
Miyashita, M1
Hyman, PE1
Tanaka, T1
Kuroume, T1
Durham, RM1
Shapiro, MJ1
Rainsford, KD1
Wallace, JL1
Lacy, ER2
Ojeda, VJ1
Levitt, S1
Ryan, G1
Laurence, BH1
Cathcart, RS1
Fitts, CT1
McAlhany, JC1
Spicer, SS1
Paradny, R1
Kark, AE1
Hirsch, A1
Hoon, JR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PROstate CAncer Radiotherapy: Its Real Impact on Bowel Symptoms & Quality of Life Today, Measured by the EORTC QLQ C30 & Specific PRT20 Module.[NCT05880446]30 participants (Anticipated)Interventional2023-09-30Not yet recruiting
Complications in the Management and Removal of Rectal and Vaginal Foreign Bodies[NCT05888363]78 participants (Actual)Observational2020-12-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for guaifenesin and Gastrointestinal Hemorrhage

ArticleYear
Solitary rectal ulcer syndrome: an endoscopic and histological presentation and literature review.
    International journal of colorectal disease, 2006, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Biopsy; Colonoscopy; Constipation; Diagnostic Errors; Diarrhea; Female; Gastroint

2006
Gastrointestinal effects of antipyretic analgesics.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonate

1983
Stress gastritis revisited.
    The Surgical clinics of North America, 1991, Volume: 71, Issue:4

    Topics: Antacids; Bicarbonates; Cimetidine; Epithelium; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrha

1991
Gastrointestinal damage from nonsteroidal anti-inflammatory drugs.
    Toxicologic pathology, 1988, Volume: 16, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Environment; Free Radicals; Gastric

1988
Gastric mucosal defense after superficial injury.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1987, Volume: 10, Issue:3

    Topics: Animals; Cell Movement; Dogs; Epithelial Cells; Epithelium; Ethanol; Gastric Mucosa; Gastrointestina

1987
Prostaglandins and histological changes in the gastric mucosa.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:11 Suppl

    Topics: Adaptation, Physiological; Animals; Ethanol; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Mi

1985

Trials

2 trials available for guaifenesin and Gastrointestinal Hemorrhage

ArticleYear
Evidence for efficacy without increased toxicity of hypofractionated radiotherapy for prostate carcinoma: early results of a Phase III randomized trial.
    International journal of radiation oncology, biology, physics, 2003, Mar-15, Volume: 55, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Defecation; Dose Fractionation, Radiation; Gastrointestin

2003
Palliative cryosurgery for rectal carcinoma.
    International journal of colorectal disease, 1999, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Cryosurgery; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged

1999

Other Studies

24 other studies available for guaifenesin and Gastrointestinal Hemorrhage

ArticleYear
Rectal Prolapse: Age-Related Differences in Clinical Presentation and What Bothers Women Most.
    Diseases of the colon and rectum, 2021, Volume: 64, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Fecal Incontinence; Female; Gastrointestinal Hemorrhage; Human

2021
Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with "Brachyspira hampsonii" strain 30446.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animal Husbandry; Animals; Brachyspira; Colitis; Colon; Diarrhea; Feces; Gastrointestinal Hemorrhage

2013
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:1

    Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage;

2013
Lack of utility of symptoms and signs at first presentation as predictors of inflammatory bowel disease in secondary care.
    The American journal of gastroenterology, 2015, Volume: 110, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Biopsy; Colitis, Ulcerative; Colon; Colonoscopy;

2015
Rectal polyp as presentation form of colitis cystica profunda.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:1

    Topics: Colitis; Colonoscopy; Cysts; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Polyps; Middle

2010
Who needs colonoscopy to identify colorectal cancer? Bowel symptoms do not add substantially to age and other medical history.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Colonoscopy; Colorectal Ne

2010
Longitudinal study of intestinal symptoms and fecal continence in patients with conformal radiotherapy for prostate cancer.
    International journal of radiation oncology, biology, physics, 2011, Apr-01, Volume: 79, Issue:5

    Topics: Aged; Aged, 80 and over; Defecation; Fecal Incontinence; Gastrointestinal Hemorrhage; Humans; Male;

2011
Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage.
    International journal of radiation oncology, biology, physics, 2006, Sep-01, Volume: 66, Issue:1

    Topics: Acute Disease; Aged; Clinical Trials, Phase III as Topic; Fecal Incontinence; Gastrointestinal Hemor

2006
An epidemic of blood and mucus diarrhoea complicated by disseminated intravascular coagulation.
    The Ceylon medical journal, 1984, Volume: 29, Issue:4

    Topics: Child; Child, Preschool; Diarrhea, Infantile; Disease Outbreaks; Disseminated Intravascular Coagulat

1984
Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion.
    Digestive diseases and sciences, 1983, Volume: 28, Issue:10

    Topics: Alprostadil; Aspirin; Calcium; Chlorides; DNA; Double-Blind Method; Drug Evaluation; Gastric Juice;

1983
Aspirin, salicylate and gastrointestinal injury.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Detergents; Gastric Mucosa; Gas

1995
Effect of trapencaine and some of its derivatives on gastric wall mucus in stressed rats.
    Die Pharmazie, 1995, Volume: 50, Issue:6

    Topics: Anesthetics, Local; Animals; Carbamates; Cold Temperature; Female; Gastric Mucosa; Gastrointestinal

1995
Management of anorectal foreign bodies: a cause of obscure anal pain.
    The Australian and New Zealand journal of surgery, 1998, Volume: 68, Issue:12

    Topics: Adolescent; Adult; Aged; Anal Canal; Anesthesia, General; Bronchopneumonia; Colon, Sigmoid; Consciou

1998
[A new system for noninvasive sampling of the upper gastrointestinal tract].
    Recenti progressi in medicina, 1999, Volume: 90, Issue:11

    Topics: Adult; Capsules; Child; Endoscopy; Evaluation Studies as Topic; Gastrointestinal Diseases; Gastroint

1999
Cyclooxygenase-2 inhibitor celecoxib: a possible cause of gastropathy and hypoprothrombinemia.
    Southern medical journal, 2000, Volume: 93, Issue:9

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthritis; Atrial Fibrillation; Bicar

2000
Aspirin-induced gastritis and gastrointestinal bleeding.
    Journal of the American Dental Association (1939), 1976, Volume: 93, Issue:1

    Topics: Administration, Oral; Aspirin; Blood Platelets; Delayed-Action Preparations; Dose-Response Relations

1976
Histological findings in rabbits which died with symptoms of mucoid enteritis.
    Laboratory animals, 1976, Volume: 10, Issue:3

    Topics: Animals; Cecal Diseases; Cecum; Colon; Enteritis; Gastrointestinal Hemorrhage; Mucus; Rabbits

1976
Developmental changes in gastric mucus gel thickness: responsiveness to 16,16-dimethyl prostaglandin E2 and mucosal protection in the rat.
    Pediatric research, 1992, Volume: 31, Issue:2

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Animals, Newborn; Ethanol; Gastric Mucosa; Gastrointestinal

1992
Increased resistance of the rat gastric mucosa to hemorrhagic damage after exposure to an irritant. Role of the "mucoid cap" and prostaglandin synthesis.
    Gastroenterology, 1988, Volume: 94, Issue:1

    Topics: Animals; Ethanol; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Mucus; Prostaglandins; Rats; Ra

1988
Cystic fibrosis, Crohn's colitis, and adult meconium ileus equivalent.
    Diseases of the colon and rectum, 1986, Volume: 29, Issue:9

    Topics: Adult; Colectomy; Colitis; Crohn Disease; Cystic Fibrosis; Gastrointestinal Hemorrhage; Humans; Inte

1986
Histochemical changes in gastric mucosubstances in patients with acute and chronic ulcer disease.
    Annals of surgery, 1974, Volume: 180, Issue:1

    Topics: Carboxylic Acids; Duodenal Ulcer; Epithelium; Esters; Gastric Mucosa; Gastritis; Gastrointestinal He

1974
Adenomas of the colon.
    The American journal of gastroenterology, 1968, Volume: 50, Issue:3

    Topics: Adenoma; Adult; Aged; Carcinoma; Colonic Neoplasms; Diarrhea; Electrosurgery; Female; Gastrointestin

1968
[Severe asthma. Study of 80 cases of severe and fatal asthma].
    Annales de medecine interne, 1969, Volume: 120, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti

1969
Aspirin gastritis examined with intragastric photography.
    IMS, Industrial medicine and surgery, 1969, Volume: 38, Issue:8

    Topics: Acetaminophen; Adult; Antacids; Aspirin; Buffers; Drug Hypersensitivity; Drug Synergism; Female; Gas

1969