guaifenesin has been researched along with Eosinophilia, Pulmonary in 41 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Excerpt | Relevance | Reference |
---|---|---|
"Chronic eosinophilic pneumonia is a rare cause of chronic lung disease in children." | 1.36 | Chronic eosinophilic pneumonia with mucous plugs in a child. ( Aksoy, F; Cakir, E; Cakır, FB; Ertem, T, 2010) |
" Inhalation of aerosolized p38alpha-ASO using an aerosol chamber dosing system produced measurable lung deposition of ASO and significant reduction of ovalbumin (OVA-)-induced increases in total cells, eosinophils, and interleukin 4 (IL-4), IL-5, and IL-13 levels in bronchoalveolar lavage fluid, and dose-dependent inhibition of airway hyperresponsiveness in allergen-challenged mice." | 1.33 | Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. ( Chan, JH; Choo, HH; Crosby, JR; Duan, W; Karras, JG; Leung, BP; McKay, K; Wong, WS, 2005) |
"This strategy resulted in a pulmonary eosinophilia equivalent to that observed in OVA-treated wild-type animals." | 1.32 | A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse. ( Ansay, TL; Biechelle, TL; Borchers, MT; Colbert, DC; Cormier, SA; Crosby, JR; Hines, EM; Justice, JP; Lee, JJ; Lee, NA; McGarry, MP; O'Neill, KR; Ochkur, SI; Shen, HH; Wang, H, 2003) |
"This is the first evidence that autoimmune diabetes-prone NOD mice can also give rise to enhanced Th2-mediated responses and might thus provide a useful model for the study of common genetic and cellular components, including NKT cells that contribute to both asthma and type 1 diabetes." | 1.32 | Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells. ( Araujo, LM; Bach, JF; Diem, S; Dy, M; Herbelin, A; Lefort, J; Leite-de-Moraes, MC; Nahori, MA; Vargaftig, BB; Zhu, R, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (7.32) | 18.7374 |
1990's | 2 (4.88) | 18.2507 |
2000's | 23 (56.10) | 29.6817 |
2010's | 8 (19.51) | 24.3611 |
2020's | 5 (12.20) | 2.80 |
Authors | Studies |
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Hearn, AP | 1 |
Mak, MS | 1 |
Budaj, I | 1 |
Qurashi, N | 1 |
Snell, O | 1 |
Dhariwal, J | 1 |
Nanzer, AM | 1 |
Jackson, DJ | 1 |
McIntosh, MJ | 2 |
Kooner, HK | 2 |
Eddy, RL | 2 |
Jeimy, S | 1 |
Licskai, C | 2 |
Mackenzie, CA | 2 |
Svenningsen, S | 1 |
Nair, P | 1 |
Yamashita, C | 2 |
Parraga, G | 2 |
Wilson, A | 1 |
Serajeddini, H | 1 |
Bhalla, A | 1 |
Sakai, N | 1 |
Koya, T | 1 |
Murai, Y | 1 |
Tsubokawa, F | 1 |
Tanaka, K | 1 |
Naramoto, S | 1 |
Aoki, A | 1 |
Shima, K | 1 |
Kimura, Y | 1 |
Watanabe, S | 1 |
Hasegawa, T | 1 |
Kikuchi, T | 1 |
Brown, R | 1 |
Paulsen, M | 1 |
Schmidt, S | 1 |
Schatterny, J | 1 |
Frank, A | 1 |
Hirtz, S | 1 |
Delaney, R | 1 |
Doherty, D | 1 |
Hagner, M | 1 |
Taggart, C | 1 |
Weldon, S | 1 |
Mall, MA | 1 |
Mochimaru, T | 1 |
Fukunaga, K | 1 |
Ueda, S | 1 |
Kuroda, A | 1 |
Watanabe, R | 1 |
Chubachi, S | 1 |
Betsuyaku, T | 1 |
Collison, A | 1 |
Li, J | 1 |
Pereira de Siqueira, A | 1 |
Zhang, J | 1 |
Toop, HD | 1 |
Morris, JC | 1 |
Foster, PS | 2 |
Mattes, J | 1 |
Nau, F | 1 |
Miller, J | 1 |
Saravia, J | 1 |
Ahlert, T | 1 |
Yu, B | 1 |
Happel, KI | 1 |
Cormier, SA | 2 |
Nichols, CD | 1 |
Sel, S | 1 |
Rost, BR | 1 |
Yildirim, AO | 1 |
Sel, B | 1 |
Kalwa, H | 1 |
Fehrenbach, H | 1 |
Renz, H | 1 |
Gudermann, T | 1 |
Dietrich, A | 1 |
Lee, NH | 1 |
Lee, MY | 2 |
Lee, JA | 1 |
Jung, DY | 1 |
Seo, CS | 1 |
Kim, JH | 2 |
Shin, HK | 1 |
Cakir, E | 1 |
Aksoy, F | 1 |
Cakır, FB | 1 |
Ertem, T | 1 |
Cho, JY | 2 |
Pham, A | 1 |
Rosenthal, P | 1 |
Miller, M | 2 |
Doherty, T | 1 |
Broide, DH | 2 |
Halim, TY | 1 |
Krauss, RH | 1 |
Sun, AC | 1 |
Takei, F | 1 |
Han, J | 1 |
Dakhama, A | 1 |
Jia, Y | 1 |
Wang, M | 1 |
Zeng, W | 1 |
Takeda, K | 1 |
Shiraishi, Y | 1 |
Okamoto, M | 1 |
Ziegler, SF | 1 |
Gelfand, EW | 2 |
Cohn, L | 2 |
Whittaker, L | 1 |
Niu, N | 1 |
Homer, RJ | 2 |
Shen, HH | 1 |
Ochkur, SI | 1 |
McGarry, MP | 1 |
Crosby, JR | 2 |
Hines, EM | 1 |
Borchers, MT | 1 |
Wang, H | 1 |
Biechelle, TL | 1 |
O'Neill, KR | 1 |
Ansay, TL | 1 |
Colbert, DC | 1 |
Justice, JP | 1 |
Lee, NA | 1 |
Lee, JJ | 1 |
ALBERICI, RA | 1 |
Araujo, LM | 1 |
Lefort, J | 2 |
Nahori, MA | 2 |
Diem, S | 1 |
Zhu, R | 1 |
Dy, M | 1 |
Leite-de-Moraes, MC | 1 |
Bach, JF | 1 |
Vargaftig, BB | 2 |
Herbelin, A | 1 |
Duan, W | 2 |
Chan, JH | 1 |
McKay, K | 1 |
Choo, HH | 1 |
Leung, BP | 2 |
Karras, JG | 1 |
Wong, WS | 2 |
Aguinaldo Datiles, AM | 1 |
Vlahos, CJ | 1 |
Xie, LX | 1 |
Mo, GX | 1 |
Chen, LA | 1 |
Liu, YN | 1 |
Oh, SR | 1 |
Ahn, K | 1 |
Park, BY | 1 |
Kwon, OK | 1 |
Joung, H | 1 |
Lee, J | 1 |
Kim, DY | 1 |
Lee, S | 1 |
Lee, HK | 1 |
Venkataraman, C | 1 |
Justen, K | 1 |
Zhao, J | 1 |
Galbreath, E | 1 |
Na, S | 1 |
Fulkerson, PC | 1 |
Fischetti, CA | 1 |
Rothenberg, ME | 2 |
Steenwinckel, V | 1 |
Louahed, J | 1 |
Orabona, C | 1 |
Huaux, F | 1 |
Warnier, G | 1 |
McKenzie, A | 1 |
Lison, D | 1 |
Levitt, R | 1 |
Renauld, JC | 1 |
Le, AV | 1 |
McElwain, S | 1 |
Golgotiu, K | 1 |
Han, X | 2 |
Fan, Y | 3 |
Wang, S | 3 |
Jiao, L | 1 |
Qiu, H | 1 |
Yang, X | 3 |
Henderson, WR | 2 |
Lewis, DB | 1 |
Albert, RK | 1 |
Zhang, Y | 1 |
Lamm, WJ | 1 |
Chiang, GK | 2 |
Jones, F | 2 |
Eriksen, P | 1 |
Tien, YT | 1 |
Jonas, M | 1 |
Chi, EY | 2 |
Zhu, L | 1 |
Wang, J | 1 |
Hong, L | 1 |
Lee, CG | 1 |
Jung, S | 1 |
Elias, JA | 1 |
Tomkinson, A | 1 |
Duez, C | 1 |
Cieslewicz, G | 1 |
Pratt, JC | 1 |
Joetham, A | 1 |
Shanafelt, MC | 1 |
Gundel, R | 1 |
Russo, M | 1 |
Gomes, E | 1 |
de Castro Keller, A | 1 |
Rodriguez, D | 1 |
Ribeiro, OG | 1 |
Adriouch, S | 1 |
Gallois, V | 1 |
de Faria, AM | 1 |
Pope, SM | 1 |
Brandt, EB | 1 |
Mishra, A | 1 |
Hogan, SP | 1 |
Zimmermann, N | 1 |
Matthaei, KI | 1 |
Walter, DM | 1 |
McIntire, JJ | 1 |
Berry, G | 1 |
McKenzie, AN | 1 |
Donaldson, DD | 1 |
DeKruyff, RH | 1 |
Umetsu, DT | 1 |
Oh, SW | 1 |
Pae, CI | 1 |
Lee, DK | 1 |
Kim, HO | 1 |
Moon, SH | 1 |
Cao, B | 1 |
Ogbu, C | 1 |
Jeong, KW | 1 |
Kozu, G | 1 |
Nakanishi, H | 1 |
Kahn, M | 1 |
Tigani, B | 1 |
Schaeublin, E | 1 |
Sugar, R | 1 |
Jackson, AD | 1 |
Fozard, JR | 1 |
Beckmann, N | 1 |
Yang, J | 1 |
Bilenki, L | 1 |
Chen, L | 1 |
Hurst, SD | 1 |
Muchamuel, T | 1 |
Gorman, DM | 1 |
Gilbert, JM | 1 |
Clifford, T | 1 |
Kwan, S | 1 |
Menon, S | 1 |
Seymour, B | 1 |
Jackson, C | 1 |
Kung, TT | 1 |
Brieland, JK | 1 |
Zurawski, SM | 1 |
Chapman, RW | 1 |
Zurawski, G | 1 |
Coffman, RL | 1 |
Mathew, A | 1 |
Medoff, BD | 1 |
Carafone, AD | 1 |
Luster, AD | 1 |
Geddes, DM | 1 |
Madewell, JE | 1 |
Montgomery, JL | 1 |
Cavanagh, RC | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Mechanistic Pilot Open-label Study to Evaluate the Effect of Benralizumab on Airway Function and Inflammation in Patients With Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI[NCT03733535] | 29 participants (Actual) | Interventional | 2022-03-01 | Active, not recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for guaifenesin and Eosinophilia, Pulmonary
Article | Year |
---|---|
Asthma Control, Airway Mucus, and
Topics: Airway Management; Airway Obstruction; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Ast | 2022 |
40 other studies available for guaifenesin and Eosinophilia, Pulmonary
Article | Year |
---|---|
The prevalence of mucus plugging in severe eosinophilic asthma and its relationship to clinical efficacy of anti-IL-5R treatment.
Topics: Asthma; Eosinophils; Humans; Mucus; Prevalence; Pulmonary Eosinophilia; Treatment Outcome | 2022 |
CT Mucus Score and
Topics: Airway Obstruction; Anti-Asthmatic Agents; Asthma; Humans; Magnetic Resonance Imaging; Mucus; Nitric | 2023 |
Effect of Benralizumab on Mucus Plugs in Severe Eosinophilic Asthma.
Topics: Anti-Asthmatic Agents; Asthma; Disease Progression; Eosinophils; Humans; Mucus; Pulmonary Eosinophil | 2023 |
Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.
Topics: Aging; Animals; Antibodies; Apoptosis; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Cytokine | 2020 |
Allergic bronchopulmonary aspergillosis in succession to chronic eosinophilic pneumonia.
Topics: Adult; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Bronchiectasis; Chronic Dise | 2019 |
Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease.
Topics: Airway Remodeling; Animals; Apoptosis; Blotting, Western; Bronchial Hyperreactivity; Cytokines; Immu | 2014 |
Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactiv | 2015 |
Loss of classical transient receptor potential 6 channel reduces allergic airway response.
Topics: Animals; Bronchial Hyperreactivity; Cells, Cultured; Epithelial Cells; Guinea Pigs; Hypersensitivity | 2008 |
Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokine | 2010 |
Chronic eosinophilic pneumonia with mucous plugs in a child.
Topics: Bronchoscopy; Child; Eosinophilia; Female; Humans; Mucus; Pulmonary Eosinophilia | 2010 |
Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchi; Collagen; Eosinophils; Extracellular Matrix | 2011 |
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation.
Topics: Adoptive Transfer; Allergens; Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression Pr | 2012 |
Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.
Topics: Animals; Animals, Newborn; Antibodies, Blocking; Bronchial Hyperreactivity; Cell Movement; Cells, Cu | 2012 |
Cytokine regulation of mucus production in a model of allergic asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Exocytos | 2002 |
A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse.
Topics: Adoptive Transfer; Aerosols; Allergens; Animals; Bronchial Hyperreactivity; CD4-Positive T-Lymphocyt | 2003 |
[Mucous plugs of bronchi in asthma & Hoffmann & Teichmüller eosinophilic catarrhs].
Topics: Asthma; Bronchi; Common Cold; Humans; Mucus; Pulmonary Eosinophilia; Respiratory Tract Diseases | 1957 |
Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD1; Antigens, CD1d; Asthma; Bronchial Hyperreactivity; B | 2004 |
Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.
Topics: Administration, Inhalation; Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar La | 2005 |
An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Chromones; C | 2005 |
Chronic eosinophilic pneumonia with mucous plugs: case report.
Topics: Adult; Chronic Disease; Female; Humans; Mucus; Pulmonary Eosinophilia | 2006 |
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disea | 2006 |
Death receptor-6 regulates the development of pulmonary eosinophilia and airway inflammation in a mouse model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Interferon-gamma; Mic | 2006 |
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.
Topics: Animals; Asthma; Chemokine CCL11; Chemokines, CC; Collagen; Eosinophils; Inflammation; Interleukin-1 | 2006 |
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells.
Topics: Animals; Asthma; Chemokine CCL11; Chemokines, CC; Epithelial Cells; Hematopoietic Stem Cell Transpla | 2007 |
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.
Topics: Activins; Allergens; Animals; Azo Compounds; Bronchial Hyperreactivity; Cell Movement; Collagen; Eos | 2007 |
NK cells contribute to intracellular bacterial infection-mediated inhibition of allergic responses.
Topics: Allergens; Animals; Cell Separation; Chlamydia muridarum; Cytokines; Female; Hypersensitivity; Kille | 2008 |
The importance of leukotrienes in airway inflammation in a mouse model of asthma.
Topics: 5-Lipoxygenase-Activating Proteins; Allergens; Animals; Asthma; Bronchial Provocation Tests; Broncho | 1996 |
Systemic mycobacterial infection inhibits antigen-specific immunoglobulin E production, bronchial mucus production and eosinophilic inflammation induced by allergen.
Topics: Allergens; Animals; Bronchi; Female; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Interferon-ga | 1999 |
IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Bronchoalveolar Lavage Fluid; Cytokines; G | 2000 |
A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness.
Topics: Animals; Antibody Specificity; B-Lymphocyte Subsets; Bronchial Hyperreactivity; Bronchoalveolar Lava | 2001 |
Suppression of asthma-like responses in different mouse strains by oral tolerance.
Topics: Administration, Inhalation; Administration, Oral; Animals; Antibodies; Antigens; Asthma; Bronchial P | 2001 |
IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism.
Topics: Animals; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Cytokines; Female; Interleukin-13; | 2001 |
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity.
Topics: Adoptive Transfer; Allergens; Animals; Immunity, Innate; Interferon-gamma; Interleukin-13; Interleuk | 2001 |
Tryptase inhibition blocks airway inflammation in a mouse asthma model.
Topics: Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Bronchial Diseases; Bronchial Hyperreactiv | 2002 |
Pulmonary inflammation monitored noninvasively by MRI in freely breathing rats.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Budesonide; Eosi | 2002 |
Mycobacterial infection inhibits established allergic inflammatory responses via alteration of cytokine production and vascular cell adhesion molecule-1 expression.
Topics: Animals; Antigens; Asthma; Cytokines; Endothelium, Vascular; Female; Immune Tolerance; Immunoglobuli | 2002 |
New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.
Topics: Adenoviridae; Administration, Intranasal; Amino Acid Motifs; Amino Acid Sequence; Animals; Aspergill | 2002 |
Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling.
Topics: Adoptive Transfer; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Cell Migration Inhibition; Cell | 2002 |
Pulmonary eosinophilia.
Topics: Aspergillosis, Allergic Bronchopulmonary; Asthma; Drug-Related Side Effects and Adverse Reactions; E | 1986 |
RPC from the AFIP.
Topics: Adenoma; Adult; Airway Obstruction; Arteriovenous Fistula; Bronchi; Bronchial Diseases; Carcinoma, B | 1973 |