guaifenesin has been researched along with Eosinophilia, Pulmonary in 41 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic eosinophilic pneumonia is a rare cause of chronic lung disease in children." | 1.36 | Chronic eosinophilic pneumonia with mucous plugs in a child. ( Aksoy, F; Cakir, E; Cakır, FB; Ertem, T, 2010) |
| " Inhalation of aerosolized p38alpha-ASO using an aerosol chamber dosing system produced measurable lung deposition of ASO and significant reduction of ovalbumin (OVA-)-induced increases in total cells, eosinophils, and interleukin 4 (IL-4), IL-5, and IL-13 levels in bronchoalveolar lavage fluid, and dose-dependent inhibition of airway hyperresponsiveness in allergen-challenged mice." | 1.33 | Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. ( Chan, JH; Choo, HH; Crosby, JR; Duan, W; Karras, JG; Leung, BP; McKay, K; Wong, WS, 2005) |
| "This strategy resulted in a pulmonary eosinophilia equivalent to that observed in OVA-treated wild-type animals." | 1.32 | A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse. ( Ansay, TL; Biechelle, TL; Borchers, MT; Colbert, DC; Cormier, SA; Crosby, JR; Hines, EM; Justice, JP; Lee, JJ; Lee, NA; McGarry, MP; O'Neill, KR; Ochkur, SI; Shen, HH; Wang, H, 2003) |
| "This is the first evidence that autoimmune diabetes-prone NOD mice can also give rise to enhanced Th2-mediated responses and might thus provide a useful model for the study of common genetic and cellular components, including NKT cells that contribute to both asthma and type 1 diabetes." | 1.32 | Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells. ( Araujo, LM; Bach, JF; Diem, S; Dy, M; Herbelin, A; Lefort, J; Leite-de-Moraes, MC; Nahori, MA; Vargaftig, BB; Zhu, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.32) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 23 (56.10) | 29.6817 |
| 2010's | 8 (19.51) | 24.3611 |
| 2020's | 5 (12.20) | 2.80 |
| Authors | Studies |
|---|---|
| Hearn, AP | 1 |
| Mak, MS | 1 |
| Budaj, I | 1 |
| Qurashi, N | 1 |
| Snell, O | 1 |
| Dhariwal, J | 1 |
| Nanzer, AM | 1 |
| Jackson, DJ | 1 |
| McIntosh, MJ | 2 |
| Kooner, HK | 2 |
| Eddy, RL | 2 |
| Jeimy, S | 1 |
| Licskai, C | 2 |
| Mackenzie, CA | 2 |
| Svenningsen, S | 1 |
| Nair, P | 1 |
| Yamashita, C | 2 |
| Parraga, G | 2 |
| Wilson, A | 1 |
| Serajeddini, H | 1 |
| Bhalla, A | 1 |
| Sakai, N | 1 |
| Koya, T | 1 |
| Murai, Y | 1 |
| Tsubokawa, F | 1 |
| Tanaka, K | 1 |
| Naramoto, S | 1 |
| Aoki, A | 1 |
| Shima, K | 1 |
| Kimura, Y | 1 |
| Watanabe, S | 1 |
| Hasegawa, T | 1 |
| Kikuchi, T | 1 |
| Brown, R | 1 |
| Paulsen, M | 1 |
| Schmidt, S | 1 |
| Schatterny, J | 1 |
| Frank, A | 1 |
| Hirtz, S | 1 |
| Delaney, R | 1 |
| Doherty, D | 1 |
| Hagner, M | 1 |
| Taggart, C | 1 |
| Weldon, S | 1 |
| Mall, MA | 1 |
| Mochimaru, T | 1 |
| Fukunaga, K | 1 |
| Ueda, S | 1 |
| Kuroda, A | 1 |
| Watanabe, R | 1 |
| Chubachi, S | 1 |
| Betsuyaku, T | 1 |
| Collison, A | 1 |
| Li, J | 1 |
| Pereira de Siqueira, A | 1 |
| Zhang, J | 1 |
| Toop, HD | 1 |
| Morris, JC | 1 |
| Foster, PS | 2 |
| Mattes, J | 1 |
| Nau, F | 1 |
| Miller, J | 1 |
| Saravia, J | 1 |
| Ahlert, T | 1 |
| Yu, B | 1 |
| Happel, KI | 1 |
| Cormier, SA | 2 |
| Nichols, CD | 1 |
| Sel, S | 1 |
| Rost, BR | 1 |
| Yildirim, AO | 1 |
| Sel, B | 1 |
| Kalwa, H | 1 |
| Fehrenbach, H | 1 |
| Renz, H | 1 |
| Gudermann, T | 1 |
| Dietrich, A | 1 |
| Lee, NH | 1 |
| Lee, MY | 2 |
| Lee, JA | 1 |
| Jung, DY | 1 |
| Seo, CS | 1 |
| Kim, JH | 2 |
| Shin, HK | 1 |
| Cakir, E | 1 |
| Aksoy, F | 1 |
| Cakır, FB | 1 |
| Ertem, T | 1 |
| Cho, JY | 2 |
| Pham, A | 1 |
| Rosenthal, P | 1 |
| Miller, M | 2 |
| Doherty, T | 1 |
| Broide, DH | 2 |
| Halim, TY | 1 |
| Krauss, RH | 1 |
| Sun, AC | 1 |
| Takei, F | 1 |
| Han, J | 1 |
| Dakhama, A | 1 |
| Jia, Y | 1 |
| Wang, M | 1 |
| Zeng, W | 1 |
| Takeda, K | 1 |
| Shiraishi, Y | 1 |
| Okamoto, M | 1 |
| Ziegler, SF | 1 |
| Gelfand, EW | 2 |
| Cohn, L | 2 |
| Whittaker, L | 1 |
| Niu, N | 1 |
| Homer, RJ | 2 |
| Shen, HH | 1 |
| Ochkur, SI | 1 |
| McGarry, MP | 1 |
| Crosby, JR | 2 |
| Hines, EM | 1 |
| Borchers, MT | 1 |
| Wang, H | 1 |
| Biechelle, TL | 1 |
| O'Neill, KR | 1 |
| Ansay, TL | 1 |
| Colbert, DC | 1 |
| Justice, JP | 1 |
| Lee, NA | 1 |
| Lee, JJ | 1 |
| ALBERICI, RA | 1 |
| Araujo, LM | 1 |
| Lefort, J | 2 |
| Nahori, MA | 2 |
| Diem, S | 1 |
| Zhu, R | 1 |
| Dy, M | 1 |
| Leite-de-Moraes, MC | 1 |
| Bach, JF | 1 |
| Vargaftig, BB | 2 |
| Herbelin, A | 1 |
| Duan, W | 2 |
| Chan, JH | 1 |
| McKay, K | 1 |
| Choo, HH | 1 |
| Leung, BP | 2 |
| Karras, JG | 1 |
| Wong, WS | 2 |
| Aguinaldo Datiles, AM | 1 |
| Vlahos, CJ | 1 |
| Xie, LX | 1 |
| Mo, GX | 1 |
| Chen, LA | 1 |
| Liu, YN | 1 |
| Oh, SR | 1 |
| Ahn, K | 1 |
| Park, BY | 1 |
| Kwon, OK | 1 |
| Joung, H | 1 |
| Lee, J | 1 |
| Kim, DY | 1 |
| Lee, S | 1 |
| Lee, HK | 1 |
| Venkataraman, C | 1 |
| Justen, K | 1 |
| Zhao, J | 1 |
| Galbreath, E | 1 |
| Na, S | 1 |
| Fulkerson, PC | 1 |
| Fischetti, CA | 1 |
| Rothenberg, ME | 2 |
| Steenwinckel, V | 1 |
| Louahed, J | 1 |
| Orabona, C | 1 |
| Huaux, F | 1 |
| Warnier, G | 1 |
| McKenzie, A | 1 |
| Lison, D | 1 |
| Levitt, R | 1 |
| Renauld, JC | 1 |
| Le, AV | 1 |
| McElwain, S | 1 |
| Golgotiu, K | 1 |
| Han, X | 2 |
| Fan, Y | 3 |
| Wang, S | 3 |
| Jiao, L | 1 |
| Qiu, H | 1 |
| Yang, X | 3 |
| Henderson, WR | 2 |
| Lewis, DB | 1 |
| Albert, RK | 1 |
| Zhang, Y | 1 |
| Lamm, WJ | 1 |
| Chiang, GK | 2 |
| Jones, F | 2 |
| Eriksen, P | 1 |
| Tien, YT | 1 |
| Jonas, M | 1 |
| Chi, EY | 2 |
| Zhu, L | 1 |
| Wang, J | 1 |
| Hong, L | 1 |
| Lee, CG | 1 |
| Jung, S | 1 |
| Elias, JA | 1 |
| Tomkinson, A | 1 |
| Duez, C | 1 |
| Cieslewicz, G | 1 |
| Pratt, JC | 1 |
| Joetham, A | 1 |
| Shanafelt, MC | 1 |
| Gundel, R | 1 |
| Russo, M | 1 |
| Gomes, E | 1 |
| de Castro Keller, A | 1 |
| Rodriguez, D | 1 |
| Ribeiro, OG | 1 |
| Adriouch, S | 1 |
| Gallois, V | 1 |
| de Faria, AM | 1 |
| Pope, SM | 1 |
| Brandt, EB | 1 |
| Mishra, A | 1 |
| Hogan, SP | 1 |
| Zimmermann, N | 1 |
| Matthaei, KI | 1 |
| Walter, DM | 1 |
| McIntire, JJ | 1 |
| Berry, G | 1 |
| McKenzie, AN | 1 |
| Donaldson, DD | 1 |
| DeKruyff, RH | 1 |
| Umetsu, DT | 1 |
| Oh, SW | 1 |
| Pae, CI | 1 |
| Lee, DK | 1 |
| Kim, HO | 1 |
| Moon, SH | 1 |
| Cao, B | 1 |
| Ogbu, C | 1 |
| Jeong, KW | 1 |
| Kozu, G | 1 |
| Nakanishi, H | 1 |
| Kahn, M | 1 |
| Tigani, B | 1 |
| Schaeublin, E | 1 |
| Sugar, R | 1 |
| Jackson, AD | 1 |
| Fozard, JR | 1 |
| Beckmann, N | 1 |
| Yang, J | 1 |
| Bilenki, L | 1 |
| Chen, L | 1 |
| Hurst, SD | 1 |
| Muchamuel, T | 1 |
| Gorman, DM | 1 |
| Gilbert, JM | 1 |
| Clifford, T | 1 |
| Kwan, S | 1 |
| Menon, S | 1 |
| Seymour, B | 1 |
| Jackson, C | 1 |
| Kung, TT | 1 |
| Brieland, JK | 1 |
| Zurawski, SM | 1 |
| Chapman, RW | 1 |
| Zurawski, G | 1 |
| Coffman, RL | 1 |
| Mathew, A | 1 |
| Medoff, BD | 1 |
| Carafone, AD | 1 |
| Luster, AD | 1 |
| Geddes, DM | 1 |
| Madewell, JE | 1 |
| Montgomery, JL | 1 |
| Cavanagh, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Mechanistic Pilot Open-label Study to Evaluate the Effect of Benralizumab on Airway Function and Inflammation in Patients With Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI[NCT03733535] | 29 participants (Actual) | Interventional | 2022-03-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for guaifenesin and Eosinophilia, Pulmonary
| Article | Year |
|---|---|
Asthma Control, Airway Mucus, and
Topics: Airway Management; Airway Obstruction; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Ast | 2022 |
40 other studies available for guaifenesin and Eosinophilia, Pulmonary
| Article | Year |
|---|---|
The prevalence of mucus plugging in severe eosinophilic asthma and its relationship to clinical efficacy of anti-IL-5R treatment.
Topics: Asthma; Eosinophils; Humans; Mucus; Prevalence; Pulmonary Eosinophilia; Treatment Outcome | 2022 |
CT Mucus Score and
Topics: Airway Obstruction; Anti-Asthmatic Agents; Asthma; Humans; Magnetic Resonance Imaging; Mucus; Nitric | 2023 |
Effect of Benralizumab on Mucus Plugs in Severe Eosinophilic Asthma.
Topics: Anti-Asthmatic Agents; Asthma; Disease Progression; Eosinophils; Humans; Mucus; Pulmonary Eosinophil | 2023 |
Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.
Topics: Aging; Animals; Antibodies; Apoptosis; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Cytokine | 2020 |
Allergic bronchopulmonary aspergillosis in succession to chronic eosinophilic pneumonia.
Topics: Adult; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Bronchiectasis; Chronic Dise | 2019 |
Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease.
Topics: Airway Remodeling; Animals; Apoptosis; Blotting, Western; Bronchial Hyperreactivity; Cytokines; Immu | 2014 |
Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactiv | 2015 |
Loss of classical transient receptor potential 6 channel reduces allergic airway response.
Topics: Animals; Bronchial Hyperreactivity; Cells, Cultured; Epithelial Cells; Guinea Pigs; Hypersensitivity | 2008 |
Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokine | 2010 |
Chronic eosinophilic pneumonia with mucous plugs in a child.
Topics: Bronchoscopy; Child; Eosinophilia; Female; Humans; Mucus; Pulmonary Eosinophilia | 2010 |
Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchi; Collagen; Eosinophils; Extracellular Matrix | 2011 |
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation.
Topics: Adoptive Transfer; Allergens; Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression Pr | 2012 |
Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.
Topics: Animals; Animals, Newborn; Antibodies, Blocking; Bronchial Hyperreactivity; Cell Movement; Cells, Cu | 2012 |
Cytokine regulation of mucus production in a model of allergic asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Exocytos | 2002 |
A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse.
Topics: Adoptive Transfer; Aerosols; Allergens; Animals; Bronchial Hyperreactivity; CD4-Positive T-Lymphocyt | 2003 |
[Mucous plugs of bronchi in asthma & Hoffmann & Teichmüller eosinophilic catarrhs].
Topics: Asthma; Bronchi; Common Cold; Humans; Mucus; Pulmonary Eosinophilia; Respiratory Tract Diseases | 1957 |
Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD1; Antigens, CD1d; Asthma; Bronchial Hyperreactivity; B | 2004 |
Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.
Topics: Administration, Inhalation; Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar La | 2005 |
An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Chromones; C | 2005 |
Chronic eosinophilic pneumonia with mucous plugs: case report.
Topics: Adult; Chronic Disease; Female; Humans; Mucus; Pulmonary Eosinophilia | 2006 |
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disea | 2006 |
Death receptor-6 regulates the development of pulmonary eosinophilia and airway inflammation in a mouse model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Interferon-gamma; Mic | 2006 |
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.
Topics: Animals; Asthma; Chemokine CCL11; Chemokines, CC; Collagen; Eosinophils; Inflammation; Interleukin-1 | 2006 |
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells.
Topics: Animals; Asthma; Chemokine CCL11; Chemokines, CC; Epithelial Cells; Hematopoietic Stem Cell Transpla | 2007 |
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.
Topics: Activins; Allergens; Animals; Azo Compounds; Bronchial Hyperreactivity; Cell Movement; Collagen; Eos | 2007 |
NK cells contribute to intracellular bacterial infection-mediated inhibition of allergic responses.
Topics: Allergens; Animals; Cell Separation; Chlamydia muridarum; Cytokines; Female; Hypersensitivity; Kille | 2008 |
The importance of leukotrienes in airway inflammation in a mouse model of asthma.
Topics: 5-Lipoxygenase-Activating Proteins; Allergens; Animals; Asthma; Bronchial Provocation Tests; Broncho | 1996 |
Systemic mycobacterial infection inhibits antigen-specific immunoglobulin E production, bronchial mucus production and eosinophilic inflammation induced by allergen.
Topics: Allergens; Animals; Bronchi; Female; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Interferon-ga | 1999 |
IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Bronchoalveolar Lavage Fluid; Cytokines; G | 2000 |
A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness.
Topics: Animals; Antibody Specificity; B-Lymphocyte Subsets; Bronchial Hyperreactivity; Bronchoalveolar Lava | 2001 |
Suppression of asthma-like responses in different mouse strains by oral tolerance.
Topics: Administration, Inhalation; Administration, Oral; Animals; Antibodies; Antigens; Asthma; Bronchial P | 2001 |
IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism.
Topics: Animals; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Cytokines; Female; Interleukin-13; | 2001 |
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity.
Topics: Adoptive Transfer; Allergens; Animals; Immunity, Innate; Interferon-gamma; Interleukin-13; Interleuk | 2001 |
Tryptase inhibition blocks airway inflammation in a mouse asthma model.
Topics: Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Bronchial Diseases; Bronchial Hyperreactiv | 2002 |
Pulmonary inflammation monitored noninvasively by MRI in freely breathing rats.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Budesonide; Eosi | 2002 |
Mycobacterial infection inhibits established allergic inflammatory responses via alteration of cytokine production and vascular cell adhesion molecule-1 expression.
Topics: Animals; Antigens; Asthma; Cytokines; Endothelium, Vascular; Female; Immune Tolerance; Immunoglobuli | 2002 |
New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.
Topics: Adenoviridae; Administration, Intranasal; Amino Acid Motifs; Amino Acid Sequence; Animals; Aspergill | 2002 |
Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling.
Topics: Adoptive Transfer; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Cell Migration Inhibition; Cell | 2002 |
Pulmonary eosinophilia.
Topics: Aspergillosis, Allergic Bronchopulmonary; Asthma; Drug-Related Side Effects and Adverse Reactions; E | 1986 |
RPC from the AFIP.
Topics: Adenoma; Adult; Airway Obstruction; Arteriovenous Fistula; Bronchi; Bronchial Diseases; Carcinoma, B | 1973 |