guaifenesin has been researched along with Cholera Infantum in 30 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Research into GI nematode infections has primarily focused on defining the immunological and pathological consequences on host protection." | 2.58 | A sticky end for gastrointestinal helminths; the role of the mucus barrier. ( Grencis, RK; Sharpe, C; Thornton, DJ, 2018) |
| ", concurrent disease, physical or sociopsychologic stress, dietary and genetic status), the intrinsic pharmacokinetic and physicochemical differences in these drugs account for variations in their rate of absorption or uptake from the circulation into the GI mucosa." | 2.37 | Gastrointestinal damage from nonsteroidal anti-inflammatory drugs. ( Rainsford, KD, 1988) |
| "Chronic gastric ulcer is linked to aspirin intake in patients with rheumatic disease, and epidemiologically in all heavy aspirin users; paradoxically, in only one epidemiologic study was a significant association found between acetaminophen intake and chronic gastric ulcer." | 2.36 | Gastrointestinal effects of antipyretic analgesics. ( Ivey, KJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (40.00) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sauvaitre, T | 1 |
| Etienne-Mesmin, L | 1 |
| Sivignon, A | 1 |
| Mosoni, P | 1 |
| Courtin, CM | 1 |
| Van de Wiele, T | 1 |
| Blanquet-Diot, S | 1 |
| Sharpe, C | 1 |
| Thornton, DJ | 1 |
| Grencis, RK | 1 |
| Johansson, ME | 1 |
| Sjövall, H | 1 |
| Hansson, GC | 1 |
| Yandrapu, H | 1 |
| Sarosiek, J | 2 |
| Saegusa, Y | 1 |
| Ichikawa, T | 1 |
| Iwai, T | 1 |
| Goso, Y | 1 |
| Okayasu, I | 1 |
| Ikezawa, T | 1 |
| Shikama, N | 1 |
| Saigenji, K | 1 |
| Ishihara, K | 1 |
| Prakash, UN | 1 |
| Srinivasan, K | 1 |
| McGuckin, MA | 1 |
| Lindén, SK | 1 |
| Sutton, P | 1 |
| Florin, TH | 1 |
| Boleij, A | 1 |
| Tjalsma, H | 1 |
| HOSKINS, LC | 1 |
| ZAMCHECK, N | 1 |
| Gindzienski, A | 1 |
| Zwierz, K | 1 |
| Strompfová, V | 1 |
| Lauková, A | 1 |
| Ouwehand, AC | 1 |
| Ivey, KJ | 1 |
| Guslandi, M | 1 |
| Forstner, G | 1 |
| Wesley, A | 1 |
| Forstner, J | 1 |
| Sty, JR | 1 |
| Starshak, RJ | 1 |
| Lauer, SJ | 1 |
| Pinnock, CB | 2 |
| Arney, WK | 2 |
| Bengtsson, U | 1 |
| Hanson, LA | 1 |
| Ahlstedt, S | 1 |
| Busca, M | 1 |
| Calatayud, S | 1 |
| Barrachina, D | 1 |
| Esplugues, JV | 1 |
| Schopf, LR | 1 |
| Hoffmann, KF | 1 |
| Cheever, AW | 1 |
| Urban, JF | 1 |
| Wynn, TA | 1 |
| Schrager, J | 1 |
| Oates, MD | 1 |
| Wood, RE | 1 |
| Boat, TF | 1 |
| Doershuk, CF | 1 |
| Bowman, BH | 1 |
| Glass, GB | 1 |
| Slomiany, BL | 1 |
| Pasquier, MC | 1 |
| Vatier, J | 1 |
| Talley, NJ | 1 |
| Phillips, SF | 1 |
| Melton, LJ | 1 |
| Mulvihill, C | 1 |
| Wiltgen, C | 1 |
| Zinsmeister, AR | 1 |
| Munster, DJ | 1 |
| Roberton, AM | 1 |
| Bagshaw, PF | 1 |
| Rainsford, KD | 1 |
| Faure, J | 1 |
| Sibille, M | 1 |
| Faure, H | 1 |
| Stephan, C | 1 |
| Yacoub, M | 1 |
| Motin, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Efficacy and Safety of Rifaximin in Combination With N-acetylcysteine (NAC) in Adult Patients With Irritable Bowel Syndrome With Diarrhea[NCT04557215] | Phase 1/Phase 2 | 45 participants (Actual) | Interventional | 2020-11-13 | Completed | ||
| A Single Arm 48-Week Follow-on Safety Study to the Core Study (A Multicentre, Multinational, Open-Label, Randomised, Parallel Group Clinical Trial of Tobrineb®/Actitob®/Bramitob® (Tobramycin Solution for Nebulisation, 300mg Twice Daily in 4mL Unit Dose Vi[NCT01111383] | Phase 3 | 209 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Change in severity of abdominal pain from baseline, as determined from weekly average visual analog scale (VAS) scores, relative to Rifaximin alone. VAS scores allows subject to choose 0 for no pain to 100 pain as bad as it could possibly be.~The Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 no pain and 100 pain as bad as it could possibly be~The change between two time points is reported baseline and 4 weeks after cessation of treatment (at 6 weeks)" (NCT04557215)
Timeframe: value at 6 weeks minus value at baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Rifaximin 550 mg | -5.43 |
| Rifaximin 200 mg + Placebo | -8.90 |
| Rifaximin 200 mg Plus N-acetylcysteine (NAC) 600 mg Days | -5.59 |
"Change in stool form from baseline, as determined from stool diary data comparing Rifaximin alone vs rifaximin and NAC~The Bristol Stool Chart, the minimum value is 1 (means constipation) and maximum value is 7 (means diarrhea).~The change between two time points is reported baseline and 4 weeks after cessation of treatment (at 6 weeks)" (NCT04557215)
Timeframe: value at 6 weeks minus value at baseline
| Intervention | score on a scale (Mean) |
|---|---|
| Rifaximin 550 mg | -0.26 |
| Rifaximin 200 mg + Placebo | -0.45 |
| Rifaximin 200 mg Plus N-acetylcysteine (NAC) 600 mg Days | -0.49 |
"Change in stool frequency from baseline, as determined from diary data comparing Rifaximin alone vs Rifaximin and NAC~determined from daily stool diary data~The change in bowel movements/day between two time points is reported baseline and 4 weeks after cessation of treatment (at 6 weeks)" (NCT04557215)
Timeframe: value at 6 weeks minus value at baseline
| Intervention | number of bowel movements (Mean) |
|---|---|
| Rifaximin 550 mg | -0.04 |
| Rifaximin 200 mg + Placebo | -0.50 |
| Rifaximin 200 mg Plus N-acetylcysteine (NAC) 600 mg Days | -0.24 |
15 reviews available for guaifenesin and Cholera Infantum
| Article | Year |
|---|---|
Tripartite relationship between gut microbiota, intestinal mucus and dietary fibers: towards preventive strategies against enteric infections.
Topics: Dietary Fiber; Gastrointestinal Diseases; Gastrointestinal Microbiome; Humans; Intestines; Mucus | 2021 |
A sticky end for gastrointestinal helminths; the role of the mucus barrier.
Topics: Animals; Gastrointestinal Diseases; Goblet Cells; Immunity, Innate; Mice; Mucins; Mucus; Nematoda; N | 2018 |
The gastrointestinal mucus system in health and disease.
Topics: Colitis; Colon; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Intestine, Small; Mucus; | 2013 |
Protective Factors of the Gastric and Duodenal Mucosa: An Overview.
Topics: Duodenum; Gastric Mucosa; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Mucus; Stomach | 2015 |
Mucin dynamics and enteric pathogens.
Topics: Adaptive Immunity; Animals; Bacterial Infections; Gastric Mucosa; Gastrointestinal Diseases; Gastroi | 2011 |
Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer.
Topics: Colorectal Neoplasms; Diet; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Mucus | 2012 |
Gastrointestinal effects of antipyretic analgesics.
Topics: Acetaminophen; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonate | 1983 |
Clinical aspects of gastrointestinal mucus.
Topics: Adenocarcinoma; Antigens; Cholelithiasis; Cholera Toxin; Cystic Fibrosis; Digestive System; Gastroen | 1982 |
Nitric oxide: relation to integrity, injury, and healing of the gastric mucosa.
Topics: Animals; Apoptosis; Bicarbonates; Gastric Acid; Gastric Mucosa; Gastrointestinal Diseases; Humans; I | 2001 |
Relation of human gastrointestinal mucus to disease states.
Topics: Anemia, Pernicious; Colon; Colonic Neoplasms; Gastric Mucosa; Gastrointestinal Diseases; Glycoprotei | 1978 |
Cystic fibrosis.
Topics: Biological Transport; Cystic Fibrosis; Exocrine Glands; Female; Gastrointestinal Diseases; Genital D | 1976 |
Current biochemical approaches in cystic fibrosis research.
Topics: Biological Transport; Cilia; Cystic Fibrosis; Gastrointestinal Diseases; Glycoproteins; Heterozygote | 1976 |
[The gastrointestinal mucus: a complex protective barrier. 2: Physiopathology of the gastroduodenal mucus].
Topics: Animals; Digestive System; Digestive System Physiological Phenomena; Duodenogastric Reflux; Gastric | 1990 |
Mucus has many roles in the gastrointestinal tract in health and disease.
Topics: Animals; Digestive System Physiological Phenomena; Gastrointestinal Diseases; Humans; Mucus | 1989 |
Gastrointestinal damage from nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Environment; Free Radicals; Gastric | 1988 |
1 trial available for guaifenesin and Cholera Infantum
| Article | Year |
|---|---|
The milk-mucus belief: sensory analysis comparing cow's milk and a soy placebo.
Topics: Animals; Attitude; Cattle; Double-Blind Method; Food, Formulated; Gastrointestinal Diseases; Glycine | 1993 |
14 other studies available for guaifenesin and Cholera Infantum
| Article | Year |
|---|---|
Changes in the mucus barrier of the rat during 5-fluorouracil-induced gastrointestinal mucositis.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Fluorouracil; Gastrointestinal Disea | 2008 |
Gastrointestinal protective effect of dietary spices during ethanol-induced oxidant stress in experimental rats.
Topics: Alkaloids; Animals; Antioxidants; Benzodioxoles; Capsaicin; Capsicum; Catalase; Cytoprotection; Diet | 2010 |
STUDIES ON GASTRIC MUCUS IN HEALTH AND DISEASE. II. EVIDENCE FOR A CORRELATION BETWEEN ABO BLOOD GROUP SPECIFICITY, ABH(O) SECRETOR STATUS, AND THE FUCOSE CONTENT OF THE GLYCOPROTEINS ELABORATED BY THE GASTRIC MUCOSA.
Topics: ABO Blood-Group System; Chemical Phenomena; Chemistry; Fucose; Gastric Juice; Gastric Mucins; Gastri | 1965 |
The role of mucus and its components in protection and repair within the alimentary tract mucosa: Polish experience.
Topics: Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; History, 20th Century; Humans; In | 2003 |
Lactobacilli and enterococci--potential probiotics for dogs.
Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Antibiosis; Bacterial Adhesion; Bacteriocins; | 2004 |
Evaluation of gastric mucus in man by means of the "mucoprotective index": a review of a five-year experience with this method.
Topics: Gastric Mucosa; Gastrointestinal Diseases; Humans; Methods; Mucoproteins; Mucus | 1983 |
Polymucositis: a cause of Ga-67 uptake.
Topics: Child; Diagnosis, Differential; Doxorubicin; Esophagus; Gallium Radioisotopes; Gastrointestinal Dise | 1981 |
The milk mucus belief: sensations associated with the belief and characteristics of believers.
Topics: Animals; Attitude; Australia; Deglutition; Gastrointestinal Diseases; Humans; Middle Aged; Milk; Muc | 1993 |
Survey of gastrointestinal reactions to foods in adults in relation to atopy, presence of mucus in the stools, swelling of joints and arthralgia in patients with gastrointestinal reactions to foods.
Topics: Adolescent; Adult; Antigen-Antibody Complex; Arthralgia; Arthritis; Feces; Female; Food; Food Hypers | 1996 |
[A new system for noninvasive sampling of the upper gastrointestinal tract].
Topics: Adult; Capsules; Child; Endoscopy; Evaluation Studies as Topic; Gastrointestinal Diseases; Gastroint | 1999 |
IL-10 is critical for host resistance and survival during gastrointestinal helminth infection.
Topics: Animals; Anti-Bacterial Agents; Cecum; Cells, Cultured; Cytokines; Gastrointestinal Diseases; Interf | 2002 |
Derangements of biosynthesis, production and secretion of mucus in gastrointestinal injury and disease.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Neoplasm; Colonic Diseases; Digestive System; Ethanol; | 1977 |
Diagnostic value of the Manning criteria in irritable bowel syndrome.
Topics: Colonic Diseases, Functional; Defecation; Diagnosis, Differential; Dyspepsia; Evaluation Studies as | 1990 |
[Acute chlorine and phosgene poisoning (clinical and experimental study)].
Topics: Adult; Animals; Apnea; Chlorine; Eye Diseases; Gas Poisoning; Gastrointestinal Diseases; Guinea Pigs | 1970 |