guaifenesin and Eosinophilia, Tropical studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

Excerpt	Relevance	Reference
" In this study, we explored the suppressive effects of SAC on allergic airway inflammation induced in an ovalbumin (OVA)-induced asthma mouse model."	7.91	S-Allyl cysteine reduces eosinophilic airway inflammation and mucus overproduction on ovalbumin-induced allergic asthma model. ( Kim, JC; Kim, JS; Kim, SH; Ko, JW; Kwon, HJ; Lee, IC; Shin, IS; Shin, NR, 2019)
"We used ovalbumin (OVA)-based mouse models of asthma and primary CD4(+) T cells."	7.81	PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function. ( Al-Ghareeb, K; Al-Khami, AA; Boulares, AH; El-Bahrawy, AH; Ghonim, MA; Ibba, SV; Lammi, MR; Mansy, MS; Naura, AS; Ochoa, A; Pyakurel, K; Rady, HF; Ramsay, A; Rodriguez, P; Wang, J, 2015)
" In this study, we evaluated the protective effects of EBM84 on asthmatic responses, particularly mucus hypersecretion in an ovalbumin (OVA)-induced murine model of asthma."	7.79	EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma. ( Ha, H; Jeon, WY; Lee, MY; Seo, CS; Shin, IS; Shin, NR, 2013)
"Verapamil is a useful drug with therapeutic targeting on GCH and a potential way to limit mucous production and improve bronchial inflammation."	7.78	Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. ( Ghafarzadegan, K; Hadi, R; Khakzad, MR; Meshkat, M; Mirsadraee, M; Mohammadpour, A; Saghari, M, 2012)
" In this study, we explored the suppressive effects of SAC on allergic airway inflammation induced in an ovalbumin (OVA)-induced asthma mouse model."	3.91	S-Allyl cysteine reduces eosinophilic airway inflammation and mucus overproduction on ovalbumin-induced allergic asthma model. ( Kim, JC; Kim, JS; Kim, SH; Ko, JW; Kwon, HJ; Lee, IC; Shin, IS; Shin, NR, 2019)
" PRE treatment decreased mucus production in airway epithelium, inflammatory cell number, eosinophilia, type 2 cytokines, and histamine in bronchoalveolar lavage fluid (BALF)."	3.85	Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation. ( Chun, JM; Gu, GJ; Kim, HS; Kwon, BI; Lee, AR; Lee, AY, 2017)
"We used ovalbumin (OVA)-based mouse models of asthma and primary CD4(+) T cells."	3.81	PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function. ( Al-Ghareeb, K; Al-Khami, AA; Boulares, AH; El-Bahrawy, AH; Ghonim, MA; Ibba, SV; Lammi, MR; Mansy, MS; Naura, AS; Ochoa, A; Pyakurel, K; Rady, HF; Ramsay, A; Rodriguez, P; Wang, J, 2015)
" In this study, we evaluated the protective effects of EBM84 on asthmatic responses, particularly mucus hypersecretion in an ovalbumin (OVA)-induced murine model of asthma."	3.79	EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma. ( Ha, H; Jeon, WY; Lee, MY; Seo, CS; Shin, IS; Shin, NR, 2013)
"Verapamil is a useful drug with therapeutic targeting on GCH and a potential way to limit mucous production and improve bronchial inflammation."	3.78	Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. ( Ghafarzadegan, K; Hadi, R; Khakzad, MR; Meshkat, M; Mirsadraee, M; Mohammadpour, A; Saghari, M, 2012)
"In the present study, we investigated whether the Lagerstroemia indica Linn (LI) extract has an anti-inflammatory effect on lung inflammation in ovalbumin-induced asthmatic mice."	3.77	Anti-inflammatory effects of ethanolic extract from Lagerstroemia indica on airway inflammation in mice. ( Kim, DH; Kim, IS; Lee, JS; Song, BB; Yang, EJ; Yun, CY, 2011)
" Becker (VM) ethanolic (EtOH) extract in the treatment of bronchial asthma in an ovalbumin (OVA)-induced asthmatic BALB/c mouse model."	3.76	Anti-inflammatory and anti-asthmatic effects of Viola mandshurica W. Becker (VM) ethanolic (EtOH) extract on airway inflammation in a mouse model of allergic asthma. ( Ahn, KS; Kim, HS; Kwon, OK; Lee, HK; Lee, MY; Oh, SR; Yuk, JE, 2010)
" The data showed that chronic SJ infection suppressed airway eosinophilia, mucus production and antigen-specific IgE responses induced by ovalbumin (OVA) sensitization and challenge."	3.76	Helminth infection inhibits airway allergic reaction and dendritic cells are involved in the modulation process. ( An, G; Gao, W; Ji, W; Li, J; Liu, P; Liu, X; Shen, Y; Wang, S; Wu, Z; Yang, X; Zhu, Y, 2010)
" In order to investigate the pharmacological effects of kefir, we used a mouse asthma model, in which airway inflammation and airway remodeling was produced by ovalbumin sensitization and challenge."	3.74	Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model. ( Ahn, KS; Kim, MJ; Kim, MK; Kwon, OK; Lee, HK; Lee, IY; Lee, MY; Oh, SR, 2007)
"An asthma model was sensitized and challenged by ovalbumin (OVA) in male C57BL/6 mice."	3.73	CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma. ( Shen, HH; Wang, SB; Xu, F; Xu, WH; Zhang, GS, 2006)
" The current study demonstrates that, in contrast to naive mice, T helper 2 bias, airways hyperreactivity (AHR) and tissue eosinophilia develop in Ovalbumin-sensitized IL-4Ralpha(-/-) mice and that these responses can be inhibited by the IL-13 antagonist sIL-13Ralpha2Fc."	3.72	Antigen-specific production of interleukin (IL)-13 and IL-5 cooperate to mediate IL-4Ralpha-independent airway hyperreactivity. ( Cai, Y; Donaldson, DD; Foster, PS; Mahalingam, S; Matthaei, KI; Webb, DC, 2003)
"A chronic obstructive sialadenitis symptom (COSS) questionnaire was used to quantify the treatment outcomes."	1.62	Allergy-Related Sialodochitis: A Preliminary Cohort Study. ( Chen, Y; Liu, DG; Yu, GY; Zhang, LQ; Zhang, YQ; Zhao, YN, 2021)
"Mucus plugs are a plausible mechanism of chronic airflow obstruction in severe asthma, and EPO-generated oxidants may mediate mucus plug formation."	1.48	Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. ( Bleecker, ER; Castro, M; Di Maio, S; Dunican, EM; Elicker, BM; Erzurum, SC; Fahy, JV; Fain, SB; Gierada, DS; Gordon, ED; Hoffman, EA; Israel, E; Jarjour, NN; Lachowicz-Scroggins, ME; Levy, BD; Mauger, DT; Meyers, DA; Nagle, SK; Newell, JD; Peters, MC; Phillips, BR; Raymond, WW; Schiebler, ML; Wenzel, SE; Woodruff, PG, 2018)
"Allergic rhinitis is a chronic inflammatory disease orchestrated by Th2 lymphocytes."	1.40	Regulation of nasal airway homeostasis and inflammation in mice by SHP-1 and Th2/Th1 signaling pathways. ( Cho, SH; Lane, AP; Lee, J; Lee, S; Oh, MH; Oh, SY; Zheng, T; Zhu, Z, 2014)
"Chronic eosinophilic pneumonia is a rare cause of chronic lung disease in children."	1.36	Chronic eosinophilic pneumonia with mucous plugs in a child. ( Aksoy, F; Cakir, E; Cakır, FB; Ertem, T, 2010)
"Interestingly, pulmonary fibrosis observed in wild-type mice under the chronic protocol was completely absent in iNOS(-/-) mice despite persistent IL-5 and IL-13 production, suggesting that these cytokines were insufficient for pulmonary fibrosis."	1.36	Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation. ( Abd Elmageed, ZY; Boulares, AH; Errami, Y; Hans, CP; Ju, J; Kim, H; Naura, AS; Ochoa, AC; Park, J; Rodriguez, PC; Zerfaoui, M, 2010)
"When fasudil was administrated to OVA-challenged mice, increased cell numbers of total cells and eosinophils were significantly attenuated in a dose-dependent manner."	1.34	Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges. ( Aratake, H; Kobayashi, T; Kume, H; Ohta, H; Shimokata, K; Taki, F, 2007)
"To evaluate lung inflammation, mucus metaplasia and AHR in relationship with age in murine models of allergic asthma comparing young and older mice."	1.34	Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. ( Busse, PJ; Li, XM; Schofield, B; Srivastava, K; Zhang, TF, 2007)
"Airway eosinophilia was observed during both responses."	1.33	Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma. ( Arakawa, H; Koyama, H; Mayuzumi, H; Mizuno, T; Mochizuki, H; Morikawa, A; Nishimura, H; Ohki, Y; Tokuyama, K, 2005)
"Eosinophilia was abolished, yet mucus staining in the epithelium persisted."	1.30	Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. ( Bottomly, K; Brombacher, F; Cohn, L; Homer, RJ; MacLeod, H; Mohrs, M, 1999)
"Eosinophilia was associated with asthma and with phlegm production."	1.28	Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study. ( O'Connor, GT; Sparrow, D; Tollerud, DJ; Weiss, ST, 1991)

Research

Studies (66)

Authors

Clinical Trials (12)

Trial Overview

Trial Outcomes

Number of Participants With Dose Limiting Toxicity

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (12.12)	18.7374
1990's	9 (13.64)	18.2507
2000's	30 (45.45)	29.6817
2010's	17 (25.76)	24.3611
2020's	2 (3.03)	2.80

Authors	Studies
de Souza, TA	1
Carneiro, AP	1
Narciso, AS	1
Barros, CP	1
Alves, DA	1
Marson, LB	1
Tunala, T	1
de Alcântara, TM	1
de Paiva Maia, YC	1
Briza, P	1
Ferreira, F	1
Goulart, LR	1
Zhao, YN	1
Zhang, LQ	1
Zhang, YQ	1
Chen, Y	1
Liu, DG	1
Yu, GY	1
Toki, S	1
Goleniewska, K	2
Reiss, S	1
Zhang, J	1
Bloodworth, MH	1
Stier, MT	1
Zhou, W	2
Newcomb, DC	1
Ware, LB	1
Stanwood, GD	1
Galli, A	1
Boyd, KL	1
Niswender, KD	1
Peebles, RS	2
Georas, SN	1
Dunican, EM	1
Elicker, BM	1
Gierada, DS	1
Nagle, SK	1
Schiebler, ML	1
Newell, JD	1
Raymond, WW	1
Lachowicz-Scroggins, ME	1
Di Maio, S	1
Hoffman, EA	1
Castro, M	1
Fain, SB	1
Jarjour, NN	1
Israel, E	1
Levy, BD	1
Erzurum, SC	1
Wenzel, SE	1
Meyers, DA	1
Bleecker, ER	1
Phillips, BR	1
Mauger, DT	1
Gordon, ED	1
Woodruff, PG	1
Peters, MC	1
Fahy, JV	1
Shin, NR	2
Kwon, HJ	1
Ko, JW	1
Kim, JS	1
Lee, IC	1
Kim, JC	1
Kim, SH	1
Shin, IS	2
Lee, MY	3
Jeon, WY	1
Seo, CS	1
Ha, H	1
Guimond, DM	1
Cam, NR	1
Hirve, N	1
Duan, W	1
Lambris, JD	1
Croft, M	2
Tsoukas, CD	1
Cowie, RH	1
Cho, SH	1
Oh, SY	1
Lane, AP	1
Lee, J	1
Oh, MH	1
Lee, S	1
Zheng, T	1
Zhu, Z	1
Ghonim, MA	1
Pyakurel, K	1
Ibba, SV	1
Al-Khami, AA	1
Wang, J	1
Rodriguez, P	1
Rady, HF	1
El-Bahrawy, AH	1
Lammi, MR	1
Mansy, MS	1
Al-Ghareeb, K	1
Ramsay, A	1
Ochoa, A	1
Naura, AS	2
Boulares, AH	2
Lee, AR	1
Chun, JM	1
Lee, AY	1
Kim, HS	2
Gu, GJ	1
Kwon, BI	1
Lee, M	1
Kim, S	1
Kwon, OK	3
Oh, SR	3
Lee, HK	4
Ahn, K	1
Pignatti, P	1
Pala, G	1
Pisati, M	1
Perfetti, L	1
Banchieri, G	1
Moscato, G	1
Song, DJ	2
Cho, JY	2
Lee, SY	1
Miller, M	2
Rosenthal, P	1
Soroosh, P	1
Zhang, M	1
Varki, A	1
Broide, DH	2
Yuk, JE	1
Ahn, KS	2
Liu, P	1
Li, J	1
Yang, X	4
Shen, Y	1
Zhu, Y	1
Wang, S	3
Wu, Z	1
Liu, X	1
An, G	1
Ji, W	1
Gao, W	1
Yang, EJ	1
Lee, JS	1
Song, BB	1
Yun, CY	1
Kim, DH	1
Kim, IS	1
Cakir, E	1
Aksoy, F	1
Cakır, FB	1
Ertem, T	1
Zerfaoui, M	1
Kim, H	1
Abd Elmageed, ZY	1
Rodriguez, PC	1
Hans, CP	1
Ju, J	1
Errami, Y	1
Park, J	1
Ochoa, AC	1
Khakzad, MR	1
Mirsadraee, M	1
Mohammadpour, A	1
Ghafarzadegan, K	1
Hadi, R	1
Saghari, M	1
Meshkat, M	1
Tesfaigzi, Y	1
Fischer, MJ	1
Daheshia, M	1
Green, FH	1
De Sanctis, GT	1
Wilder, JA	1
Kibe, A	1
Inoue, H	1
Fukuyama, S	1
Machida, K	1
Matsumoto, K	1
Koto, H	1
Ikegami, T	1
Aizawa, H	1
Hara, N	1
Advenier, D	1
Guichard, Ch	1
Kémény, JL	1
Tridon, A	1
Gilain, L	1
Braun, H	2
Buzina, W	2
Freudenschuss, K	2
Beham, A	2
Stammberger, H	2
Jeffery, P	1
Zhu, J	1
Lackner, A	1
ALBERICI, RA	2
Webb, DC	1
Mahalingam, S	1
Cai, Y	1
Matthaei, KI	1
Donaldson, DD	1
Foster, PS	1
Wills-Karp, M	2
Kelly-Welch, AE	1
Melo, ME	1
Smith, E	1
Ford, AQ	1
Haudenschild, C	1
Noben-Trauth, N	1
Keegan, AD	1
Hoshino, A	1
Tsuji, T	1
Matsuzaki, J	1
Jinushi, T	1
Ashino, S	1
Teramura, T	1
Chamoto, K	1
Tanaka, Y	1
Asakura, Y	1
Sakurai, T	1
Mita, Y	1
Takaoka, A	1
Nakaike, S	1
Takeshima, T	1
Ikeda, H	1
Nishimura, T	1
Bernstein, JM	1
Kansal, R	1
Ohki, Y	2
Tokuyama, K	2
Mayuzumi, H	2
Sato, A	1
Koyama, H	2
Takizawa, T	1
Arakawa, H	2
Mochizuki, H	2
Morikawa, A	2
Hashimoto, K	1
Durbin, JE	1
Collins, RD	1
Ho, SB	1
Kolls, JK	1
Dubin, PJ	1
Sheller, JR	1
O'Neal, JF	1
Olson, SJ	1
Mitchell, D	1
Graham, BS	1
O'Hara, J	1
Jones, NS	1
Nishimura, H	1
Mizuno, T	1
Lee, KS	1
Hayflick, JS	1
Lee, YC	1
Puri, KD	1
Han, X	2
Fan, Y	2
Yang, J	2
Jiao, L	1
Qiu, H	1
Pant, H	1
Kette, FE	1
Smith, WB	1
Macardle, PJ	1
Wormald, PJ	2
Shen, HH	1
Xu, F	1
Zhang, GS	1
Wang, SB	1
Xu, WH	1
Ooi, EH	1
Carney, AS	1
James, CL	1
Tan, LW	1
Min, MG	1
McElwain, S	1
Ferguson, P	1
Taki, F	1
Kume, H	1
Kobayashi, T	1
Ohta, H	1
Aratake, H	1
Shimokata, K	1
Bevelander, M	1
Mayette, J	1
Whittaker, LA	1
Paveglio, SA	1
Jones, CC	1
Robbins, J	1
Hemenway, D	1
Akira, S	1
Uematsu, S	1
Poynter, ME	1
Busse, PJ	1
Zhang, TF	1
Srivastava, K	1
Schofield, B	2
Li, XM	1
Kim, MJ	1
Kim, MK	1
Lee, IY	1
Okuda, M	1
Miura, I	1
Juji, F	1
Takashima, H	1
Kuperman, D	1
Grusby, MJ	1
Vezza, PR	1
Montgomery, EA	1
Cohn, L	3
Homer, RJ	2
MacLeod, H	1
Mohrs, M	1
Brombacher, F	1
Bottomly, K	2
Niu, N	1
Clarke, AH	1
Thomas, WR	1
Rolland, JM	1
Dow, C	1
O'Brien, RM	1
Zhang, DH	1
Yang, L	1
Parkyn, L	1
Homer, R	1
Ray, P	1
Ray, A	1
Wu, CA	1
Puddington, L	1
Whiteley, HE	1
Yiamouyiannis, CA	1
Schramm, CM	1
Mohammadu, F	1
Thrall, RS	1
Bilenki, L	1
McMillan, SJ	1
Bishop, B	1
Townsend, MJ	1
McKenzie, AN	1
Lloyd, CM	1
Blair, H	1
Viner, AS	1
Hoff, VP	1
Vick, U	1
Tollerud, DJ	1
O'Connor, GT	1
Sparrow, D	1
Weiss, ST	1
Miszke, A	1
Sanokowska, E	1
Markiewicz, J	1
Colldahl, H	1
Dahlgren, SE	1
Orell, S	1
Salvato, G	1
Miller, WF	1
Johnston, FF	1
Tarkoff, MP	1
Williams, RB	1
Gwaltney, JM	1
Sanerkin, NG	1
Seal, RM	1
Leopold, JG	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Phenotypic Characterization of Pediatric Patients With Esophageal Eosinophilia and Biomarkers Investigation for the Diagnosis of Eosinophilic Esophagitis[NCT03069573]		110 participants (Actual)	Observational [Patient Registry]	2015-01-01	Completed
Severe Asthma Research Program (SARP) - University of Wisconsin[NCT01760915]		107 participants (Actual)	Observational	2012-11-28	Completed
Clinical and Molecular Phenotypes of Severe Asthma[NCT01718197]		151 participants (Actual)	Observational	2012-11-30	Completed
A Two-arm, Placebo-controlled, Randomized Clinical Trial to Evaluate the Effect of Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe Asthma[NCT05280418]	Phase 3	30 participants (Anticipated)	Interventional	2022-11-08	Recruiting
Severe Asthma Research Program[NCT01606826]		1,100 participants (Anticipated)	Observational	2012-10-31	Active, not recruiting
Severe Asthma Research Program[NCT01759186]		300 participants (Anticipated)	Observational	2012-12-31	Active, not recruiting
Severe Asthma Research Program (SARP)-Washington University[NCT01716494]		121 participants (Actual)	Observational	2012-10-31	Active, not recruiting
The Severe Asthma Research Program at Wake Forest University - Longitudinal Phenomics and Genetics of Severe Asthma.[NCT01750411]		87 participants (Actual)	Observational	2012-12-31	Completed
ALXR/FPR Mediated Signaling in Severe Asthma (AMSA)-The Severe Asthma Research Program (SARP) III[NCT01761630]		126 participants (Actual)	Observational	2012-12-31	Completed
Phase Ib/II Clinical Trial of Topical Verapamil Hydrochloride for Chronic Rhinosinusitis With Nasal Polyps[NCT03102190]	Phase 1	6 participants (Actual)	Interventional	2017-06-05	Terminated (stopped due to Phase II funding not available)
Randomized Double Blind Placebo Controlled Trial of Verapamil in Chronic Rhinosinusitis[NCT02454608]		29 participants (Actual)	Interventional	2015-05-31	Terminated (stopped due to Evidence that the dose is insufficient.)
[NCT00005284]		0 participants	Observational	1985-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Dose Limiting Toxicity will be defined as a development of 2nd or 3rd degree heart block as measured by an EKG. (Phase Ib primary outcome) (NCT03102190)
Timeframe: 1-8 weeks

Diastolic Blood Pressure

Heart Rate

Objective Sinonasal Symptoms on Lund-Kennedy Score(LKS)

Intervention	Participants (Count of Participants)
Phase Ib	0

Intervention	mmHg (Mean)
Treatment	-0.6
Control	1

Intervention	beats per minute (Mean)
Treatment	-1.4
Control	4

Minimum Score: 0 Maximum Score: 12 Higher value represents worse outcome. (NCT02454608)
Timeframe: baseline to week 8

Objective Sinonasal Symptoms on Lund-McKay Score(LMS)

Intervention	units on a scale (Least Squares Mean)
Treatment	-1.3
Control	-0.25

Minimum Score: 0 Maximum Score: 24 Higher value represents worse outcome. (NCT02454608)
Timeframe: Week 8

Subjective Sinonasal Symptoms on 10cm Visual Analogue Scale(VAS)

Intervention	units on a scale (Mean)
Treatment	12.5
Control	17.7

Minimum Score: 0 Maximum Score: 100 A higher score indicates a worse outcome. (NCT02454608)
Timeframe: baseline to week 8

Subjective Sinonasal Symptoms on Sinonasal Outcomes Test-22(SNOT-22)

Intervention	units on a scale (Least Squares Mean)
Treatment	-44.03
Control	-6.07

Minimum Score: 0 Maximum Score: 110 A higher score indicates a worse outcome (NCT02454608)
Timeframe: baseline to week 8

Systolic Blood Pressure

Subjective Sinonasal Symptoms on 10cm Visual Analogue Scale(VAS)

Intervention	units on a scale (Least Squares Mean)
Treatment	-27.3
Control	0.4

Intervention	mmHg (Mean)
Treatment	-4.5
Control	-6.6

Minimum Score: 0 Maximum Score: 100 A higher score indicates a worse outcome. (NCT02454608)
Timeframe: baseline to week 56

Subjective Sinonasal Symptoms on Sinonasal Outcomes Test-22(SNOT-22)

Intervention	units on a scale (Mean)
	Medicine Completers, baseline	Medicine Completers, week 56	Surgical Completers, baseline	Surgical Completers, week 12
Open Label	64.3	35.0	90.0	16.7

Minimum Score: 0 Maximum Score: 110 A higher score indicates a worse outcome (NCT02454608)
Timeframe: baseline to week 56

Article	Year
Pathways for transmission of angiostrongyliasis and the risk of disease associated with them. Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health, 2013, Volume: 72, Issue:6 Suppl 2 Topics: Angiostrongylus cantonensis; Animals; Anura; Brachyura; Cooking; Eosinophilia; Food Parasitology; Hu	2013
Mucin-producing elements and inflammatory cells. Novartis Foundation symposium, 2002, Volume: 248 Topics: Animals; Arachidonic Acids; Bronchitis; Cytokines; Eosinophilia; Exocrine Glands; Exocytosis; Goblet	2002
Interleukin-13 in asthma pathogenesis. Current allergy and asthma reports, 2004, Volume: 4, Issue:2 Topics: Asthma; Eosinophilia; Epithelial Cells; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subun	2004
The aetiology of chronic cough: a review of current theories for the otorhinolaryngologist. The Journal of laryngology and otology, 2005, Volume: 119, Issue:7 Topics: Angiotensin-Converting Enzyme Inhibitors; Asthma; Bronchitis, Chronic; Chronic Disease; Cough; Eosin	2005

Article	Year
Eosinophilic esophagitis auxiliary diagnosis based on a peptide ligand to eosinophil cationic protein in esophageal mucus of pediatric patients. Scientific reports, 2022, 07-18, Volume: 12, Issue:1 Topics: Child; Chromatography, Liquid; Enteritis; Eosinophil Cationic Protein; Eosinophilia; Eosinophilic Es	2022
Allergy-Related Sialodochitis: A Preliminary Cohort Study. The Laryngoscope, 2021, Volume: 131, Issue:9 Topics: Adult; Aged; Biopsy; Case-Control Studies; Chronic Disease; Cohort Studies; Endoscopy; Eosinophilia;	2021
Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell cytokine production in vivo. The Journal of allergy and clinical immunology, 2018, Volume: 142, Issue:5 Topics: Allergens; Alternaria; Animals; Asthma; Cytokines; Dermatophagoides pteronyssinus; Eosinophilia; Fem	2018
All plugged up - noninvasive mucus score to assess airway dysfunction in asthma. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Asthma; Eosinophilia; Humans; Lung; Mucus	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. The Journal of clinical investigation, 2018, 03-01, Volume: 128, Issue:3 Topics: Adult; Asthma; Case-Control Studies; Cysteine; Elasticity; Eosinophil Peroxidase; Eosinophilia; Fema	2018
S-Allyl cysteine reduces eosinophilic airway inflammation and mucus overproduction on ovalbumin-induced allergic asthma model. International immunopharmacology, 2019, Volume: 68 Topics: Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage	2019
EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma. International journal of molecular medicine, 2013, Volume: 31, Issue:4 Topics: Analysis of Variance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophilia; Female	2013
Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide. PloS one, 2013, Volume: 8, Issue:5 Topics: Amino Acid Sequence; Animals; Bronchial Hyperreactivity; Bronchioles; Cell-Penetrating Peptides; Cyt	2013
Regulation of nasal airway homeostasis and inflammation in mice by SHP-1 and Th2/Th1 signaling pathways. PloS one, 2014, Volume: 9, Issue:8 Topics: Animals; Chemokines; Eosinophilia; Gelatin; Homeostasis; Inflammation; Interferon-gamma; Matrix Meta	2014
PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function. Journal of translational medicine, 2015, Jul-14, Volume: 13 Topics: Adoptive Transfer; Animals; Antigens, CD; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocy	2015
Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation. Journal of ethnopharmacology, 2017, Jan-20, Volume: 196 Topics: Allergens; Animals; Anti-Asthmatic Agents; Apiaceae; Asthma; Bronchoalveolar Lavage Fluid; CD4-Posit	2017
Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma. International immunopharmacology, 2009, Volume: 9, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lav	2009
Nasal blown secretion evaluation in specific occupational nasal challenges. International archives of occupational and environmental health, 2010, Volume: 83, Issue:2 Topics: Adolescent; Adult; Aged; Case-Control Studies; Eosinophilia; Eosinophils; Humans; Immunologic Tests;	2010
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. Journal of immunology (Baltimore, Md. : 1950), 2009, Oct-15, Volume: 183, Issue:8 Topics: Allergens; Animals; Antibodies, Monoclonal; Antigens, Differentiation, Myelomonocytic; Apoptosis; Eo	2009
Anti-inflammatory and anti-asthmatic effects of Viola mandshurica W. Becker (VM) ethanolic (EtOH) extract on airway inflammation in a mouse model of allergic asthma. Journal of ethnopharmacology, 2010, Jan-08, Volume: 127, Issue:1 Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchi; Bronchial	2010
Helminth infection inhibits airway allergic reaction and dendritic cells are involved in the modulation process. Parasite immunology, 2010, Volume: 32, Issue:1 Topics: Adoptive Transfer; Animals; Asthma; Bronchial Hyperreactivity; Dendritic Cells; Eosinophilia; Female	2010
Anti-inflammatory effects of ethanolic extract from Lagerstroemia indica on airway inflammation in mice. Journal of ethnopharmacology, 2011, Jul-14, Volume: 136, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cytokines; Eosin	2011
Chronic eosinophilic pneumonia with mucous plugs in a child. Pediatric pulmonology, 2010, Volume: 45, Issue:10 Topics: Bronchoscopy; Child; Eosinophilia; Female; Humans; Mucus; Pulmonary Eosinophilia	2010
Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation. Journal of immunology (Baltimore, Md. : 1950), 2010, Sep-01, Volume: 185, Issue:5 Topics: Acute Disease; Allergens; Animals; Cells, Cultured; Chickens; Eosinophilia; Gene Deletion; Inflammat	2010
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:2 Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An	2012
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:2 Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An	2012
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:2 Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An	2012
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals. Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:2 Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, An	2012
Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia. Journal of immunology (Baltimore, Md. : 1950), 2002, Nov-15, Volume: 169, Issue:10 Topics: Allergens; Animals; bcl-2-Associated X Protein; Bronchi; Cell Count; Culture Techniques; Dissection;	2002
Differential regulation by glucocorticoid of interleukin-13-induced eosinophilia, hyperresponsiveness, and goblet cell hyperplasia in mouse airways. American journal of respiratory and critical care medicine, 2003, Jan-01, Volume: 167, Issue:1 Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemokine CCL11; Chemokines, CC; Dexamethasone; E	2003
[Analysis of eosinophilia and ECP levels in blood and nasal secretions of 119 nasal polyposis patients]. Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 2002, Volume: 119, Issue:6 Topics: Adult; Blood Proteins; Eosinophil Granule Proteins; Eosinophilia; Female; Humans; Male; Middle Aged;	2002
'Eosinophilic fungal rhinosinusitis': a common disorder in Europe? The Laryngoscope, 2003, Volume: 113, Issue:2 Topics: Chronic Disease; Eosinophilia; Eosinophils; Fungi; Humans; Mucus; Mycoses; Nasal Cavity; Nasal Mucos	2003
[Incidence and detection of fungi and eosinophilic granulocytes in chronic rhinosinusitis]. Laryngo- rhino- otologie, 2003, Volume: 82, Issue:5 Topics: Chronic Disease; Colony Count, Microbial; Diagnosis, Differential; Eosinophilia; Eosinophils; Fungi;	2003
[Mucous plugs of the bronchis in patients with asthma and Hoffman and Teichmuller's eosinophilic catarrh]. El Dia medico, 1956, Sep-10, Volume: 28, Issue:65 Topics: Asthma; Bronchi; Bronchial Diseases; Common Cold; Disease; Eosinophilia; Humans; Mucus	1956
[Mucous plugs of the bronchis in patients with asthma and Hoffman and Teichmuller's eosinophilic catarrh]. El Dia medico, 1956, Sep-10, Volume: 28, Issue:65 Topics: Asthma; Bronchi; Bronchial Diseases; Common Cold; Disease; Eosinophilia; Humans; Mucus	1956
[Mucous plugs of the bronchis in patients with asthma and Hoffman and Teichmuller's eosinophilic catarrh]. El Dia medico, 1956, Sep-10, Volume: 28, Issue:65 Topics: Asthma; Bronchi; Bronchial Diseases; Common Cold; Disease; Eosinophilia; Humans; Mucus	1956
[Mucous plugs of the bronchis in patients with asthma and Hoffman and Teichmuller's eosinophilic catarrh]. El Dia medico, 1956, Sep-10, Volume: 28, Issue:65 Topics: Asthma; Bronchi; Bronchial Diseases; Common Cold; Disease; Eosinophilia; Humans; Mucus	1956
Antigen-specific production of interleukin (IL)-13 and IL-5 cooperate to mediate IL-4Ralpha-independent airway hyperreactivity. European journal of immunology, 2003, Volume: 33, Issue:12 Topics: Animals; Bronchial Hyperreactivity; Eosinophilia; Interferon-gamma; Interleukin-13; Interleukin-13 R	2003
Complex role of the IL-4 receptor alpha in a murine model of airway inflammation: expression of the IL-4 receptor alpha on nonlymphoid cells of bone marrow origin contributes to severity of inflammation. Journal of immunology (Baltimore, Md. : 1950), 2004, Apr-01, Volume: 172, Issue:7 Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Disease Model	2004
STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation. International immunology, 2004, Volume: 16, Issue:10 Topics: Administration, Intranasal; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid	2004
Superantigen hypothesis for the early development of chronic hyperplastic sinusitis with massive nasal polyposis. Current opinion in otolaryngology & head and neck surgery, 2005, Volume: 13, Issue:1 Topics: Bacterial Toxins; Chronic Disease; Enterotoxins; Eosinophilia; Humans; Hyperplasia; Lymphocytes; Muc	2005
Characteristic features of allergic airway inflammation in a murine model of infantile asthma. International archives of allergy and immunology, 2005, Volume: 138, Issue:1 Topics: Age Factors; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Di	2005
Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels. The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:3 Topics: Animals; Blotting, Western; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chloride Channe	2005
Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma. International archives of allergy and immunology, 2005, Volume: 138, Issue:3 Topics: Airway Obstruction; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchoalveolar Lavage Fluid;	2005
Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3 Topics: Adenine; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar La	2006
Chlamydia infection induces ICOS ligand-expressing and IL-10-producing dendritic cells that can inhibit airway inflammation and mucus overproduction elicited by allergen challenge in BALB/c mice. Journal of immunology (Baltimore, Md. : 1950), 2006, May-01, Volume: 176, Issue:9 Topics: Allergens; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Separation; Cells, Cultur	2006
Eosinophilic mucus chronic rhinosinusitis: clinical subgroups or a homogeneous pathogenic entity? The Laryngoscope, 2006, Volume: 116, Issue:7 Topics: Adult; Aged; Antibodies, Fungal; Chronic Disease; Diagnosis, Differential; Eosinophilia; Female; Fol	2006
CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma. Acta pharmacologica Sinica, 2006, Volume: 27, Issue:12 Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchoalveolar Lavage Fluid; Eosinophilia; Eosinophils; Er	2006
Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and alternaria in a nasal explant model. The Laryngoscope, 2007, Volume: 117, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Allergens; Alternaria; Aspergillus fumigatus; Eosinophilia; Female;	2007
Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice. Journal of immunology (Baltimore, Md. : 1950), 2007, Apr-15, Volume: 178, Issue:8 Topics: Actins; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Chemokine CCL11; Chemokines,	2007
Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allergens; Animals; Bronchial Hyperreactivity; Bronch	2007
Nitrogen dioxide promotes allergic sensitization to inhaled antigen. Journal of immunology (Baltimore, Md. : 1950), 2007, Sep-15, Volume: 179, Issue:6 Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Bronchial Hyperreactivity; Eosinophilia; I	2007
Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:9 Topics: Aging; Animals; Asthma; B-Lymphocytes; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Enzy	2007
Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model. Immunobiology, 2007, Volume: 212, Issue:8 Topics: Administration, Oral; Animals; Asthma; Bronchial Hyperreactivity; Cultured Milk Products; Cytokines;	2007
A novel method of counting eosinophils in nasal secretion of allergic rhinitis by hemocytometric method. International archives of allergy and immunology, 1994, Volume: 104 Suppl 1, Issue:1 Topics: Adult; Blood Cell Count; Eosinophilia; Eosinophils; Humans; Leukocyte Count; Mucins; Mucus; Nasal Mu	1994
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. The Journal of experimental medicine, 1998, Mar-16, Volume: 187, Issue:6 Topics: Animals; Antigens; Bronchial Hyperreactivity; Eosinophilia; Female; Immunoglobulin E; Immunoglobulin	1998
Images in clinical medicine. Curschmann's spirals. The New England journal of medicine, 1998, Oct-08, Volume: 339, Issue:15 Topics: Aged; Bronchoalveolar Lavage Fluid; Eosinophilia; Female; Humans; Mucus; Pneumonia	1998
Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. Journal of immunology (Baltimore, Md. : 1950), 1999, May-15, Volume: 162, Issue:10 Topics: Administration, Inhalation; Animals; Asthma; Bronchi; Eosinophilia; Eosinophils; Interleukin-13 Rece	1999
T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production. The Journal of experimental medicine, 1999, Nov-01, Volume: 190, Issue:9 Topics: Animals; Asthma; Disease Models, Animal; Eosinophilia; Flow Cytometry; Hypersensitivity; Inflammatio	1999
Murine allergic respiratory responses to the major house dust mite allergen Der p 1. International archives of allergy and immunology, 1999, Volume: 120, Issue:2 Topics: Allergens; Animals; Antibodies, Anti-Idiotypic; Antibody Specificity; Antigens, Dermatophagoides; Do	1999
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3. Immunity, 1999, Volume: 11, Issue:4 Topics: Aerosols; Amino Acid Substitution; Animals; Asthma; Bronchoalveolar Lavage Fluid; DNA-Binding Protei	1999
Murine cytomegalovirus infection alters Th1/Th2 cytokine expression, decreases airway eosinophilia, and enhances mucus production in allergic airway disease. Journal of immunology (Baltimore, Md. : 1950), 2001, Sep-01, Volume: 167, Issue:5 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Cytomegalovirus Infections; Disease Models	2001
Chlamydia trachomatis infection inhibits airway eosinophilic inflammation induced by ragweed. Clinical immunology (Orlando, Fla.), 2002, Volume: 102, Issue:1 Topics: Allergens; Animals; Asteraceae; Chemokines; Chlamydia Infections; Chlamydia trachomatis; Cytokines;	2002
The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity. The Journal of experimental medicine, 2002, Jan-07, Volume: 195, Issue:1 Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemokine CCL11; Chemokines, CC; Eosinophilia; Go	2002
[The value of eosinophilia in the diagnosis of allergic otitis media]. Zeitschrift fur arztliche Fortbildung, 1975, Mar-01, Volume: 69, Issue:5 Topics: Eosinophilia; Humans; Hypersensitivity; Leukocyte Count; Mucus; Nasal Mucosa; Otitis Media; Suppurat	1975
Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study. The American review of respiratory disease, 1991, Volume: 144, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Aging; Asthma; Eosinophilia; Humans; Hypersensitivity; Immunoglobuli	1991
[Eosinophilic non-allergic rhinitis. Clinical and cytological evaluation]. Otolaryngologia polska = The Polish otolaryngology, 1991, Volume: 45, Issue:2 Topics: Adolescent; Adult; Aged; Eosinophilia; Eosinophils; Female; Humans; Leukocyte Count; Male; Middle Ag	1991
Deaths in primary asthma with special reference to pathology. Acta allergologica, 1971, Volume: 26, Issue:6 Topics: Adolescent; Adult; Aged; Asthma; Autopsy; Basement Membrane; Bronchi; Child; Child, Preschool; Eosin	1971
Some histological changes in chronic bronchitis and asthma. Thorax, 1968, Volume: 23, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchitis; Bronchoscopy; Eosin	1968
Use of ultrasonic aerosols with ventilatory assistors. The Journal of asthma research, 1968, Volume: 5, Issue:4 Topics: Aerosols; Amphotericin B; Asthma; Bronchial Diseases; Bronchodilator Agents; Cystic Fibrosis; Eosino	1968
Allergic rhinitis or virus cold? Nasal smear eosinophilia in differential diagnosis. Annals of allergy, 1972, Volume: 30, Issue:4 Topics: Adolescent; Adult; Common Cold; Diagnosis, Differential; Eosinophilia; Female; Humans; Male; Mucus;	1972
Plastic bronchitis, mucoid impaction of the bronchi and allergic broncho-pulmonary aspergillosis, and their relationship to bronchial asthma. Annals of allergy, 1966, Volume: 24, Issue:11 Topics: Adolescent; Adult; Aged; Aspergillosis; Asthma; Bronchial Diseases; Bronchitis; Eosinophilia; Exudat	1966

guaifenesin and Eosinophilia, Tropical

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