guaifenesin has been researched along with Apnea, Obstructive Sleep in 4 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raff, H | 1 |
| Ettema, SL | 1 |
| Eastwood, DC | 1 |
| Woodson, BT | 1 |
| Wan, N | 1 |
| Tang, X | 1 |
| Ding, H | 1 |
| Yan, Y | 1 |
| Zhuang, Y | 1 |
| Qi, C | 1 |
| Chen, Q | 1 |
| Xie, W | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Liang, M | 1 |
| Ning, W | 1 |
| Cao, J | 1 |
| Winther, B | 1 |
| Gross, BC | 1 |
| Hendley, JO | 1 |
| Early, SV | 1 |
| Schmidt, HJ | 1 |
| Bhandari, V | 1 |
| Bhandari, A | 1 |
| Davies, J | 1 |
| Marshall, BC | 1 |
| Praud, JP | 1 |
| Zar, HJ | 1 |
| Rubin, BK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea[NCT01196117] | 18 participants (Actual) | Interventional | 2004-11-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Epworth Sleepiness Score (ESS) is a scale to assess sleepiness during waking hours. The scale ranges from 0-24 with higher scores indicative of greater sleepiness. (NCT01196117)
Timeframe: Difference between Baseline(Day 0) and Average of Day 1,7,14.
| Intervention | units on a scale (Median) |
|---|---|
| 14 Days of Placebo Therapy, Then CPAP | 10.7 |
| 14 Days of CPAP Therapy | 8.9 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 7, 7am
| Intervention | nmol/l (Mean) |
|---|---|
| CPAP>= 3 Hours Per Night | 9.9 |
| CPAP<3 Hours Per Night | 13.3 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 0, 11pm
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 3.2 |
| CPAP<3 Hours Per Night | 1.2 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 1, 11pm
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 2.2 |
| CPAP<3 Hours Per Night | 1.8 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 14, 11pm
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 1.9 |
| CPAP<3 Hours Per Night | 2.2 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 7, 11pm
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 3.0 |
| CPAP<3 Hours Per Night | 2.5 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 0, 7am
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 12.5 |
| CPAP<3 Hours Per Night | 12.1 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 1, 7am
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 7.4 |
| CPAP<3 Hours Per Night | 13.6 |
Salivary Cortisol was measured by enzyme-linked immunosorbent assay. The reference range for healthy adults is <4.2 nmol/l. (NCT01196117)
Timeframe: Day 14, 7am
| Intervention | nmol/l (Median) |
|---|---|
| CPAP>= 3 Hours Per Night | 9.2 |
| CPAP<3 Hours Per Night | 15.0 |
1 review available for guaifenesin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
The future in paediatric respirology.
Topics: Adult; Asthma; Bronchopulmonary Dysplasia; Child; Chronic Disease; Cystic Fibrosis; Humans; Infant, | 2010 |
1 trial available for guaifenesin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Salivary cortisol in obstructive sleep apnea: the effect of CPAP.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Continuous Positive Airway Pressure; Expecto | 2011 |
2 other studies available for guaifenesin and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Influence of coexistence of mild OSA on airway mucus hypersecretion in patients with COPD.
Topics: Breath Tests; Epithelial Cells; Humans; Mucus; Pulmonary Disease, Chronic Obstructive; Sleep Apnea, | 2021 |
Location of bacterial biofilm in the mucus overlying the adenoid by light microscopy.
Topics: Adenoids; Bacteria; Biofilms; Child; Chronic Disease; Coloring Agents; Humans; In Situ Hybridization | 2009 |