Page last updated: 2024-10-28

guaifenesin and Edema

guaifenesin has been researched along with Edema in 34 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have investigated the short-term effect of capsaicin on edema formation and goblet-cell secretion in the trachea."7.72Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation. ( Guo, JJ; Huang, HT; Wang, DS, 2003)
"Pirenzepine has been widely used for the treatment of gastric and duodenal ulcer."5.27Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat. ( Bustos-Fernández, L; Celener, D; González, E; Hamamura, S; Kofoed, JA; Ledesma de Paolo, MI; Schiffrin, E, 1987)
" subterranea (EEVS) was investigated for its gastroprotective effects on aspirin plus pylorus ligation-induced gastric ulcerated rats using an in vivo assay."3.88Protective roles of Vigna subterranea (Bambara nut) in rats with aspirin-induced gastric mucosal injury. ( Balogun, ME; Besong, EE; Djobissie, FSA; Mbamalu, OS; Obimma, JN, 2018)
"Previous studies have investigated the short-term effect of capsaicin on edema formation and goblet-cell secretion in the trachea."3.72Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation. ( Guo, JJ; Huang, HT; Wang, DS, 2003)
"In the present study the antiinflammatory activity of fusidic acid was investigated in a model of formalin-induced edema formation in rats."3.71The effects of fusidic acid on the inflammatory response in rats. ( Batu, O; Erol, K; Kilic, FS; Usluer, G; Yildirim, E, 2002)
"Diarrhea was seen after 16 hr, accompanying severe peritonitis."1.29Intestinal injuries caused by experimental palytoxicosis in mice. ( Ito, E; Ohkusu, M; Yasumoto, T, 1996)
"The tracheo-bronchial mucus viscosity was also significantly reduced (bronchitic animals) as was the fucose and total protein content."1.282-(2,3-Dihydro-5-acetoxy-4,6,7-tribenzofuranyl)acetic acid (IRFI 016): a new antioxidant mucoactive drug. ( Giannetti, P; Paesano, A; Scuri, R, 1990)
"Pirenzepine has been widely used for the treatment of gastric and duodenal ulcer."1.27Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat. ( Bustos-Fernández, L; Celener, D; González, E; Hamamura, S; Kofoed, JA; Ledesma de Paolo, MI; Schiffrin, E, 1987)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199017 (50.00)18.7374
1990's6 (17.65)18.2507
2000's4 (11.76)29.6817
2010's5 (14.71)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Coelho Thomazi, GO1
da Costa, A1
Rodrigues, JP1
Alves, GJ1
Prezotto Neto, JP1
de Oliveira Turíbio, T1
Rocha, AM1
da Silva Aires, R1
Seibert, CS2
Spencer, PJ1
Galisteo Júnior, AJ1
de Andrade Júnior, HF1
do Nascimento, N1
Oliveira, RG1
Damazo, AS1
Antonielli, LF1
Miyajima, F1
Pavan, E1
Duckworth, CA1
Lima, JCDS1
Arunachalam, K1
Martins, DTO1
Sáenz, A1
Ortiz, N1
Lomonte, B1
Rucavado, A1
Díaz, C1
Balogun, ME1
Besong, EE1
Obimma, JN1
Mbamalu, OS1
Djobissie, FSA1
Eller, R1
Ginsburg, M1
Lurie, D1
Heman-Ackah, Y1
Lyons, K1
Sataloff, R1
Hamdan, AL1
Sibai, A1
Mahfoud, L1
Oubari, D1
Ashkar, J1
Fuleihan, N1
Monteiro-dos-Santos, J1
Conceição, K1
Marques, EE1
Silva, PI1
Soares, AB1
Lima, C1
Lopes-Ferreira, M1
Postiaux, G1
Zwaenepoel, B1
Louis, J1
Guo, JJ1
Wang, DS1
Huang, HT1
CAPORAL, R1
Hogg, JC2
Bookman, R1
Ito, E1
Ohkusu, M1
Yasumoto, T1
Church, MK1
Levi-Schaffer, F1
Furuya, S1
Naruse, S1
Hayakawa, T1
Fahy, JV1
Corry, DB1
Boushey, HA1
Kilic, FS1
Erol, K1
Batu, O1
Yildirim, E1
Usluer, G1
Rainsford, KD1
Whitehouse, MW1
Tos, M1
Mogensen, C1
Woodson, BT1
Garancis, JC1
Toohill, RJ1
Piacentini, GL1
Kaliner, MA1
Scuri, R1
Giannetti, P1
Paesano, A1
Kaliner, M2
Bustos-Fernández, L1
González, E1
Kofoed, JA1
Hamamura, S1
Schiffrin, E1
Celener, D1
Ledesma de Paolo, MI1
Boquoi, E1
Kreuzer, G1
Krempien, B1
Wanke, M1
Ritz, E1
Shalygina, NB1
Dahlgren, SE1
Dalen, H1
Dalhamm, T1
Waldhalm, DG1
Hall, RF1
Meinershagen, WA1
Card, CS1
Frank, FW1
Swales, JD1
Tange, JD1
Evans, DJ1
Anderson, AE1
Foraker, AG1
Willems, G1
Gerard, A1
Verbeustel, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Randomized Controlled Trial: Evaluation of the Effects of Respiratory Physiotherapy, Placebo-controlled, in Infants With Moderate Acute Bronchiolitis[NCT03753802]168 participants (Anticipated)Interventional2019-12-01Recruiting
Measurement of Pharyngeal Sensitivity With the SENSITEST Device: Validation of the Diagnosis Algorithm for Sleep Disordered Breathing[NCT00885573]52 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for guaifenesin and Edema

ArticleYear
Chest physical therapy in acute viral bronchiolitis: an updated review.
    Respiratory care, 2013, Volume: 58, Issue:9

    Topics: Airway Obstruction; Algorithms; Bronchiolitis, Viral; Edema; Humans; Infant; Mucus; Nebulizers and V

2013
The pathology of asthma.
    Clinics in chest medicine, 1984, Volume: 5, Issue:4

    Topics: Asthma; Bronchi; Bronchial Spasm; Edema; Humans; Mucous Membrane; Mucus; Muscle, Smooth

1984
The human mast cell.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:2

    Topics: Bronchoconstriction; Cell Communication; Cell Differentiation; Cell Division; Cytokines; Edema; Endo

1997
Airway inflammation and remodeling in asthma.
    Current opinion in pulmonary medicine, 2000, Volume: 6, Issue:1

    Topics: Airway Obstruction; Asthma; Basement Membrane; Bronchi; Bronchial Hyperreactivity; Bronchitis; Const

2000
The potential roles of leukotrienes in bronchial asthma.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 2

    Topics: Airway Obstruction; Asthma; Edema; Humans; Hypersensitivity, Immediate; Leukotriene Antagonists; Leu

1991
Mechanisms of glucocorticosteroid action in bronchial asthma.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:2 Pt 2

    Topics: Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Asthma; Basophils; Bronchial Spasm; Capillar

1985
Mast cell mediators and asthma.
    Chest, 1987, Volume: 91, Issue:6 Suppl

    Topics: Animals; Asthma; Autacoids; Bronchial Spasm; Cytoplasmic Granules; Edema; Humans; Immunoglobulin E;

1987

Other Studies

27 other studies available for guaifenesin and Edema

ArticleYear
Paratrygon aiereba irradiated anti-mucus serum reduce edematogenic activity induced in experimental model.
    Toxicon : official journal of the International Society on Toxinology, 2020, Apr-30, Volume: 178

    Topics: Animals; Bites and Stings; Brazil; Edema; Elasmobranchii; Enzyme-Linked Immunosorbent Assay; Fresh W

2020
Dilodendron bipinnatum Radlk. extract alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration, TNF-α and IL-1β concentrations, IL-17 and COX-2 expressions, supporting mucus production and promotes an antioxidant ef
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Animals; Antioxidants; Brazil; Caco-2 Cells; Cell Survival; Colitis, Ulcerative; Cyclooxygenase 2; D

2021
Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles).
    Toxicon : official journal of the International Society on Toxinology, 2017, Volume: 137

    Topics: Age Factors; Animal Fins; Animals; Bone and Bones; Cattle; Cell Line; Cytotoxins; Edema; Fish Venoms

2017
Protective roles of Vigna subterranea (Bambara nut) in rats with aspirin-induced gastric mucosal injury.
    Journal of integrative medicine, 2018, Volume: 16, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Edema; Gastric Mucosa; Gastrointestinal Agents; G

2018
Flexible laryngoscopy: a comparison of fiber optic and distal chip technologies-part 2: laryngopharyngeal reflux.
    Journal of voice : official journal of the Voice Foundation, 2009, Volume: 23, Issue:3

    Topics: Edema; Erythema; Fiber Optic Technology; Humans; Laryngeal Diseases; Laryngoscopes; Laryngoscopy; Mu

2009
Short term effect of hubble-bubble smoking on voice.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:5

    Topics: Adolescent; Adult; Edema; Equipment Design; Erythema; Female; Health Knowledge, Attitudes, Practice;

2011
Studies on pharmacological properties of mucus and sting venom of Potamotrygon cf. henlei.
    International immunopharmacology, 2011, Volume: 11, Issue:9

    Topics: Animals; Anti-Infective Agents; Bacteria; Brazil; Edema; Elasmobranchii; Female; Fish Venoms; Fishes

2011
Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation.
    Anatomy and embryology, 2003, Volume: 206, Issue:4

    Topics: Acute Disease; Animals; Capsaicin; Cytoplasmic Granules; Disease Models, Animal; Edema; Goblet Cells

2003
[Value of the treatment of surgical edema by a new diffusion factor: 84-04-C].
    Gazette medicale de France, 1960, Jul-10, Volume: 67

    Topics: Diffusion; Edema; Mucus

1960
The pathophysiology of asthma.
    Chest, 1982, Volume: 82, Issue:1 Suppl

    Topics: Animals; Asthma; Bronchial Spasm; Bronchitis; Edema; Guinea Pigs; Humans; Lung; Mast Cells; Mucous M

1982
Ruminations on an atavism.
    Annals of allergy, 1980, Volume: 44, Issue:4

    Topics: Bronchial Spasm; Edema; Humans; Hypersensitivity; Mucus; Respiratory Hypersensitivity

1980
Intestinal injuries caused by experimental palytoxicosis in mice.
    Toxicon : official journal of the International Society on Toxinology, 1996, Volume: 34, Issue:6

    Topics: Acrylamides; Animals; Cnidarian Venoms; Diarrhea; Edema; Epithelium; Injections, Intraperitoneal; In

1996
Intravenous injection of guanylin induces mucus secretion from goblet cells in rat duodenal crypts.
    Anatomy and embryology, 1998, Volume: 197, Issue:5

    Topics: Animals; Atropine; Cell Count; Duodenum; Edema; Gastrointestinal Hormones; Hexamethonium; Humans; In

1998
The effects of fusidic acid on the inflammatory response in rats.
    Pharmacological research, 2002, Volume: 45, Issue:4

    Topics: Animals; Blood Cell Count; Edema; Foot; Formaldehyde; Fusidic Acid; Gastric Mucosa; Inflammation; Ma

2002
Gastric mucus effusion elicited by oral copper compounds: potential anti-ulcer activity.
    Experientia, 1976, Sep-15, Volume: 32, Issue:9

    Topics: Administration, Oral; Animals; Aspirin; Copper; Edema; Female; Foot; Gastric Mucosa; Hindlimb; Hydro

1976
Pathogenesis of nasal polyps.
    Rhinology, 1977, Volume: 15, Issue:2

    Topics: Adult; Child; Edema; Epithelium; Exocrine Glands; Granulation Tissue; Humans; Mucus; Nasal Mucosa; N

1977
Histopathologic changes in snoring and obstructive sleep apnea syndrome.
    The Laryngoscope, 1991, Volume: 101, Issue:12 Pt 1

    Topics: Atrophy; Dilatation, Pathologic; Edema; Exocrine Glands; Fibrosis; Humans; Hypertrophy; Male; Metapl

1991
2-(2,3-Dihydro-5-acetoxy-4,6,7-tribenzofuranyl)acetic acid (IRFI 016): a new antioxidant mucoactive drug.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:12

    Topics: Abscess; Animals; Antioxidants; Benzofurans; Bronchi; Carbon Tetrachloride Poisoning; Carrageenan; C

1990
Pirenzepine as anti-inflammatory drug in a model of experimental colitis in rat.
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1987, Volume: 37, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Colonic Diseases; Edema; Male; Mucus; Pirenzepine; R

1987
[Histomorphological investigations of endometrial carcinoma during progestional treatment with chlormadione acetate (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1973, Volume: 33, Issue:9

    Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Chlormadinon

1973
[Histochemical studies of gastric mucosa synthesis of mucous materials in uremia].
    Acta histochemica, 1973, Volume: SUPPL 13

    Topics: Animals; Edema; Female; Gastric Mucosa; Histocytochemistry; Humans; Male; Mucus; Rats; Uremia

1973
[Functional morphology of the mucous membrane of the small intestine in patients with cholera (according to aspiration biopsy data)].
    Arkhiv patologii, 1974, Volume: 26, Issue:11

    Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Biopsy, Needle; Capillaries; Carrier State; Cholera

1974
Ultrastructural observations on chemically induced inflammation in guinea pig trachea.
    Virchows Archiv. B, Cell pathology, 1972, Volume: 11, Issue:3

    Topics: Aldehydes; Animals; Cilia; Edema; Epithelial Cells; Female; Freeze Drying; Guinea Pigs; Inclusion Bo

1972
Haemophilus somnus infection in the cow as a possible contributing factor to weak calf syndrome: isolation and animal inoculation studies.
    American journal of veterinary research, 1974, Volume: 35, Issue:11

    Topics: Animals; Animals, Newborn; Arthritis, Infectious; Breeding; Cattle; Cattle Diseases; Edema; Female;

1974
Intestinal ammonia in uraemia: the effect of a urease inhibitor, acetohydroxamic acid.
    Clinical science, 1972, Volume: 42, Issue:1

    Topics: Ammonia; Animals; Blood Proteins; Cecum; Colitis; Colon; Edema; Erythrocytes; Hydroxamic Acids; Infl

1972
Bronchorrhea or bronchitis?
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Bronchi; Bronchial Diseases; Bronchitis; Cilia; Diagnosis, Differential; Edema; Epithelium; Exocrine

1971
Histochemical and histo-autoradiographical changes in gastric mucosa of dogs submitted to chronic cortisone administration.
    Digestion, 1971, Volume: 4, Issue:2

    Topics: Animals; Autoradiography; Biopsy; Cortisone; Dogs; Edema; Female; Gastric Mucosa; Glycoproteins; His

1971