Page last updated: 2024-10-28

guaifenesin and Diarrhea

guaifenesin has been researched along with Diarrhea in 33 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
" All doses of the extract, its anti-motility fractions and loperamide individually stopped diarrhea within 6-24 h of administration, whilst significantly reducing mucus and fecal fluid content, urine production and intestinal bloating."7.78Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea. ( Balemba, OB; Boakye, PA; Brierley, SM; Pasilis, SP, 2012)
" All doses of the extract, its anti-motility fractions and loperamide individually stopped diarrhea within 6-24 h of administration, whilst significantly reducing mucus and fecal fluid content, urine production and intestinal bloating."3.78Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea. ( Balemba, OB; Boakye, PA; Brierley, SM; Pasilis, SP, 2012)
"• Patients completed the validated Prostate Cancer Symptom Indices questionnaire every 1-2 weeks, reporting urinary and bowel symptoms on a four- or five-point Likert scale."2.77Patient-reported quality of life during radiation treatment for localized prostate cancer: results from a prospective phase II trial. ( Chen, MH; Chen, RC; D'Amico, AV; Loffredo, M; McMahon, E; McPherson, CP; Nguyen, AU; Nguyen, PL; Zhang, Y, 2012)
"Diarrhea was seen after 16 hr, accompanying severe peritonitis."1.29Intestinal injuries caused by experimental palytoxicosis in mice. ( Ito, E; Ohkusu, M; Yasumoto, T, 1996)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199016 (48.48)18.7374
1990's5 (15.15)18.2507
2000's4 (12.12)29.6817
2010's6 (18.18)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Sauvaitre, T2
Durif, C2
Sivignon, A2
Chalancon, S2
Van de Wiele, T2
Etienne-Mesmin, L2
Blanquet-Diot, S2
Van Landuyt, J1
Roussel, C1
Uriot, O1
Van Herreweghen, F1
Yang, PJ1
LaMarca, M1
Kaminski, C1
Chu, DI1
Hu, DL1
Rubin, JE1
Costa, MO1
Hill, JE1
Kittrell, HE1
Fernando, C1
Huang, Y1
O'Connor, B1
Harding, JC1
Verbrugghe, E1
Van Parys, A1
Leyman, B1
Boyen, F1
Arnouts, S1
Lundberg, U1
Ducatelle, R1
Van den Broeck, W1
Yekta, MA1
Cox, E1
Haesebrouck, F1
Pasmans, F1
Nigg, C1
Naumann, UK1
Käser, L1
Vetter, W1
Swidsinski, A2
Loening-Baucke, V2
Verstraelen, H1
Osowska, S1
Doerffel, Y2
Kirsch, S1
Chen, RC1
Zhang, Y1
Chen, MH1
McMahon, E1
Loffredo, M1
McPherson, CP1
Nguyen, AU1
Nguyen, PL1
D'Amico, AV1
Boakye, PA1
Brierley, SM1
Pasilis, SP1
Balemba, OB1
ADAMS, JL1
Chiang, JM1
Changchien, CR1
Chen, JR1
Erlanson, P1
Lindqvist, B1
Lundh, G1
Breuer, NF1
Rampton, DS1
Tammar, A1
Murphy, GM1
Dowling, RH1
Poley, JR1
Patwari, AK1
Deb, M1
Dudeja, M1
Jayasheela, M1
Agarwal, A1
Singh, P1
Ito, E1
Ohkusu, M1
Yasumoto, T1
Dutta, P1
Mitra, U1
Saha, DR1
Niyogi, SK1
Manna, B1
Bhattacharya, SK1
Juntunen, M1
Kirjavainen, PV1
Ouwehand, AC1
Salminen, SJ1
Isolauri, E1
Kiselev, BS1
Dustukhamedov, NS1
Golubeva, IV1
Tashpulatov, RIu1
Bondarenko, VM1
Watson, WC1
Yagi, T2
Miyawaki, Y2
Nishikawa, A2
Yamauchi, K2
Kuwano, S2
Horiyama, S1
Kager, PA1
Farthing, MJ1
Ruiz de Aguiar Gonzalez, A1
Audibert Mena, L1
Welch, CE1
Teague, RH1
Fraser, D1
Clamp, JR1
Hinton, MH1
Giller, J1
Phillips, SF1
Paradny, R1
Kark, AE1
Farnik, J1
Kubicková, O1
Fencl, V1
Sullivan, MF1
Hulse, EV1
Mole, RH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Inflammaging Network: Bridging Low Grade Inflammation With Gut Microbiota and Intestinal Barrier Function in Elderly Humans[NCT01218165]Early Phase 148 participants (Anticipated)Interventional2010-05-31Completed
A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Active Pouchitis[NCT00583076]Phase 219 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for guaifenesin and Diarrhea

ArticleYear
Solitary rectal ulcer syndrome: an endoscopic and histological presentation and literature review.
    International journal of colorectal disease, 2006, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Biopsy; Colonoscopy; Constipation; Diagnostic Errors; Diarrhea; Female; Gastroint

2006
Receptors and recognition mechanisms in intestinal infection.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985, Volume: 79, Issue:5

    Topics: Age Factors; Animals; Bacterial Infections; Bacterial Physiological Phenomena; Binding Sites; Cattle

1985

Trials

3 trials available for guaifenesin and Diarrhea

ArticleYear
Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea.
    Gastroenterology, 2008, Volume: 135, Issue:2

    Topics: Administration, Oral; Adult; Aged; Bacteria; Bacteroides; Chronic Disease; Diarrhea; Eubacterium; Fe

2008
Patient-reported quality of life during radiation treatment for localized prostate cancer: results from a prospective phase II trial.
    BJU international, 2012, Volume: 110, Issue:11

    Topics: Abdominal Pain; Aged; Aged, 80 and over; Diarrhea; Humans; Male; Middle Aged; Mucus; Prospective Stu

2012
[Chloramphenicol in shigellosis. Experimental part].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1965, Volume: 198, Issue:4

    Topics: Antibodies; Chloramphenicol; Clinical Trials as Topic; Diarrhea; Drug Resistance, Microbial; Dysente

1965

Other Studies

28 other studies available for guaifenesin and Diarrhea

ArticleYear
    Nutrients, 2021, Sep-14, Volume: 13, Issue:9

    Topics: Cell Adhesion; Diarrhea; Dietary Fiber; Enterotoxigenic Escherichia coli; Enterotoxins; Escherichia

2021
Role of mucus-bacteria interactions in Enterotoxigenic Escherichia coli (ETEC) H10407 virulence and interplay with human microbiome.
    NPJ biofilms and microbiomes, 2022, 10-20, Volume: 8, Issue:1

    Topics: Bacteria; Caco-2 Cells; Diarrhea; Enterotoxigenic Escherichia coli; Escherichia coli Infections; Hum

2022
Hydrodynamics of defecation.
    Soft matter, 2017, Jul-26, Volume: 13, Issue:29

    Topics: Animals; Cats; Constipation; Defecation; Diarrhea; Feces; Hydrodynamics; Models, Biological; Mucus;

2017
Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with "Brachyspira hampsonii" strain 30446.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animal Husbandry; Animals; Brachyspira; Colitis; Colon; Diarrhea; Feces; Gastrointestinal Hemorrhage

2013
Heat-labile enterotoxin of Escherichia coli promotes intestinal colonization of Salmonella enterica.
    Comparative immunology, microbiology and infectious diseases, 2015, Volume: 43

    Topics: Animals; Bacterial Load; Bacterial Toxins; Cell Line; Cell Survival; Diarrhea; Disease Models, Anima

2015
[Ulcerative colitis. Main symptoms: bloody mucous diarrhea, tenesmus, abdominal pain].
    Praxis, 2008, Feb-20, Volume: 97, Issue:4

    Topics: Abdominal Pain; Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ul

2008
[Functional biostructure of colonic microbiota (central fermenting area, germinal stock area and separating mucus layer) in healthy subjects and patients with diarrhea treated with Saccharomyces boulardii].
    Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 1

    Topics: Adult; Case-Control Studies; Chronic Disease; Colon; Diarrhea; Feces; Female; Fermentation; Humans;

2010
Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea.
    Journal of ethnopharmacology, 2012, Jul-13, Volume: 142, Issue:2

    Topics: Animals; Antidiarrheals; Body Weight; Cecum; Colon; Diarrhea; Diet; Dietary Sucrose; Drinking; Feces

2012
THE COLON PATTERNS IN ANXIETY AND INTROSPECTION.
    The New Zealand medical journal, 1964, Volume: 63

    Topics: Anxiety; Colitis; Colonic Diseases; Colonic Diseases, Functional; Constipation; Defecation; Diarrhea

1964
Hypersecreting villous rectal papilloma leading to excessive electrolyte-fluid losses and acute renal failure.
    Acta medica Scandinavica, 1967, Volume: 182, Issue:1

    Topics: Acute Kidney Injury; Calcium; Chlorides; Colonic Neoplasms; Diarrhea; Humans; Male; Middle Aged; Muc

1967
Effect of colonic perfusion with sulfated and nonsulfated bile acids on mucosal structure and function in the rat.
    Gastroenterology, 1983, Volume: 84, Issue:5 Pt 1

    Topics: Animals; Bile Acids and Salts; Biological Transport; Chenodeoxycholic Acid; Cholic Acid; Cholic Acid

1983
Chronic nonspecific diarrhea in children: investigation of the surface morphology of small bowel mucosa utilizing the scanning electron microscope.
    Journal of pediatric gastroenterology and nutrition, 1983, Volume: 2, Issue:1

    Topics: Atrophy; Child; Child, Preschool; Chronic Disease; Cytoplasm; Diarrhea; Humans; Infant; Intestinal M

1983
Clinical and laboratory predictors of invasive diarrhoea in children less than five years old.
    Journal of diarrhoeal diseases research, 1993, Volume: 11, Issue:4

    Topics: Acute Disease; Child, Preschool; Diarrhea; Feces; Female; Humans; Infant; Male; Mucus; Occult Blood;

1993
Intestinal injuries caused by experimental palytoxicosis in mice.
    Toxicon : official journal of the International Society on Toxinology, 1996, Volume: 34, Issue:6

    Topics: Acrylamides; Animals; Cnidarian Venoms; Diarrhea; Edema; Epithelium; Injections, Intraperitoneal; In

1996
Mucoid presentation of acute enterocolitis in children: a hospital-based case-control study.
    Acta paediatrica (Oslo, Norway : 1992), 1999, Volume: 88, Issue:8

    Topics: Acute Disease; Analysis of Variance; Animals; Case-Control Studies; Child, Preschool; Diarrhea; Dyse

1999
Adherence of probiotic bacteria to human intestinal mucus in healthy infants and during rotavirus infection.
    Clinical and diagnostic laboratory immunology, 2001, Volume: 8, Issue:2

    Topics: Bacterial Adhesion; Bifidobacterium; Child, Preschool; Diarrhea; Feces; Humans; In Vitro Techniques;

2001
[Isolation of bacteria of the Klebsiella genus in diarrhea in polar researchers].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1978, Issue:12

    Topics: Cold Climate; Diarrhea; Enterobacter; Enterobacteriaceae; Feces; Humans; Klebsiella; Mucus; Pharynx;

1978
Symposium on diarrhea. 2. Clinical diagnosis of the causes of diarrhea.
    Canadian Medical Association journal, 1977, Apr-09, Volume: 116, Issue:7

    Topics: Acute Disease; Chronic Disease; Diarrhea; Feces; Humans; Infections; Medical History Taking; Melena;

1977
Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by indomethacin in rats.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Colon; Diarrhea; Dinoprostone; Electrolytes; Femal

1991
Prostaglandin E2-mediated stimulation of mucus synthesis and secretion by rhein anthrone, the active metabolite of sennosides A and B, in the mouse colon.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:8

    Topics: Animals; Anthracenes; Colon; Diarrhea; Dinoprostone; Female; Mice; Mucus

1990
[Amebic dysentery; diarrhea with blood and mucus urges to a study of the feces].
    Nederlands tijdschrift voor geneeskunde, 1989, Oct-14, Volume: 133, Issue:41

    Topics: Adult; Animals; Blood; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Feces; Humans; Male; Mucu

1989
[The irritable colon. A retrospective study of 217 cases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-20, Volume: 116, Issue:38

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Cicatrix; Colonic Diseases, Functional; Constip

1974
Cancer of the gastrointestinal tract. Late effects of gastrectomy.
    JAMA, 1974, Jun-03, Volume: 228, Issue:10

    Topics: Afferent Loop Syndrome; Anemia, Macrocytic; Diarrhea; Dumping Syndrome; Folic Acid Deficiency; Gastr

1974
Changes in monosaccharide content of mucous glycoproteins in ulcerative colitis.
    British medical journal, 1973, Jun-16, Volume: 2, Issue:5867

    Topics: Chromatography, Gas; Chronic Disease; Colitis, Ulcerative; Diarrhea; Fucose; Galactosamine; Galactos

1973
Salmonella dublin abortion in cattle.
    The Veterinary record, 1973, Aug-11, Volume: 93, Issue:6

    Topics: Abortion, Veterinary; Agglutination Tests; Animals; Cattle; Cattle Diseases; Diarrhea; Dysentery; Fe

1973
Electrolyte absorption and secretion in the human colon.
    The American journal of digestive diseases, 1972, Volume: 17, Issue:11

    Topics: Adult; Bicarbonates; Biological Transport, Active; Chlorides; Colon; Diarrhea; Humans; Intestinal Ab

1972
Adenomas of the colon.
    The American journal of gastroenterology, 1968, Volume: 50, Issue:3

    Topics: Adenoma; Adult; Aged; Carcinoma; Colonic Neoplasms; Diarrhea; Electrosurgery; Female; Gastrointestin

1968
The mucus-depleting action of bile in the small intestine of the irradiated rat.
    British journal of experimental pathology, 1965, Volume: 46, Issue:3

    Topics: Animals; Bile; Bile Acids and Salts; Diarrhea; Intestinal Absorption; Intestinal Mucosa; Intestine,

1965