Page last updated: 2024-10-28

guaifenesin and Colorectal Neoplasms

guaifenesin has been researched along with Colorectal Neoplasms in 27 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"Chemotherapeutic drugs for colorectal cancer(CRC) which is currently the third most lethal cancer globally, are administered intravenously (iv) due to their low oral bioavailability resulting from their physicochemical properties."5.56Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization. ( Aktaş, Y; Benito, JM; Bilensoy, E; Ünal, S, 2020)
" In addition, we evaluated the separate and combined effects of PNA and epidermal growth factor (EGF) on cell proliferation in human HT29 colorectal cancer cells, by using tritiated thymidine incorporation and cell counts."3.68Peanut lectin: a mitogen for normal human colonic epithelium and human HT29 colorectal cancer cells. ( Rhodes, JM; Ryder, SD; Smith, JA, 1992)
"Faecal tests are widely applied for colorectal cancer (CRC) screening and considered for triaging symptomatic patients with suspected CRC."1.56Biomarker measurement in non-invasively sampled colorectal mucus as a novel approach to colorectal cancer detection: screening and triage implications. ( Allison, J; Bandaletova, T; Francis, N; Loktionov, A; Mathur, J; Poullis, A; Soubieres, A; Sturt, J, 2020)
"Chemotherapeutic drugs for colorectal cancer(CRC) which is currently the third most lethal cancer globally, are administered intravenously (iv) due to their low oral bioavailability resulting from their physicochemical properties."1.56Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization. ( Aktaş, Y; Benito, JM; Bilensoy, E; Ünal, S, 2020)
"Noninvasive colorectal cancer detection and screening remain global diagnostic challenges because the existing stool tests either lack sensitivity or are complex and expensive."1.51Colorectal cancer detection by biomarker quantification in noninvasively collected colorectal mucus: preliminary comparison of 24 protein biomarkers. ( Bandaletova, T; Loktionov, A; Mathur, J; Poullis, A; Soubieres, A, 2019)
"The deleted in colorectal cancer (DCC) gene was initially described as a colon cancer-associated tumor suppressor gene and subsequently proposed to be involved in goblet cell differentiation, but its precise role in normal intestine physiology and in cancer remains to be established."1.30In vitro analysis of the role of DCC in mucus-secreting intestinal differentiation. ( Fabre, M; Martin, M; Real, FX; Ulloa, F, 1999)
"Early diagnosis of colorectal cancer may be delayed by the wide prevalence of gastrointestinal symptoms in the general population."1.29Comparison of gastrointestinal symptoms in colorectal carcinoma patients and community controls with respect to age. ( Curless, R; French, J; James, OF; Williams, GV, 1994)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (29.63)18.2507
2000's1 (3.70)29.6817
2010's9 (33.33)24.3611
2020's9 (33.33)2.80

Authors

AuthorsStudies
Nooredinvand, HA1
Poullis, A3
Wang, ZH1
Chu, M1
Yin, N1
Huang, W1
Liu, W1
Zhang, Z1
Liu, J1
Shi, J1
Loktionov, A3
Tajima, Y1
Okuda, S1
Hanai, T1
Hiro, J1
Masumori, K1
Koide, Y1
Kamiya, T1
Cheong, Y1
Inaguma, G1
Shimada, Y1
Wakai, T1
Takihara, H1
Akimoto, S1
Matsuoka, H1
Uyama, I1
Suda, K1
Soubieres, A2
Bandaletova, T2
Mathur, J2
Nallala, J1
Jeynes, C1
Saunders, S1
Smart, N1
Lloyd, G1
Riley, L1
Salmon, D1
Stone, N1
Francis, N1
Allison, J1
Sturt, J1
Ünal, S1
Aktaş, Y1
Benito, JM1
Bilensoy, E1
Zimmer, V2
Kreissler-Haag, D1
Hübschen, U1
Mues, EP1
Eltze, E1
Hecht, AL1
Casterline, BW1
Choi, VM1
Bubeck Wardenburg, J1
Lamendella, R1
Stewart, DB1
van Praagh, JB1
de Goffau, MC1
Harmsen, HJM1
Havenga, K1
Hardy, H1
Harris, J1
Lyon, E1
Beal, J1
Foey, AD1
Toden, S1
Lockett, TJ1
Topping, DL1
Scherer, BL1
Watson, EJ1
Southwood, JG1
Clarke, JM1
De Arcangelis, A1
Hamade, H1
Alpy, F1
Normand, S1
Bruyère, E1
Lefebvre, O1
Méchine-Neuville, A1
Siebert, S1
Pfister, V1
Lepage, P1
Laquerriere, P1
Dembele, D1
Delanoye-Crespin, A1
Rodius, S1
Robine, S1
Kedinger, M1
Van Seuningen, I1
Simon-Assmann, P1
Chamaillard, M1
Labouesse, M1
Georges-Labouesse, E1
White, V1
Scarpini, C1
Barbosa-Morais, NL1
Ikelle, E1
Carter, S1
Laskey, RA1
Miller, R1
Coleman, N1
Adelstein, BA1
Irwig, L1
Macaskill, P1
Turner, RM1
Chan, SF1
Katelaris, PH1
Boleij, A1
Tjalsma, H1
Roberton, AM1
Curless, R1
French, J1
Williams, GV1
James, OF1
Zhou, DY1
Feng, FC1
Zhang, YL1
Lai, ZS1
Zhang, WD1
Li, LB1
Xu, GL1
Wan, TM1
Pan, DS1
Zhou, D1
Kellokumpu, IH1
Andersson, LC1
Kellokumpu, SJ1
Fabre, M1
Martin, M1
Ulloa, F1
Real, FX1
Ryder, SD1
Smith, JA1
Rhodes, JM1
Sakamoto, K1
Nakano, G1
Nagamachi, Y1
Corfield, AP1
Clamp, JR1
Casey, AD1
Paraskeva, C1

Reviews

5 reviews available for guaifenesin and Colorectal Neoplasms

ArticleYear
Emerging role of colorectal mucus in gastroenterology diagnostics.
    World journal of gastroenterology, 2022, Mar-28, Volume: 28, Issue:12

    Topics: Biomarkers; Colonoscopy; Colorectal Neoplasms; Feces; Gastroenterology; Humans; Inflammatory Bowel D

2022
Colon mucus in colorectal neoplasia and beyond.
    World journal of gastroenterology, 2022, Aug-28, Volume: 28, Issue:32

    Topics: Animals; Colon; Colorectal Neoplasms; Dietary Fiber; Humans; Intestinal Mucosa; Mammals; Mucins; Muc

2022
Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology.
    Nutrients, 2013, May-29, Volume: 5, Issue:6

    Topics: Animals; Antimicrobial Cationic Peptides; Bacteria; Colorectal Neoplasms; Dietary Fiber; Epithelial

2013
Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer.
    Biological reviews of the Cambridge Philosophical Society, 2012, Volume: 87, Issue:3

    Topics: Colorectal Neoplasms; Diet; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Mucus

2012
Roles of endogenous substances and bacteria in colorectal cancer.
    Mutation research, 1993, Volume: 290, Issue:1

    Topics: Animals; Bacteria; Bile Acids and Salts; Colon; Colorectal Neoplasms; Humans; Mucus

1993

Other Studies

22 other studies available for guaifenesin and Colorectal Neoplasms

ArticleYear
Biological chemotaxis-guided self-thermophoretic nanoplatform augments colorectal cancer therapy through autonomous mucus penetration.
    Science advances, 2022, Volume: 8, Issue:26

    Topics: Animals; Chemotaxis; Colorectal Neoplasms; Drug Delivery Systems; Mice; Mucus; Nanoparticles; Silico

2022
Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients.
    Scientific reports, 2022, 10-28, Volume: 12, Issue:1

    Topics: Bacteria; Colon; Colorectal Neoplasms; Humans; Intestinal Mucosa; Microbiota; Mucus; RNA, Ribosomal,

2022
Colorectal cancer detection by biomarker quantification in noninvasively collected colorectal mucus: preliminary comparison of 24 protein biomarkers.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Case-Control St

2019
Characterization of colorectal mucus using infrared spectroscopy: a potential target for bowel cancer screening and diagnosis.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:8

    Topics: Cluster Analysis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Discriminant Analysis; Early Detec

2020
Biomarker measurement in non-invasively sampled colorectal mucus as a novel approach to colorectal cancer detection: screening and triage implications.
    British journal of cancer, 2020, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Biomarkers, Tumor; Colon; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay

2020
Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization.
    International journal of pharmaceutics, 2020, Jun-30, Volume: 584

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Camptothecin;

2020
The cecal mucus sign underlying appendiceal sessile serrated polyp/adenoma without dysplasia.
    Techniques in coloproctology, 2020, Volume: 24, Issue:12

    Topics: Adenoma; Colonic Polyps; Colorectal Neoplasms; Humans; Hyperplasia; Mucus

2020
Beware of cecal mucus: Interval appendix rest sessile serrated adenoma/polyp (SSA/P) without dysplasia.
    Gastroenterologia y hepatologia, 2022, Volume: 45, Issue:8

    Topics: Adenoma; Appendix; Colonic Polyps; Colorectal Neoplasms; Humans; Mucus

2022
A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease.
    Cell host & microbe, 2017, Oct-11, Volume: 22, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Bacteroides fragilis; Colorect

2017
Comment on "Mucus Microbiome of Anastomotic Tissue During Surgery Has Predictive Value for Colorectal Anastomotic Leakage".
    Annals of surgery, 2019, Volume: 269, Issue:5

    Topics: Anastomosis, Surgical; Anastomotic Leak; Colorectal Neoplasms; Humans; Microbiota; Mucus

2019
Response to Comment on "Mucus Microbiome of Anastomotic Tissue During Surgery Has Predictive Value for Colorectal Anastomotic Leakage".
    Annals of surgery, 2019, Volume: 269, Issue:5

    Topics: Anastomosis, Surgical; Anastomotic Leak; Colorectal Neoplasms; Humans; Microbiota; Mucus

2019
Butyrylated starch affects colorectal cancer markers beneficially and dose-dependently in genotoxin-treated rats.
    Cancer biology & therapy, 2014, Volume: 15, Issue:11

    Topics: Ammonia; Animals; Apoptosis; Biomarkers; Butyrates; Cell Proliferation; Colorectal Neoplasms; Diet;

2014
Hemidesmosome integrity protects the colon against colitis and colorectal cancer.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adaptive Immunity; Adenocarcinoma; Animals; B-Lymphocytes; Basement Membrane; Caspase 1; Colitis; Co

2017
Isolation of stool-derived mucus provides a high yield of colonocytes suitable for early detection of colorectal carcinoma.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:7

    Topics: Biomarkers, Tumor; Cell Cycle Proteins; Colorectal Neoplasms; Early Detection of Cancer; Feces; Fibr

2009
Who needs colonoscopy to identify colorectal cancer? Bowel symptoms do not add substantially to age and other medical history.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Colonoscopy; Colorectal Ne

2010
Comparison of gastrointestinal symptoms in colorectal carcinoma patients and community controls with respect to age.
    Gut, 1994, Volume: 35, Issue:9

    Topics: Abdominal Pain; Adult; Age Factors; Aged; Aged, 80 and over; Anorexia; Colorectal Neoplasms; Fecal I

1994
Comparison of Shams' test for rectal mucus to an immunological test for fecal occult blood in large intestinal carcinoma screening. Analysis of a check-up of 6480 asymptomatic subjects.
    Chinese medical journal, 1993, Volume: 106, Issue:10

    Topics: Adult; Colorectal Neoplasms; Galactose Oxidase; Humans; Mass Screening; Mucus; Occult Blood; Rectum;

1993
Detection of colorectal neoplasia with peanut-agglutinin (PNA)-reactive carbohydrate structures in rectal mucus.
    International journal of cancer, 1997, Dec-19, Volume: 74, Issue:6

    Topics: Adenoma; Adolescent; Adult; Child; Child, Preschool; Colitis, Ulcerative; Collodion; Colonic Polyps;

1997
In vitro analysis of the role of DCC in mucus-secreting intestinal differentiation.
    International journal of cancer, 1999, May-31, Volume: 81, Issue:5

    Topics: Cell Adhesion Molecules; Cell Differentiation; Cell Division; Cell Polarity; Colorectal Neoplasms; D

1999
Peanut lectin: a mitogen for normal human colonic epithelium and human HT29 colorectal cancer cells.
    Journal of the National Cancer Institute, 1992, Sep-16, Volume: 84, Issue:18

    Topics: Arachis; Carbohydrate Sequence; Cell Division; Colon; Colonoscopy; Colorectal Neoplasms; Diet; Epide

1992
A pilot study on the usefulness of a new test for mass screening of colorectal cancer in Japan.
    Gastroenterologia Japonica, 1990, Volume: 25, Issue:4

    Topics: Biomarkers, Tumor; Colorectal Neoplasms; Humans; Japan; Mass Screening; Mucus; Pilot Projects; Reage

1990
Characterization of a sialic-acid-rich mucus glycoprotein secreted by a premalignant human colorectal adenoma cell line.
    International journal of cancer, 1990, Dec-15, Volume: 46, Issue:6

    Topics: Adenoma; Colorectal Neoplasms; Dithiothreitol; Guanidine; Guanidines; Humans; Mucins; Mucus; Neoplas

1990