guaifenesin has been researched along with Fucosidosis in 1 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Fucosidosis: An autosomal recessive lysosomal storage disease caused by a deficiency of ALPHA-L-FUCOSIDASE activity resulting in an accumulation of fucose containing SPHINGOLIPIDS; GLYCOPROTEINS, and mucopolysaccharides (GLYCOSAMINOGLYCANS) in lysosomes. The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES, recurrent infections, and MACROGLOSSIA, with death occurring in the first decade of life. Juvenile fucosidosis (type II) is the more common variant and features a slowly progressive decline in neurologic function and angiokeratoma corporis diffusum. Type II survival may be through the fourth decade of life. (From Menkes, Textbook of Child Neurology, 5th ed, p87; Am J Med Genet 1991 Jan;38(1):111-31)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fucosidosis is caused by a deficiency of the lysosomal enzyme alpha-L-fucosidase (ALF) leading to an accumulation of glycoproteins in a variety of cells." | 1.28 | Recurrent respiratory infections in a child with fucosidosis: is the mucus too thin for effective transport? ( King, M; MacLeod, PM; Rubin, BK; Sturgess, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rubin, BK | 1 |
| MacLeod, PM | 1 |
| Sturgess, J | 1 |
| King, M | 1 |
1 other study available for guaifenesin and Fucosidosis
| Article | Year |
|---|---|
Recurrent respiratory infections in a child with fucosidosis: is the mucus too thin for effective transport?
Topics: Child; Child, Preschool; Ciliary Motility Disorders; Female; Fucosidosis; Humans; Lung; Mucociliary | 1991 |