guaifenesin has been researched along with Disease Models, Animal in 398 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 31 (7.79) | 18.7374 |
1990's | 24 (6.03) | 18.2507 |
2000's | 92 (23.12) | 29.6817 |
2010's | 196 (49.25) | 24.3611 |
2020's | 55 (13.82) | 2.80 |
Authors | Studies |
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Fan, J; Kuang, Y; Li, B; Qiao, X; Ye, M | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Jing, J; Ma, Q; Tong, H | 1 |
Heo, JD; Kim, JC; Kim, WI; Ko, JW; Lee, SJ; Lim, JO; Moon, C; Pak, SW; Shin, IS | 1 |
Du, X; Li, W; Liu, C; Liu, H; Qin, X; Qu, X; Wang, L; Wu, M; Xiang, Y; Yang, M; Yang, Y; Yuan, L; Zhou, K | 1 |
Jain, A; Moninger, TO; Pezzulo, AA; Powers, LS; Stoltz, DA; Thurman, AL; Welsh, MJ; Xie, Y; Yu, W; Zarei, K | 1 |
Jiang, W; Li, F; Liu, C; Liu, H; Liu, L; Ma, X; Pan, L; Qin, X; Qu, X; Wu, D; Xiang, Y | 1 |
Cabrita, I; Centeio, R; Göpferich, A; Graf, M; Kunzelmann, K; Ousingsawat, J; Schreiber, R; Talbi, K; Zimmer, O | 1 |
Aniscenko, J; Bartlett, NW; Boucher, RC; Calderazzo, M; Clarke, TB; Cookson, WO; Cross, MT; Evans, CM; Finney, LJ; Footitt, J; Johnston, SL; Kesimer, M; Lieleg, O; Mallia, P; Marczynski, M; Moffatt, MF; Molyneaux, PL; Radicioni, G; Singanayagam, A; Trujillo-Torralbo, MB; Wedzicha, J; Zhu, J | 1 |
Cheng, Y; Dong, Y; Fang, J; Lu, S; Song, C; Xue, Z; Yang, H; Zhang, H; Zhang, X; Zhang, Z; Zhou, Y | 1 |
Henry, PJ; Landwehr, KR; Larcombe, AN; Mann, TS; Noble, PB; Shamsuddin, D; Wang, KCW | 1 |
Abduwaki, M; Cui, J; Dong, JC; Luo, Q; Lv, Y; Nabijan, M; Nurahmat, M; Qin, J; Tang, W; Teng, F; Wang, S; Wei, Y; Wuniqiemu, T; Zhou, Y; Zhu, X | 1 |
Chen, L; Han, D; Huang, S; Li, T; Liu, X; Pang, J; Wang, J; Wu, Z; Zhang, B; Zhang, X; Zhao, J | 1 |
Boothby, MR; Chen, KW; Cho, SH; Eddie, AM; Gibson-Corley, KN; Keilhack, H; Kunii, K; Molina, JR; Niepel, M; Peebles, RS; Raybuck, AL; Schenkel, LB; Swinger, KK | 1 |
An, Y; Chen, J; Jiang, S; Li, Y; Liu, Y; Xu, Z; Zhang, H; Zhi, W | 1 |
Fu, L; Gao, L; Lu, X; Tan, ZX; Wang, H; Wang, WJ; Wang, Y; Xu, DX; Zhan, P; Zhao, H | 1 |
Ganama, M; Hua, X; Tilley, S; Varga, SM; Waldstein, KA | 1 |
Huang, J; Liu, Z; Ma, J; Tang, X; Wang, F; Wang, Y; Yang, X; Zhang, J | 1 |
Fang, YX; Hu, YM; Jiang, CH; Liu, YQ; Wang, JH; Yang, YY; Zhang, DJ; Zhang, J | 1 |
Cai, X; Cao, Y; Wang, C; Wang, Q; Xiao, J; Xu, K | 1 |
Beznoussenko, G; Briata, P; Bucci, G; Caputo, L; Chiacchiera, F; Ferracci, E; Garuti, A; Gherzi, R; Grillo, F; Hamadou, MH; Inga, A; Marcaccini, E; Mastracci, L; Mironov, A; Puri, PL; Silvestri, A; Zapparoli, E | 1 |
Babic Perhoc, A; De Busscher, J; Homolak, J; Joja, M; Knezovic, A; Osmanovic Barilar, J; Salkovic-Petrisic, M; Virag, D; Zambrano-Lucio, M | 1 |
Da, H; Fan, X; He, J; Hou, Y; Li, H; Liu, J; Liu, Y; Sun, X; Wang, D; Zhao, H; Zheng, S; Zhou, Y; Zou, F | 1 |
Hu, J; Liu, CY; Liu, L; Shi, XL; Sun, XH; Tang, LL; Wang, BH; Wang, Y; Yang, Y; Yu, KY; Zhang, Q; Zhang, XN | 1 |
Kim, T; Kim, WI; Lee, IS; Lee, SJ; Pak, SW; Shin, IS; Yang, YG | 1 |
Benedetto, R; Cabrita, I; Kunzelmann, K; Schreiber, R | 1 |
Ding, M; Fu, X; Guo, M; Liu, D; Pang, Y; Ren, Y; Wang, Z; Wei, L; Yao, N | 1 |
Aviello, G; Bourke, B; Conroy, E; D'Agostino, G; Gallagher, W; Knaus, UG; O'Neill, S; Scholz, D; Singh, AK; Walker, AW | 1 |
Gao, X; Ma, Y; Qian, J; Qian, Q; Shi, L; Yang, J; Zhang, Z; Zhu, X | 1 |
Delpire, E; Kabeer, MH; Koumangoye, R; Omer, S | 1 |
Finotto, S; Graser, A; Kiefer, A; Knipfer, L; Koch, S; Kölle, J; Melichar, VO; Mirzakhani, H; Papadopoulos, NG; Raby, BA; Rascher, W; Rieker, RJ; Weiss, ST; Wirtz, S; Zimmermann, T | 1 |
De Sanctis, JB; Dumut, DC; Garić, D; Hajduch, M; Hanrahan, JW; Kopriva, F; Peña, MJ; Petrof, BJ; Radzioch, D; Shah, J; Youssef, M | 1 |
Balázs, A; Mall, MA | 1 |
Jiang, H; Liu, W; Mao, B; Zhang, X | 1 |
Chen, L; Dong, J; Li, Y; Shen, Y; Wan, C; Wang, H; Wen, F; Wu, Y; Yang, T; Zeng, Z | 1 |
Gao, C; Li, F; Li, L; Liu, Y; Tong, X; Wang, T; Wu, D; Xu, J; Xue, X | 1 |
Jiang, X; Li, L; Liu, H; Liu, J; Liu, K; Yang, C; Zhang, X | 1 |
Hüttmann, G; König, P; Mall, MA; Pieper, M; Schulz-Hildebrandt, H | 1 |
Gregory Forest, M; Lai, SK; Miao, E; Newby, J; Schaefer, A; Schroeder, HA; Subramani, B; Tubbs, A | 1 |
Atanasova, KR; Bravo, L; Collins, EN; Dadural, JS; Eken, E; Guevara, MV; Kuan, SP; Liao, YSJ; Reznikov, LR; Schurmann, V; Sponchiado, M; Vogt, K | 1 |
Cavalcante-Silva, LHA; Cavalcanti, RFP; de Jesus, TG; Gadelha, FAAF; Paiva Ferreira, LAM; Paiva Ferreira, LKD; Piuvezam, MR; Vieira, GC | 1 |
Fu, Z; Hu, J; Ruan, L; Tian, D; Xue, K; Zou, W | 1 |
Deng, C; Dong, W; Duan, Y; Guo, Z; Han, Z; Sun, N; Wang, H; Zhang, R; Zhao, Q; Zhuang, G | 1 |
An, W; Shang, C; Su, Y; Wang, S; Yan, P; Yang, Y; Yu, C; Zhou, X | 1 |
Gil, CH; Jeon, YJ; Jo, A; Kim, HJ; Won, J | 1 |
Choi, W; Kuo, SH; Lau, GW; Maddox, CW; Mudalagiriyappa, S; Nanjappa, SG; Sieve, A; Vieson, M; Yang, AX | 1 |
Almeida, POA; Arunachalam, K; Cruz, TCDD; Damazo, AS; Figueiredo, FF; Martins, DTO; Oliveira, DM; Pavan, E; Silva, JVD; Venturini, CL | 1 |
Liu, L; Shen, Y; Wang, T; Wen, F; Xu, D; Yang, D; Yuan, Z | 1 |
Cui, J; Dong, J; Dong, M; Qin, J; Tang, W; Teng, F; Wang, S; Wang, W; Wei, Y; Wuniqiemu, T; Zhu, X | 1 |
Antonielli, LF; Arunachalam, K; Damazo, AS; Duckworth, CA; Lima, JCDS; Martins, DTO; Miyajima, F; Oliveira, RG; Pavan, E | 1 |
Duncan, G; El-Batal, HM; Emezienna, NA; Evans, CM; Grove Villalon, DE; Hanes, JS; Hara, N; Harder, AQ; Hennessy, CE; Holguin, F; Janssen, WJ; Jaramillo, AM; Magin, CM; Morgan, LE; NeeDell, JC; Raclawska, D; Richardson, VL; Shenoy, SK; Suk, JS; Thelin, WR; Thornton, DJ | 1 |
Cai, S; Huang, W; Liang, S; Liu, A; Wu, H; Yu, C; Zhou, Z | 1 |
Gan, SH; Hussain, FA; Johnathan, M; Mohd Fuad, WE; Muhamad, SA; Nurul, AA; Stanslas, J; Wan Ahmad, WAN | 1 |
Booth, R; Brown, R; Doherty, DF; Elborn, JS; Holsinger, L; Ingram, RJ; Mall, MA; Small, DM; Taggart, CC; Weldon, S; Williams, R | 1 |
Dewan, K; Easwaran, M; Erickson-DiRenzo, E; Martinez, JD; Sung, CK | 1 |
Fang, L; He, Z; Jiang, X; Wu, F; Xu, Z; Yan, Y; Yu, D; Yuan, X; Zhang, T; Zhou, S | 1 |
Ai, X; Chen, Q; Fang, Y; Gao, X; Hu, J; Huang, H; Jiang, D; Jiang, M; Li, Y; Qiang, L; Que, J; Ruan, J; Sung, HK; Wei, Z; Whitsett, JA | 1 |
Nong, G; Sun, H; Wei, Q; Xie, J; Zhang, X | 1 |
Li, C; Nian, Y; Yu, L; Zhao, D | 1 |
Chen, H; Chen, Z; Jing, D; Lai, T; Li, W; Li, Z; Shen, H; Shen, J; Wu, M; Wu, X; Wu, Y; Yang, S; Ying, S; Zhao, Y; Zhou, L | 1 |
Abdel-Motal, UM; Agrebi, N; Al-Marri, AA; Al-Shaibi, AA; Al-Subaiey, AA; Bullock, AN; Charles, AK; Elawad, M; Hubrack, SZ; Ibrahim, NA; Lo, B; Uhlig, HH | 1 |
Choudhary, I; Mao, Y; Patial, S; Paudel, K; Saini, Y; Vo, T; Yadav, R | 1 |
Cloots, E; De Wolf, C; Debeuf, N; Deswarte, K; Eyckerman, S; Fayazpour, F; Hammad, H; Janssens, S; Lambrecht, BN; Van De Velde, E; Vanheerswynghels, M | 1 |
Fujieda, S; Imoto, Y; Ishizuka, T; Kato, Y; Narita, N; Sakashita, M; Takabayashi, T; Tokunaga, T; Yoshida, K | 1 |
Akdis, CA; Akdis, M; Altunbulakli, C; Castro-Giner, F; Kubo, T; Martinez-Gonzalez, I; Matsumoto, K; Morita, H; Nakae, S; O'Mahony, L; Rückert, B; Steer, CA; Sudo, K; Sugita, K; Takei, F; Wawrzyniak, P | 1 |
Fang, S; Huang, S; Wang, C; Xu, B; Zhang, H; Zhang, Y | 1 |
Deshpande, DA; Knight, MJ; Nayak, AP; Oliver, B; Pan, S; Sharma, P; Tang, F; Wang, N; Yi, R | 1 |
Agapov, E; Bacharier, LB; Brown, S; Castro, M; Ehlers, A; Haspel, JA; Holtzman, MJ; Sajol, G; Schutz, R; Steinberg, D; Tidwell, R; Wang, X; Weaver, R; Xie, W; Yu, H | 1 |
Huang, R; Liu, C; Yang, A; Yao, R | 1 |
Brass, A; Cruickshank, SM; Else, KJ; Glymenaki, M; McBain, AJ; Singh, G; Warhurst, G | 1 |
Kwon, HJ; Moon, OS; Park, HS; Seo, CS; Son, HY; Song, JW; Wijerathne, CUB; Won, YS | 1 |
Langohr, I; Lewis, BW; Noël, A; Patial, S; Penn, AL; Saini, Y; Sharma, R; Sultana, R | 1 |
Bioley, G; Corthésy, B | 1 |
Fu, AK; Fu, LQ; Hu, SL; Li, WF; Li, YL; Wang, YY; Wu, YP | 1 |
Geng, W; Jiang, C; Li, C; Liu, Y; Liu, Z; Qin, S; Si, Y; Zhang, X; Zhang, Y; Zhao, S | 1 |
Cammer, M; Hamaguchi, S; Weiser, JN; Zafar, MA; Zangari, T | 1 |
Guan, R; Li, D; Liang, X; Long, Z; Lu, W; Wang, J; Wang, Z; Xie, J; Xu, J; Yang, Q; Zhao, L | 1 |
Beltrán, CJ; Bonilla, P; Bustamante, R; Iturra, PA; Méndez, A; Pérez, FJ; Ponce, CA; Rodríguez, H; Rojas, DA; Vargas, SL | 1 |
Chen, L; Hao, N; Shen, Y; Wang, H; Wang, T; Wen, F; Wu, Y; Yang, T; Yuan, Z | 1 |
Birket, SE; Chu, KK; Davis, JM; Fanucchi, MV; Fernandez, CM; Oden, AM; Rowe, SM; Sorscher, EJ; Tearney, GJ; Tuggle, KL | 1 |
Chen, HP; Chen, ZH; Li, W; Li, ZY; Shen, HH; Wang, Y; Xu, XC; Ying, SM; Zhou, JS | 1 |
Bao, A; Bao, W; Fei, X; Zhang, M; Zhang, X; Zhang, Y; Zhou, X | 1 |
Chen, T; Huang, Y; Jiang, H; Li, X; Lin, J; Lin, Z; Qu, H; Ren, P; Shang, M; Shi, M; Sun, H; Tang, Z; Xu, J; Yu, X; Zhao, L; Zhou, L; Zhou, X | 1 |
Dai, J; Ding, F; Fu, Z; Li, Q; Liu, B; Luo, Z; Tian, D; Zou, W | 1 |
Kryshen, K; Lehner, MD; Pongrácz, JE; Seibel, J | 1 |
Bähr, A; Dolan, B; Ermund, A; Hansson, GC; Klymiuk, N; Meiss, LN | 1 |
Cheng, L; Yang, J; Zhao, J; Zhao, R; Zhu, L | 1 |
Huang, T; Lin, P; Pu, Q; Qin, S; Singh, BB; Sun, Y; Wu, M; Zhao, Y; Zhou, C | 1 |
Bai, D; Crosby, J; Guo, S; Lv, T; Monia, BP; Zhao, C | 1 |
Akthar, S; Blalock, JE; Gaggar, A; Grabiec, AM; Gregory, LG; Hussell, T; Jackson, PL; Li, J; Lloyd, CM; Niven, RM; Patel, DF; Peiró, T; Shoemark, A; Simpson, A; Snelgrove, RJ; Steele, C; Tavernier, G; Trevor, JL; Walker, SA; Xu, X | 1 |
Arike, L; Åstrand, A; Ermund, A; Evans, CM; Fakih, D; Fernández-Blanco, JA; Hansson, GC; Jackson, S; Martínez-Abad, B; McCrae, C; Rodríguez-Piñeiro, AM; Root, J; Singh, D; Skansebo, E | 1 |
Boucher, RC; Delion, MF; Donaldson, SH; Ehre, C; Esther, CR; Fontana, NC; Grubb, BR; Hill, DB; Hothem, LN; Kato, T; Livraghi-Butrico, A; Markovetz, MR; Morrison, CB; Rushton, ZL; Thelin, WR; Villalon, D; Wang, B | 1 |
Choe, S; Choi, W; Fredrickson, RL; Lau, GW; Lin, J; Maddox, CW; Radwan, A; Steiner, M; Stern, AW; Waltenburg, MA; Yang, AX | 1 |
Biasin, V; Gungl, A; Kwapiszewska, G; Marsh, LM; Olschewski, A; Wilhelm, J | 1 |
Basic, M; Blaut, M; Bleich, A; Dahlke, K; Klopfleisch, R; Ring, C | 1 |
Jose, MMF; Rosa, MPG | 1 |
Ahmed, I; Anant, S; Owens, SM; Raach, RT; Roy, BC; Sampath, V; Umar, S; Xia, L | 1 |
Abou Alaiwa, MH; Fischer, AJ; Lu, L; Ostedgaard, L; Stoltz, DA; Xie, Y | 1 |
Ai, X; Aven, L; Barrios, J; Kho, AT; Miller, LA; Mitchel, JA; Park, JA; Randell, SH; Tantisira, KG | 1 |
Kim, JC; Kim, JS; Kim, SH; Ko, JW; Kwon, HJ; Lee, IC; Shin, IS; Shin, NR | 1 |
Abladey, A; Booth, R; Borensztajn, KS; Brown, RR; Delaney, RJ; Doherty, DF; Dougan, CM; Elborn, JS; Holsinger, L; Kerrigan, L; López-Campos, G; Mall, MA; Scott, CJ; Small, DM; Taggart, CC; Weldon, S; Zhou-Suckow, Z | 1 |
Amaro, R; Blasi, F; Carbonara, M; Chiurazzi, C; Comaru, T; De Rosa, F; Fernandez, L; Fraser, J; Frigola, G; Fuster, C; Li Bassi, G; Luque, N; Martí, D; Ramirez, J; Ranzani, OT; Rigol, M; Saco, MA; Suen, J; Torres, A; Travierso, C; Xiol, EA; Zanella, A | 1 |
Bromfield, JJ; Dickson, MJ; Jeong, KC; Ma, Z; Molinari, PCC; Piersanti, RL; Santos, JEP; Sheldon, IM; Zimpel, R | 1 |
Ahn, KS; Choi, S; Kwon, OK; Lee, JW; Min, JH; Oh, SR; Paik, JH; Park, HA; Park, MH; Park, MW; Paryanto, I; Ryu, HW; Yuniato, P | 1 |
Baker, SM; Birket, SE; Bowers, HL; Chu, KK; Clancy, JP; Engelhardt, JF; Evans, TIA; Fernandez-Petty, CM; Garcia, BA; Hanes, J; Hathorne, H; Hughes, GW; Leung, HM; Li, Y; Libby, EF; Mazur, M; Ridley, CE; Rosen, BH; Rowe, SM; Santos, C; Swords, WE; Tearney, GJ; Thornton, DJ; Townsend, SM; Watson, JD; Wiesmann, WP | 1 |
Reddehase, MJ | 1 |
Aegerter, H; Bachert, C; Blanchetot, C; Chanez, P; Dansercoer, A; De Haard, H; Deswarte, K; Gevaert, E; Gonçalves, A; Gras, D; Hammad, H; Heyndrickx, I; Lambrecht, BN; Percier, JM; Persson, EK; Saunders, M; Savvides, SN; Van Gorp, H; Verschueren, KHG; Verstraete, K | 1 |
Li, X; Zhang, W; Zhang, Y | 1 |
Ismagilov, RF; Preska Steinberg, A; Wang, ZG | 1 |
Cheng, Z; Liu, Y; Shi, J; Wang, H | 1 |
Cerqueira, JV; de Aragão França, LS; de Melo, TL; Dos Santos Filho, JM; Meira, CS; Moreira, DRM; Nonaka, CKV; Santos, ES; Soares, MBP; Vasconcelos, JF | 1 |
Boschetti, G; Castillo-Martin, M; Chen, E; Cho, JH; Chu, J; Chuang, LS; Facey, JA; Giri, M; Hsu, NY; Labrias, PR; Morrison, J; Nayar, S; Sharma, Y; Thin, TH; Villaverde, N | 1 |
Alves, F; Biffi, S; Bosnjak, B; Dal Monego, S; Dullin, C; Epstein, MM; Garrovo, C; Licha, K; Welker, P | 1 |
Aguilera-Aguirre, L; Boldogh, I; Boulares, HA; Calhoun, WJ; Naura, AS; Ramana, KV; Srivastava, SK; Yadav, UC | 1 |
Ha, H; Jeon, WY; Kim, JH; Lee, MY; Lim, HS; Shin, IS | 1 |
Boucher, RC; Graeber, SY; Hirtz, S; Mall, MA; Schatterny, J; Zhou-Suckow, Z | 1 |
Chu, X; Guan, M; Wang, D; Wei, M; Xie, X; Yang, X | 1 |
Abdelouhab, K; Djeraba, Z; Rafa, H; Raissi-Kerboua, D; Soufli, I; Touil-Boukoffa, C; Toumi, R | 1 |
Bouet, S; Bridonneau, C; Cherbuy, C; Joncquel Chevalier-Curt, M; Langella, P; Miquel, S; Noordine, ML; Philippe, C; Robbe-Masselot, C; Robert, V; Thomas, M; Wrzosek, L | 1 |
Griebel, P; Kusalik, A; Määttänen, P; Napper, S; Potter, A; Scruten, E; Trost, B | 1 |
Anderson, LJ; Barnum, TR; Boyoglu, C; Boyoglu-Barnum, S; Chirkova, T; Gaston, KA; Haynes, LM; Jorquera, P; Moore, ML; Todd, SO; Tripp, RA | 1 |
Collison, AM; Essilfie, AT; Foster, PS; Hansbro, PM; Hatchwell, LM; Horvat, JC; Kim, RY; Mattes, J; Nguyen, DH; Starkey, MR; Yagita, H | 1 |
Bosnjak, B; Dekan, G; Epstein, MM; Erb, KJ; Pieper, MP; Tilp, C; Tomsic, C | 1 |
Jeon, WY; Lee, MY; Shin, HK; Shin, IS | 1 |
de Beer, R; de Boer, JD; de Vos, AF; Hoogendijk, AJ; Roelofs, JJ; van 't Veer, C; van den Boogaard, FE; van der Poll, T; van der Zee, JS; Yang, J | 1 |
Cormier, SA; Lee, GI; Lomnicki, S; Saravia, J; Shrestha, B; Thevenot, P; You, D | 1 |
Hansson, GC; Johansson, ME | 1 |
Dekker, J; Jaklofsky, MT; Loonen, LM; Meijerink, M; Stolte, EH; van Baarlen, P; Wells, JM | 1 |
Ahl, D; Carding, SR; Holm, L; Juge, N; Kober, OI; Pin, C | 1 |
Gu, W; Mao, S; Shi, Y; Tan, Y | 1 |
Belaaouaj, A; Dalpke, AH; Duerr, J; Gehrig, S; Graeber, SY; Hirtz, S; Mall, MA; Schatterny, J; Schultz, C; Wagner, CJ; Weitnauer, M | 1 |
Levendoski, EE; Leydon, C; Thibeault, SL | 1 |
Bahlmann, O; Hohlfeld, JM; Hoymann, HG; Knudsen, L; Madsen, J; Ochs, M; Thum, T; Viereck, J; Wedekind, D; Winkler, C | 1 |
Poole, JA; Sanderson, SD; Staab, EB; Wells, SM | 1 |
Alli, V; Deitch, EA; Fishman, JE; Levy, G; Mole, DJ; Zheng, X | 1 |
Ahn, KS; Hong, JM; Jeon, CM; Kim, HS; Kwon, OK; Myung, PK; Oh, SR; Shin, IS; Shin, NR | 1 |
Gao, N; He, Q; Hou, W; Jiang, C; Lan, X; Liu, H; Liu, L; Lu, S; Sun, Q; Tian, J; Yang, X; Zhong, B | 1 |
Awadalla, MA; Fischer, AJ; Hoegger, MJ; Hoffman, EA; McMenimen, JD; Michalski, AS; Moninger, TO; Ostedgaard, LS; Stoltz, DA; Tucker, AJ; Welsh, MJ; Zabner, J | 1 |
Almeida, FM; Carvalho, CR; Martins, MA; Olivo, CR; Saraiva-Romanholo, BM; Silva, RA | 1 |
Ahn, KS; Jeon, CM; Kim, JC; Kim, JS; Kwon, OK; Oh, SR; Park, JW; Shin, IS; Shin, NR | 1 |
Ahn, KS; Hong, JM; Jeon, CM; Kim, JC; Kim, JS; Kwon, OK; Lee, IC; Oh, SR; Park, JW; Shin, IS; Shin, NR | 1 |
Maria, DA; Toledo-Piza, AR | 1 |
Ding, PS; Fang, L; He, F; Liu, RY; Shen, QY; Wu, HM | 1 |
Ahlert, T; Cormier, SA; Happel, KI; Miller, J; Nau, F; Nichols, CD; Saravia, J; Yu, B | 1 |
Akiko Hiruma-Lima, C; Aparecido Dos Santos Ramos, M; Bonamin, F; Campaner Dos Santos, L; Damacena de Angelis, C; José Mininel, F; Karina Delella, F; Kushima, H; Luis Felisbino, S; Maria Bauab, T; Pinheiro Silva, L; Regina Machado da Rocha, L; Toma, W; Vilegas, W | 1 |
Haworth, O; Karra, L; Levi-Schaffer, F; Levy, BD; Priluck, R | 1 |
Chen, M; Huang, L; Jiang, S; Liang, R; Lin, X; Lv, Z; Shi, J; Zhang, W | 1 |
Li, H; Li, W; Mu, Q; Niu, X; Wang, Y; Yao, H; Zhang, H | 1 |
de Kretser, DM; Hardy, CL; Hedger, MP; King, SJ; Mackay, F; Mifsud, NA; O'Hehir, RE; Phillips, DJ; Rolland, JM; Wilson, JW | 1 |
Busse, P; Emala, C; Li, XM; Liu, C; Weir, D; Yang, N; Zhou, Z | 1 |
Adami, AJ; Andemariam, B; Guernsey, LA; McNamara, JT; Secor, ER; Singh, A; Thrall, RS | 1 |
Alcântara-Neves, NM; Alves de Souza, S; da Silva Velozo, E; Ferreira Silva, HB; Figueiredo, CA; Meneses Souza, FL; Pires de Oliveira, A; Pontes-de-Carvalho, LC; Rios, R; Santos Alves, W; Santos Costa, R; Santos Serafim Machado, M; Sarmento Silva, TM; Silva, ML; Vilany Queiroz Carneiro, N | 1 |
Abuohashish, HM; Ahmed, MM; Al-Hosaini, KA; Al-Rejaie, SS; Fatani, AJ; Parmar, MY | 1 |
Chen, Z; Cormier, SA; Dugas, TR; Jaligama, S; Lomnicki, SM; Saravia, J; Yadav, N | 1 |
Akira, S; Sanjo, H; Taki, S; Tokumaru, S | 1 |
Fang, L; Liu, RY; Shen, QY; Wu, HM | 1 |
Al-Ghareeb, K; Al-Khami, AA; Boulares, AH; El-Bahrawy, AH; Ghonim, MA; Ibba, SV; Lammi, MR; Mansy, MS; Naura, AS; Ochoa, A; Pyakurel, K; Rady, HF; Ramsay, A; Rodriguez, P; Wang, J | 1 |
Li, G; Luo, G; Wang, X; Wu, M; Xie, T; Zhang, Y | 1 |
Aihua, B; Feng, L; Xin, Z; Yuqing, C; Zhang, M | 1 |
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Cohen, JC; Cork, RJ; Delcarpio, JB; Larson, JE; Morrow, SL | 1 |
Cole, PJ; Pritchard, K; Wills, PJ | 1 |
Fariñas Medina, M; Infante Bourzac, JF; López Hernández, Y; Marrero Chang, O; Muñoz Carnago, E; Sifontes Rodríguez, S | 1 |
Katoh, Y; Kawashima, H; Tanaka, M | 1 |
Bottomly, K; Cohn, L; Homer, RJ; Niu, N | 1 |
Chi, EY; Henderson, WR; Maliszewski, CR | 1 |
Chi, EY; Dietsch, GN; Henderson, WR; Lu, J; Poole, KM | 1 |
Bertrand, C; El-Hashim, A; Trifilieff, A | 1 |
Brasil, DD; Brito, AR; de Almeida, AB; de Paula, AC; Gracioso, JD; Hiruma-Lima, CA; Muller, AH; Toma, W | 1 |
Ashida, Y; Fujino, M; Fujisawa, Y; Iwashita, H; Morita, S; Nakanishi, A; Nishimura, O; Sagiya, Y; Shirafuji, H | 1 |
Hancock, RE; Iwama, GK; Mendoza, V; Patrzykat, A; Zhang, L | 1 |
Adriouch, S; de Castro Keller, A; de Faria, AM; Gallois, V; Gomes, E; Lefort, J; Nahori, MA; Ribeiro, OG; Rodriguez, D; Russo, M; Vargaftig, BB | 1 |
Hase, T; Meguro, S; Sakata, T; Shimotoyodome, A; Tokimitsu, I | 1 |
Mohammadu, F; Puddington, L; Schramm, CM; Thrall, RS; Whiteley, HE; Wu, CA; Yiamouyiannis, CA | 1 |
Boucher, RC; Davis, CW; Grubb, BR; Hirsh, AJ; Parsons, D; Picher, M; Tarran, R | 1 |
Hashimoto, K; Hirano, K; Ishii, Y; Kimura, T; Masuyama, K; Morishima, Y; Nomura, A; Sagai, M; Sakamoto, T; Sekizawa, K; Takano, H; Uchida, Y | 1 |
Fahy, JV | 1 |
Boucher, RC; Chadburn, JL; Grubb, BR | 1 |
Ishihara, Y; Kawashima, H; Kyono, H; Miyasaka, M; Serita, F; Toya, T | 1 |
Englert, E; Freston, JW; Harman, CG; Straight, RC; Wales, EE | 1 |
Jones, R | 1 |
Reid, L | 3 |
Widdicombe, JG | 1 |
Reid, LM | 1 |
Boucher, RC; Brigman, KK; Koller, BH; Latour, AM; Malouf, NN; Smithies, O; Snouwaert, JN | 1 |
Carlsöö, B; Kumlien, J; Stierna, P | 1 |
Barbeau, J; Deslauriers, N | 1 |
Burris, JA; O'Brien, AD; Wadolkowski, EA | 1 |
Hanada, S; Kawai, M; Kohno, S; Nagaya, Y; Nishimura, F; Okamoto, Y; Takeoka, A; Tanaka, K | 1 |
Haley-Russell, D; Husband, K; Myers, SI; Parks, L | 1 |
Maltarello, MC; Müller, RM; Roomans, GM; Versura, P | 1 |
Bhaskar, KR; Drazen, JM; O'Sullivan, DD; Reid, LM; Scanlon, PM | 1 |
Disse, BG; Ziegler, HW | 1 |
Vol'fson, NI | 1 |
Berendt, RF | 1 |
Zaidi, SH | 1 |
Kilburn, KH; Rylander, R | 1 |
Kilburn, KH | 1 |
Chakrin, LW; Saunders, LZ | 1 |
Dalhamn, T; Rylander, R | 1 |
Chakrin, LW; Payne, BJ; Wardell, JR | 1 |
Rylander, R | 1 |
Green, GM | 1 |
Barry, DH; Healey, P; Mawdesley-Thomas, LE | 1 |
23 review(s) available for guaifenesin and Disease Models, Animal
Article | Year |
---|---|
Mucus obstruction and inflammation in early cystic fibrosis lung disease: Emerging role of the IL-1 signaling pathway.
Topics: Airway Obstruction; Animals; Child; Child, Preschool; Cystic Fibrosis; Disease Models, Animal; Humans; Inflammation; Interleukin-1; Mice; Mucus; Signal Transduction | 2019 |
Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways.
Topics: Animals; Animals, Newborn; Cystic Fibrosis; Disease Models, Animal; Mucociliary Clearance; Mucus; Respiratory Mucosa; Swine | 2018 |
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease.
Topics: Animals; Asthma; Cell Differentiation; Cytokines; Cytomegalovirus Infections; Dendritic Cells; Disease Models, Animal; Goblet Cells; Mice; Mucus; Th2 Cells | 2019 |
Mucus and the goblet cell.
Topics: Animals; Colitis, Ulcerative; Disease Models, Animal; Goblet Cells; Humans; Mucins; Mucus | 2013 |
Vocal fold epithelial barrier in health and injury: a research review.
Topics: Air Pollutants; Animals; Aquaporins; Cell Membrane; Disease Models, Animal; Humans; Intercellular Junctions; Intraoperative Complications; Ion Transport; Irritants; Mucus; Rats; Respiratory Mucosa; Tobacco Smoke Pollution; Vibration; Vocal Cord Dysfunction; Vocal Cords | 2014 |
Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models.
Topics: Animals; Cilia; Disease Models, Animal; Mice; Mucociliary Clearance; Mucus; Respiratory Mechanics; Respiratory Tract Diseases | 2008 |
A view on imaging in drug research and development for respiratory diseases.
Topics: Animals; Clinical Trials as Topic; Diagnostic Imaging; Disease Models, Animal; Drug Delivery Systems; Drug Design; Humans; Hypertension, Pulmonary; Inflammation; Lung; Magnetic Resonance Imaging; Mucociliary Clearance; Mucus; Pharmacology, Clinical; Pulmonary Circulation; Pulmonary Fibrosis; Respiratory Mechanics; Respiratory Tract Diseases | 2011 |
CFTR, mucins, and mucus obstruction in cystic fibrosis.
Topics: Airway Obstruction; Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Gastrointestinal Tract; Gene Expression Regulation; Genitalia; Glycoproteins; Glycosylation; Humans; Lung; Male; Mice; Mucin 5AC; Mucins; Mucus; Pneumonia; RNA, Messenger | 2012 |
Regulation of mucin genes in chronic inflammatory airway diseases.
Topics: Animals; Asthma; Cystic Fibrosis; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Lipopolysaccharides; Lung; Mucin 5AC; Mucin-2; Mucins; Mucus; Pneumonia; Pulmonary Disease, Chronic Obstructive; Transcription, Genetic | 2006 |
The roles of mucus-associated bacteria in inflammatory bowel disease.
Topics: Adult; Animals; Disease Models, Animal; Helicobacter; Humans; Inflammatory Bowel Diseases; Mucus | 2006 |
Cystic fibrosis and other respiratory diseases of impaired mucus clearance.
Topics: Animals; Cilia; Cystic Fibrosis; Disease Models, Animal; Female; Gene Silencing; Humans; Male; Mice; Mice, Knockout; Mucociliary Clearance; Mucus; Respiratory System | 2007 |
Respiratory syncytial virus-induced pulmonary disease and exacerbation of allergic asthma.
Topics: Animals; Asthma; Chemokines; Dendritic Cells; Disease Models, Animal; Humans; Immunity, Innate; Mice; Mucus; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Toll-Like Receptors | 2007 |
Experimental models of asthma.
Topics: Airway Resistance; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Cilia; Disease Models, Animal; Dogs; Humans; Mucus; Sheep; Trachea | 1982 |
Experimental studies on the pathophysiology of peptic ulcer disease.
Topics: Animals; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Humans; Mucus; Peptic Ulcer; Stomach Ulcer | 1982 |
Clinical aspects of respiratory mucus.
Topics: Animals; Bronchi; Bronchitis; Calcium; Cilia; Colchicine; Cytochalasin B; Disease Models, Animal; Humans; Mucus; Organ Culture Techniques; Prostaglandins; Proteoglycans; Respiratory Physiological Phenomena; Sputum; Vasopressins | 1982 |
[Mechanisms of bronchial hyperreactivity. Role of the epithelium].
Topics: Animals; Antigens, CD; Asthma; Biopsy; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capillary Permeability; Case-Control Studies; Cell Adhesion Molecules; Dinoprostone; Disease Models, Animal; Endothelins; Epithelial Cells; Epithelium; HLA-DR Antigens; Humans; Hydroxyeicosatetraenoic Acids; Intercellular Adhesion Molecule-1; Mucus; Muscle, Smooth | 1994 |
Experimental models for studying mucociliary clearance.
Topics: Animals; Cough; Disease Models, Animal; Elasticity; Humans; Models, Biological; Mucociliary Clearance; Mucus; Rheology; Viscosity | 1998 |
Virulence Enhancement Agents for Haemophilus influenzae type B infection in mice.
Topics: Animals; Dextrans; Disease Models, Animal; Haemophilus Infections; Haemophilus influenzae type b; Hemoglobins; Iron; Male; Mice; Mice, Inbred BALB C; Mineral Oil; Mucus; Trypsin | 1999 |
Remodeling of the airway epithelium in asthma.
Topics: Animals; Asthma; Biopsy; Bronchi; Bronchoconstriction; Capillary Permeability; Cell Degranulation; Cell Size; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Goblet Cells; Guinea Pigs; Humans; Hyperplasia; Immunoassay; Mice; Mucins; Mucus; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2001 |
Secretory cells.
Topics: Animals; Bronchi; Disease Models, Animal; Epithelium; Glycoproteins; Humans; Mice; Mucus; Nicotiana; Organ Culture Techniques; Oxadiazoles; Plants, Toxic; Rats; Smoke | 1977 |
The cell biology of mucus secretion in the lung.
Topics: Animals; Disease Models, Animal; Epithelial Cells; Glycoproteins; Humans; Lung; Lung Diseases; Mucus; Organ Culture Techniques | 1978 |
[Morphological and molecular biological aspects of the origin of experimental stomach cancer].
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelium; Gastric Mucosa; Humans; Methylnitronitrosoguanidine; Mice; Mucus; Precancerous Conditions; Rats; Stomach; Stomach Neoplasms | 1985 |
Biological effects of cigarette smoking in the pathogenesis of pulmonary disease.
Topics: Animals; Bacteriolysis; Bronchi; Cell Movement; Cilia; Disease Models, Animal; Environmental Exposure; Humans; Hyperplasia; Leukocytes; Lung; Lung Diseases; Macrophages; Metaplasia; Mucus; Pulmonary Alveoli; Smoke; Smoking | 1973 |
375 other study(ies) available for guaifenesin and Disease Models, Animal
Article | Year |
---|---|
Antitussive and expectorant activities of licorice and its major compounds.
Topics: Administration, Oral; Ammonia; Animals; Antitussive Agents; Cough; Disease Models, Animal; Dose-Response Relationship, Drug; Expectorants; Glyburide; Glycyrrhiza; Male; Methysergide; Mice; Mice, Inbred ICR; Molecular Structure; Phenolsulfonphthalein; Plant Extracts; Structure-Activity Relationship | 2018 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
High throughput virtual screening strategy to develop a potential treatment for bronchial asthma by targeting interleukin 13 cytokine signaling.
Topics: Animals; Asthma; Child; Cytokines; Disease Models, Animal; Epinephrine; Guaifenesin; Humans; Hypersensitivity; Immunoglobulin E; Interleukin-13; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Ovalbumin; Th2 Cells | 2022 |
Titanium Dioxide Nanoparticles Exacerbate Allergic Airway Inflammation via TXNIP Upregulation in a Mouse Model of Asthma.
Topics: Animals; Apoptosis; Asthma; bcl-2-Associated X Protein; Bronchoalveolar Lavage Fluid; Carrier Proteins; Caspase 3; Cell Count; Cell Line; Chemical Phenomena; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Hypersensitivity; Immunoglobulin E; Inflammation; Inflammation Mediators; Lung; MAP Kinase Kinase Kinase 5; Mice; Mucus; Nanoparticles; Ovalbumin; Respiratory Hypersensitivity; RNA, Messenger; Thioredoxins; Titanium; Up-Regulation | 2021 |
ITGB4 deficiency induces mucus hypersecretion by upregulating MUC5AC in RSV-infected airway epithelial cells.
Topics: Animals; Disease Models, Animal; Epithelial Cells; Humans; Integrin beta4; Mice; Mucin 5AC; Mucus; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Up-Regulation | 2022 |
Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs.
Topics: Acinar Cells; Animals; Biomarkers; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Fluorescent Antibody Technique; Gene Expression; Gene Knockdown Techniques; Genetic Predisposition to Disease; Mucins; Mucociliary Clearance; Mucus; Mutation; Respiratory Mucosa; Swine | 2022 |
CTNNAL1 participates in the regulation of mucus overproduction in HDM-induced asthma mouse model through the YAP-ROCK2 pathway.
Topics: alpha Catenin; Animals; Asthma; Disease Models, Animal; Humans; Interleukin-13; Interleukin-4; Lung; Mice; Mice, Inbred BALB C; Mucus; Pyroglyphidae; rho-Associated Kinases | 2022 |
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
Topics: Animals; Asthma; Cells, Cultured; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Hydrogels; Instillation, Drug; Mice; Microspheres; Mucus; Nanospheres; Niclosamide; Pneumonia; Polyethylene Glycols; Respiratory Mucosa; Respiratory System; SARS-CoV-2; Trachea | 2022 |
Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Humans; Inflammation; Mice; Mucin 5AC; Mucin-5B; Mucus; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa | 2022 |
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Mucins; Mucus; RNA, Ribosomal, 16S; Verrucomicrobia | 2022 |
Azithromycin inhibits mucin secretion, mucous metaplasia, airway inflammation, and airways hyperresponsiveness in mice exposed to house dust mite extract.
Topics: Adenosine Triphosphate; Allergens; Animals; Asthma; Azithromycin; Disease Models, Animal; Inflammation; Interleukin-13; Metaplasia; Methacholine Chloride; Mice; Mucins; Mucus; Pyroglyphidae | 2022 |
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Inflammation; Interleukin-33; Interleukin-4; Interleukin-5; Interleukin-9; Lung; Metaplasia; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Phenotype | 2022 |
Milk Fat Globule Membrane Attenuates Acute Colitis and Secondary Liver Injury by Improving the Mucus Barrier and Regulating the Gut Microbiota.
Topics: Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Glycolipids; Glycoproteins; Inflammatory Bowel Diseases; Intestinal Mucosa; Lipid Droplets; Liver; Mice; Mice, Inbred C57BL; Mucus; RNA, Ribosomal, 16S | 2022 |
Selective Pharmaceutical Inhibition of PARP14 Mitigates Allergen-Induced IgE and Mucus Overproduction in a Mouse Model of Pulmonary Allergic Response.
Topics: Allergens; Animals; Asthma; Disease Models, Animal; Immunoglobulin E; Mice; Mucus; Pharmaceutical Preparations; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 2022 |
Oxysophocarpine inhibits airway inflammation and mucus hypersecretion through JNK/AP-1 pathway in vivo and in vitro.
Topics: Alkaloids; Animals; Antioxidants; Asthma; Cytokines; Disease Models, Animal; Eosine Yellowish-(YS); Hematoxylin; Immunoglobulin E; Interleukin-4; Interleukin-5; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Molecular Structure; Mucins; Mucus; Ovalbumin; Periodic Acid; Quinolizidines; RNA, Messenger; Tolonium Chloride; Transcription Factor AP-1 | 2022 |
Juvenile arsenic exposure aggravates goblet cell hyperplasia and airway mucus secretion in ovalbumin-sensitized mice.
Topics: Animals; Arsenic; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Drinking Water; Female; Goblet Cells; Hyperplasia; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pregnancy | 2022 |
Topical Adenosine Inhibits Inflammation and Mucus Production in Viral Acute Rhinosinusitis.
Topics: Adenosine; Animals; Disease Models, Animal; Inflammation; Mice; Mucins; Mucus; Sinusitis | 2023 |
Modified Gegen Qinlian decoction ameliorates DSS-induced chronic colitis in mice by restoring the intestinal mucus barrier and inhibiting the activation of γδT17 cells.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Inflammasomes; Mice; Mice, Inbred C57BL; Mucus; NLR Family, Pyrin Domain-Containing 3 Protein | 2023 |
Shaoyao decoction restores the mucus layer in mice with DSS-induced colitis by regulating Notch signaling pathway.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; In Situ Hybridization, Fluorescence; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mucus; Signal Transduction; Tandem Mass Spectrometry | 2023 |
Rosmarinic Acid Restores Colonic Mucus Secretion in Colitis Mice by Regulating Gut Microbiota-Derived Metabolites and the Activation of Inflammasomes.
Topics: Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammasomes; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mucus; Rosmarinic Acid | 2023 |
LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; Colon; Disease Models, Animal; Humans; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mucus; RNA, Long Noncoding | 2023 |
Altered Secretion, Constitution, and Functional Properties of the Gastrointestinal Mucus in a Rat Model of Sporadic Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Brain; Disease Models, Animal; Goblet Cells; Mucins; Mucus; Rats | 2023 |
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Hypersensitivity; Inflammation; Interleukin-13; Lacticaseibacillus rhamnosus; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; RNA, Messenger; Transcription Factors | 2023 |
Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway.
Topics: Air Pollutants; Animals; Asthma; Benzo(a)pyrene; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Immunoglobulin E; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Reactive Oxygen Species | 2024 |
Melia azedarach L. reduces pulmonary inflammation and mucus hypersecretion on a murine model of ovalbumin exposed asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflammation; Melia azedarach; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pneumonia | 2024 |
Niclosamide repurposed for the treatment of inflammatory airway disease.
Topics: Animals; Anoctamins; Anti-Inflammatory Agents; Asthma; Bronchi; Cell Line, Tumor; Cystic Fibrosis; Disease Models, Animal; Drug Repositioning; Goblet Cells; HEK293 Cells; Humans; Mice; Mice, Knockout; Mice, Transgenic; Mucus; Niclosamide; Ovalbumin; Pulmonary Disease, Chronic Obstructive; Signal Transduction | 2019 |
Butylphthalide ameliorates airway inflammation and mucus hypersecretion via NF-κB in a murine asthma model.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Benzofurans; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Leukocyte Count; Lung; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Ovalbumin | 2019 |
Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier and immune defense defects.
Topics: Animals; Anti-Bacterial Agents; Colitis; Colon; Cytochrome b Group; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal Microbiome; Immunity, Innate; Immunity, Mucosal; Intestinal Mucosa; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mucus; Mutation, Missense; NADPH Oxidases; Reactive Oxygen Species; Signal Transduction | 2019 |
A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy.
Topics: Acrylic Resins; Adhesiveness; Animals; beta-Cyclodextrins; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Disease Models, Animal; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Mucins; Mucus; Nanogels; Paclitaxel; Solubility; Uterine Cervical Neoplasms | 2019 |
Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation.
Topics: Animals; Chronic Disease; Citrobacter rodentium; Colectomy; Colitis; Colon; Disease Models, Animal; Enterobacteriaceae Infections; Goblet Cells; Humans; Intestinal Mucosa; Mice; Mice, Knockout; Mucus; Mutation; Solute Carrier Family 12, Member 2 | 2020 |
Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2).
Topics: Animals; Asthma; Carrier Proteins; Child; Child, Preschool; Disease Models, Animal; Female; Humans; Immunity, Innate; Interleukin-33; Leukocytes, Mononuclear; Lung; Lymphocytes; Male; Mice; Mice, Knockout; Mucus; NFATC Transcription Factors; Respiratory Hypersensitivity; T-Box Domain Proteins | 2019 |
Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction.
Topics: Administration, Oral; Animals; Arachidonic Acid; Cell Line; Cystic Fibrosis; Disease Models, Animal; Docosahexaenoic Acids; Fenretinide; Humans; Lung; Mice; Mice, Inbred CFTR; Mucin 5AC; Mucin-5B; Mucus; Phospholipids; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Respiratory Mucosa | 2020 |
Systems pharmacology-based study of Tanreqing injection in airway mucus hypersecretion.
Topics: Animals; Data Analysis; Disease Models, Animal; Drugs, Chinese Herbal; Ethnopharmacology; Humans; Lipopolysaccharides; Lung; Male; Mucin 5AC; Mucus; Protein Interaction Mapping; Protein Interaction Maps; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Software; Support Vector Machine | 2020 |
Serotonin receptors 5-HTR2A and 5-HTR2B are involved in cigarette smoke-induced airway inflammation, mucus hypersecretion and airway remodeling in mice.
Topics: Airway Remodeling; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Injections, Intraperitoneal; Ketanserin; Lung; Male; Mice; Mucus; Nicotiana; Pulmonary Disease, Chronic Obstructive; Pyrimidines; Quercetin; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Respiratory Mucosa; Serotonin 5-HT2 Receptor Antagonists; Smoke; Specific Pathogen-Free Organisms | 2020 |
Rhubarb-Evoke Mucus Secretion through Aggregation and Degranulation of Mast Cell in the Colon of Rat: In vivo and ex vivo studies.
Topics: Animals; Cell Aggregation; Cell Degranulation; Colon; Cytokines; Digestive System; Disease Models, Animal; Drugs, Chinese Herbal; Exocytosis; Humans; Mast Cells; Mucus; Rats; Rheum | 2019 |
Iloprost inhibits acute allergic nasal inflammation by GATA3 -ILC2 pathway in mice.
Topics: Animals; Disease Models, Animal; Female; GATA3 Transcription Factor; Goblet Cells; Hyperplasia; Iloprost; Interleukin-1 Receptor-Like 1 Protein; Interleukin-13; Interleukin-33; Interleukin-5; Lung; Lymphocytes; Mice; Mucus; Nasal Mucosa; Random Allocation; Respiratory Mucosa; Rhinitis, Allergic; RNA, Messenger; Trachea | 2020 |
Intravital microscopic optical coherence tomography imaging to assess mucus-mobilizing interventions for muco-obstructive lung disease in mice.
Topics: Animals; Disease Models, Animal; Epithelial Sodium Channels; Humans; Intravital Microscopy; Lung Diseases, Obstructive; Mice; Mice, Transgenic; Mucociliary Clearance; Mucus; Tomography, Optical Coherence | 2020 |
LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus.
Topics: Animals; Antibodies, Bacterial; Disease Models, Animal; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Intestinal Mucosa; Lipopolysaccharides; Mice; Mucus; Polysaccharides; Protein Binding; Salmonella Infections; Salmonella typhimurium | 2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Airway Obstruction; Animals; Animals, Newborn; Bicarbonates; Bronchi; Bronchoalveolar Lavage Fluid; Chlorides; Cystic Fibrosis; Diminazene; Disease Models, Animal; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; Male; Mucin 5AC; Mucin-5B; Mucociliary Clearance; Mucus; Respiratory Mucosa; Swine; Trachea | 2020 |
Warifteine and methylwarifteine inhibited the type 2 immune response on combined allergic rhinitis and asthma syndrome (CARAS) experimental model through NF-кB pathway.
Topics: Alkaloids; Animals; Anti-Allergic Agents; Asthma; Behavior, Animal; Bronchoalveolar Lavage Fluid; Cissampelos; Collagen; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Inflammation; Lung; Mast Cells; Mice, Inbred BALB C; Mucus; Nasal Lavage Fluid; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic; Signal Transduction; Sneezing; Transcription Factor RelA | 2020 |
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Disease Models, Animal; Female; Humans; I-kappa B Kinase; Immunoglobulin E; Inflammation; Lung; Male; Mice, Inbred C57BL; Mucin 5AC; Mucus; NF-kappa B; Ovalbumin; Panax notoginseng; Pyroglyphidae; Respiratory Hypersensitivity; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Ursolic Acid Alleviates Mucus Secretion and Tissue Remodeling in Rat Model of Allergic Rhinitis After PM2.5 Exposure.
Topics: Animals; Disease Models, Animal; Mucus; Nasal Mucosa; Ovalbumin; Particulate Matter; Rats; Rhinitis, Allergic; Triterpenes; Ursolic Acid | 2021 |
The establishment of humanized IL-4/IL-4RA mouse model by gene editing and efficacy evaluation.
Topics: Allergens; Animals; Antibodies, Monoclonal; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Female; Gene Editing; Goblet Cells; Humans; Immunoglobulin E; Interleukin-4; Interleukin-4 Receptor alpha Subunit; Leukocytes; Lung; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mucus; Ovalbumin; Spleen | 2020 |
Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa.
Topics: Animals; Corynebacterium; Cytokines; Disease Models, Animal; Enterobacter aerogenes; Epithelial Cells; Female; Gene Expression; Humans; Immunity, Innate; Interleukin-33; Mice, Inbred BALB C; Micrococcus luteus; Mucus; Nasal Mucosa; Ovalbumin; Primary Cell Culture; Rhinitis, Allergic; RNA, Messenger; Staphylococcus aureus; Staphylococcus epidermidis; Symbiosis | 2020 |
Pulmonary Mycosis Drives Forkhead Box Protein A2 Degradation and Mucus Hypersecretion through Activation of the Spleen Tyrosine Kinase-Epidermal Growth Factor Receptor-AKT/Extracellular Signal-Regulated Kinase 1/2 Signaling.
Topics: Animals; Blastomycosis; Cats; Disease Models, Animal; Dogs; ErbB Receptors; Hepatocyte Nuclear Factor 3-beta; Histoplasma; Histoplasmosis; Lung Diseases, Fungal; MAP Kinase Signaling System; Mucus; Proto-Oncogene Proteins c-akt; Signal Transduction; Syk Kinase | 2021 |
Copaifera malmei Harms leaves infusion attenuates TNBS-ulcerative colitis through modulation of cytokines, oxidative stress and mucus in experimental rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Fabaceae; Inflammation Mediators; Male; Mucus; Oxidative Stress; Plant Extracts; Plant Leaves; Rats, Wistar; Signal Transduction; Trinitrobenzenesulfonic Acid | 2021 |
Mitoquinone ameliorates cigarette smoke-induced airway inflammation and mucus hypersecretion in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Inflammation Mediators; Lung; Male; Mice, Inbred C57BL; Mitochondria; Mucus; NF-kappa B; Organophosphorus Compounds; Oxidative Stress; Pneumonia; Secretory Pathway; Signal Transduction; Smoke; Tobacco Products; Ubiquinone | 2021 |
TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway inflammation in an OVA-induced mouse asthma model.
Topics: Acupuncture Therapy; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Fusion Regulatory Protein 1, Heavy Chain; Inflammation; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Proteomics; Respiratory Hypersensitivity; Sodium-Potassium-Exchanging ATPase | 2021 |
Dilodendron bipinnatum Radlk. extract alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration, TNF-α and IL-1β concentrations, IL-17 and COX-2 expressions, supporting mucus production and promotes an antioxidant ef
Topics: Animals; Antioxidants; Brazil; Caco-2 Cells; Cell Survival; Colitis, Ulcerative; Cyclooxygenase 2; Disease Models, Animal; Edema; Glutathione; Humans; Interleukin-17; Interleukin-1beta; Interleukin-8; Lipopolysaccharides; Mast Cells; Mucus; Peroxidase; Plant Bark; Plant Extracts; Rats, Wistar; Sapindaceae; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2021 |
Disulfide disruption reverses mucus dysfunction in allergic airway disease.
Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Disulfides; Expectorants; Female; Glycoproteins; Humans; Hypersensitivity; Lung; Male; Mice; Mice, Inbred BALB C; Middle Aged; Mucus | 2021 |
Long non-coding RNA TUG1 promotes airway remodeling and mucus production in asthmatic mice through the microRNA-181b/HMGB1 axis.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Cells, Cultured; Disease Models, Animal; Female; HMGB1 Protein; Lung; Mice, Inbred BALB C; MicroRNAs; Mucus; NF-kappa B; Ovalbumin; RNA, Long Noncoding; Signal Transduction | 2021 |
Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma.
Topics: Animals; Asthma; Disease Models, Animal; Mice; Mucus; Polyporaceae; Th2 Cells | 2021 |
Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult
Topics: Animals; Cathepsins; Cystic Fibrosis; Disease Models, Animal; Epithelial Sodium Channels; Inflammation; Lung; Mice; Mice, Transgenic; Mucus | 2021 |
Mainstream Cigarette Smoke Impacts the Mouse Vocal Fold Epithelium and Mucus Barrier.
Topics: Adult; Animals; Cigarette Smoking; Disease Models, Animal; Epithelium; Female; Humans; Laryngeal Mucosa; Laryngoscopy; Male; Mice; Mucins; Mucus; Nicotiana; Non-Smokers; Smoke; Smokers; Toxicity Tests, Subacute; Vocal Cords; Young Adult | 2021 |
Tectochrysin ameliorates murine allergic airway inflammation by suppressing Th2 response and oxidative stress.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Basophils; Catalase; Disease Models, Animal; Eosinophils; Female; Flavonoids; Glutathione Peroxidase; Hypersensitivity; Immunoglobulin E; Injections, Intraperitoneal; Mice, Inbred C57BL; Mucus; Oxidative Stress; Shellfish Hypersensitivity; Th2 Cells; Tropomyosin | 2021 |
VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway.
Topics: Airway Obstruction; Animals; Cell Transdifferentiation; Disease Models, Animal; Gene Expression Regulation; Goblet Cells; Humans; Interleukin-13; MAP Kinase Signaling System; Metaplasia; Mice; Mucus; Single-Cell Analysis; SOX9 Transcription Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2021 |
sRAGE Inhibits the Mucus Hypersecretion in a Mouse Model with Neutrophilic Asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Glycosylation; HMGB1 Protein; Inflammation; Lung; Mice; Mucus; Neutrophils; Phosphatidylinositol 3-Kinases; Receptor for Advanced Glycation End Products | 2022 |
Casein-fed mice showed faster recovery from DSS-induced colitis than chicken-protein-fed mice.
Topics: Animals; Bacteria; Body Weight; Caseins; Chickens; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Mucin-2; Mucus; Proteins; RNA, Ribosomal, 16S; Spleen; Tumor Necrosis Factor-alpha | 2021 |
Epithelium-derived IL17A Promotes Cigarette Smoke-induced Inflammation and Mucus Hyperproduction.
Topics: Animals; Cell Line; Cigarette Smoking; Disease Models, Animal; Humans; Inflammation; Interleukin-17; Mice; Mice, Knockout; Mucus; Neutrophil Infiltration; Neutrophils; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa | 2021 |
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
Topics: Amino Acid Sequence; Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Endoplasmic Reticulum Stress; Gastric Mucosa; Genetic Predisposition to Disease; Goblet Cells; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice, Knockout; Mucins; Mucoproteins; Mucus; Oncogene Proteins; Phenotype; Sequence Analysis, DNA; Siblings; Structure-Activity Relationship; Whole Genome Sequencing | 2021 |
Postnatal Ozone Exposure Disrupts Alveolar Development, Exaggerates Mucoinflammatory Responses, and Suppresses Bacterial Clearance in Developing
Topics: Animals; Bacteria; Cystic Fibrosis; Disease Models, Animal; Epithelial Sodium Channels; Inflammation; Lung; Macrophages; Mice; Mice, Transgenic; Mucus; Ozone; Postnatal Care | 2021 |
IRE1β does not affect mucus secretion during allergic asthma development in a house dust mite murine model.
Topics: Allergens; Animals; Asthma; Disease Models, Animal; Humans; Mice; Mucus; Pyroglyphidae | 2021 |
Nattokinase, profibrinolytic enzyme, effectively shrinks the nasal polyp tissue and decreases viscosity of mucus.
Topics: Adult; Aged; Animals; Asthma; Chronic Disease; Disease Models, Animal; Eosinophils; Female; Fibrin; Humans; Immunoglobulin E; Leukocyte Count; Male; Mice; Middle Aged; Mucus; Nasal Mucosa; Nasal Polyps; Proteolysis; Rhinitis; Sinusitis; Subtilisins; Viscosity | 2017 |
Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients.
Topics: Animals; Asthma; Disease Models, Animal; Epithelial Cells; Humans; Immunity, Innate; Interleukin-13; Lymphocyte Subsets; Mice; Mice, Transgenic; Mucus; Respiratory Mucosa; Tight Junctions | 2018 |
Anti‑inflammatory effects of dihydromyricetin in a mouse model of asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Flavonols; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Mice; Mucus; Ovalbumin | 2017 |
Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Chloroquine; Cytokines; Disease Models, Animal; Female; Humans; Hypersensitivity; Immunization; Inflammation; Lung; Matrix Metalloproteinases; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Neutrophils; Pyroglyphidae; Quinine; Receptors, G-Protein-Coupled; Taste | 2017 |
BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Topics: Airway Remodeling; Airway Resistance; Animals; ARNTL Transcription Factors; Asthma; Bronchiolitis, Viral; Circadian Clocks; Cohort Studies; Disease Models, Animal; Humans; Influenza A virus; Mice; Mice, Knockout; Mucus; Orthomyxoviridae Infections; Respirovirus Infections; Sendai virus; Virus Replication | 2018 |
The Immunotherapeutic Role of Bacterial Lysates in a Mouse Model of Asthma.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cell Extracts; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Immunotherapy; Lung; Mice; Mucus; Neutrophils; Th1 Cells; Th2 Cells | 2017 |
Compositional Changes in the Gut Mucus Microbiota Precede the Onset of Colitis-Induced Inflammation.
Topics: Animals; Bacteria; Colitis; Colon; Disease Models, Animal; DNA, Bacterial; Dysbiosis; Feces; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Knockout; Mucus; RNA, Ribosomal, 16S | 2017 |
Isoimperatorin attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Disease Models, Animal; Female; Furocoumarins; Humans; Immunoglobulin E; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 3; Mucus; NF-kappa B; Ovalbumin; p38 Mitogen-Activated Protein Kinases; Pneumonia; Signal Transduction; Th2 Cells | 2017 |
Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease.
Topics: Animals; Animals, Newborn; Bacterial Infections; Bacterial Load; Cell Movement; Cystic Fibrosis; Disease Models, Animal; Down-Regulation; Epithelial Cells; Epithelial Sodium Channels; Female; Goblet Cells; Humans; Immunoglobulin A; Interleukin-33; Lung; Lung Diseases, Obstructive; Mice; Mice, Transgenic; Mucin-5B; Mucus; Neutrophils; Signal Transduction; Th2 Cells; Tobacco Smoke Pollution | 2017 |
Therapeutic intranasal instillation of allergen-loaded microbubbles suppresses experimental allergic asthma in mice.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Allergens; Animals; Antibody Formation; Asthma; Disease Models, Animal; Female; Immunization; Immunoglobulin A; Immunoglobulin E; Immunomodulation; Mice, Inbred BALB C; Microbubbles; Mucus; Ovalbumin; Pneumonia; Th2 Cells | 2017 |
Pidotimod exacerbates allergic pulmonary infection in an OVA mouse model of asthma.
Topics: Animals; Arginase; Asthma; Bronchoalveolar Lavage Fluid; Cell Differentiation; Disease Models, Animal; Down-Regulation; Eosinophils; Female; Hypersensitivity; Immunoglobulin E; Intercellular Signaling Peptides and Proteins; Lung; Metaplasia; Mice, Inbred C57BL; Mucus; Ovalbumin; Pyrrolidonecarboxylic Acid; Respiratory Tract Infections; Th2 Cells; Thiazolidines | 2017 |
Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Histocytochemistry; Hydrogen; Injections, Intraperitoneal; Male; Mucin 5AC; Mucus; Pulmonary Disease, Chronic Obstructive; Rats, Sprague-Dawley; Respiratory Function Tests; Smoke; Sodium Chloride; Treatment Outcome | 2017 |
Capsule Type and Amount Affect Shedding and Transmission of
Topics: Animals; Animals, Newborn; Bacterial Capsules; Bacterial Shedding; Disease Models, Animal; Host-Pathogen Interactions; Mice; Mucus; Mutation; Nose; Pneumococcal Infections; Polysaccharides, Bacterial; Respiratory Tract Infections; Streptococcus pneumoniae | 2017 |
Limax extract ameliorates cigarette smoke-induced chronic obstructive pulmonary disease in mice.
Topics: Animals; Cigarette Smoking; Complex Mixtures; Cytokines; Disease Models, Animal; Gastropoda; Humans; Mice; Mice, Inbred C57BL; Mucin 5AC; Mucin-5B; Mucus; Pneumonia; Pulmonary Disease, Chronic Obstructive | 2018 |
Progression of Type 2 Helper T Cell-Type Inflammation and Airway Remodeling in a Rodent Model of Naturally Acquired Subclinical Primary Pneumocystis Infection.
Topics: Animals; Bronchioles; Disease Models, Animal; Disease Progression; Extracellular Matrix; Female; Gene Expression Regulation; Immunocompetence; Inflammation Mediators; Mucus; NF-kappa B; Pneumonia, Pneumocystis; Rats, Sprague-Dawley; Respiratory Mucosa; RNA, Messenger; Signal Transduction; Th2 Cells | 2018 |
Phloretin attenuates mucus hypersecretion and airway inflammation induced by cigarette smoke.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cigarette Smoking; Disease Models, Animal; ErbB Receptors; Humans; Interleukin-1beta; Lung; Male; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; p38 Mitogen-Activated Protein Kinases; Phloretin; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Development of an airway mucus defect in the cystic fibrosis rat.
Topics: Animals; Bicarbonates; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Gene Knockout Techniques; Ion Transport; Male; Mucociliary Clearance; Mucus; Rats; Respiratory Mucosa; Surface Properties | 2018 |
Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium.
Topics: Animals; Apoptosis; Bronchi; Cell Line; Cytokines; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Epithelial Cells; Heat-Shock Proteins; Humans; Imidazoles; Indoles; Inflammation Mediators; Lung Injury; Mice, Inbred C57BL; Mucin 5AC; Mucus; Necrosis; NF-kappa B; Pneumonia; RNA Interference; Signal Transduction; Smoke; Smoking; Time Factors; Transcription Factor AP-1; Transfection | 2018 |
Effects of ozone repeated short exposures on the airway/lung inflammation, airway hyperresponsiveness and mucus production in a mouse model of ovalbumin-induced asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-13; Interleukin-1beta; Interleukin-4; Male; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Oxidative Stress; Ozone; Pneumonia; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2018 |
Bacillus subtilis spore with surface display of paramyosin from Clonorchis sinensis potentializes a promising oral vaccine candidate.
Topics: Administration, Oral; Animals; Antibodies, Helminth; Bacillus subtilis; Bile; Blood Chemical Analysis; Cell Surface Display Techniques; Clonorchiasis; Clonorchis sinensis; Disease Models, Animal; Drug Carriers; Feces; Histocytochemistry; Immunoglobulin A, Secretory; Injections, Intraperitoneal; Intestinal Mucosa; Intestines; Liver Cirrhosis; Mice, Inbred BALB C; Mucus; Parasite Egg Count; Spores, Bacterial; Treatment Outcome; Tropomyosin; Vaccines, Synthetic | 2018 |
LPS Exposure in Early Life Protects Against Mucus Hypersecretion in Ovalbumin-Induced Asthma by Down-Regulation of the IL-13 and JAK-STAT6 Pathways.
Topics: Administration, Intranasal; Animals; Asthma; Cell Line; Disease Models, Animal; Down-Regulation; Humans; Interleukin-13; Janus Kinases; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; Ovalbumin; Protective Agents; Signal Transduction; STAT6 Transcription Factor | 2018 |
In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Lipopolysaccharides; Male; Mucin 5AC; Mucus; Pneumonia; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA, Messenger; Thymol | 2018 |
The mucus bundles responsible for airway cleaning are retained in cystic fibrosis and by cholinergic stimulation.
Topics: Animals; Cholinergic Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Cells; Humans; Mucociliary Clearance; Mucus; Pseudomonas aeruginosa; Respiratory Mucosa; Swine | 2018 |
Peroxisome proliferator-activated receptor gamma activation promotes intestinal barrier function by improving mucus and tight junctions in a mouse colitis model.
Topics: Animals; Caco-2 Cells; Colitis; Dextran Sulfate; Disease Models, Animal; HT29 Cells; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mucin-2; Mucus; Myosin-Light-Chain Kinase; Permeability; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Tight Junctions | 2018 |
TRPC1 intensifies house dust mite-induced airway remodeling by facilitating epithelial-to-mesenchymal transition and STAT3/NF-κB signaling.
Topics: Airway Remodeling; Animals; Bronchi; Calcium; Collagen; Disease Models, Animal; Down-Regulation; Epithelial Cells; Epithelial-Mesenchymal Transition; Hypersensitivity; Inflammation; Ion Transport; Mice; Mice, Knockout; Mucus; NF-kappa B; Pyroglyphidae; Signal Transduction; STAT3 Transcription Factor; TRPC Cation Channels | 2019 |
Antisense oligonucleotide targeting of mRNAs encoding ENaC subunits α, β, and γ improves cystic fibrosis-like disease in mice.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channels; Gene Targeting; Ion Transport; Lung; Mice; Mucus; Oligonucleotides, Antisense; RNA, Messenger; Sodium | 2019 |
An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.
Topics: Airway Remodeling; Airway Resistance; Animals; Asthma; Bronchi; Cell Count; Disease Models, Animal; Epithelial Cells; Epoxide Hydrolases; Extracellular Matrix; Humans; Hypersensitivity; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; Mucus; Neutrophils; Oligopeptides; Proline; Pyroglyphidae; Respiratory Hypersensitivity; Sputum; T-Lymphocytes, Helper-Inducer | 2018 |
Attached stratified mucus separates bacteria from the epithelial cells in COPD lungs.
Topics: Animals; Bacteria; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Disease Models, Animal; Epithelial Cells; Female; Humans; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucin-5B; Mucus; Pancreatic Elastase; Pseudomonas aeruginosa; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa | 2018 |
An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases.
Topics: Acetylcysteine; Animals; Asthma; Cystic Fibrosis; Disease Models, Animal; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Male; Mice; Mucociliary Clearance; Mucus; Pulmonary Disease, Chronic Obstructive | 2019 |
FOXA2 depletion leads to mucus hypersecretion in canine airways with respiratory diseases.
Topics: Animals; Bordetella Infections; Bronchitis; Disease Models, Animal; Dogs; Goblet Cells; Hepatocyte Nuclear Factor 3-beta; Mucus; Pseudomonas Infections; Respiratory Mucosa; Virus Diseases | 2019 |
Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner.
Topics: Animals; Antibodies, Blocking; Asthma; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Fos-Related Antigen-2; Humans; Interleukin-13; Lung; Mice; Mice, Transgenic; Mucus; Myocytes, Smooth Muscle; Th2 Cells; Tissue Array Analysis; Transcription Factor AP-1 | 2018 |
Akkermansia muciniphila strain ATCC BAA-835 does not promote short-term intestinal inflammation in gnotobiotic interleukin-10-deficient mice.
Topics: Animals; Body Weight; Cecum; Disease Models, Animal; Escherichia coli; Gastrointestinal Microbiome; Germ-Free Life; Humans; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-10; Intestines; Male; Mice; Mice, Knockout; Mucus; Verrucomicrobia | 2019 |
Petiveria alliacea Suppresses Airway Inflammation and Allergen-Specific Th2 Responses in Ovalbumin-Sensitized Murine Model of Asthma.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokines; Disease Models, Animal; Immunoglobulin E; Inflammation; Lung; Male; Methanol; Mice, Inbred BALB C; Mucus; Ovalbumin; Phytolaccaceae; Phytotherapy; Plant Extracts; Reactive Oxygen Species; Th2 Cells | 2018 |
Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis.
Topics: Animals; Animals, Outbred Strains; Citrobacter rodentium; Colitis; Colon; Dibenzazepines; Disease Models, Animal; Dysbiosis; Enterobacteriaceae Infections; Enzyme Inhibitors; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mucus; Receptors, Notch; Signal Transduction; Tight Junctions | 2018 |
Pulmonary Neuroendocrine Cells Secrete γ-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models.
Topics: Acute Lung Injury; Animals; Asthma; Bronchi; Disease Models, Animal; Epithelial Cells; gamma-Aminobutyric Acid; Goblet Cells; Humans; Hyperplasia; Interleukin-13; Lung; Macaca mulatta; Mucus; Neuroendocrine Cells; Receptors, GABA; Signal Transduction | 2019 |
S-Allyl cysteine reduces eosinophilic airway inflammation and mucus overproduction on ovalbumin-induced allergic asthma model.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cysteine; Cytokines; Disease Models, Animal; Eosinophilia; Female; Immunoglobulin E; Lung; Mice, Inbred BALB C; Mucus; Ovalbumin | 2019 |
Targeting of cathepsin S reduces cystic fibrosis-like lung disease.
Topics: Airway Obstruction; Animals; Cathepsins; Cystic Fibrosis; Disease Models, Animal; Epithelial Sodium Channels; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Pneumonia; Receptor, PAR-2 | 2019 |
Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia.
Topics: Airway Management; Animals; Disease Models, Animal; Female; Intubation, Intratracheal; Mucus; Peak Expiratory Flow Rate; Pneumonia, Bacterial; Prospective Studies; Pseudomonas aeruginosa; Pulmonary Gas Exchange; Respiration, Artificial; Respiratory Mechanics; Sus scrofa; Swine | 2019 |
A model of clinical endometritis in Holstein heifers using pathogenic Escherichia coli and Trueperella pyogenes.
Topics: Actinomycetaceae; Actinomycetales Infections; Animals; Body Fluids; Cattle; Cattle Diseases; Disease Models, Animal; Endometritis; Endometrium; Escherichia coli; Escherichia coli Infections; Female; Mucus; Puerperal Disorders; RNA, Ribosomal, 16S; Ultrasonography; Uterine Diseases; Uterus; Vagina; Vaginal Discharge | 2019 |
Physalis peruviana L. inhibits ovalbumin‑induced airway inflammation by attenuating the activation of NF‑κB and inflammatory molecules.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemokine CCL2; Disease Models, Animal; Down-Regulation; Enzyme Activation; Eosinophils; Female; Heme Oxygenase (Decyclizing); Immunoglobulin E; Inflammation; JNK Mitogen-Activated Protein Kinases; Lung; Macrophages; Mice; Mice, Inbred BALB C; Mucus; NF-kappa B; Ovalbumin; p38 Mitogen-Activated Protein Kinases; Physalis; Plant Extracts; RAW 264.7 Cells | 2019 |
A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Ferrets; Glucosamine; Humans; Mice; Mice, Inbred CFTR; Mucin-5B; Mucociliary Clearance; Mucus; Polymers; Protein Structure, Quaternary; Rats; Respiratory Mucosa; Viscosity | 2019 |
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Animals; Asthma; Bronchial Hyperreactivity; Crystallization; Disease Models, Animal; Glycoproteins; Goblet Cells; Humans; Immunity, Innate; Immunodominant Epitopes; Immunoglobulin E; Lysophospholipase; Metaplasia; Mice; Mice, Inbred C57BL; Mucus | 2019 |
Rho-kinase inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Down-Regulation; Female; Inflammation; Interleukin-13; JNK Mitogen-Activated Protein Kinases; Mice, Inbred C57BL; Mucus; Protein Kinase Inhibitors; Pyroglyphidae; Respiratory Hypersensitivity; rho-Associated Kinases; Signal Transduction; Transcription Factor AP-1 | 2019 |
Food Polyelectrolytes Compress the Colonic Mucus Hydrogel by a Donnan Mechanism.
Topics: Animals; Bacterial Infections; Biofilms; Carboxymethylcellulose Sodium; Colon; Disease Models, Animal; Glycoproteins; Host-Pathogen Interactions; Humans; Hydrogels; Inflammation; Mice; Mucus; Obesity; Polyelectrolytes; Polymers | 2019 |
ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Child; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Interleukin-13; Interleukin-4; Interleukin-5; Lung; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mucus; Ovalbumin; Respiratory Function Tests; Respiratory Hypersensitivity; Signal Transduction | 2019 |
Anti-inflammatory activity of SintMed65, an N-acylhydrazone derivative, in a mouse model of allergic airway inflammation.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hydrazones; Leukocyte Count; Lung; Male; Mice, Inbred BALB C; Mucus; Ovalbumin | 2019 |
Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial
Topics: Acids; Animals; Autophagy; Bacterial Proteins; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Enterocytes; Epithelium; Humans; Inflammatory Bowel Diseases; Intestines; Lysosomes; Models, Biological; Mucins; Mucus; Zebrafish | 2019 |
Dendritic polyglycerolsulfate near infrared fluorescent (NIRF) dye conjugate for non-invasively monitoring of inflammation in an allergic asthma mouse model.
Topics: Animals; Asthma; Disease Models, Animal; Female; Fluorescent Dyes; Glycerol; Immunoglobulin G; Inflammation; Lung; Mice; Mucus; Optical Imaging; Ovalbumin; Polymers; Spectroscopy, Near-Infrared; Sulfates; Time Factors | 2013 |
Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice.
Topics: Airway Remodeling; Aldehyde Reductase; Animals; Asthma; Biomarkers; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypersensitivity; Imidazolidines; Inflammation; Lung; Metaplasia; Mice; Mucus; Ovalbumin; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2013 |
Pinellia ternata Breitenbach attenuates ovalbumin-induced allergic airway inflammation and mucus secretion in a murine model of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Immunoglobulin E; Inflammation; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pinellia; Respiratory System | 2013 |
Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease.
Topics: Age Factors; Animals; Animals, Newborn; Chemotaxis; Disease Models, Animal; Epithelial Sodium Channels; Gene Expression; Inflammation; Keratinocytes; Lung; Mice; Mucus; Neutrophils; Pulmonary Disease, Chronic Obstructive; Saline Solution, Hypertonic | 2013 |
Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model.
Topics: Animals; Anti-Asthmatic Agents; Artemisinins; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Goblet Cells; Immunoglobulin E; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Respiratory Hypersensitivity; Respiratory System; Th2 Cells | 2013 |
Beneficial role of the probiotic mixture Ultrabiotique on maintaining the integrity of intestinal mucosal barrier in DSS-induced experimental colitis.
Topics: Animals; Bifidobacterium; Colitis, Ulcerative; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Goblet Cells; Intestinal Mucosa; Lactobacillus; Macrophages; Male; Mice; Mucus; Nitric Oxide; Probiotics | 2013 |
Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent.
Topics: Acetates; Animals; Bacteroides; Bacteroides Infections; Cell Differentiation; Colon; Disease Models, Animal; Gene Expression Regulation; Germ-Free Life; Glycosylation; Goblet Cells; Gram-Positive Bacterial Infections; Host-Pathogen Interactions; HT29 Cells; Humans; Intestinal Mucosa; Kruppel-Like Factor 4; Mucus; Polysaccharides; Rats; Ruminococcus; Signal Transduction; Time Factors | 2013 |
Divergent immune responses to Mycobacterium avium subsp. paratuberculosis infection correlate with kinome responses at the site of intestinal infection.
Topics: Animals; Cattle; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Host-Pathogen Interactions; Humans; Immunity, Innate; Intestinal Mucosa; Intestines; Microarray Analysis; Mucus; Mycobacterium avium subsp. paratuberculosis; Paratuberculosis; Phosphotransferases; Transcriptome | 2013 |
A respiratory syncytial virus (RSV) anti-G protein F(ab')2 monoclonal antibody suppresses mucous production and breathing effort in RSV rA2-line19F-infected BALB/c mice.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Viral; Chemoprevention; Disease Models, Animal; Female; Immunoglobulin Fab Fragments; Mice; Mice, Inbred BALB C; Mucus; Respiration; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory System; Respiratory Tract Infections; Treatment Outcome | 2013 |
Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.
Topics: Animals; Animals, Newborn; Antibodies, Neutralizing; Apoptosis; Chlamydia Infections; Chlamydia muridarum; Disease Models, Animal; Disease Progression; Gene Expression; Mice; Mice, Knockout; Mucus; NF-kappa B; Pneumonia; Pulmonary Alveoli; Receptors, TNF-Related Apoptosis-Inducing Ligand; Respiratory Hypersensitivity; Respiratory Tract Infections; TNF-Related Apoptosis-Inducing Ligand | 2014 |
Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice.
Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Female; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Mucus; Recurrence; Scopolamine Derivatives; Tiotropium Bromide | 2014 |
Effects of montelukast on subepithelial/peribronchial fibrosis in a murine model of ovalbumin induced chronic asthma.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Leukotriene Antagonists; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pulmonary Fibrosis; Quinolines; Smad3 Protein; Sulfides; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2013 |
Mast cell-deficient kit mice develop house dust mite-induced lung inflammation despite impaired eosinophil recruitment.
Topics: Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Disease Models, Animal; Eosinophils; Humans; Immunoglobulin E; Immunohistochemistry; Lung; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Ovalbumin; Pneumonia; Proto-Oncogene Proteins c-kit; Pyroglyphidae; Tryptases | 2014 |
Early-life exposure to combustion-derived particulate matter causes pulmonary immunosuppression.
Topics: Adoptive Transfer; Allergens; Animals; Animals, Newborn; Antigens; Asthma; Dendritic Cells; Disease Models, Animal; Environmental Exposure; Immunosuppression Therapy; Lung; Mice; Mucus; Particulate Matter; Respiratory Hypersensitivity; T-Lymphocytes, Regulatory; Th2 Cells | 2014 |
REG3γ-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum.
Topics: Animals; Disease Models, Animal; Gene Expression Profiling; Ileum; Immunity, Innate; Inflammation; Interferon Regulatory Factors; Interferons; Interleukin-1beta; Intestinal Mucosa; Listeria monocytogenes; Mice; Mice, Knockout; Microbiota; Mucus; Myeloid Differentiation Factor 88; Pancreatitis-Associated Proteins; Proteins; Salmonella enteritidis; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Toll-Like Receptor 3 | 2014 |
γδ T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer.
Topics: Animals; Antigens, Surface; Colitis; Dextran Sulfate; Disease Models, Animal; Epidermal Growth Factor; Gene Expression Regulation; Glycosylation; Goblet Cells; Homeostasis; Immunity, Mucosal; Intestine, Small; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucin-2; Mucins; Mucus; Organoids; Receptors, Antigen, T-Cell, gamma-delta; Time Factors; Tissue Culture Techniques | 2014 |
Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Differentiation; Chronic Disease; Cytokines; Disease Models, Animal; Female; Fibrosis; Flavanones; Immunoglobulin E; Inflammation; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Th2 Cells | 2014 |
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
Topics: Airway Obstruction; Animals; Bronchiectasis; Cystic Fibrosis; Disease Models, Animal; Epithelial Sodium Channels; Gene Deletion; Humans; Inflammation; Kaplan-Meier Estimate; Leukocyte Elastase; Lung; Mice; Mucus; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sputum | 2014 |
Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model.
Topics: Animals; Disease Models, Animal; Humans; Lung; Male; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Mucus; Ovalbumin; Phenotype; Polymorphism, Single Nucleotide; Pulmonary Surfactant-Associated Protein D; Respiratory Hypersensitivity; Respiratory Mucosa | 2014 |
Treatment with the C5a receptor/CD88 antagonist PMX205 reduces inflammation in a murine model of allergic asthma.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Epithelial Cells; Female; Goblet Cells; Immunoglobulin E; Inflammation; Interleukin-13; Lung; Male; Mice; Mice, Inbred BALB C; Mucus; Neutrophils; Ovalbumin; Peptides, Cyclic; Receptor, Anaphylatoxin C5a; Th2 Cells | 2014 |
The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Disease Models, Animal; Disease Progression; Ileum; Male; Mucus; Oxidative Stress; Pancreatitis; Permeability; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; Reperfusion Injury; Splanchnic Circulation; Time Factors | 2014 |
Siegesbeckia glabrescens attenuates allergic airway inflammation in LPS-stimulated RAW 264.7 cells and OVA induced asthma murine model.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line; Cell Survival; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Mucus; Nitric Oxide; Nitric Oxide Synthase Type II; Ovalbumin; Phytotherapy; Plant Preparations | 2014 |
Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation.
Topics: Airway Remodeling; Animals; Apoptosis Regulatory Proteins; Arginase; Asthma; beta-N-Acetylhexosaminidases; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Line; Disease Models, Animal; Gene Expression Regulation; Lung; Macrophage Activation; Macrophages, Alveolar; Mucus; Nerve Growth Factor; Ovalbumin; Rats; RNA Interference; RNA, Small Interfering; Spleen; Transforming Growth Factor beta1 | 2014 |
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.
Topics: Animals; Animals, Newborn; Anions; Cilia; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Exocrine Glands; Lung; Methacholine Chloride; Mucociliary Clearance; Mucus; Respiratory Mucosa; Respiratory System; Swine; Trachea | 2014 |
Airway remodeling is reversed by aerobic training in a murine model of chronic asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cell Movement; Chemokine CCL5; Chemokines, CC; Chronic Disease; Collagen; Disease Models, Animal; Elastic Tissue; Eosinophils; Intercellular Adhesion Molecule-1; Interleukin-5; Leukocytes; Macrophages, Alveolar; Mice; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Osteopontin; Ovalbumin; Physical Conditioning, Animal; Respiratory Mucosa; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2015 |
Melatonin reduces airway inflammation in ovalbumin-induced asthma.
Topics: Animals; Antibody Formation; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cytokines; Disease Models, Animal; Enzyme Activation; Female; Immunoglobulin E; Inflammation; Inflammation Mediators; Matrix Metalloproteinase 9; Melatonin; Mucus; Ovalbumin; Tumor Necrosis Factor-alpha | 2014 |
Melatonin attenuates neutrophil inflammation and mucus secretion in cigarette smoke-induced chronic obstructive pulmonary diseases via the suppression of Erk-Sp1 signaling.
Topics: Animals; Antioxidants; Cell Line, Tumor; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Melatonin; Mice; Mucus; Neutrophil Infiltration; Neutrophils; Pulmonary Disease, Chronic Obstructive; Rats; Smoking; Sp1 Transcription Factor | 2015 |
Healing process in mice model of surgical wounds enhanced by Phyllocaulis boraceiensis mucus.
Topics: Animals; Biological Products; Cell Proliferation; Disease Models, Animal; Female; Gastropoda; Mice; Mice, Inbred BALB C; Mucus; Ointments; Skin; Time Factors; Wound Healing; Wounds and Injuries | 2014 |
Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Disease Models, Animal; Eosinophils; Female; Goblet Cells; HMGB1 Protein; Hyperplasia; Immunoglobulin E; Inflammation; Interleukin-10; Lung; Lymphocyte Count; Macrophages; Methyl Ethers; Mice; Mice, Inbred C57BL; Mucus; Neutrophils; Ovalbumin; Sevoflurane; Tumor Necrosis Factor-alpha | 2015 |
Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Enzyme Activation; Eosinophils; Immunoglobulin E; Inflammation; Lung; Male; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pulmonary Eosinophilia; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists | 2015 |
Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Caribbean Region; Disease Models, Animal; Ethanol; Gastric Juice; Gastric Mucosa; Helicobacter pylori; Male; Microbial Sensitivity Tests; Mucus; Nitric Oxide; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats, Wistar; Reperfusion Injury; Stomach Ulcer; Terminalia | 2015 |
Lipoxin B₄ promotes the resolution of allergic inflammation in the upper and lower airways of mice.
Topics: Animals; Cell Degranulation; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Inflammation; Leukocytes; Lipoxins; Lung; Male; Mast Cells; Mice; Mucus; Nasal Mucosa; Respiratory Hypersensitivity | 2015 |
Triptolide suppresses airway goblet cell hyperplasia and Muc5ac expression via NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Goblet Cells; Hyperplasia; Hypertrophy; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Phenanthrenes; Phosphorylation; RNA, Messenger; Transcription Factor RelA | 2015 |
Protective effect of δ-amyrone against ethanol-induced gastric ulcer in mice.
Topics: Animals; Cytokines; Disease Models, Animal; Ethanol; Gastric Acidity Determination; Gastric Mucosa; Immunohistochemistry; Male; Mice; Mucus; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Protective Agents; Stomach Ulcer; Transcription Factor RelA; Triterpenes | 2015 |
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology.
Topics: Activins; Adult; Animals; Body Weight; Cystic Fibrosis; Disease Models, Animal; Female; Follistatin; Humans; Inflammation Mediators; Lung; Macrophages; Male; Mice; Mice, Transgenic; Middle Aged; Mucus; Neutrophil Infiltration; Neutrophils; Pneumonia; Respiratory Function Tests; Respiratory Mucosa; Young Adult | 2015 |
The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Disease Models, Animal; Epithelial Cells; Female; Flavonoids; Gene Expression Regulation; Glycyrrhiza uralensis; Histone Deacetylase 2; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; STAT6 Transcription Factor | 2015 |
The sickle cell mouse lung: proinflammatory and primed for allergic inflammation.
Topics: Anemia, Sickle Cell; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Hemizygote; Hypersensitivity; Inflammation; Leukocyte Count; Lung; Mice, Inbred C57BL; Mucus; Ovalbumin; T-Lymphocytes | 2015 |
The anti-allergic activity of Cymbopogon citratus is mediated via inhibition of nuclear factor kappa B (Nf-Κb) activation.
Topics: Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cymbopogon; Cytokines; Disease Models, Animal; Eosinophil Peroxidase; Eosinophils; Hypersensitivity; Interleukin-4; Leukocytes; Lung; Male; Mice; Mites; Mucus; NF-kappa B; Phytotherapy; Plant Extracts; Signal Transduction | 2015 |
Carvedilol attenuates inflammatory biomarkers and oxidative stress in a rat model of ulcerative colitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Carbazoles; Carvedilol; Colitis, Ulcerative; Colon; Cytokines; Dinoprostone; Disease Models, Animal; DNA; Male; Malondialdehyde; Mucus; Nitric Oxide; Oxidative Stress; Propanolamines; Rats, Wistar; RNA; Sulfhydryl Compounds | 2015 |
Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response.
Topics: Adaptive Immunity; Animals; Asthma; Cell Death; Cell Line; Cell Survival; Dinoprost; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Environmental Exposure; Female; Mice, Inbred BALB C; Mucus; Oxidative Stress; Particulate Matter; Petroleum; Petroleum Pollution; Pneumonia; Superoxides; Time Factors | 2015 |
Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ+ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis.
Topics: Animals; Antimicrobial Cationic Peptides; Colitis; Cytokines; Disease Models, Animal; Intestinal Mucosa; Lymphopenia; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mucus; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Pattern Recognition; Signal Transduction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2015 |
SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model.
Topics: Acute Disease; Animals; Anthracenes; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Hypersensitivity; Immunoglobulin E; Inflammation; JNK Mitogen-Activated Protein Kinases; Lung; Mice, Inbred C57BL; Mucus; Ovalbumin; Phosphorylation; Toll-Like Receptor 9 | 2015 |
PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function.
Topics: Adoptive Transfer; Animals; Antigens, CD; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Eosinophilia; GATA3 Transcription Factor; Gene Knockout Techniques; Humans; Immunoglobulin E; Mice, Inbred C57BL; Mucus; Ovalbumin; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Spleen; T-Box Domain Proteins; Th1 Cells; Th2 Cells | 2015 |
Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allergens; Animals; Asthma; Case-Control Studies; Cell Line; Cytokines; Disease Models, Animal; Down-Regulation; Female; Gene Expression; Humans; Hypersensitivity; Male; Mice; Mucin 5AC; Mucus; NF-kappa B; Ovalbumin; Protein Kinase Inhibitors; Pyroglyphidae; Respiratory Mucosa; rho-Associated Kinases; Signal Transduction; STAT6 Transcription Factor | 2015 |
[Effects of ozone oxidative stress on the airway hyperresponsiveness and mucus production in mice with acute allergic airway inflammation].
Topics: Animals; Asthma; Bronchoalveolar Lavage; Disease Models, Animal; Female; Inflammation; Interleukin-13; Interleukin-17; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Oxidative Stress; Ozone; Respiratory Hypersensitivity; Respiratory System; Tumor Necrosis Factor-alpha | 2015 |
Callicarpa japonica Thunb. attenuates cigarette smoke-induced neutrophil inflammation and mucus secretion.
Topics: Animals; Bronchoalveolar Lavage Fluid; Callicarpa; Cell Line; Cell Line, Tumor; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Leukocyte Elastase; Lung; Male; Mice, Inbred C57BL; Mucus; Neutrophils; Nicotiana; Plant Extracts; Plant Leaves; Plant Stems; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Smoke; Tumor Necrosis Factor-alpha | 2015 |
Glucagon Like Peptide-1 (GLP-1) Modulates OVA-Induced Airway Inflammation and Mucus Secretion Involving a Protein Kinase A (PKA)-Dependent Nuclear Factor-κB (NF-κB) Signaling Pathway in Mice.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cyclic AMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; E-Selectin; Glucagon-Like Peptide 1; Inflammation Mediators; Leukocyte Count; Leukocytes; Mice; Mucus; NF-kappa B; Ovalbumin; Signal Transduction | 2015 |
Copper oxide nanoparticles aggravate airway inflammation and mucus production in asthmatic mice via MAPK signaling.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Copper; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Lung; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinases; Mucus; Nanoparticles; Ovalbumin; Phosphorylation; Reactive Oxygen Species; Respiratory Hypersensitivity | 2016 |
Resveratrol inhibits mucus overproduction and MUC5AC expression in a murine model of asthma.
Topics: Animals; Asthma; Cell Line; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Regulation; Humans; Lung; Mice, Inbred BALB C; Mucin 5AC; Mucus; Pneumonia; Resveratrol; Stilbenes | 2016 |
Continuous Exposure to Low-Dose-Rate Gamma Irradiation Reduces Airway Inflammation in Ovalbumin-Induced Asthma.
Topics: Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Choline; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Gamma Rays; Gene Expression; Humans; Immunoglobulin E; Interleukin-4; Interleukin-5; Lung; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin | 2015 |
On the Pathogenesis of Acute Exacerbations of Mucoobstructive Lung Diseases.
Topics: Animals; Disease Models, Animal; Disease Progression; Humans; Lung; Lung Diseases, Obstructive; Mice; Mucus | 2015 |
Heat-labile enterotoxin of Escherichia coli promotes intestinal colonization of Salmonella enterica.
Topics: Animals; Bacterial Load; Bacterial Toxins; Cell Line; Cell Survival; Diarrhea; Disease Models, Animal; Enterocytes; Enterotoxigenic Escherichia coli; Enterotoxins; Escherichia coli Proteins; Goblet Cells; Humans; Intestines; Jejunum; Mucins; Mucus; Salmonella Infections, Animal; Salmonella typhimurium; Swine | 2015 |
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion.
Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucins; Helicobacter pylori; KATP Channels; Male; Microbial Sensitivity Tests; Mucus; Prostaglandins; Protective Agents; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Thymol | 2016 |
Molecular Mechanisms of Airway Hyperresponsiveness in a Murine Model of Steroid-Resistant Airway Inflammation.
Topics: Adoptive Transfer; Animals; Asthma; Disease Models, Animal; Drug Resistance; Immunoblotting; Interleukin-13; Interleukin-17; Metaplasia; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, SCID; Mice, Transgenic; Mucus; Polymerase Chain Reaction; Respiratory Hypersensitivity; Th17 Cells; Th2 Cells; Transcriptome | 2016 |
Suhuang antitussive capsule at lower doses attenuates airway hyperresponsiveness, inflammation, and remodeling in a murine model of chronic asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflammation; Lamiaceae; Lung; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Plant Preparations | 2016 |
Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Dinoprostone; Disease Models, Animal; Gallic Acid; Gastric Mucosa; Magnoliopsida; Male; Malondialdehyde; Mucus; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Quercetin; Rats, Sprague-Dawley; Stomach; Stomach Ulcer | 2016 |
Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma.
Topics: Administration, Oral; Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Fallopia multiflora; Female; GATA3 Transcription Factor; Inflammation Mediators; Lung; Mice, Inbred BALB C; Mucus; Ovalbumin; Phytotherapy; Plant Extracts; Plant Roots | 2016 |
Alpha-boswellic acid protects against ethanol-induced gastric injury in rats: involvement of nuclear factor erythroid-2-related factor 2/heme oxygenase-1 pathway.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Biomarkers; Cytoprotection; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Juice; Gastric Mucosa; Heme Oxygenase (Decyclizing); Hydrogen-Ion Concentration; Lipid Peroxidation; Male; Mucus; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Stomach Ulcer; Triterpenes | 2016 |
Recombinant human deoxyribonuclease therapy improves airway resistance and reduces DNA extracellular traps in a murine acute asthma model.
Topics: Administration, Intranasal; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Deoxyribonucleases; Disease Models, Animal; DNA; Extracellular Traps; Female; Humans; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Recombinant Proteins | 2016 |
Early-Life Intranasal Colonization with Nontypeable Haemophilus influenzae Exacerbates Juvenile Airway Disease in Mice.
Topics: Animals; Bacterial Load; Cytokines; Disease Models, Animal; Disease Progression; Female; Haemophilus Infections; Haemophilus influenzae; Hypersensitivity; Mice; Mucin 5AC; Mucus; Nasal Mucosa; Reproductive Tract Infections | 2016 |
Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice.
Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Colitis, Ulcerative; Colon; Disease Models, Animal; Galactosyltransferases; Humans; Immunity, Mucosal; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; N-Acetylglucosaminyltransferases; Polysaccharides; Proteolysis | 2017 |
IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection.
Topics: Animals; Chronic Disease; Cystic Fibrosis; Disease Models, Animal; Interleukin-22; Interleukins; Lung; Mice; Mucus; Pneumonia; Protective Factors; Pseudomonas aeruginosa; Pseudomonas Infections | 2016 |
[The effect and injury to the airways of different sputum aspiration pressure in a rat model of mucus hypersecretion].
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Interleukin-1beta; Mucus; Pressure; Random Allocation; Rats; Respiratory System; Sputum; Tumor Necrosis Factor-alpha | 2016 |
The involvement of central nervous system histamine receptors in psychological stress-induced exacerbation of allergic airway inflammation in mice.
Topics: Animals; Antigens; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Central Nervous System; Cytokines; Disease Models, Animal; Disease Progression; Female; Histamine Antagonists; Immunoglobulin E; Mice; Mucus; Receptors, Histamine; Stress, Psychological | 2016 |
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Ericales; Ethanol; Female; Flavonoids; Gastrointestinal Motility; Glyburide; Histamine; Indomethacin; Male; Mice; Mucus; Naloxone; NG-Nitroarginine Methyl Ester; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Stomach Ulcer; Water; Yohimbine | 2017 |
IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models.
Topics: Allergens; Animals; Asthma; Blood Cells; Cytokines; Dermatophagoides pteronyssinus; Disease Models, Animal; Disease Progression; Gene Expression Regulation; I-kappa B Proteins; Inflammation Mediators; Mice; Mice, Knockout; Mucin 5AC; Mucus; Promoter Regions, Genetic; Protein Binding; Respiratory Hypersensitivity; Respiratory Mucosa | 2017 |
Laryngeal mucus hypersecretion is exacerbated after smoking cessation and ameliorated by glucocorticoid administration.
Topics: Animals; Cytokines; Disease Models, Animal; Glucocorticoids; Laryngeal Mucosa; Laryngitis; Male; Mucus; Rats, Sprague-Dawley; Smoking; Smoking Cessation; Triamcinolone | 2017 |
Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma.
Topics: Animals; Asthma; Biomarkers; Case-Control Studies; Cytokines; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Gene Knockdown Techniques; Humans; Interleukin-13; Male; Mice; Mice, Transgenic; Models, Biological; Mucin 5AC; Mucus; NF-kappa B; Ovalbumin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases | 2017 |
Anti-Helicobacter pylori and antiulcerogenic activity of Aframomum pruinosum seeds on indomethacin-induced gastric ulcer in rats.
Topics: Aluminum Hydroxide; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Gastric Mucosa; Helicobacter pylori; Indomethacin; Magnesium Hydroxide; Male; Methanol; Microbial Sensitivity Tests; Misoprostol; Mucus; Nitric Oxide; Phytotherapy; Plants, Medicinal; Rats, Sprague-Dawley; Seeds; Solvents; Stomach Ulcer; Time Factors; Zingiberaceae | 2017 |
Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.
Topics: Animals; Cytokines; Disease Models, Animal; Gene Expression; Humans; Mice; Mice, Knockout; Models, Biological; Mucin 5AC; Mucus; Ovalbumin; Promoter Regions, Genetic; Protein Binding; Respiratory Hypersensitivity; Respiratory Mucosa; Signal Transduction; src-Family Kinases; STAT6 Transcription Factor | 2017 |
Novel triple neurokinin receptor antagonist CS-003 inhibits respiratory disease models in guinea pigs.
Topics: Administration, Oral; Animals; Asthma; Bronchoconstriction; Capillary Permeability; Capsaicin; Cough; Cyclic S-Oxides; Disease Models, Animal; Guinea Pigs; Male; Morpholines; Mucus; Nicotiana; Ovalbumin; Pulmonary Disease, Chronic Obstructive; Receptors, Tachykinin; Respiratory Tract Diseases; Rhinitis; Smoke; Trachea | 2008 |
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration.
Topics: Animals; Arginase; Boronic Acids; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Activation; Female; Inflammation Mediators; Metaplasia; Mice; Mice, Inbred BALB C; Mucus; Nitrates; Nitric Oxide; Nitrosation; Proteins; Respiratory Hypersensitivity; Tyrosine; Up-Regulation | 2008 |
Endothelin A receptor antagonist modulates lymphocyte and eosinophil infiltration, hyperreactivity and mucus in murine asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Endothelin A Receptor Antagonists; Eosinophils; Lung; Lymphocyte Subsets; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Peptides, Cyclic | 2008 |
Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Eosinophilia; Female; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Interleukin-4; Interleukin-5; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Resveratrol; Stilbenes | 2009 |
Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma.
Topics: Airway Obstruction; Allergens; Animals; Apoptosis; Asthma; Cell Adhesion; Cytokines; Disease Models, Animal; Eosinophils; Gene Expression Profiling; Gene Expression Regulation; Immunization; Inhibitor of Apoptosis Proteins; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Microarray Analysis; Microtubule-Associated Proteins; Mucus; Ovalbumin; Repressor Proteins; Species Specificity; Survivin | 2009 |
Gastric antisecretory and antiulcer activities of Cyclea peltata (Lam.) Hook. f. & Thoms. in rats.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cyclea; Disease Models, Animal; Ethanol; Gastric Juice; Gastric Mucosa; Indomethacin; Male; Malondialdehyde; Mucus; Pepsin A; Peptic Ulcer; Phytotherapy; Plant Extracts; Plant Roots; Proteins; Rats; Rats, Wistar; Stomach; Sulfhydryl Compounds | 2009 |
Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen.
Topics: Adrenal Cortex Hormones; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Disease Models, Animal; Eosinophils; Female; Fibrosis; Mice; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Ovalbumin; Pneumonia; Tobacco Smoke Pollution; Transforming Growth Factor beta1 | 2009 |
Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice.
Topics: Adenosine; Allergens; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chronic Disease; Disease Models, Animal; Eosinophils; Gene Deletion; Gene Expression Regulation; Hypertrophy; Interleukin-4; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Myocytes, Smooth Muscle; Pneumonia; Receptor, Adenosine A2B; RNA, Messenger; Transforming Growth Factor beta | 2010 |
Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.
Topics: Animals; Asthma; Disease Models, Animal; Epithelial Cells; Gene Expression; Hepatocyte Nuclear Factor 3-beta; Hepatocyte Nuclear Factor 3-gamma; Lung; Mice; Mice, Transgenic; Mucus; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus.
Topics: Animals; Cell Line; Cervix Uteri; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillus; Mucus; Surface Properties; Vagina; Virion | 2009 |
Prostaglandin E2 receptor EP2, EP3, and EP4 agonists inhibit antigen-induced mucus hypersecretion in the nasal epithelium of sensitized rats.
Topics: Alprostadil; Animals; Dinoprostone; Disease Models, Animal; Hypertrophy; Male; Metaplasia; Methyl Ethers; Mucus; Nasal Mucosa; Neutrophil Infiltration; Rats; Rats, Inbred F344; Receptors, Prostaglandin E; Rhinitis | 2009 |
Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokine CCL5; Disease Models, Animal; Drug Evaluation, Preclinical; Eosinophil Peroxidase; Eosinophils; Immunoglobulin E; Interleukin-4; Interleukin-5; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Petasites; Phytotherapy; Plant Extracts; Th2 Cells | 2010 |
Gastroprotective activity of Trichosanthes cucumerina in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Ethanol; Female; Gastric Juice; Gastric Mucosa; Histamine Antagonists; Hydrogen-Ion Concentration; Indomethacin; Male; Mucus; Plant Components, Aerial; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Stomach Ulcer; Sucralfate; Trichosanthes | 2010 |
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates | 2010 |
The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice.
Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Eosinophils; Hypersensitivity; Immunoglobulin E; Inflammation; Inflammation Mediators; Isatis; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Phytotherapy; Plant Extracts; Plant Leaves | 2010 |
Pathology of gastrointestinal organs in a porcine model of cystic fibrosis.
Topics: Animals; Cell Proliferation; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Gallbladder; Gastrointestinal Tract; Inflammation; Intestines; Liver; Mucus; Muscle, Smooth; Organ Specificity; Pancreas; Sus scrofa | 2010 |
Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.
Topics: Alkylation; Animals; Anti-Ulcer Agents; Carbenoxolone; Cattle; Collagen; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Ethanol; Ethylmaleimide; Gastric Mucosa; Gastrins; Hydrolysis; Male; Milk Proteins; Mucus; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Swine; Whey Proteins | 2010 |
Lipids control mucus production in cystic fibrosis.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase IV; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Disease Models, Animal; Humans; Hypoglycemic Agents; Mice; Mice, Inbred CFTR; Mucus; PPAR gamma; Rosiglitazone; Thiazolidinediones | 2010 |
Gastrointestinal protective effect of dietary spices during ethanol-induced oxidant stress in experimental rats.
Topics: Alkaloids; Animals; Antioxidants; Benzodioxoles; Capsaicin; Capsicum; Catalase; Cytoprotection; Diet; Disease Models, Animal; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Gastrointestinal Diseases; Glutathione Reductase; Glutathione Transferase; Glycoproteins; Intestinal Mucosa; Male; Mucus; Oxidative Stress; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Wistar; Spices; Superoxide Dismutase; Zingiber officinale | 2010 |
Ozone increases airway hyperreactivity and mucus hyperproduction in mice previously exposed to allergen.
Topics: Air Pollutants; Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Interactions; Inhalation Exposure; Leukocyte Count; Leukocytes; Lung; Methacholine Chloride; Mice; Mucus; Ovalbumin; Ozone; Periodic Acid-Schiff Reaction; Respiratory Function Tests | 2010 |
Critical role of cytosolic phospholipase A2{alpha} in bronchial mucus hypersecretion in CFTR-deficient mice.
Topics: Animals; Arachidonic Acid; Bronchi; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Disease Models, Animal; Group IV Phospholipases A2; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Mucin 5AC; Mucus; Respiratory Mucosa; RNA, Small Interfering | 2010 |
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.
Topics: Animals; Animals, Newborn; Cystic Fibrosis; Disease Models, Animal; Ileus; Inflammation; Lung; Meconium; Mucus; Pancreatic Diseases; Radiography, Thoracic; Survival Analysis; Swine; Time Factors | 2010 |
Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro.
Topics: Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycyrrhizic Acid; Goblet Cells; Hyperplasia; Interleukin-4; Lipopolysaccharides; Lung Diseases, Obstructive; Male; Mice; Mice, Inbred ICR; Mucin 5AC; Mucus; Promoter Regions, Genetic; Transforming Growth Factor alpha | 2010 |
The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model.
Topics: Adoptive Transfer; Airway Remodeling; Animals; Antibodies, Monoclonal; Asthma; Blotting, Western; Cytokines; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Interleukin-17; Lung; Male; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Helper-Inducer; Tyrphostins | 2010 |
Antiulcer effects of Achyrocline satureoides (Lam.) DC (Asteraceae) (Marcela), a folk medicine plant, in different experimental models.
Topics: Achyrocline; Animals; Anti-Ulcer Agents; Brazil; Cimetidine; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Indomethacin; Medicine, Traditional; Mucus; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer | 2010 |
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.
Topics: Airway Remodeling; Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Epithelial Cells; Epithelium; Lung; Male; Mice; Mice, Inbred BALB C; Mucus; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrosation; Pneumonia; Simvastatin; Stress, Physiological | 2011 |
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer; Piperidines; Prostaglandins; Rats; Rats, Sprague-Dawley | 2010 |
Anti-asthmatic effect of Sanguisorba officinalis L. and potential role of heme oxygenase-1 in an ovalbumin-induced murine asthma model.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Heme Oxygenase-1; Histocytochemistry; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Mucus; Neutrophil Infiltration; Ovalbumin; Oxidative Stress; Plant Extracts; Plant Roots; Pulmonary Eosinophilia; Reactive Oxygen Species; Sanguisorba; Up-Regulation | 2010 |
Repeated stress reduces mucociliary clearance in animals with chronic allergic airway inflammation.
Topics: Adrenal Glands; Animals; Bronchial Hyperreactivity; Cilia; Disease Models, Animal; Epithalamus; Guinea Pigs; Hydrocortisone; Inflammation; Interleukin-3; Interleukin-4; Male; Mucociliary Clearance; Mucus; Organ Size; Ovalbumin; Stress, Psychological; Swimming | 2010 |
Exposing rodents to a combination of tobacco smoke and lipopolysaccharide results in an exaggerated inflammatory response in the lung.
Topics: Adrenal Cortex Hormones; Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Bronchoalveolar Lavage Fluid; Budesonide; Cyclopropanes; Disease Models, Animal; Inflammation Mediators; Lipopolysaccharides; Lung; Male; Mucus; Neutrophil Infiltration; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pneumonia; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Tobacco Smoke Pollution | 2010 |
Effects of astragaloside IV on IFN-gamma level and prolonged airway dysfunction in a murine model of chronic asthma.
Topics: Animals; Asthma; Astragalus Plant; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chronic Disease; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Female; Immune System; Inflammation; Interferon-gamma; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Phytotherapy; Plant Roots; Respiratory System; Saponins; Triterpenes | 2011 |
Effects of clarithromycin and dexamethasone on mucus production in isografted rat trachea.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Clarithromycin; Dexamethasone; Disease Models, Animal; Glucocorticoids; Goblet Cells; Lipopolysaccharides; Male; Metaplasia; Mucus; Rats; Rats, Inbred F344; Secretory Pathway; Severity of Illness Index; Trachea; Tracheitis; Transplantation, Isogeneic; Viscosity | 2011 |
Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Female; Genes, bcl-2; Humans; Hyperplasia; Lung; Male; Metaplasia; Mice; Mice, Inbred C57BL; Middle Aged; Mucous Membrane; Mucus; Reverse Transcriptase Polymerase Chain Reaction; Smoking | 2011 |
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; Cyclohexanols; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Epidermal Growth Factor; Ethanol; Eucalyptol; Gastric Mucosa; Hyptis; Male; Monoterpenes; Mucus; Oils, Volatile; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Stomach Ulcer | 2011 |
Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation.
Topics: Animals; Antigens, CD; Blotting, Western; Cell Adhesion Molecules; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Goblet Cells; Humans; Hypersensitivity; Immunohistochemistry; Lung; Male; Metaplasia; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mucus; Pneumonia; Spleen; T-Lymphocytes; Th2 Cells | 2011 |
Swine models of cystic fibrosis reveal male reproductive tract phenotype at birth.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anions; Chloride-Bicarbonate Antiporters; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epididymis; Male; Mucus; Phenotype; Swine; Vas Deferens | 2011 |
Indigofera suffruticosa Mill as new source of healing agent: involvement of prostaglandin and mucus and heat shock proteins.
Topics: Acetates; Animals; Anti-Ulcer Agents; Cytoprotection; Disease Models, Animal; Ethanol; Gastric Mucosa; HSP70 Heat-Shock Proteins; Immunohistochemistry; Indigofera; Male; Methanol; Mucus; Nitric Oxide; Plant Extracts; Proliferating Cell Nuclear Antigen; Prostaglandins; Rats; Solvents; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Water; Wound Healing | 2011 |
Blockade of human group X secreted phospholipase A2 (GX-sPLA2)-induced airway inflammation and hyperresponsiveness in a mouse asthma model by a selective GX-sPLA2 inhibitor.
Topics: Allergens; Animals; Asthma; Disease Models, Animal; Enzyme Inhibitors; Gene Knock-In Techniques; Group X Phospholipases A2; Humans; Inflammation; Mice; Mice, Knockout; Mucus | 2011 |
Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Butanols; Catalase; Convolvulaceae; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Free Radical Scavengers; Gastric Juice; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Lipid Peroxidation; Male; Mice; Mucus; Plant Extracts; Plant Leaves; Ranitidine; Rats; Rats, Sprague-Dawley; Solvents; Stomach Ulcer; Superoxide Dismutase | 2011 |
Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway.
Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Artemisinins; Artesunate; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Female; Gene Expression Regulation; Humans; Hypersensitivity; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyroglyphidae; Signal Transduction; Th2 Cells | 2011 |
IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Flow Cytometry; Granzymes; Humans; Hypersensitivity; Inflammation; Interferon-gamma; Interleukin-17; Interleukin-23; Lung Diseases; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucus; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Cytotoxic; Viral Load; Viral Proteins | 2011 |
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Female; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; KATP Channels; Male; Mice; Mucus; Nitric Oxide; Nitric Oxide Synthase; Plant Bark; Plant Extracts; Potassium Channel Blockers; Rats; Rats, Wistar; Reperfusion Injury; Stomach Ulcer; Stress, Physiological; Zanthoxylum | 2011 |
In vivo antiulcer activity of the aqueous extract of Bauhinia purpurea leaf.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Bauhinia; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Mucus; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Toxicity Tests, Acute | 2011 |
Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae).
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpenes; Ethanol; Gastric Acid; Hydrogen-Ion Concentration; Indomethacin; Marrubium; Mice; Mucus; Nitric Oxide; Phytotherapy; Plant Extracts; Plant Leaves; Stomach Ulcer | 2011 |
Environmental tobacco smoke and progesterone alter lung inflammation and mucous metaplasia in a mouse model of allergic airway disease.
Topics: Allergens; Animals; Asthma; Disease Models, Animal; Female; Humans; Hypersensitivity, Immediate; Male; Metaplasia; Mice; Mice, Inbred BALB C; Mucus; Pneumonia; Progesterone; Smoking; Tobacco Smoke Pollution | 2012 |
Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Goblet Cells; Hyperplasia; Inflammation; Injections, Intramuscular; Interferon-gamma; Male; Mice; Mice, Inbred BALB C; Mucus; Verapamil | 2012 |
Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity.
Topics: Administration, Oral; Analgesics; Animals; Chlorides; Chromosomes, Artificial, Bacterial; Colon; Disease Models, Animal; Enterochromaffin Cells; Gastrointestinal Agents; Gastrointestinal Motility; Goblet Cells; Green Fluorescent Proteins; Guinea Pigs; Humans; Hyperalgesia; Immunohistochemistry; Intestinal Mucosa; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mucus; Pain; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin 5-HT4 Receptor Agonists | 2012 |
Gastroprotective effect of Senecio candicans DC on experimental ulcer models.
Topics: Adenosine Triphosphatases; Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Biphenyl Compounds; Disease Models, Animal; Female; Flavonoids; Gastric Juice; Gastric Mucosa; India; Male; Mucus; Omeprazole; Picrates; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Senecio; Steroids; Stomach; Stomach Ulcer | 2012 |
Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Adhesion Molecules; Cell Count; Chemokines; Chitinases; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Flavonoids; Flavonols; Genes, Reporter; Inflammation; Inflammation Mediators; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; NF-kappa B; Nitric Oxide Synthase Type II; Ovalbumin; Protein Transport; Tumor Necrosis Factor-alpha | 2012 |
Gastroprotective activities of Turnera diffusa Willd. ex Schult. revisited: Role of arbutin.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Arbutin; Aspirin; Cell Line; Cytoprotection; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Immunologic Factors; Interleukin-10; Interleukin-6; Lipid Peroxidation; Liver; Male; Mucus; Nitric Oxide; Omeprazole; Phytotherapy; Plant Extracts; Plants, Medicinal; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Turnera | 2012 |
Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.
Topics: Airway Obstruction; Animals; Disease Models, Animal; Epithelial Sodium Channels; Lung Diseases, Obstructive; Mice; Mice, Inbred Strains; Mice, Transgenic; Mucus | 2012 |
Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation.
Topics: Animals; Bacterial Infections; Disease Models, Animal; Epithelial Sodium Channels; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mucus; Myeloid Differentiation Factor 88; Neutrophils; Pneumonia; Signal Transduction | 2012 |
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation.
Topics: Adoptive Transfer; Allergens; Animals; Asthma; Cytokines; Disease Models, Animal; Gene Expression Profiling; Immunity, Innate; Lung; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Mucus; Papain; Pulmonary Eosinophilia; T-Lymphocytes, Helper-Inducer; Th2 Cells | 2012 |
Microbiological and mucociliary properties of the ethanol extract of Hymenocardia acida on selected respiratory clinical isolates.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Bacteria; Cilia; Columbidae; Disease Models, Animal; Dose-Response Relationship, Drug; Expectorants; Magnoliopsida; Mice; Mice, Inbred Strains; Mucous Membrane; Mucus; Phytotherapy; Plant Extracts; Respiratory Tract Diseases; Trachea | 2011 |
Multiple peptidoglycan modification networks modulate Helicobacter pylori's cell shape, motility, and colonization potential.
Topics: Animals; Bacterial Physiological Phenomena; Bacterial Proteins; Cell Wall; Disease Models, Animal; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Mice; Mice, Inbred C57BL; Movement; Mucus; Mutation; Peptidoglycan | 2012 |
Components of Streptococcus pneumoniae suppress allergic airways disease and NKT cells by inducing regulatory T cells.
Topics: Adoptive Transfer; Animals; Asthma; Bacterial Capsules; Bacterial Proteins; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Mucus; Natural Killer T-Cells; Oligodeoxyribonucleotides; Streptococcus pneumoniae; Streptolysins; T-Lymphocytes, Regulatory; Th2 Cells | 2012 |
CD137 deficiency does not affect development of airway inflammation or respiratory tolerance induction in murine models.
Topics: Allergens; Animals; Asthma; Cytokines; Disease Models, Animal; Eosinophils; Humans; Immune Tolerance; Immunization; Immunoglobulin E; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Ovalbumin; Respiratory System; Th2 Cells; Tumor Necrosis Factor Receptor Superfamily, Member 9 | 2012 |
Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis.
Topics: Animals; Dextran Sulfate; Disease Models, Animal; Enterocolitis; Inflammation; Intestinal Mucosa; Intestines; Larva; Metagenome; Mice; Mucins; Mucus; Neutrophils; Phenotype; Tretinoin; Trinitrobenzenesulfonic Acid; Zebrafish | 2012 |
Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor.
Topics: Animals; Asthma; Chronic Disease; Disease Models, Animal; Female; Fluorobenzenes; GABA-A Receptor Antagonists; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Mice; Mice, Inbred BALB C; Mucus; Pyrimidines; Receptors, GABA-A; Rosuvastatin Calcium; Sulfonamides | 2012 |
Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: to establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease.
Topics: Animals; Bronchi; Disease Models, Animal; ErbB Receptors; Histone Deacetylase 2; Lipopolysaccharides; Male; Mucin 5AC; Mucus; Nicotiana; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Smoke; Toll-Like Receptor 4; Transcription Factor RelA | 2012 |
Gastroprotective activity of carvacrol on experimentally induced gastric lesions in rodents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Cymenes; Disease Models, Animal; Ethanol; Female; KATP Channels; Mice; Monoterpenes; Mucus; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Wistar; Reperfusion Injury; Stomach Ulcer | 2012 |
Effects and mechanism of arsenic trioxide on reversing the asthma pathologies including Th17-IL-17 axis in a mouse model.
Topics: Animals; Anti-Asthmatic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Calcium; Caspase 12; Cells, Cultured; Dexamethasone; Disease Models, Animal; Female; Interleukin-17; Lung; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Oxides; Signal Transduction; Th17 Cells | 2012 |
Antiulcerogenic effect of Croton urucurana Baillon bark.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Croton; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Indomethacin; Ligation; Male; Mucus; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Sulfhydryl Compounds | 2012 |
Comparative analysis of gastric bacterial microbiota in Mongolian gerbils after long-term infection with Helicobacter pylori.
Topics: Animals; Biodiversity; Disease Models, Animal; DNA Primers; Gastric Juice; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Mucus; Real-Time Polymerase Chain Reaction; RNA, Ribosomal, 16S; Stomach | 2012 |
Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma.
Topics: Anesthetics, Local; Animals; Asthma; Bronchi; Disease Models, Animal; Fibrosis; GATA3 Transcription Factor; Lidocaine; Lung; Male; Matrix Metalloproteinase 9; Mice; Mucus; Nebulizers and Vaporizers; T-Lymphocytes | 2012 |
In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states.
Topics: Adult; Allergens; Animals; Cations; Disease Models, Animal; Eosinophil Major Basic Protein; Eosinophils; Female; Humans; Inflammation; Ions; Leukocyte Count; Male; Mice; Mucus; Nasal Lavage; Olfactory Mucosa; Rhinitis; Sinusitis; Young Adult | 2012 |
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.
Topics: 3' Untranslated Regions; Airway Obstruction; Animals; Antiporters; Asthma; Bronchitis; Calcium; Child; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Cells; Genetic Predisposition to Disease; Humans; Interleukin-13; Ion Transport; Lung; Mice; Mice, Knockout; Mucus; Sulfate Transporters; Th2 Cells; Tracheitis | 2012 |
Antiulcer activity of the chloroform extract of Bauhinia purpurea leaf.
Topics: Animals; Anti-Ulcer Agents; Bauhinia; Chloroform; Chromatography, High Pressure Liquid; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Mucus; Omeprazole; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Solvents; Stomach Ulcer | 2012 |
Possible biochemical effects following inhibition of ethanol-induced gastric mucosa damage by Gymnema sylvestre in male Wistar albino rats.
Topics: Animals; Anti-Ulcer Agents; Cytoprotection; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gymnema sylvestre; Hydrogen-Ion Concentration; Male; Malondialdehyde; Mucus; Oxidative Stress; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; RNA; Stomach Ulcer; Sulfhydryl Compounds | 2012 |
Gastroprotective activity of the ethanolic extract and hexane phase of Combretum duarteanum Cambess. (Combretaceae).
Topics: Animals; Anti-Ulcer Agents; Combretum; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Gastric Mucosa; Hexanes; Male; Mice; Mucus; Nitric Oxide; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Signal Transduction; Solvents; Stomach Ulcer; Sulfhydryl Compounds | 2013 |
Gastroprotective mechanisms of the chloroform and ethyl acetate phases of Praxelis clematidea (Griseb.) R.M.King & H.Robinson (Asteraceae).
Topics: Acetates; Animals; Anti-Ulcer Agents; Asteraceae; Biomarkers; Chloroform; Cytoprotection; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Gastric Mucosa; Male; Mice; Mucus; Phytotherapy; Piroxicam; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Solvents; Stomach Ulcer | 2013 |
IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Goblet Cells; Humans; Interleukin-10; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mucus; Proteostasis Deficiencies | 2013 |
The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Inflammation; Isoquinolines; Lung; Male; Mast Cells; Mice; Mucus; Ovalbumin; Protein Kinase Inhibitors; Sulfonamides; Th2 Cells | 2012 |
Alleviating effects of Lactobacillus strains on pathogenic Vibrio parahaemolyticus-induced intestinal fluid accumulation in the mouse model.
Topics: Analysis of Variance; Animals; Bacterial Adhesion; Disease Models, Animal; Female; Histocytochemistry; Intestinal Mucosa; Intestinal Secretions; Intestines; Lactobacillus; Male; Mice; Mice, Inbred ICR; Mucus; Probiotics; Vibrio Infections; Vibrio parahaemolyticus | 2013 |
Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice.
Topics: Animals; Antigens, Dermatophagoides; Asthma; Complement Activation; Cytokines; Disease Models, Animal; Endothelial Cells; Eosinophils; Immunoglobulin E; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Mucus; Pneumonia; Pyroglyphidae; Respiratory Mucosa; Th1 Cells; Th2 Cells | 2013 |
A small molecule inhibitor of redox-regulated NF-kappa B and activator protein-1 transcription blocks allergic airway inflammation in a mouse asthma model.
Topics: Administration, Intranasal; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Eosinophils; Female; Humans; Inflammation; Interleukin-13; Lung; Mice; Mice, Inbred BALB C; Mucus; NF-kappa B; Ovalbumin; Oxidation-Reduction; Pyridazines; Thioredoxins; Transcription Factor AP-1; Triazoles; Tumor Cells, Cultured | 2002 |
Effect of polysaccharides from Angelica sinensis on gastric ulcer healing.
Topics: Angelica sinensis; Angiogenesis Inhibitors; Animals; Anti-Ulcer Agents; Disease Models, Animal; Drugs, Chinese Herbal; ErbB Receptors; Gastric Mucosa; Male; Mucus; Neovascularization, Pathologic; Ornithine Decarboxylase; Polysaccharides; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing | 2003 |
A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse.
Topics: Adoptive Transfer; Aerosols; Allergens; Animals; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; Disease Models, Animal; Eosinophils; Interleukin-5; Intubation, Intratracheal; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mucus; Ovalbumin; Pulmonary Eosinophilia; Respiratory Hypersensitivity; Respiratory Mucosa | 2003 |
CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction.
Topics: Animals; Bronchial Hyperreactivity; Bronchiolitis, Viral; Disease Models, Animal; Female; Goblet Cells; Humans; Immune Sera; Injections, Intraperitoneal; Macrophages, Alveolar; Metaplasia; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucus; Neutrophil Infiltration; Receptors, Interleukin-8B; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human | 2003 |
Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation.
Topics: Acute Disease; Animals; Capsaicin; Cytoplasmic Granules; Disease Models, Animal; Edema; Goblet Cells; Mucus; Rats; Rats, Sprague-Dawley; Recovery of Function; Remission, Spontaneous; Trachea; Tracheitis | 2003 |
In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Carcinoma, Mucoepidermoid; Cell Line, Tumor; Clarithromycin; Disease Models, Animal; Goblet Cells; Humans; In Vitro Techniques; Josamycin; Male; Mucus; Nasal Mucosa; Nose Neoplasms; Penicillins; Rats; Rats, Inbred F344; Respiratory Hypersensitivity; Secretory Rate | 2003 |
[Effect of azithromycin on mucus secretion from nasal epithelium].
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Cells, Cultured; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Mucus; Nasal Mucosa; Rats; Rats, Inbred F344; Rhinitis, Allergic, Perennial | 2003 |
A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma.
Topics: Animals; Asthma; Bronchi; Bronchial Provocation Tests; Cytoplasmic Granules; Disease Models, Animal; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mucins; Mucus; Myristoylated Alanine-Rich C Kinase Substrate; Ovalbumin; Peptide Fragments; Peptides; Proteins; Respiratory Mucosa | 2004 |
Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Bethanechol; Cimetidine; Disease Models, Animal; Eriocaulaceae; Ethanol; Gastric Juice; Gastrointestinal Contents; Hydrogen-Ion Concentration; Indomethacin; Lansoprazole; Male; Mice; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological | 2004 |
Complex role of the IL-4 receptor alpha in a murine model of airway inflammation: expression of the IL-4 receptor alpha on nonlymphoid cells of bone marrow origin contributes to severity of inflammation.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophilia; Goblet Cells; Hyperplasia; Lung; Metaplasia; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Transgenic; Mucus; Protein Subunits; Radiation Chimera; Receptors, Interleukin-4; Respiratory Hypersensitivity; Severity of Illness Index; Th2 Cells | 2004 |
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channels; Epithelium; Humans; Lung; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Mucus; Sodium; Sodium Channels | 2004 |
Breath condensate hydrogen peroxide correlates with both airway cytology and epithelial lining fluid ascorbic acid concentration in the horse.
Topics: Airway Obstruction; Animals; Ascorbic Acid; Breath Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Dehydroascorbic Acid; Diagnosis, Differential; Disease Models, Animal; Glutathione; Horses; Hydrogen Peroxide; Inflammation; Mucus; Neutrophils; Respiratory Mucosa; Respiratory System; Spectrophotometry | 2004 |
Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Butadienes; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Eosinophils; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Mucus; Nitriles; Ovalbumin; Phosphorylation; Vascular Cell Adhesion Molecule-1 | 2004 |
Expiratory chest compression for atelectasis: No harm, no foul-oops!
Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Disease Models, Animal; Intubation, Intratracheal; Mucus; Oxygen; Physical Therapy Modalities; Pulmonary Atelectasis; Pulmonary Gas Exchange; Pulmonary Ventilation; Rabbits; Random Allocation; Respiration; Respiration, Artificial; Ribs; Suction | 2004 |
Effects of expiratory rib cage compression combined with endotracheal suctioning on gas exchange in mechanically ventilated rabbits with induced atelectasis.
Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Disease Models, Animal; Female; Intubation, Intratracheal; Mucus; Oxygen; Physical Therapy Modalities; Pulmonary Atelectasis; Pulmonary Gas Exchange; Pulmonary Ventilation; Rabbits; Random Allocation; Respiration; Respiration, Artificial; Ribs; Suction | 2004 |
Reduced expression of transforming growth factor beta 1 exacerbates pathology in an experimental asthma model.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Female; Heterozygote; Immunization; Immunoglobulins; Inflammation; Interferon-gamma; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Ovalbumin; Respiratory Hypersensitivity; Th2 Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.
Topics: Animals; Bacterial Adhesion; Dextran Sulfate; Disease Models, Animal; Feces; Inflammatory Bowel Diseases; Lactobacillus; Mice; Mice, Inbred BALB C; Mucous Membrane; Mucus; Mutation; Probiotics | 2005 |
An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Chromones; Cytokines; Disease Models, Animal; Eosinophils; Lung; Male; Mice; Mice, Inbred BALB C; Morpholines; Mucus; Ovalbumin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Eosinophilia; Respiratory Hypersensitivity | 2005 |
[Effects of interleukin-13 on the gob-5 and MUC5AC expression in lungs of a murine asthmatic model].
Topics: Animals; Asthma; Chloride Channels; Disease Models, Animal; Immunohistochemistry; Interleukin-13; Male; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucins; Mucoproteins; Mucus; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
[The preventive effect of bacillus Calmette-Guerin vaccination in early life on airway inflammation and mucus production in a murine model of asthma].
Topics: Animals; Asthma; BCG Vaccine; Bronchi; Disease Models, Animal; Lung; Mice; Mice, Inbred C57BL; Mucins; Mucus; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vaccination | 2005 |
Allophylus serratus: a plant with potential anti-ulcerogenic activity.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Male; Mucus; Omeprazole; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Sapindaceae; Solvents; Stomach Ulcer | 2005 |
Menadione protects gastric mucosa against ethanol-induced ulcers.
Topics: Administration, Oral; Animals; Antifibrinolytic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Acid; Gastric Mucosa; Ligation; Male; Mucus; Peroxidase; Pylorus; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Vitamin K 3 | 2005 |
Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma.
Topics: Animals; Asthma; Cells, Cultured; Chloride Channels; Disease Models, Animal; Female; Gastrointestinal Tract; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucins; Mucoproteins; Mucus; Oligonucleotide Array Sequence Analysis; Respiratory Mucosa; RNA, Small Interfering | 2005 |
Differential effects of (S)- and (R)-enantiomers of albuterol in a mouse asthma model.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Apoptosis; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Female; Interleukin-13; Interleukin-4; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Stereoisomerism | 2005 |
Characteristic features of allergic airway inflammation in a murine model of infantile asthma.
Topics: Age Factors; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Goblet Cells; Immunoglobulin E; Inflammation; Lung; Metaplasia; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Th2 Cells | 2005 |
Antibody-antigen interaction in the airway drives early granulocyte recruitment through BLT1.
Topics: Animals; Antigen-Antibody Reactions; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemokines; Chemotaxis, Leukocyte; Disease Models, Animal; Granulocytes; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Lung; Male; Mice; Mice, Knockout; Mucus; Neutrophils; Ovalbumin; Receptors, Leukotriene B4; Receptors, Purinergic P2 | 2006 |
Cigarette smoke suppresses Th1 cytokine production and increases RSV expression in a neonatal model.
Topics: Animals; Animals, Newborn; Cytokines; Disease Models, Animal; Female; Inflammation Mediators; Interleukins; Lung; Mice; Mice, Inbred BALB C; Mucus; Nicotiana; Pneumonia; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Smoke; Th1 Cells; Uteroglobin; Viral Proteins | 2006 |
Culture of murine nasal epithelia: model for cystic fibrosis.
Topics: Animals; Cell Culture Techniques; Cell Differentiation; Cystic Fibrosis; Disease Models, Animal; Electrophysiology; Female; Male; Mice; Mucus; Nasal Mucosa; Sodium Channel Blockers | 2006 |
Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma.
Topics: Airway Obstruction; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Disease Models, Animal; Eosinophilia; Eosinophils; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin | 2005 |
Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma.
Topics: Animals; Antibodies, Monoclonal; Asthma; Cytokines; Disease Models, Animal; Female; Hepatitis A Virus Cellular Receptor 1; Inflammation; Interleukin-10; Membrane Proteins; Mice; Mice, Inbred BALB C; Mucus; Th2 Cells | 2005 |
Eradication of small intestinal bacterial overgrowth in the cystic fibrosis mouse reduces mucus accumulation.
Topics: Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Intestine, Small; Male; Metronidazole; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Mucins; Mucus; Periodic Acid-Schiff Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Mucus in chronic airway diseases: sorting out the sticky details.
Topics: Animals; Disease Models, Animal; Epithelial Cells; ErbB Receptors; Humans; Interleukin-13; Lung Diseases, Obstructive; Mice; Mucus; Respiratory Mucosa | 2006 |
Erratum: name change.
Topics: Animals; Asthma; Chloride Channels; Disease Models, Animal; Mice; Mucoproteins; Mucus; Respiratory Mucosa | 2006 |
A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Dendritic Cells; Disease Models, Animal; Immunity, Innate; Inflammation Mediators; Lung; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mucus; Ovalbumin; Receptor, Anaphylatoxin C5a; Signal Transduction; Th2 Cells | 2006 |
Contribution of IL-18-induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Embryo, Mammalian; Eosinophils; Fibroblasts; Goblet Cells; Humans; Immunity, Innate; Inflammation; Interleukin-18; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucus; Th1 Cells; Th2 Cells | 2006 |
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Female; Glucosides; Immunoglobulin E; Interleukin-13; Interleukin-4; Iridoid Glucosides; Iridoids; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Molecular Structure; Mucus; Ovalbumin; Plant Extracts; Pneumonia; Pulmonary Eosinophilia; Quinolines; Sulfides; Veronica | 2006 |
Gob-5 contributes to goblet cell hyperplasia and modulates pulmonary tissue inflammation.
Topics: Airway Resistance; Animals; Antigens; Bronchoalveolar Lavage Fluid; Chemokines; Chloride Channels; Disease Models, Animal; Epithelial Cells; Goblet Cells; Hyperplasia; Lipopolysaccharides; Mice; Mice, Knockout; Mucoproteins; Mucus; Ovalbumin; Pneumonia | 2006 |
The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model.
Topics: Acetates; Airway Obstruction; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Cyclopropanes; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Goblet Cells; Hyperplasia; Hypertrophy; Leukotriene Antagonists; Leukotrienes; Lung; Mice; Mice, Inbred BALB C; Mucus; Muscle, Smooth; Pulmonary Fibrosis; Quinolines; Receptors, Leukotriene; Respiratory Mucosa; Sulfides | 2006 |
Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.
Topics: Animals; Disease Models, Animal; Histocytochemistry; Lung; Lung Diseases, Obstructive; Metapneumovirus; Mice; Mice, Inbred BALB C; Mucus; Paramyxoviridae Infections; Periodic Acid-Schiff Reaction; Plethysmography, Whole Body; Pneumonia, Viral; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral | 2006 |
Death receptor-6 regulates the development of pulmonary eosinophilia and airway inflammation in a mouse model of asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Interferon-gamma; Mice; Mice, Knockout; Mucus; Ovalbumin; Pulmonary Eosinophilia; Receptors, Tumor Necrosis Factor; Th2 Cells | 2006 |
Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma.
Topics: Activins; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Follistatin; Immunization; Interleukins; Lung; Lymph Nodes; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Recombinant Proteins; Th2 Cells | 2006 |
The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease.
Topics: Acetylglucosaminidase; Administration, Inhalation; Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Chemokines, CXC; Cluster Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation; L-Lactate Dehydrogenase; Male; Mucus; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Respiratory Mechanics; RNA, Messenger; Species Specificity; Sulfur Dioxide; Time Factors; Tumor Necrosis Factor-alpha; Weight Loss | 2006 |
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Cell Movement; Chemokine CCL11; Chemokines, CC; Chronic Disease; Cytokines; Disease Models, Animal; Eosinophils; Gene Expression Profiling; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Inflammation; Ligands; Mast Cells; Mice; Mice, Knockout; Mucus; Receptors, CCR3; Receptors, Chemokine | 2006 |
[Effects of glucocorticoid on airway mucus secretion in asthma: experiment with asthmatic mouse model].
Topics: Aluminum Hydroxide; Animals; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Glucocorticoids; Immunohistochemistry; Injections, Intraperitoneal; Interleukin-4; Lung; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucins; Mucus; Ovalbumin; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models.
Topics: Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Central Nervous System Depressants; Dinoprostone; Disease Models, Animal; Ethanol; Flavonoids; Gastric Mucosa; Immersion; Indicators and Reagents; Indomethacin; Male; Mucus; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stomach Ulcer; Stress, Psychological; Treatment Outcome | 2007 |
A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Biological Availability; Bronchitis; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Line; Cell Membrane; Chemokines, CXC; Chemotaxis; Chemotaxis, Leukocyte; Cyclobutanes; Disease Models, Animal; Goblet Cells; Hyperplasia; Lipopolysaccharides; Lung; Macaca fascicularis; Male; Mice; Mice, Inbred BALB C; Mucins; Mucus; Neutrophils; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Vanadium Compounds | 2007 |
The tick salivary protein, Salp15, inhibits the development of experimental asthma.
Topics: Adjuvants, Immunologic; Animals; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; Disease Models, Animal; Female; Inflammation Mediators; Interleukin-13; Interleukin-4; Interleukin-5; Ixodes; Mice; Mice, Inbred BALB C; Mucus; Salivary Proteins and Peptides | 2007 |
Plasminogen is an important regulator in the pathogenesis of a murine model of asthma.
Topics: Animals; Antifibrinolytic Agents; Asthma; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Eosinophils; Gelatinases; Inflammation; Interleukin-5; Leukocytosis; Lung; Lymphocytes; Mice; Mice, Inbred C57BL; Mucus; Plasminogen; Tranexamic Acid; Tumor Necrosis Factor-alpha | 2007 |
Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestine.
Topics: Acetylcysteine; Animals; Bacteria; Body Weight; Cathartics; Cystic Fibrosis; Disease Models, Animal; Expectorants; Gastric Emptying; Gastrointestinal Transit; Gene Expression Regulation; Immunity, Innate; Inflammation; Intestine, Small; Mice; Mice, Inbred CFTR; Mucus; Polyethylene Glycols; RNA, Bacterial; RNA, Ribosomal, 16S | 2007 |
Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide.
Topics: Acute Disease; Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Interleukin-13; Interleukin-4; Mice; Mucus; Ovalbumin; Peptides; Pneumonia; Protein Binding; Recombinant Fusion Proteins; Respiratory Mucosa; Rhinitis, Allergic, Perennial; STAT6 Transcription Factor; Th2 Cells | 2007 |
Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model.
Topics: Administration, Oral; Animals; Asthma; Bronchial Hyperreactivity; Cultured Milk Products; Cytokines; Disease Models, Animal; Eosinophilia; Immunoglobulin E; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin | 2007 |
The involvement of type 1a angiotensin II receptors in the regulation of airway inflammation in a murine model of allergic asthma.
Topics: Animals; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Cell Count; Cell Differentiation; Cytokines; Disease Models, Animal; Immunoglobulin E; Lipopolysaccharides; Lung; Lymphocytes; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus; Neutrophils; Ovalbumin; Receptor, Angiotensin, Type 1 | 2007 |
Airway responses to esophageal acidification.
Topics: Airway Resistance; Animals; Bronchi; Cats; Disease Models, Animal; Esophagus; Female; Gastroesophageal Reflux; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Mucociliary Clearance; Mucus; Respiratory System | 2008 |
Glutamine preferentially inhibits T-helper type 2 cell-mediated airway inflammation and late airway hyperresponsiveness through the inhibition of cytosolic phospholipase A(2) activity in a murine asthma model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Cytokines; Disease Models, Animal; Eosinophils; Female; Glutamine; Mice; Mice, Inbred BALB C; Mucus; Neutrophils; Phospholipases A2, Cytosolic; Phosphorylation; Th2 Cells | 2008 |
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.
Topics: Animals; Colitis, Ulcerative; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Goblet Cells; Humans; Interleukin-22; Interleukins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucus; STAT3 Transcription Factor; Th2 Cells | 2008 |
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Topics: Animals; Antibody Formation; Bronchial Hyperreactivity; Chemokines; Chemotactic Factors; Dendritic Cells; Disease Models, Animal; Humans; Hypersensitivity; Immunity, Innate; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Mice; Mice, Transgenic; Mucus; Neutrophils; Picornaviridae Infections; Respiratory System; Rhinovirus; Th1 Cells; Th2 Cells; Ultraviolet Rays; Virus Inactivation; Virus Replication | 2008 |
EP4 agonist inhibits lipopolysaccharide-induced mucus secretion in airway epithelial cells.
Topics: Animals; Carcinoma, Mucoepidermoid; Cell Line, Tumor; Dinoprostone; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Goblet Cells; Lipopolysaccharides; Male; Mucus; Nasal Mucosa; Nose Neoplasms; Rats; Rats, Inbred F344; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Secretory Rate | 2008 |
Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.
Topics: Adenoviridae; Adenoviridae Infections; Airway Obstruction; Animals; Cell Culture Techniques; Cell Division; Disease Models, Animal; Interleukin-13; Male; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Respiratory Function Tests; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Post-allergen challenge inhibition of poly(ADP-ribose) polymerase harbors therapeutic potential for treatment of allergic airway inflammation.
Topics: Allergens; Animals; Cytokines; Disease Models, Animal; Inflammation; Isoquinolines; Lung; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Respiratory Hypersensitivity; Th2 Cells; Thiophenes; Treatment Outcome | 2008 |
Gastroprotective activity of Eriobotrya japonica seed extract on experimentally induced gastric lesions in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Eriobotrya; Gastric Acid; Gastric Juice; Gastric Mucosa; Gastrointestinal Agents; Male; Mucus; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Seeds; Stomach Ulcer | 2008 |
Successful prevalidation of the slug mucosal irritation test to assess the eye irritation potency of chemicals.
Topics: Animal Use Alternatives; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Eye; Irritants; L-Lactate Dehydrogenase; Mollusca; Mucus; Predictive Value of Tests; Reproducibility of Results; Skin; Toxicity Tests | 2008 |
Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease.
Topics: Aged; Animals; Asthma; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Epithelial Cells; Female; Genome, Human; Humans; Interleukin-13; Lung; Male; Membrane Transport Proteins; Mice; Middle Aged; Mucin 5AC; Mucins; Mucus; Neutrophil Infiltration; Neutrophils; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Sulfate Transporters; Th2 Cells | 2008 |
Mucous obstruction and airway hyperresponsiveness in mice.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Disease Models, Animal; Mice; Mucus; Plethysmography; Respiratory Function Tests | 2008 |
Symposium: Host defences.
Topics: Acquired Immunodeficiency Syndrome; Airway Resistance; Animals; Antigens; Cilia; Disease Models, Animal; Female; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Lung Diseases; Lung Neoplasms; Macrophages; Male; Mucus; Phagocytosis; Pulmonary Alveoli; Respiratory Hypersensitivity; Respiratory Tract Infections; Sheep | 1983 |
The chronically isoproterenol-treated rat in the study of cystic fibrosis: X-ray microanalysis of the submandibular gland.
Topics: Animals; Calcium; Cystic Fibrosis; Disease Models, Animal; Drug Interactions; Electron Probe Microanalysis; Female; Isoproterenol; Magnesium; Mucus; Potassium; Rats; Rats, Inbred Strains; Reserpine; Submandibular Gland | 1984 |
Hypersecretion of mucus glycoprotein by the gallbladder epithelium in experimental cholelithiasis.
Topics: Animals; Cholelithiasis; Cholestanol; Cholesterol; Cholic Acids; Disease Models, Animal; Epithelium; Female; Gallbladder; Glycoproteins; Guinea Pigs; Histocytochemistry; Lincomycin; Male; Mice; Mucus; Rabbits | 1981 |
Control and modulation of airway epithelial cells and their secretions.
Topics: Animals; Asthma; Bronchitis; Chronic Disease; Cystic Fibrosis; Disease Models, Animal; Dogs; Epithelial Cells; Humans; In Vitro Techniques; Mucus; Rats; Respiratory System; Sputum | 1983 |
Experimental chronic bronchitis.
Topics: Animals; Bronchi; Bronchitis; Chronic Disease; Cricetinae; Disease Models, Animal; Dogs; Epithelium; Glycoproteins; Guinea Pigs; Homeostasis; Humans; Lung Diseases; Mucus; Rabbits; Rats; Respiratory System | 1983 |
Effect of dexamethasone on antigen-induced high molecular weight glycoconjugate secretion in allergic guinea pigs.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Eosinophils; Glycoconjugates; Guinea Pigs; Hypersensitivity; Male; Molecular Weight; Mucus; Ovalbumin | 1995 |
Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells.
Topics: Aerosols; Animals; Disease Models, Animal; Epithelium; Glycoproteins; Hyperplasia; Hypertrophy; Lung; Lung Diseases, Obstructive; Male; Mucus; Rats; Rats, Sprague-Dawley; Research Design; Sulfites; Trachea | 1994 |
Antiulcerogenicity of the flavonoid fraction from Bidens aurea: comparison with ranitidine and omeprazole.
Topics: Acute Disease; Animals; Anti-Ulcer Agents; Cold Temperature; Disease Models, Animal; Female; Flavonoids; Gastric Mucosa; Glycoproteins; Male; Mucus; Omeprazole; Plant Extracts; Plants, Medicinal; Ranitidine; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer | 1994 |
Influence of simulated mucus on cough sounds in cats.
Topics: Animals; Cats; Cough; Disease Models, Animal; Female; Male; Mucus; Sound | 1993 |
MAO-A and -B inhibitors selectively alter Xenopus mucus-induced behaviors of snakes.
Topics: Analysis of Variance; Animals; Behavior, Animal; Clorgyline; Disease Models, Animal; Movement Disorders; Mucus; Selegiline; Snakes; Xenopus laevis | 1993 |
The effects of a cysteinyl leukotriene antagonist (ONO-1078) on antigen-induced responses in allergic sheep.
Topics: Airway Resistance; Animals; Antigens, Helminth; Ascaris; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chromones; Disease Models, Animal; Hypersensitivity; Mucus; Sheep; SRS-A | 1993 |
Keratinocyte growth factor ameliorates mucosal injury in an experimental model of colitis in rats.
Topics: Animals; Cell Division; Colitis; Disease Models, Animal; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Growth Substances; Intestinal Mucosa; Male; Mucins; Mucus; Necrosis; Peroxidase; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Ulcer | 1996 |
Evaluation of cecal ligation as a model of mucoid enteropathy in specific-pathogen-free rabbits.
Topics: Animals; Cecal Diseases; Cecum; Colon; Disease Models, Animal; Inflammation; Intestinal Diseases; Ligation; Mucus; Necrosis; Protein-Losing Enteropathies; Rabbits; Specific Pathogen-Free Organisms | 1996 |
The importance of leukotrienes in airway inflammation in a mouse model of asthma.
Topics: 5-Lipoxygenase-Activating Proteins; Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Carrier Proteins; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Membrane Proteins; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Pulmonary Eosinophilia; Respiratory Function Tests; Respiratory System | 1996 |
Cytoprotective activity in the gastric mucosa of rats exposed to carbon tetrachloride-induced liver injury.
Topics: Animals; Carbon Tetrachloride; Dinoprostone; Disease Models, Animal; Drug Resistance; Ethanol; Gastric Acid; Gastric Mucosa; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron, Scanning; Mucus; Rats; Rats, Wistar | 1997 |
Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Glycine; Hydrochloric Acid; Indomethacin; Male; Mucus; Pylorus; Rats; Rats, Wistar; Sodium Hydroxide; Solvents; Stomach Ulcer; Sulfhydryl Compounds | 1997 |
Early stages in the development of goblet cells in the paranasal sinuses: a multimethodological study in the rabbit.
Topics: Administration, Topical; Animals; Capsaicin; Cell Count; Cell Differentiation; Cytoplasmic Granules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Maxillary Sinusitis; Microscopy, Electron; Mucus; Nasal Mucosa; Rabbits; Secretory Rate | 1998 |
Inflammation and a thickened mucus layer in mice with cholesterol gallstones.
Topics: Animals; Cholecystitis; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Crystallization; Disease Models, Animal; Dogs; Inflammation; Interleukin-1; Mice; Mice, Inbred BALB C; Mucus; Peroxidase | 1998 |
Molecular pathophysiology of cystic fibrosis based on the rescued knockout mouse model.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Genes, Lethal; Genetic Therapy; Intestinal Diseases; Intestinal Mucosa; Intestines; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Mucus; Mutation; Phenotype; Receptors, Purinergic | 1998 |
Mucus transportability: the bovine trachea and frog palate models compared.
Topics: Animals; Anura; Cattle; Cystic Fibrosis; Disease Models, Animal; Humans; Mucociliary Clearance; Mucus; Palate; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sputum; Trachea | 1998 |
[Protective effects of teprenone and gefarnate against taurocholate/hydrochloric acid-induced acute gastric mucosal lesions in rats].
Topics: Acute Disease; Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Gastric Mucosa; Gastritis; Gefarnate; Hydrochloric Acid; Male; Mucus; Rats; Rats, Wistar; Taurocholic Acid | 1998 |
T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production.
Topics: Animals; Asthma; Disease Models, Animal; Eosinophilia; Flow Cytometry; Hypersensitivity; Inflammation; Interferon-gamma; Interleukins; Lung; Mice; Mice, Knockout; Mucus; Ovalbumin; Receptors, Interferon; T-Lymphocytes, Helper-Inducer; Th1 Cells; Th2 Cells | 1999 |
Soluble IL-4 receptor inhibits airway inflammation following allergen challenge in a mouse model of asthma.
Topics: Administration, Intranasal; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Models, Animal; Eosinophils; Female; Humans; Immunoglobulin E; Injections, Intraperitoneal; Leukocytes, Mononuclear; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Receptors, Interleukin-4; Solubility | 2000 |
Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Models, Animal; Eosinophils; Female; Humans; Interleukin-5; Lung; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Phospholipases A; Platelet Activating Factor; Recombinant Proteins | 2000 |
Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cell Division; Dexamethasone; Disease Models, Animal; Eosinophils; Epithelial Cells; Fibronectins; Immunoglobulin E; Interleukin-4; Interleukin-5; Leukocyte Count; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mucus; Ovalbumin; Plasma; Pulmonary Alveoli; Respiratory Mucosa; Species Specificity; Time Factors | 2000 |
Evaluation of the gastroprotective activity of cordatin, a diterpene isolated from Aparisthmium cordatum (Euphorbiaceae).
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Euphorbiaceae; Female; Gastric Acid; Gastric Juice; Gastric Mucosa; Lansoprazole; Male; Mice; Mucus; Omeprazole; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer; Trees | 2000 |
Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma.
Topics: Animals; Asthma; Cell Line; Chloride Channels; Cloning, Molecular; Disease Models, Animal; Epithelium; Gene Expression; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Mucoproteins; Mucus; Phenotype; Respiratory System; RNA, Antisense; RNA, Messenger; Transduction, Genetic; Transfection | 2001 |
Synergy of histone-derived peptides of coho salmon with lysozyme and flounder pleurocidin.
Topics: Aeromonas; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fish Diseases; Fish Proteins; Flounder; Gram-Negative Bacterial Infections; Histones; Mucus; Muramidase; Oncorhynchus kisutch; Peptides; Proteins; Vibrio; Vibrio Infections | 2001 |
Suppression of asthma-like responses in different mouse strains by oral tolerance.
Topics: Administration, Inhalation; Administration, Oral; Animals; Antibodies; Antigens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Drug Administration Schedule; Immune Tolerance; Immunoglobulin E; Immunoglobulin G; Immunosuppression Therapy; Interleukin-5; Mice; Mice, Inbred Strains; Mice, Transgenic; Mucus; Ovalbumin; Pulmonary Eosinophilia; Receptors, Antigen, T-Cell, gamma-delta; Th2 Cells | 2001 |
Sulfated polysaccharides, but not cellulose, increase colonic mucus in rats with loperamide-induced constipation.
Topics: Alginates; Animals; Carrageenan; Cellulose; Chondroitin Sulfates; Colon; Constipation; Dietary Fiber; Disease Models, Animal; Glucuronic Acid; Hexuronic Acids; Loperamide; Male; Mucus; Polysaccharides; Rats; Rats, Sprague-Dawley | 2001 |
Murine cytomegalovirus infection alters Th1/Th2 cytokine expression, decreases airway eosinophilia, and enhances mucus production in allergic airway disease.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Cytomegalovirus Infections; Disease Models, Animal; Eosinophilia; Female; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; RNA, Messenger; Th1 Cells; Th2 Cells | 2001 |
The CF salt controversy: in vivo observations and therapeutic approaches.
Topics: Aerosols; Amiloride; Animals; Cells, Cultured; Cystic Fibrosis; Disease Models, Animal; Diuretics; Goblet Cells; Humans; Ion Transport; Mice; Mice, Inbred C57BL; Microdialysis; Microscopy, Confocal; Mucus; Nasal Mucosa; Osmolar Concentration; Pulmonary Surfactants; Raffinose; Respiratory Mucosa; Sodium Chloride; Uridine Triphosphate | 2001 |
Exposure to diesel exhaust exacerbates allergen-induced airway responses in guinea pigs.
Topics: Allergens; Analysis of Variance; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Female; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; Inflammation; Inhalation Exposure; Leukocyte Count; Mucus; N-Acetylneuraminic Acid; Ovalbumin; Time Factors; Vehicle Emissions | 2001 |
In vivo microdialysis for determination of nasal liquid ion composition.
Topics: Animals; Chlorides; Cystic Fibrosis; Disease Models, Animal; Electrodes; Female; Ions; Male; Membrane Potentials; Mice; Mice, Inbred CFTR; Microdialysis; Mucus; Nasal Cavity; Nasal Mucosa; Osmolar Concentration; Perfusion; Potassium; Reproducibility of Results; Rheology; Sodium | 2002 |
Inflammatory responses and mucus secretion in rats with acute bronchiolitis induced by nickel chloride.
Topics: Animals; Bronchiolitis; Disease Models, Animal; Inflammation; Inhalation Exposure; Male; Mucus; Nickel; Particle Size; Rats; Rats, Wistar | 2002 |
Studies on the pathogenesis of diet-induced dog gallstones.
Topics: Amino Acids; Animals; Bile; Bile Pigments; Bilirubin; Cholelithiasis; Cholesterol, Dietary; Diet; Disease Models, Animal; Dogs; Female; Hydrogen-Ion Concentration; Male; Micelles; Mucus; Phospholipids; Proteins; Triglycerides | 1977 |
Modification of mucus in animal models of disease.
Topics: Animals; Bronchi; Disease Models, Animal; Epithelium; Glycoproteins; Hydrogen-Ion Concentration; Hypertrophy; Isoproterenol; Mucus; Nicotiana; Oxadiazoles; Plants, Toxic; Rats; Respiratory Tract Diseases; Smoke; Swine; Trachea | 1977 |
Animal models in clinical disease.
Topics: Animals; Cytoplasmic Granules; Disease Models, Animal; Exocrine Glands; Glycoproteins; Mucus; Rats; Respiratory Tract Diseases; Swine; Viscosity | 1978 |
The parasympathetic nervous system in airways disease.
Topics: Animals; Asthma; Bronchial Spasm; Disease Models, Animal; Dogs; Humans; Lung; Mucus; Parasympathetic Nervous System; Receptors, Cholinergic; Respiration; Vagus Nerve | 1979 |
An animal model for cystic fibrosis made by gene targeting.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Digestive System; Disease Models, Animal; Exocrine Glands; Gallbladder; Genitalia, Male; Genotype; Growth; Intestinal Obstruction; Liver; Male; Meconium; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mucus; Mutagenesis; Pancreas; RNA, Messenger; Salivary Glands | 1992 |
Experimental sinusitis in rabbits induced by aerobic and anaerobic bacteria: models for research in sinusitis.
Topics: Animals; Bacteroides fragilis; Bacteroides Infections; Blood Flow Velocity; Disease Models, Animal; Lactates; Lactic Acid; Microspheres; Mucus; Pneumococcal Infections; Rabbits; Serotyping; Sinusitis | 1991 |
The oral mucosa of the MRL/I mouse: a synoptic picture of systemic autoimmune disorders.
Topics: Animals; Autoimmune Diseases; Capillaries; Connective Tissue; Disease Models, Animal; Epithelium; Exocrine Glands; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Monocytes; Mouth Diseases; Mouth Mucosa; Mucus; Neutrophils; Thrombosis; Vasculitis | 1991 |
Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157:H7.
Topics: Animals; Bacterial Outer Membrane Proteins; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Intestine, Large; Intestine, Small; Kidney Tubular Necrosis, Acute; Male; Mice; Mucus; Plasmids; Species Specificity; Streptomycin; Virulence | 1990 |
A nasal allergy model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate.
Topics: Administration, Intranasal; Animals; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine; Male; Mucus; Nasal Mucosa; Passive Cutaneous Anaphylaxis; Rhinitis, Allergic, Perennial; Toluene 2,4-Diisocyanate | 1988 |
Common bile duct ligation in rabbit: a new model of acute cholecystitis description of histology and bile analysis.
Topics: Acute Disease; Animals; Bile; Bile Acids and Salts; Cholecystitis; Common Bile Duct; Disease Models, Animal; Gallbladder; Ligation; Male; Mucus; Phospholipids; Rabbits; Time Factors | 1988 |
Changes in glycoconjugates in rat submandibular gland after chronic treatment with reserpine and isoproterenol.
Topics: Animals; Cystic Fibrosis; Cytoplasmic Granules; Disease Models, Animal; Glycoconjugates; Isoproterenol; Male; Mucus; Rats; Rats, Inbred Strains; Reserpine; Submandibular Gland; Wheat Germ Agglutinins | 1988 |
Transition from normal to hypersecretory bronchial mucus in a canine model of bronchitis: changes in yield and composition.
Topics: Animals; Bronchi; Bronchitis; Disease Models, Animal; Dogs; Glycoproteins; Glycosaminoglycans; Mucus; Phospholipids; Sulfur Dioxide | 1988 |
Pharmacodynamic mechanism and therapeutic activity of ambroxol in animal experiments.
Topics: Albuterol; Ambroxol; Animals; Bromhexine; Cilia; Disease Models, Animal; Guinea Pigs; In Vitro Techniques; Male; Mucus; Pulmonary Surfactants; Trachea | 1987 |
Simian model for the evaluation of immunity to influenza.
Topics: Aerosols; Animals; Disease Models, Animal; Erythrocytes; Guinea Pigs; Haplorhini; Hemagglutination Inhibition Tests; Immunization, Secondary; Immunodiffusion; Immunoglobulin A; Macaca; Mucus; Nose; Orthomyxoviridae; Orthomyxoviridae Infections; Pharynx | 1974 |
Ingestion of asbestos.
Topics: Animals; Asbestos; Diet; Disease Models, Animal; Dogs; Guinea Pigs; Haplorhini; Mucus; Rabbits; Rats; Stomach; Stomach Ulcer | 1974 |
An interpretive summary of the Bermuda workshop.
Topics: Animals; Basement Membrane; Cell Division; Congresses as Topic; Disease Models, Animal; Environmental Exposure; Humans; Lung; Macrophages; Models, Biological; Mucus; Pulmonary Alveoli | 1970 |
Experimental chronic bronchitis. Pathology in the dog.
Topics: Air; Animals; Bronchi; Bronchitis; Chronic Disease; Cilia; Disease Models, Animal; Dogs; Environmental Exposure; Epithelial Cells; Histocytochemistry; Histological Techniques; Hyperplasia; Lung; Male; Microscopy, Electron; Mucus; Sulfur Dioxide; Time Factors | 1974 |
Evaluation of model systems for study of airway epithelium, cilia, and mucus.
Topics: Animals; Bronchi; Bronchitis; Cilia; Disease Models, Animal; Dogs; Epithelium; Glycoproteins; Haplorhini; Humans; Lung; Mice; Mitosis; Mucins; Mucous Membrane; Mucus; Nicotiana; Plants, Toxic; Rabbits; Rats; Smoking; Spirometry; Sputum; Sulfur Dioxide | 1970 |
Experimental requirements for the toxicological evaluation of tobacco smoke in the respiratory system.
Topics: Air Pollution; Animals; Cats; Cilia; Disease Models, Animal; Environmental Exposure; Humans; Macrophages; Methods; Mucus; Pharmaceutical Vehicles; Pulmonary Alveoli; Respiratory Physiological Phenomena; Smoking; Time Factors; Toxicology; Trachea | 1969 |
The canine tracheal pouch. A model for use in respiratory mucus research.
Topics: Animals; Disease Models, Animal; Dogs; Methods; Models, Biological; Mucus; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Radiography; Respiratory Tract Diseases; Trachea | 1970 |
Studies of lung defense to infections in inhalation toxicology.
Topics: Aerosols; Bacteria; Bacteriolysis; Cilia; Disease Models, Animal; Environmental Exposure; Epithelium; Gases; Infections; Lung; Lung Diseases; Macrophages; Models, Biological; Mouth; Mucous Membrane; Mucus; Nose; Phagocytosis; Pulmonary Alveoli; Time Factors | 1970 |
Integrated defense mechanisms in models of chronic pulmonary disease.
Topics: Aerosols; Animals; Antibodies; Bronchi; Chronic Disease; Cilia; Disease Models, Animal; Infections; Kidney; Lung; Lung Diseases; Macrophages; Mice; Models, Biological; Mucus; Phagocytosis; Phosphorus Isotopes; Proteus; Rats; Staphylococcus | 1970 |
Experimental bronchitis in animals due to sulphur dioxide and cigarette smoke. An automated quantitative study.
Topics: Animals; Bronchitis; Disease Models, Animal; Germ-Free Life; Lung; Methods; Models, Biological; Mucus; Nicotiana; Plants, Toxic; Rats; Sheep; Smoke; Species Specificity; Sulfur Dioxide; Time Factors; Tracheotomy | 1970 |