Page last updated: 2024-10-28

guaifenesin and Cholelithiasis

guaifenesin has been researched along with Cholelithiasis in 43 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).

Research Excerpts

Excerpt	Relevance	Reference
"In three models of cholelithiasis (dihydrocholesterol-fed rabbits, cholesterol-cholic acid-fed mice, and Lincomycin-treated guinea pigs), the quantity and chemical composition of gallbladder epithelial mucin have been studied using (1) a spectrum of histochemical glycoprotein stains, and (2) biochemical extraction, purification and analysis of the carbohydrate components of epithelial mucin."	3.66	Hypersecretion of mucus glycoprotein by the gallbladder epithelium in experimental cholelithiasis. ( Lee, SP, 1981)
"Treatment with aspirin led to a significant reduction in mucus biosynthesis by the gall bladder mucosa."	2.67	Inhibition of human gall bladder mucus synthesis in patients undergoing cholecystectomy. ( Allen, A; Dowling, RH; Lennard, TW; Murphy, G; Rhodes, M, 1992)

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (62.79)	18.7374
1990's	16 (37.21)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
LAUBE, J	1
WEISE, G	1
Samar, ME	1
Schneider, NO	1
Somaré, L	1
Avila, RE	1
de Fabro, SP	1
Lee, SP	4
Doty, JE	1
Pitt, HA	1
Kuchenbecker, SL	1
Porter-Fink, V	1
DenBesten, LW	1
Forstner, G	1
Wesley, A	1
Forstner, J	1
Pearson, JP	2
Kaura, R	1
Taylor, W	1
Allen, A	2
LaMont, JT	1
Carey, MC	1
Gilloteaux, J	5
Karkare, S	3
Kelly, TR	3
Moser, AJ	1
Abedin, MZ	1
Roslyn, JJ	1
Rege, RV	2
Prystowsky, JB	2
Hawkins, WS	2
Gilloteaux, LC	1
Jasso, J	1
MacPherson, BR	1
Pemsingh, RS	1
Don, AQ	1
Sexton, RC	1
Englert, E	1
Harman, CG	1
Freston, JW	3
Straight, RC	1
Wales, EE	1
Schorn, K	1
Hochstrasser, K	1
Pasemann, V	1
Paraf, A	1
Rauturea, J	1
Gouffier, E	1
Boddaert, A	1
Rhodes, M	1
Dowling, RH	1
Murphy, G	1
Lennard, TW	1
Sakata, R	1
Carlei, F	1
Lygidakis, NJ	1
Barsotti, P	1
Crescenzi, A	1
Natellis, C	1
Carotenuto, F	1
Dorsi, E	1
Casciani, CU	1
Pattinson, NR	1
Willis, KE	1
Smith, BF	1
Saito, K	1
Nakanuma, Y	2
Haley-Russell, D	1
Husband, KJ	1
Moody, FG	2
Terada, T	1
Foster, SN	1
Li, YF	1
Weisbrodt, NW	1
Zalewsky, CA	1
Coelho, JC	1
Senninger, N	1
Gouma, D	1
Nicholls, JF	1
Harvey, PR	1
Rupar, CA	1
Gallinger, S	1
Petrunka, CN	1
Strasberg, SM	1
Maki, T	1
Matsushiro, T	1
Suzuki, N	1
Nakamura, N	1
Bouchier, IA	5
Newman, J	1
Fox, H	1
Hultén, O	2
Womack, NA	1
Ely, JW	1
Hall, RC	1
Tepperman, J	1
Hayward, AF	1
Cooperband, SR	1
el-Kodsi, BM	1

Reviews

5 reviews available for guaifenesin and Cholelithiasis

Article	Year
Clinical aspects of gastrointestinal mucus. Advances in experimental medicine and biology, 1982, Volume: 144 Topics: Adenocarcinoma; Antigens; Cholelithiasis; Cholera Toxin; Cystic Fibrosis; Digestive System; Gastroen	1982
The pathogenesis of gallstone formation. Advances in surgery, 1993, Volume: 26 Topics: Absorption; Bile; Calcium; Cholelithiasis; Cholesterol; Humans; Mucus; Pigmentation; Prostaglandins	1993
Introduction to the biliary tract, the gallbladder, and gallstones. Microscopy research and technique, 1997, Sep-15, Volume: 38, Issue:6 Topics: Animals; Bile Acids and Salts; Biliary Tract; Cholelithiasis; Gallbladder; Humans; Lymphatic System;	1997
Gallbladder mucin as a pronucleating agent for cholesterol monohydrate crystals in bile. Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:3 Pt 2 Topics: Animals; Chemical Phenomena; Chemistry; Cholelithiasis; Cholesterol; Crystallization; Gallbladder; H	1990
The biochemistry of gallstone formation. Clinics in gastroenterology, 1973, Volume: 2, Issue:1 Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholic Acids; Crysta	1973

Trials

1 trial available for guaifenesin and Cholelithiasis

Article	Year
Inhibition of human gall bladder mucus synthesis in patients undergoing cholecystectomy. Gut, 1992, Volume: 33, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Bile; Cholelithiasis; Cholesterol; Depression, Chemical; Fe	1992

Other Studies

37 other studies available for guaifenesin and Cholelithiasis

Article	Year
[ON 2 CASES OF EMPYEMA OF THE GALLBLADDER IN MUCOCELE OF THE APPENDIX]. Zentralblatt fur Chirurgie, 1964, Mar-21, Volume: 89 Topics: Appendicitis; Appendix; Cholecystitis; Cholelithiasis; Empyema; Humans; Mucocele; Mucus	1964
[Cytochemical characteristics of mucus in lithiasic gallbladders]. Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 1983, Volume: 41, Issue:3-4 Topics: Cholelithiasis; Gallbladder; Humans; Mucus	1983
Hypersecretion of mucus glycoprotein by the gallbladder epithelium in experimental cholelithiasis. The Journal of pathology, 1981, Volume: 134, Issue:3 Topics: Animals; Cholelithiasis; Cholestanol; Cholesterol; Cholic Acids; Disease Models, Animal; Epithelium;	1981
Role of gallbladder mucus in the pathogenesis of cholesterol gallstones. American journal of surgery, 1983, Volume: 145, Issue:1 Topics: Animals; Bile; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Gallbladder; Liver; Male; Models,	1983
The composition and polymeric structure of mucus glycoprotein from human gallbladder bile. Biochimica et biophysica acta, 1982, Sep-07, Volume: 706, Issue:2 Topics: Amino Acids; Bile; Carbohydrates; Cholelithiasis; Chromatography, Gel; Gallbladder; Glycoproteins; H	1982
Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. The Journal of clinical investigation, 1981, Volume: 67, Issue:6 Topics: Animals; Bile; Cholelithiasis; Cholesterol, Dietary; Chromatography; Dogs; Gallbladder; Glucosamine;	1981
Apical excrescences in the gallbladder epithelium of the female Syrian hamster in response to medroxyprogesterone. The Anatomical record, 1993, Volume: 236, Issue:3 Topics: Animals; Bile; Cholelithiasis; Cholesterol; Cricetinae; Epithelium; Female; Gallbladder; Medroxyprog	1993
Inflammatory properties of bile from dogs with pigment gallstones. American journal of surgery, 1996, Volume: 171, Issue:1 Topics: Animals; Bile; Bile Pigments; Cholecystitis; Cholelithiasis; Dogs; Female; Guinea Pigs; Interleukin-	1996
Ultrastructural aspects of human cystic duct epithelium as a result of cholelithiasis and cholesterolosis. Microscopy research and technique, 1997, Oct-01, Volume: 39, Issue:1 Topics: Adult; Aged; Child; Cholelithiasis; Cholesterol; Cystic Duct; Epithelial Cells; Epithelium; Female;	1997
Ground squirrel model for cholelithiasis: role of epithelial glycoproteins. Microscopy research and technique, 1997, Oct-01, Volume: 39, Issue:1 Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Calcium; Cholelithiasi	1997
Cholelithiasis induced in the Syrian hamster: evidence for an intramucinous nucleating process and down regulation of cholesterol 7 alpha-hydroxylase (CYP7) gene by medroxyprogesterone. Microscopy research and technique, 1997, Oct-01, Volume: 39, Issue:1 Topics: Acyl Coenzyme A; Animals; Bile; Cholelithiasis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cricet	1997
Ultrastructural aspects of human gallbladder epithelial cells in cholelithiasis: production of anionic mucus. Microscopy research and technique, 1997, Sep-15, Volume: 38, Issue:6 Topics: Adult; Aged; Animals; Cholelithiasis; Cricetinae; Epithelial Cells; Female; Gallbladder; Humans; Mes	1997
Inflammation and a thickened mucus layer in mice with cholesterol gallstones. The Journal of surgical research, 1998, Volume: 74, Issue:1 Topics: Animals; Cholecystitis; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids	1998
Studies on the pathogenesis of diet-induced dog gallstones. The American journal of digestive diseases, 1977, Volume: 22, Issue:4 Topics: Amino Acids; Animals; Bile; Bile Pigments; Bilirubin; Cholelithiasis; Cholesterol, Dietary; Diet; Di	1977
[Rate of transudation of the mucous membranes by testing the enzymes of the intermediary metabolism in the secretion of patients with different internal diseases (author's transl)]. Laryngologie, Rhinologie, Otologie, 1975, Volume: 54, Issue:8 Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cholelithiasis; Creatine Ki	1975
[Letter: Initial stage of cholelithiasis in man. Role of the gallbladder mucus]. La Nouvelle presse medicale, 1976, May-08, Volume: 5, Issue:19 Topics: Adolescent; Cholelithiasis; Female; Humans; Male; Mucous Membrane; Mucus	1976
[Morphological changes of extrahepatic bile ductal epithelia in hamsters feeded with lithogenic diet]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1992, Volume: 89, Issue:10 Topics: Animal Feed; Animals; Bile Ducts; Cholelithiasis; Cricetinae; Epithelium; Male; Mesocricetus; Mucus	1992
Mucin-producing cells and endocrine cells of gallbladder epithelium in patients with uncomplicated cholelithiasis. Hepato-gastroenterology, 1991, Volume: 38, Issue:2 Topics: Cholelithiasis; Epithelium; Female; Gallbladder; Humans; Immunoenzyme Techniques; Middle Aged; Mucin	1991
Lessons from experimental cholelithiasis: gallbladder and mucosa, nonsteroidal antiinflammatory drugs, and gallstones. Gastroenterology, 1991, Volume: 101, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholelithiasis; Cholesterol; Gallbladder; Glycopro	1991
Nucleation of cholesterol crystals from native bile and the effect of protein hydrolysis. Journal of lipid research, 1991, Volume: 32, Issue:2 Topics: Bile; Cholelithiasis; Cholesterol; Chromatography, Gel; Crystallization; Glycoproteins; Humans; Hydr	1991
Lectin binding of intrahepatic bile ducts and peribiliary glands in normal livers and hepatolithiasis. The Tohoku journal of experimental medicine, 1990, Volume: 160, Issue:1 Topics: Bile Ducts, Intrahepatic; Cholelithiasis; Exocrine Glands; Glycoproteins; Histocytochemistry; Humans	1990
Morphology of the prairie dog gallbladder: normal characteristics and changes during early lithogenesis. The American journal of anatomy, 1989, Volume: 186, Issue:2 Topics: Animals; Bile; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cystic Duct; Gallbladder; Male; Mi	1989
Morphological examination of intrahepatic bile ducts in hepatolithiasis. Virchows Archiv. A, Pathological anatomy and histopathology, 1988, Volume: 413, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Bile Ducts, Intrahepatic; Cholangiography; Cholelithiasis; Exocrine	1988
Mucus glycoprotein content of human cholesterol gallstones. Digestion, 1987, Volume: 36, Issue:3 Topics: Cholelithiasis; Cholesterol; Chromatography, Gel; Glycoproteins; Humans; Molecular Weight; Mucus	1987
Gallbladder contractility and mucus secretion after cholesterol feeding in the prairie dog. Surgery, 1986, Volume: 100, Issue:5 Topics: Animals; Cholelithiasis; Cholesterol, Dietary; Gallbladder; Mucus; Muscle Contraction; Muscle, Smoot	1986
Nature and composition of biliary sludge. Gastroenterology, 1986, Volume: 90, Issue:3 Topics: Adult; Aged; Bile; Bilirubin; Cholelithiasis; Cholesterol; Crystallization; Female; Gallbladder; Gly	1986
Quantitative and qualitative comparison of gall bladder mucus glycoprotein from patients with and without gall stones. Gut, 1986, Volume: 27, Issue:4 Topics: Amino Acids; Bile; Carbohydrates; Cholelithiasis; Cholesterol; Gallbladder; Glycoproteins; Humans; L	1986
Role of sulfated glycoprotein in gallstone formation. Surgery, gynecology & obstetrics, 1971, Volume: 132, Issue:5 Topics: Animals; Bile; Bilirubin; Calcium Carbonate; Cholelithiasis; Cholesterol; Chondroitin; Chromatograph	1971
Biliary mucous substances in dihydrocholesterol-induced cholelithiasis. Gastroenterology, 1969, Volume: 57, Issue:6 Topics: Animals; Cholelithiasis; Dihydrotachysterol; Gallbladder; Glycoproteins; Glycosaminoglycans; Hexosam	1969
Ultrastructure of the human gall-bladder epithelium in cholelithiasis and chronic cholecystitis. The Journal of pathology, 1972, Volume: 108, Issue:2 Topics: Cholecystitis; Cholelithiasis; Chronic Disease; Epithelial Cells; Epithelium; Gallbladder; Golgi App	1972
Formation of gallstones. II. Acta chirurgica Scandinavica, 1968, Volume: 134, Issue:7 Topics: Anatomy, Comparative; Animals; Bile; Cholelithiasis; Gallbladder; Gels; Haplorhini; Humans; Models,	1968
The development of gallstones. Surgery, gynecology & obstetrics, 1971, Volume: 133, Issue:6 Topics: Acid-Base Equilibrium; Animals; Cholelithiasis; Cholesterol; Cricetinae; Crystallization; Diet; Fema	1971
Mucus production in gallstone formation--autoradiographs using tritiated galactose. Surgical forum, 1971, Volume: 22 Topics: Animals; Autoradiography; Cholelithiasis; Galactose; Gallbladder; Glycoproteins; Hyperplasia; Mice;	1971
Changes in the ultrastructure of gall bladder epithelium in rabbits with experimental gallstones. Gut, 1968, Volume: 9, Issue:5 Topics: Animals; Cholelithiasis; Diet; Epithelium; Female; Gallbladder; Male; Microscopy, Electron; Mucus; R	1968
Formation of gallstones. I. Acta chirurgica Scandinavica, 1968, Volume: 134, Issue:2 Topics: Cholelithiasis; Cystoscopy; Gallbladder; Gels; Humans; Models, Structural; Mucous Membrane; Mucus; P	1968
Mucous substances and viscosity of normal and pathological human bile. Gastroenterology, 1965, Volume: 49, Issue:4 Topics: Adult; Aged; Bile; Bilirubin; Chemistry Techniques, Analytical; Cholelithiasis; Female; Glycoprotein	1965
Macromolecular material in bile and its relationship to gallstone formation. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, Aug-20, Volume: 40, Issue:31 Topics: Bile; Bile Acids and Salts; Cholelithiasis; Cholesterol; Chromatography, Gel; Humans; Macromolecular	1966