guaifenesin and Cirrhosis
guaifenesin has been researched along with Cirrhosis in 21 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The flavonoid naringenin has been shown to attenuate airway inflammation and airway hyper‑reactivity in acute murine models of asthma." | 7.80 | Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma. ( Gu, W; Mao, S; Shi, Y; Tan, Y, 2014) |
| "Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly understood." | 7.78 | Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma. ( Anjos-Valotta, EA; Arantes, AC; Cordeiro, RS; Cotias, AC; Couto, GC; Ferreira, TP; Jurgilas, PB; Martins, MA; Olsen, PC; Pão, CR; Pires, AL; Serra, MF; Silva, PM, 2012) |
| "The flavonoid naringenin has been shown to attenuate airway inflammation and airway hyper‑reactivity in acute murine models of asthma." | 3.80 | Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma. ( Gu, W; Mao, S; Shi, Y; Tan, Y, 2014) |
| "Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly understood." | 3.78 | Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma. ( Anjos-Valotta, EA; Arantes, AC; Cordeiro, RS; Cotias, AC; Couto, GC; Ferreira, TP; Jurgilas, PB; Martins, MA; Olsen, PC; Pão, CR; Pires, AL; Serra, MF; Silva, PM, 2012) |
| "Mice were sensitized to ovalbumin and then repetitively challenged with intranasal ovalbumin for 3 months to develop structural features of airway remodeling including peribronchial fibrosis and increased thickness of the peribronchial smooth muscle layer." | 3.73 | Combination of corticosteroid therapy and allergen avoidance reverses allergen-induced airway remodeling in mice. ( Broide, DH; Cho, JY; McElwain, K; McElwain, S; Miller, M, 2005) |
| " Repetitive ovalbumin challenge of mice deficient in airway epithelial IKKbeta prevented nuclear translocation of the RelA NF-kappaB subunit only in airway epithelial cells, resulting in significantly lower peribronchial fibrosis in CC10-Cre(tg)/Ikkbeta(delta/delta) mice compared with littermate controls as assessed by peribronchial trichrome staining and total lung collagen content." | 3.73 | Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. ( Broide, DH; Cho, JY; Doherty, T; Karin, M; Lawrence, T; McElwain, K; McElwain, S; Miller, M, 2005) |
| " MMP-9-deficient and wild-type (WT) mice were repetitively challenged intranasally with ovalbumin (OVA) antigen to develop features of airway remodeling including peribronchial fibrosis and increased thickness of the peribronchial smooth muscle layer." | 3.73 | Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice. ( Broide, DH; Cho, JY; Lim, DH; McElwain, K; McElwain, S; Miller, M, 2006) |
| "Chronic obstructive pulmonary disease (COPD) is characterized by poorly reversible airflow limitation associated with airway remodelling and inflammation of both large and small airways." | 2.47 | [Structural abnormalities and inflammation in COPD: a focus on small airways]. ( Bourdin, A; Burgel, PR; Chanez, P; Garcia, G; Pilette, C; Tillie-Leblond, I, 2011) |
| "Urothelial villous adenoma is extremely rare, and one should consider neoplastic etiologies, including appendiceal mucinous cystadenocarcinoma and mucus-secreting adenocarcinoma of the renal pelvis, in directing the appropriate management of muconephrosis." | 1.31 | Muconephrosis. ( Deng, DY; Greenberg, MS; Meng, MV; Park, S; Stoller, ML, 2002) |
Research
Studies (21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 13 (61.90) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zabner, J | 1 |
| Birket, SE | 1 |
| Lu, C | 1 |
| Zhang, B | 1 |
| Xu, T | 1 |
| Zhang, W | 1 |
| Bai, B | 1 |
| Xiao, Z | 1 |
| Wu, L | 1 |
| Liang, G | 1 |
| Zhang, Y | 1 |
| Dai, Y | 1 |
| Chalmers, JD | 1 |
| Sibila, O | 1 |
| Steele, H | 1 |
| Sachen, K | 1 |
| McKnight, AJ | 1 |
| Soloff, R | 1 |
| Herro, R | 1 |
| Shi, Y | 1 |
| Tan, Y | 1 |
| Mao, S | 1 |
| Gu, W | 1 |
| Du, Q | 1 |
| Chen, Z | 1 |
| Zhou, LF | 1 |
| Zhang, Q | 1 |
| Huang, M | 1 |
| Yin, KS | 1 |
| Siddiqui, S | 1 |
| Martin, JG | 1 |
| Rey Vázquez, G | 1 |
| Meijide, FJ | 1 |
| Da Cuña, RH | 1 |
| Lo Nostro, FL | 1 |
| Piazza, YG | 1 |
| Babay, PA | 1 |
| Trudeau, VL | 1 |
| Maggese, MC | 1 |
| Guerrero, GA | 1 |
| Song, DJ | 2 |
| Min, MG | 1 |
| Miller, M | 6 |
| Cho, JY | 5 |
| Broide, DH | 6 |
| Lee, SY | 2 |
| Rosenthal, P | 1 |
| Soroosh, P | 1 |
| Croft, M | 1 |
| Zhang, M | 1 |
| Varki, A | 1 |
| Burgel, PR | 1 |
| Bourdin, A | 1 |
| Pilette, C | 1 |
| Garcia, G | 1 |
| Chanez, P | 1 |
| Tillie-Leblond, I | 1 |
| Serra, MF | 1 |
| Anjos-Valotta, EA | 1 |
| Olsen, PC | 1 |
| Couto, GC | 1 |
| Jurgilas, PB | 1 |
| Cotias, AC | 1 |
| Pão, CR | 1 |
| Ferreira, TP | 1 |
| Arantes, AC | 1 |
| Pires, AL | 1 |
| Cordeiro, RS | 1 |
| Silva, PM | 1 |
| Martins, MA | 1 |
| Park, S | 1 |
| Meng, MV | 1 |
| Greenberg, MS | 1 |
| Deng, DY | 1 |
| Stoller, ML | 1 |
| Youn, CJ | 1 |
| Baek, KJ | 1 |
| Han, JW | 1 |
| Nayar, J | 1 |
| McElwain, K | 4 |
| McElwain, S | 4 |
| Raz, E | 1 |
| Lawrence, T | 1 |
| Doherty, T | 1 |
| Karin, M | 1 |
| Lim, DH | 1 |
| Wilson, MS | 1 |
| Elnekave, E | 1 |
| Mentink-Kane, MM | 1 |
| Hodges, MG | 1 |
| Pesce, JT | 1 |
| Ramalingam, TR | 1 |
| Thompson, RW | 1 |
| Kamanaka, M | 1 |
| Flavell, RA | 1 |
| Keane-Myers, A | 1 |
| Cheever, AW | 1 |
| Wynn, TA | 1 |
| Zheng, T | 1 |
| Liu, W | 1 |
| Oh, SY | 1 |
| Zhu, Z | 1 |
| Hu, B | 1 |
| Homer, RJ | 1 |
| Cohn, L | 1 |
| Grusby, MJ | 1 |
| Elias, JA | 1 |
| Kasaian, MT | 1 |
| Miller, DK | 1 |
| Woodson, BT | 1 |
| Garancis, JC | 1 |
| Toohill, RJ | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Measurement of Pharyngeal Sensitivity With the SENSITEST Device: Validation of the Diagnosis Algorithm for Sleep Disordered Breathing[NCT00885573] | 52 participants (Actual) | Interventional | 2008-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for guaifenesin and Cirrhosis
| Article | Year |
|---|---|
Structural aspects of airway remodeling in asthma.
Topics: Animals; Asthma; Cell Proliferation; Cytokines; Epithelial Cells; Extracellular Matrix Proteins; Fib | 2008 |
[Structural abnormalities and inflammation in COPD: a focus on small airways].
Topics: Adaptive Immunity; Airway Remodeling; Apoptosis; Autoimmunity; Bronchioles; Chemotaxis, Leukocyte; C | 2011 |
IL-13 as a therapeutic target for respiratory disease.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Fibrosis; Humans; Inflammation; Interleukin-13; Interleu | 2008 |
Other Studies
18 other studies available for guaifenesin and Cirrhosis
| Article | Year |
|---|---|
ATP12A: Connecting Mucus and Fibrosis in Idiopathic Pulmonary Fibrosis.
Topics: Fibrosis; H(+)-K(+)-Exchanging ATPase; Humans; Idiopathic Pulmonary Fibrosis; Mucus | 2023 |
Piperlongumine reduces ovalbumin‑induced asthma and airway inflammation by regulating nuclear factor‑κB activation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cytokines; Dioxolanes; Fibrosis; Humans; I | 2019 |
Happy Birthday, Bronchiectasis: 200 Years of Targeting Mucus.
Topics: Bronchiectasis; Fibrosis; Humans; Mucus; Respiratory System | 2020 |
Targeting TL1A/DR3 Signaling Offers a Therapeutic Advantage to Neutralizing IL13/IL4Rα in Muco-Secretory Fibrotic Disorders.
Topics: Animals; Asthma; DNA-Binding Proteins; Female; Fibrosis; Interleukin-13; Interleukin-4 Receptor alph | 2021 |
Naringenin inhibits allergen‑induced airway remodeling in a murine model of asthma.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flu | 2014 |
Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma.
Topics: Actins; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Ch | 2008 |
Exposure to waterborne 4-tert-octylphenol induces vitellogenin synthesis and disrupts testis morphology in the South American freshwater fish Cichlasoma dimerus (Teleostei, Perciformes).
Topics: Animals; Argentina; Biomarkers; Dose-Response Relationship, Drug; Endocrine Disruptors; Environmenta | 2009 |
Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen.
Topics: Adrenal Cortex Hormones; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Disease Mod | 2009 |
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.
Topics: Allergens; Animals; Antibodies, Monoclonal; Antigens, Differentiation, Myelomonocytic; Apoptosis; Eo | 2009 |
Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma.
Topics: Anesthetics, Local; Animals; Asthma; Bronchi; Disease Models, Animal; Fibrosis; GATA3 Transcription | 2012 |
Muconephrosis.
Topics: Adenoma, Villous; Aged; Fibrosis; Humans; Kidney; Kidney Neoplasms; Male; Mucus; Nephrectomy; Nephro | 2002 |
Immunostimulatory DNA reverses established allergen-induced airway remodeling.
Topics: Actins; Adjuvants, Immunologic; Allergens; Animals; Antigens, Differentiation; Base Sequence; Bronch | 2004 |
Combination of corticosteroid therapy and allergen avoidance reverses allergen-induced airway remodeling in mice.
Topics: Administration, Intranasal; Adrenal Cortex Hormones; Animals; Bronchi; Bronchial Diseases; Drug Admi | 2005 |
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium.
Topics: Active Transport, Cell Nucleus; Allergens; Animals; Bronchial Diseases; CD4-Positive T-Lymphocytes; | 2005 |
Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice.
Topics: Allergens; Animals; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Chemokines; | 2006 |
IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Fibrosis; Granuloma; Interleukin-10; Interle | 2007 |
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Topics: Animals; Fibrosis; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Interleukin-4; Lung; Meta | 2008 |
Histopathologic changes in snoring and obstructive sleep apnea syndrome.
Topics: Atrophy; Dilatation, Pathologic; Edema; Exocrine Glands; Fibrosis; Humans; Hypertrophy; Male; Metapl | 1991 |