guaifenesin has been researched along with Bowel Diseases, Inflammatory in 45 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arctigenin was demonstrated to promote the mucus secretion and maintain the integrity of mucus barrier, which might be achieved by an increase in the number of goblet cells via inhibiting apoptosis." | 5.72 | Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway. ( Dai, Y; Fang, YL; Lv, CJ; Qiao, SM; Tao, Y; Wei, ZF; Xia, YF; Yue, MF; Yun, XM, 2022) |
| " Nonetheless, these drugs suffer from severe side effects or poor efficacy due to low bioavailability in the inflamed region of the intestinal tract." | 2.82 | Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems. ( Bouchemal, K; Hadji, H, 2022) |
| "Arctigenin was demonstrated to promote the mucus secretion and maintain the integrity of mucus barrier, which might be achieved by an increase in the number of goblet cells via inhibiting apoptosis." | 1.72 | Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway. ( Dai, Y; Fang, YL; Lv, CJ; Qiao, SM; Tao, Y; Wei, ZF; Xia, YF; Yue, MF; Yun, XM, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.89) | 18.2507 |
| 2000's | 6 (13.33) | 29.6817 |
| 2010's | 22 (48.89) | 24.3611 |
| 2020's | 13 (28.89) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 2 |
| Shen, X | 1 |
| Zhou, Q | 1 |
| Zhan, Q | 1 |
| Xu, X | 1 |
| Chen, Q | 1 |
| An, F | 1 |
| Sun, J | 1 |
| Fernández-Tomé, S | 1 |
| Ortega Moreno, L | 1 |
| Chaparro, M | 1 |
| Gisbert, JP | 1 |
| Reyes Nicolás, V | 1 |
| Allaire, JM | 2 |
| Alfonso, AB | 1 |
| Pupo Gómez, D | 1 |
| Pomerleau, V | 1 |
| Giroux, V | 1 |
| Boudreau, F | 1 |
| Perreault, N | 1 |
| Stiegeler, S | 1 |
| Mercurio, K | 1 |
| Iancu, MA | 1 |
| Corr, SC | 1 |
| Hadji, H | 1 |
| Bouchemal, K | 1 |
| Yao, Y | 1 |
| Kim, G | 1 |
| Shafer, S | 1 |
| Kubo, S | 1 |
| Ji, Y | 1 |
| Luo, J | 1 |
| Yang, W | 1 |
| Perner, SP | 1 |
| Kanellopoulou, C | 1 |
| Park, AY | 1 |
| Jiang, P | 1 |
| Li, J | 1 |
| Baris, S | 1 |
| Aydiner, EK | 1 |
| Ertem, D | 1 |
| Mulder, DJ | 1 |
| Warner, N | 1 |
| Griffiths, AM | 1 |
| Topf-Olivestone, C | 1 |
| Kori, M | 1 |
| Werner, L | 1 |
| Ouahed, J | 1 |
| Field, M | 1 |
| Liu, C | 1 |
| Schwarz, B | 1 |
| Bosio, CM | 1 |
| Ganesan, S | 1 |
| Song, J | 1 |
| Urlaub, H | 1 |
| Oellerich, T | 1 |
| Malaker, SA | 1 |
| Zheng, L | 1 |
| Bertozzi, CR | 1 |
| Zhang, Y | 1 |
| Matthews, H | 1 |
| Montgomery, W | 1 |
| Shih, HY | 1 |
| Jiang, J | 1 |
| Jones, M | 1 |
| Baras, A | 1 |
| Shuldiner, A | 1 |
| Gonzaga-Jauregui, C | 1 |
| Snapper, SB | 1 |
| Muise, AM | 1 |
| Shouval, DS | 1 |
| Ozen, A | 1 |
| Pan, KT | 1 |
| Wu, C | 1 |
| Lenardo, MJ | 1 |
| Nooredinvand, HA | 1 |
| Poullis, A | 2 |
| Tao, Y | 1 |
| Qiao, SM | 1 |
| Lv, CJ | 1 |
| Yun, XM | 1 |
| Yue, MF | 1 |
| Fang, YL | 1 |
| Wei, ZF | 1 |
| Dai, Y | 1 |
| Xia, YF | 1 |
| Wu, Z | 1 |
| Liu, X | 1 |
| Huang, S | 1 |
| Li, T | 1 |
| Zhang, X | 2 |
| Pang, J | 1 |
| Zhao, J | 1 |
| Chen, L | 1 |
| Zhang, B | 1 |
| Wang, J | 1 |
| Han, D | 1 |
| Song, C | 1 |
| Chai, Z | 1 |
| Chen, S | 1 |
| Zhang, H | 1 |
| Zhou, Y | 1 |
| Volk, JK | 1 |
| Nyström, EEL | 1 |
| van der Post, S | 1 |
| Abad, BM | 1 |
| Schroeder, BO | 1 |
| Johansson, Å | 1 |
| Svensson, F | 1 |
| Jäverfelt, S | 1 |
| Johansson, MEV | 1 |
| Hansson, GC | 1 |
| Birchenough, GMH | 1 |
| Paone, P | 1 |
| Cani, PD | 1 |
| Placet, M | 1 |
| Molle, CM | 1 |
| Arguin, G | 1 |
| Geha, S | 1 |
| Gendron, FP | 1 |
| Al-Shaibi, AA | 1 |
| Abdel-Motal, UM | 1 |
| Hubrack, SZ | 1 |
| Bullock, AN | 1 |
| Al-Marri, AA | 1 |
| Agrebi, N | 1 |
| Al-Subaiey, AA | 1 |
| Ibrahim, NA | 1 |
| Charles, AK | 1 |
| Elawad, M | 1 |
| Uhlig, HH | 1 |
| Lo, B | 1 |
| Capaldo, CT | 1 |
| Powell, DN | 1 |
| Kalman, D | 1 |
| Hecht, AL | 1 |
| Casterline, BW | 1 |
| Choi, VM | 1 |
| Bubeck Wardenburg, J | 1 |
| Mizoguchi, A | 1 |
| Yano, A | 1 |
| Himuro, H | 1 |
| Ezaki, Y | 1 |
| Sadanaga, T | 1 |
| Mizoguchi, E | 1 |
| Morampudi, V | 1 |
| Crowley, SM | 1 |
| Stahl, M | 1 |
| Yu, H | 1 |
| Bhullar, K | 1 |
| Knodler, LA | 1 |
| Bressler, B | 1 |
| Jacobson, K | 1 |
| Vallance, BA | 1 |
| Wu, HM | 1 |
| Wei, J | 1 |
| Wang, K | 1 |
| Qi, Y | 1 |
| Wang, FY | 1 |
| Date, AA | 1 |
| Halpert, G | 1 |
| Babu, T | 1 |
| Ortiz, J | 1 |
| Kanvinde, P | 1 |
| Dimitrion, P | 1 |
| Narayan, J | 1 |
| Zierden, H | 1 |
| Betageri, K | 1 |
| Musmanno, O | 1 |
| Wiegand, H | 1 |
| Huang, X | 1 |
| Gumber, S | 1 |
| Hanes, J | 1 |
| Ensign, LM | 1 |
| Ring, C | 1 |
| Klopfleisch, R | 1 |
| Dahlke, K | 1 |
| Basic, M | 1 |
| Bleich, A | 1 |
| Blaut, M | 1 |
| Chuang, LS | 1 |
| Morrison, J | 1 |
| Hsu, NY | 1 |
| Labrias, PR | 1 |
| Nayar, S | 1 |
| Chen, E | 1 |
| Villaverde, N | 1 |
| Facey, JA | 1 |
| Boschetti, G | 1 |
| Giri, M | 1 |
| Castillo-Martin, M | 1 |
| Thin, TH | 1 |
| Sharma, Y | 1 |
| Chu, J | 1 |
| Cho, JH | 1 |
| Hardy, H | 1 |
| Harris, J | 1 |
| Lyon, E | 1 |
| Beal, J | 1 |
| Foey, AD | 1 |
| Klag, T | 1 |
| Stange, EF | 1 |
| Wehkamp, J | 1 |
| Huang, Z | 1 |
| Wang, Z | 1 |
| Long, S | 1 |
| Jiang, H | 2 |
| Chen, J | 1 |
| Zhang, J | 1 |
| Dong, L | 1 |
| Theodoratou, E | 1 |
| Campbell, H | 1 |
| Ventham, NT | 1 |
| Kolarich, D | 1 |
| Pučić-Baković, M | 1 |
| Zoldoš, V | 1 |
| Fernandes, D | 1 |
| Pemberton, IK | 1 |
| Rudan, I | 1 |
| Kennedy, NA | 1 |
| Wuhrer, M | 1 |
| Nimmo, E | 1 |
| Annese, V | 1 |
| McGovern, DP | 1 |
| Satsangi, J | 1 |
| Lauc, G | 1 |
| Johansson, ME | 1 |
| Pookhao, N | 1 |
| Sohn, MB | 1 |
| Li, Q | 1 |
| Jenkins, I | 1 |
| Du, R | 1 |
| An, L | 1 |
| Goll, R | 1 |
| van Beelen Granlund, A | 1 |
| Gouyer, V | 1 |
| Dubuquoy, L | 1 |
| Robbe-Masselot, C | 1 |
| Neut, C | 1 |
| Singer, E | 1 |
| Plet, S | 1 |
| Geboes, K | 1 |
| Desreumaux, P | 1 |
| Gottrand, F | 1 |
| Desseyn, JL | 1 |
| Loktionov, A | 1 |
| Chhaya, V | 1 |
| Bandaletova, T | 1 |
| Glade, MJ | 1 |
| Meguid, MM | 1 |
| Qin, X | 2 |
| Corazziari, ES | 1 |
| Fyderek, K | 1 |
| Strus, M | 1 |
| Kowalska-Duplaga, K | 1 |
| Gosiewski, T | 1 |
| Wedrychowicz, A | 1 |
| Jedynak-Wasowicz, U | 1 |
| Sładek, M | 1 |
| Pieczarkowski, S | 1 |
| Adamski, P | 1 |
| Kochan, P | 1 |
| Heczko, PB | 1 |
| Bachmann, O | 1 |
| Seidler, U | 1 |
| Cario, E | 1 |
| Castagliuolo, I | 1 |
| Galeazzi, F | 1 |
| Ferrari, S | 1 |
| Elli, M | 1 |
| Brun, P | 1 |
| Cavaggioni, A | 1 |
| Tormen, D | 1 |
| Sturniolo, GC | 1 |
| Morelli, L | 1 |
| Palù, G | 1 |
| Zhang, L | 1 |
| Mitchell, H | 1 |
| Fargeas, MJ | 1 |
| Theodorou, V | 1 |
| More, J | 1 |
| Wal, JM | 1 |
| Fioramonti, J | 1 |
| Bueno, L | 1 |
| Ryder, SD | 2 |
| Parker, N | 2 |
| Ecclestone, D | 1 |
| Haqqani, MT | 1 |
| Rhodes, JM | 2 |
| Raouf, AH | 1 |
| Walker, RJ | 1 |
| Schultsz, C | 1 |
| Van Den Berg, FM | 1 |
| Ten Kate, FW | 1 |
| Tytgat, GN | 1 |
| Dankert, J | 1 |
| Halm, DR | 1 |
| Halm, ST | 1 |
17 reviews available for guaifenesin and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Gut Microbiota and Dietary Factors as Modulators of the Mucus Layer in Inflammatory Bowel Disease.
Topics: Animals; Diet; Gastrointestinal Microbiome; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; | 2021 |
The Impact of MicroRNAs during Inflammatory Bowel Disease: Effects on the Mucus Layer and Intercellular Junctions for Gut Permeability.
Topics: Animals; Gastrointestinal Tract; Humans; Inflammatory Bowel Diseases; Intercellular Junctions; Micro | 2021 |
Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems.
Topics: Administration, Oral; Drug Delivery Systems; Gastrointestinal Agents; Humans; Hydrogen-Ion Concentra | 2022 |
Emerging role of colorectal mucus in gastroenterology diagnostics.
Topics: Biomarkers; Colonoscopy; Colorectal Neoplasms; Feces; Gastroenterology; Humans; Inflammatory Bowel D | 2022 |
Intestinal mucus components and secretion mechanisms: what we do and do not know.
Topics: Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Mucus | 2023 |
Mucus barrier, mucins and gut microbiota: the expected slimy partners?
Topics: Diet; Gastrointestinal Microbiome; Gastrointestinal Tract; Host Microbial Interactions; Humans; Infl | 2020 |
Layered defense: how mucus and tight junctions seal the intestinal barrier.
Topics: Animals; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Mucins; Mucus; Permeability; Tight | 2017 |
Clinical importance of IL-22 cascade in IBD.
Topics: Gastrointestinal Agents; Genetic Predisposition to Disease; Humans; Immunity, Mucosal; Inflammatory | 2018 |
Frontline defenders: goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and disease.
Topics: Animals; Bacteria; Bacterial Infections; Gastrointestinal Microbiome; Goblet Cells; Homeostasis; Hos | 2018 |
Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology.
Topics: Animals; Antimicrobial Cationic Peptides; Bacteria; Colorectal Neoplasms; Dietary Fiber; Epithelial | 2013 |
Defective antibacterial barrier in inflammatory bowel disease.
Topics: alpha-Defensins; Animals; Antimicrobial Cationic Peptides; beta-Defensins; Humans; Inflammatory Bowe | 2013 |
The role of glycosylation in IBD.
Topics: Animals; Galactose; Glycosylation; Humans; Immunoglobulin G; Inflammatory Bowel Diseases; Intestinal | 2014 |
Mucus layers in inflammatory bowel disease.
Topics: Animals; Humans; Inflammatory Bowel Diseases; Mucous Membrane; Mucus | 2014 |
Intestinal barrier homeostasis in inflammatory bowel disease.
Topics: Biomarkers; Enteroendocrine Cells; Homeostasis; Humans; Inflammatory Bowel Diseases; Intestinal Muco | 2015 |
News from the end of the gut--how the highly segmental pattern of colonic HCO₃⁻ transport relates to absorptive function and mucosal integrity.
Topics: Animals; Bicarbonates; Chloride-Bicarbonate Antiporters; Colon; Fatty Acids, Volatile; Humans; Infla | 2011 |
Commensal-innate immune miscommunication in IBD pathogenesis.
Topics: Bacteria; Cell Transformation, Neoplastic; Epithelium; Humans; Immunity; Inflammatory Bowel Diseases | 2012 |
The roles of mucus-associated bacteria in inflammatory bowel disease.
Topics: Adult; Animals; Disease Models, Animal; Helicobacter; Humans; Inflammatory Bowel Diseases; Mucus | 2006 |
28 other studies available for guaifenesin and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Dietary xylo-oligosaccharide ameliorates colonic mucus microbiota penetration with restored autophagy in interleukin-10 gene-deficient mice.
Topics: Animals; Autophagy; Colitis; Inflammatory Bowel Diseases; Interleukin-10; Male; Mice; Microbiota; Mu | 2022 |
Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.
Topics: Animals; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Colitis; Colon; | 2021 |
Mucus sialylation determines intestinal host-commensal homeostasis.
Topics: Animals; Gastrointestinal Microbiome; Homeostasis; Humans; Inflammatory Bowel Diseases; Intestinal M | 2022 |
Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway.
Topics: Animals; Apoptosis; Colitis; Estrogen Receptor beta; Furans; Goblet Cells; Inflammatory Bowel Diseas | 2022 |
Milk Fat Globule Membrane Attenuates Acute Colitis and Secondary Liver Injury by Improving the Mucus Barrier and Regulating the Gut Microbiota.
Topics: Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Glycolipids; | 2022 |
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.
Topics: Animals; Colon; Gastrointestinal Microbiome; Goblet Cells; Inflammasomes; Inflammatory Bowel Disease | 2019 |
The expression of P2Y
Topics: Animals; Colitis; Dextran Sulfate; Gene Expression Regulation; Goblet Cells; Humans; Inflammatory Bo | 2021 |
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
Topics: Amino Acid Sequence; Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Endoplasmi | 2021 |
A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Bacteroides fragilis; Colorect | 2017 |
Mucus protectors: Promising therapeutic strategies for inflammatory bowel disease.
Topics: Animals; Cytokines; Enzymes; Gastrointestinal Microbiome; Glycoside Hydrolases; Humans; Hydrogen-Ion | 2018 |
Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents; Budesonide; Colon; Drug Compounding; Drug Delivery Systems; Enema | 2018 |
Akkermansia muciniphila strain ATCC BAA-835 does not promote short-term intestinal inflammation in gnotobiotic interleukin-10-deficient mice.
Topics: Animals; Body Weight; Cecum; Disease Models, Animal; Escherichia coli; Gastrointestinal Microbiome; | 2019 |
Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial
Topics: Acids; Animals; Autophagy; Bacterial Proteins; Dextran Sulfate; Dinoprostone; Disease Models, Animal | 2019 |
A 3-D artificial colon tissue mimic for the evaluation of nanoparticle-based drug delivery system.
Topics: Animals; Biomimetics; Caco-2 Cells; Colitis; Colon; Cytokines; Drug Delivery Systems; Drug Evaluatio | 2014 |
A two-stage statistical procedure for feature selection and comparison in functional analysis of metagenomes.
Topics: Case-Control Studies; Data Interpretation, Statistical; Gastrointestinal Tract; Gene Expression Regu | 2015 |
Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier.
Topics: Animals; Citrobacter rodentium; Cysteine; Epithelial Cells; Escherichia coli; Gastrointestinal Micro | 2015 |
Assessment of cytology and mucin 2 in colorectal mucus collected from patients with inflammatory bowel disease: Results of a pilot trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Colon; Cytological Techniques; Feasibility S | 2016 |
A glance at … dietary emulsifiers, the human intestinal mucus and microbiome, and dietary fiber.
Topics: Bacterial Translocation; Dietary Fiber; Emulsifying Agents; Food Additives; Gastrointestinal Microbi | 2016 |
Damage of the Mucus Layer: The Possible Shared Critical Common Cause for Both Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS).
Topics: Humans; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Mucus | 2017 |
Intestinal mucus barrier in normal and inflamed colon.
Topics: Bacteria; Bacterial Physiological Phenomena; Biofilms; Colon; Humans; Inflammatory Bowel Diseases; I | 2009 |
Mucosal bacterial microflora and mucus layer thickness in adolescents with inflammatory bowel disease.
Topics: Adolescent; Bacteria; Biopsy; Case-Control Studies; Child; Colonoscopy; Colony Count, Microbial; Fem | 2009 |
Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.
Topics: Animals; Bacterial Adhesion; Dextran Sulfate; Disease Models, Animal; Feces; Inflammatory Bowel Dise | 2005 |
Synergic effect of bacterial glycosidases and digestive proteases on mucus degradation and the reduced risk of inflammatory bowel disease-like gut damage in both germ-free and poor hygiene conditions.
Topics: Bacterial Proteins; Glycoside Hydrolases; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Mu | 2008 |
Boosted systemic immune and local responsiveness after intestinal inflammation in orally sensitized guinea pigs.
Topics: Analysis of Variance; Animals; Cell Membrane Permeability; Colon; Edetic Acid; Guinea Pigs; Histamin | 1995 |
Peanut lectin stimulates proliferation in colonic explants from patients with inflammatory bowel disease and colon polyps.
Topics: Acetylglucosamine; Adolescent; Adult; Aged; Cell Division; Colon; Colonic Polyps; Culture Techniques | 1994 |
Abnormal mucosal glycoprotein synthesis in inflammatory bowel diseases is not related to cigarette smoking.
Topics: Acetylglucosamine; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Biopsy; Colonos | 1995 |
The intestinal mucus layer from patients with inflammatory bowel disease harbors high numbers of bacteria compared with controls.
Topics: Bacteria; Biopsy; Colon; Colony Count, Microbial; Humans; Ileum; In Situ Hybridization; Inflammatory | 1999 |
Secretagogue response of goblet cells and columnar cells in human colonic crypts.
Topics: Adenosine; Biological Transport; Body Fluids; Carbachol; Cell Size; Cholecystokinin; Cholinergic Ago | 2000 |