Page last updated: 2024-10-28

guaifenesin and Dehydration

guaifenesin has been researched along with Dehydration in 16 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Dehydration: The condition that results from excessive loss of water from a living organism.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have shown a dehydration-induced depression of TTV which was reversed by rehydration."1.26Effect of iodide on mucociliary transport in anesthetized dogs. ( Carson, SA; Chopra, SK; Tashkin, DP, 1982)
"Internal dehydration produced progressively viscous mucus, severe acinar gaping with mucus anchored in the acini, a heavy surface sheet, and deceleration or arrest of mucociliary flow."1.25Experimentally induced changes in nasal mucous secretory systems and their effect on virus infection in chickens. I. Effect on mucosal mrphology and function. ( Bang, BG; Bang, FB, 1969)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's7 (43.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Verdolini, K1
Titze, IR1
Fennell, A1
Lin, VY1
Kaza, N1
Birket, SE1
Kim, H1
Edwards, LJ1
LaFontaine, J1
Liu, L1
Mazur, M1
Byzek, SA1
Hanes, J1
Tearney, GJ1
Raju, SV1
Rowe, SM1
Burgel, PR1
Garland, AL1
Walton, WG1
Coakley, RD1
Tan, CD1
Gilmore, RC1
Hobbs, CA1
Tripathy, A1
Clunes, LA1
Bencharit, S1
Stutts, MJ1
Betts, L1
Redinbo, MR1
Tarran, R2
Trojanek, JB1
Cobos-Correa, A1
Diemer, S1
Kormann, M1
Schubert, SC1
Zhou-Suckow, Z1
Agrawal, R1
Duerr, J1
Wagner, CJ1
Schatterny, J1
Hirtz, S1
Sommerburg, O1
Hartl, D1
Schultz, C1
Mall, MA2
Saini, Y1
Dang, H1
Livraghi-Butrico, A1
Kelly, EJ1
Jones, LC1
O'Neal, WK1
Boucher, RC3
Clunes, MT1
Worthington, EN1
Babonis, LS1
Womack, MC1
Evans, DH1
BANG, BG2
BANG, FB2
Carson, SA1
Chopra, SK1
Tashkin, DP1
Giordano, A1
Shih, CK1
Holsclaw, DS1
Khan, MA1
Litt, M1
Sheridan, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Physiological Responses During the Use of Interactive Video Game and the Cardiopulmonary Exercise Test in Cystic Fibrosis and Healthy Individuals[NCT03229213]55 participants (Actual)Observational2017-08-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for guaifenesin and Dehydration

ArticleYear
Unplugging Mucus in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
    Annals of the American Thoracic Society, 2016, Volume: 13 Suppl 2

    Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dehydration; Epitheli

2016
Evidence for airway surface dehydration as the initiating event in CF airway disease.
    Journal of internal medicine, 2007, Volume: 261, Issue:1

    Topics: Aerosols; Animals; Cystic Fibrosis; Dehydration; Humans; Mice; Mice, Transgenic; Models, Animal; Muc

2007

Trials

1 trial available for guaifenesin and Dehydration

ArticleYear
Dependence of phonatory effort on hydration level.
    Journal of speech and hearing research, 1994, Volume: 37, Issue:5

    Topics: Adult; Brompheniramine; Dehydration; Double-Blind Method; Drug Combinations; Female; Guaifenesin; Hi

1994

Other Studies

13 other studies available for guaifenesin and Dehydration

ArticleYear
Excess mucus viscosity and airway dehydration impact COPD airway clearance.
    The European respiratory journal, 2020, Volume: 55, Issue:1

    Topics: Adult; Dehydration; Humans; Mucociliary Clearance; Mucus; Pulmonary Disease, Chronic Obstructive; Sm

2020
Airway mucus accumulation in COPD: the cholinergic paradox!
    The European respiratory journal, 2020, Volume: 55, Issue:1

    Topics: Cholinergic Agents; Dehydration; Humans; Mucus; Pulmonary Disease, Chronic Obstructive; Viscosity

2020
Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-01, Volume: 110, Issue:40

    Topics: Adult; Analysis of Variance; Cells, Cultured; Crystallization; Cystic Fibrosis; Dehydration; Epithel

2013
Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.
    American journal of respiratory cell and molecular biology, 2014, Volume: 51, Issue:5

    Topics: Airway Obstruction; Animals; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Dehydration; Genomics; M

2014
Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration.
    BMC genomics, 2014, Sep-10, Volume: 15

    Topics: Animals; Dehydration; Down-Regulation; Epithelial Sodium Channels; Gene Expression Profiling; Humans

2014
Introduction to section I: overview of approaches to study cystic fibrosis pathophysiology.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 742

    Topics: Airway Remodeling; Animals; Bacterial Infections; Biofilms; Biological Transport; Cystic Fibrosis; C

2011
Methods for ASL measurements and mucus transport rates in cell cultures.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 742

    Topics: Cells, Cultured; Dehydration; Fluorocarbons; Glycocalyx; Humans; Microscopy, Confocal; Microscopy, F

2011
Morphology and putative function of the colon and cloaca of marine and freshwater snakes.
    Journal of morphology, 2012, Volume: 273, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Aquaporin 3; Cloaca; Colon; Dehydration; Enterobacter; Fresh Wat

2012
Effect of water deprivation on nasal mucous flow.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1961, Volume: 106

    Topics: Birds; Dehydration; Mucous Membrane; Mucus; Nose; Respiratory Physiological Phenomena; Respiratory S

1961
Effect of iodide on mucociliary transport in anesthetized dogs.
    European journal of respiratory diseases, 1982, Volume: 63, Issue:4

    Topics: Anesthesia, Intravenous; Animals; Cilia; Dehydration; Dogs; Injections, Intravenous; Iodides; Mucus;

1982
Mucus clearance: in vivo canine tracheal vs. in vitro bullfrog palate studies.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 42, Issue:5

    Topics: Animals; Anura; Atropine; Biological Transport; Cilia; Dehydration; Dogs; Female; Mucus; Palate; Ran

1977
Obstructions of the intestinal tract.
    The Nursing clinics of North America, 1975, Volume: 10, Issue:1

    Topics: Anxiety; Auscultation; Blood Volume; Dehydration; Gastric Juice; Gastric Mucosa; Humans; Intestinal

1975
Experimentally induced changes in nasal mucous secretory systems and their effect on virus infection in chickens. I. Effect on mucosal mrphology and function.
    The Journal of experimental medicine, 1969, Jul-01, Volume: 130, Issue:1

    Topics: Amino Alcohols; Animals; Chickens; Cilia; Cocaine; Cold Temperature; Dehydration; Ethers; Germ-Free

1969