guaifenesin has been researched along with Gastroesophageal Reflux in 20 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The underlying reflex mechanisms responsible for such swallows during apnea are unclear." | 3.67 | Pulmonary protective mechanisms in human infants. ( Menon, A; Thach, BT, 1985) |
| "Chronic cough is a common problem of various etiologies." | 2.79 | The assessment and management of chronic cough in children according to the British Thoracic Society guidelines: descriptive, prospective, clinical trial. ( Asilsoy, S; Durmaz, C; Usta Guc, B, 2014) |
| "Gastroesophageal reflux is common among patients with postnasal drainage." | 2.75 | Proton pump inhibitor therapy improves symptoms in postnasal drainage. ( Allocco, CT; Clement, LE; Duncavage, JA; Goutte, M; Hagaman, DD; Lanza, DC; McCafferty, BA; Slaughter, JC; Sparkman, C; Tanner, SB; Vaezi, MF; Wasden, CM; Wirth, D, 2010) |
| "However, there is a risk of gastroesophageal reflux associated with this technique." | 2.52 | Standard (head-down tilt) versus modified (without head-down tilt) postural drainage in infants and young children with cystic fibrosis. ( Chaves, GS; Dias, FA; Ferreira, GM; Freitas, DA; Guerra, RO; Mendonça, KM; Ribeiro, CT, 2015) |
| "Gastroesophageal reflux (GER), through the occurrence of gastroesophagopharyngeal reflux (GEPR), is an established cause of several otorhinolaryngological (ORL) manifestations." | 1.33 | The role of (duodeno)gastroesophagopharyngeal reflux in unexplained excessive throat phlegm. ( Feenstra, L; Poelmans, J; Tack, J, 2005) |
| "Cough was due to one condition in 73%, two in 23%, and three in 3%." | 1.28 | Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. ( Curley, FJ; French, CL; Irwin, RS, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Souza, TA | 1 |
| Carneiro, AP | 1 |
| Narciso, AS | 1 |
| Barros, CP | 1 |
| Alves, DA | 1 |
| Marson, LB | 1 |
| Tunala, T | 1 |
| de Alcântara, TM | 1 |
| de Paiva Maia, YC | 1 |
| Briza, P | 1 |
| Ferreira, F | 1 |
| Goulart, LR | 1 |
| Usta Guc, B | 1 |
| Asilsoy, S | 1 |
| Durmaz, C | 1 |
| Freitas, DA | 1 |
| Dias, FA | 1 |
| Chaves, GS | 1 |
| Ferreira, GM | 1 |
| Ribeiro, CT | 1 |
| Guerra, RO | 1 |
| Mendonça, KM | 1 |
| Robb-Nicholson, C | 1 |
| Vaezi, MF | 1 |
| Hagaman, DD | 1 |
| Slaughter, JC | 1 |
| Tanner, SB | 1 |
| Duncavage, JA | 1 |
| Allocco, CT | 1 |
| Sparkman, C | 1 |
| Clement, LE | 1 |
| Wasden, CM | 1 |
| Wirth, D | 1 |
| Goutte, M | 1 |
| McCafferty, BA | 1 |
| Lanza, DC | 1 |
| Morice, AH | 1 |
| Poelmans, J | 1 |
| Feenstra, L | 1 |
| Tack, J | 1 |
| O'Hara, J | 1 |
| Jones, NS | 1 |
| Beaver, ME | 1 |
| Stasney, CR | 1 |
| Rodriguez, M | 1 |
| Lang, IM | 1 |
| Haworth, ST | 1 |
| Medda, BK | 1 |
| Roerig, DL | 1 |
| Forster, HV | 1 |
| Shaker, R | 1 |
| Domschke, W | 1 |
| Schumpelick, V | 1 |
| Muers, MF | 1 |
| Olnes, SQ | 1 |
| Schwartz, RH | 1 |
| Bahadori, RS | 1 |
| Irwin, RS | 1 |
| Curley, FJ | 1 |
| French, CL | 1 |
| Orlando, RC | 1 |
| Siegel, SC | 1 |
| Rachelefsky, GS | 1 |
| Thach, BT | 1 |
| Menon, A | 1 |
| Kalm, O | 1 |
| Rundcrantz, H | 1 |
| Thiséus, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenotypic Characterization of Pediatric Patients With Esophageal Eosinophilia and Biomarkers Investigation for the Diagnosis of Eosinophilic Esophagitis[NCT03069573] | 110 participants (Actual) | Observational [Patient Registry] | 2015-01-01 | Completed | |||
| Assessment of Radio(Chemo)Therapy-related Dysphagia in Head and Neck Cancer Patients Based on Cough-related Acoustic Features[NCT05865756] | 40 participants (Anticipated) | Interventional | 2021-04-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for guaifenesin and Gastroesophageal Reflux
| Article | Year |
|---|---|
Standard (head-down tilt) versus modified (without head-down tilt) postural drainage in infants and young children with cystic fibrosis.
Topics: Anti-Bacterial Agents; Child, Preschool; Cystic Fibrosis; Disease Progression; Drainage, Postural; G | 2015 |
Post-nasal drip syndrome--a symptom to be sniffed at?
Topics: Asthma; Cough; Diagnosis, Differential; Gastroesophageal Reflux; Humans; Mucus; Nasal Cavity; Rhinit | 2004 |
The aetiology of chronic cough: a review of current theories for the otorhinolaryngologist.
Topics: Angiotensin-Converting Enzyme Inhibitors; Asthma; Bronchitis, Chronic; Chronic Disease; Cough; Eosin | 2005 |
[Stress ulcer: mechanisms of aggression and protection].
Topics: Animals; Epithelium; Gastric Acid; Gastric Mucosa; Gastroesophageal Reflux; Humans; Ischemia; Microc | 1983 |
Continuing medical education. Asthma in infants and children: Part 1.
Topics: Airway Resistance; Allergens; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Child, Pres | 1985 |
2 trials available for guaifenesin and Gastroesophageal Reflux
| Article | Year |
|---|---|
The assessment and management of chronic cough in children according to the British Thoracic Society guidelines: descriptive, prospective, clinical trial.
Topics: Adolescent; Asthma; Bronchitis; Child; Child, Preschool; Chronic Disease; Cough; Female; Gastroesoph | 2014 |
Proton pump inhibitor therapy improves symptoms in postnasal drainage.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Chronic Disease; Education, Medical, Continuing; Enz | 2010 |
13 other studies available for guaifenesin and Gastroesophageal Reflux
| Article | Year |
|---|---|
Eosinophilic esophagitis auxiliary diagnosis based on a peptide ligand to eosinophil cationic protein in esophageal mucus of pediatric patients.
Topics: Child; Chromatography, Liquid; Enteritis; Eosinophil Cationic Protein; Eosinophilia; Eosinophilic Es | 2022 |
Health tips. Stopping postnasal drip.
Topics: Allergens; Caffeine; Chronic Disease; Cough; Drinking; Gastroesophageal Reflux; Humans; Mucus; Nasal | 2013 |
By the way, doctor. I developed a hoarse voice and annoying phlegm in my throat and was surprised to learn that the cause was acid reflux. I've never had heartburn, so I don't know how this could have happened. Can you explain?
Topics: Esophagitis; Food Preferences; Gastroesophageal Reflux; Health Knowledge, Attitudes, Practice; Hoars | 2009 |
The role of (duodeno)gastroesophagopharyngeal reflux in unexplained excessive throat phlegm.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Color; Duodenogastric Reflux; Endoscopy | 2005 |
Mucus retention cyst and reflux disease.
Topics: Female; Gastroesophageal Reflux; Hoarseness; Humans; Middle Aged; Mucocele; Mucus; Proton Pump Inhib | 2005 |
Chronic cough. It can be helped.
Topics: Angiotensin-Converting Enzyme Inhibitors; Asthma; Chronic Disease; Cough; Gastroesophageal Reflux; H | 2006 |
Airway responses to esophageal acidification.
Topics: Airway Resistance; Animals; Bronchi; Cats; Disease Models, Animal; Esophagus; Female; Gastroesophage | 2008 |
Diurnal variation in asthma.
Topics: Airway Resistance; Asthma; Bronchodilator Agents; Circadian Rhythm; Epinephrine; Gastroesophageal Re | 1984 |
Consultation with the specialist: Diagnosis and management of the newborn and young infant who have nasal obstruction.
Topics: Choanal Atresia; Female; Gastroesophageal Reflux; Hamartoma; Humans; Infant; Infant, Newborn; Male; | 2000 |
Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchial Provocation Tests; Child; Chronic Dise | 1990 |
Esophageal epithelial resistance.
Topics: Bicarbonates; Epithelium; Esophagitis, Peptic; Esophagus; Gastroesophageal Reflux; Humans; Hydrogen- | 1986 |
Pulmonary protective mechanisms in human infants.
Topics: Apnea; Deglutition; Electromyography; Gastroesophageal Reflux; Humans; Infant, Newborn; Mucus; Pneum | 1985 |
[Back-nasal catarrh].
Topics: Esophagus; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Mucus; Nasal Mucosa; Nasopharynge | 1970 |