guaifenesin and Alveolitis, Fibrosing
guaifenesin has been researched along with Alveolitis, Fibrosing in 32 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Montelukast, a leukotriene receptor antagonist, is used commercially as a maintenance treatment for asthma and to relieve allergic symptoms." | 7.79 | Effects of montelukast on subepithelial/peribronchial fibrosis in a murine model of ovalbumin induced chronic asthma. ( Jeon, WY; Lee, MY; Shin, HK; Shin, IS, 2013) |
| "treatment." | 3.83 | Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airway mucus and bleomycin-\ induced pulmonary fibrosis in rats. ( Choong, JL; Hyo-Seok, S; Hyun, JL, 2016) |
| "Montelukast, a leukotriene receptor antagonist, is used commercially as a maintenance treatment for asthma and to relieve allergic symptoms." | 3.79 | Effects of montelukast on subepithelial/peribronchial fibrosis in a murine model of ovalbumin induced chronic asthma. ( Jeon, WY; Lee, MY; Shin, HK; Shin, IS, 2013) |
| "Asthma, chronic obstructive pulmonary disease, and cystic fibrosis are three chronic pulmonary diseases that affect an estimated 420 million individuals across the globe." | 2.58 | Epigenetics of Mucus Hypersecretion in Chronic Respiratory Diseases. ( Breitzig, MT; Kolliputi, N; Lockey, RF; Saco, TV, 2018) |
| "Chronic obstructive pulmonary disease (COPD) is characterized and defined by limitation of expiratory airflow." | 2.43 | Pathogenesis of COPD. ( Rennard, SI; Spurzem, JR, 2005) |
| "Interestingly, pulmonary fibrosis observed in wild-type mice under the chronic protocol was completely absent in iNOS(-/-) mice despite persistent IL-5 and IL-13 production, suggesting that these cytokines were insufficient for pulmonary fibrosis." | 1.36 | Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation. ( Abd Elmageed, ZY; Boulares, AH; Errami, Y; Hans, CP; Ju, J; Kim, H; Naura, AS; Ochoa, AC; Park, J; Rodriguez, PC; Zerfaoui, M, 2010) |
| " In the present study, we have investigated the effect of a therapeutic dosing regimen with an anti-IL-13 monoclonal antibody (mAb) in a chronic mouse model of persistent asthma." | 1.33 | Therapeutic dosing with anti-interleukin-13 monoclonal antibody inhibits asthma progression in mice. ( Bugelski, PJ; Das, AM; Emmell, E; Giles-Komar, J; Griswold, DE; Lakshminarayanan, M; Li, L; Petley, T; Rafferty, P; Volk, A; Yang, G, 2005) |
| "Five idiopathic pulmonary fibrosis (IPF) patients with sputum since the initial period of the disease (IPF SP+, more than 15 ml/day) were compared with five IPF patients without sputum throughout the course of the disease (IPF SP-) and four control subjects without pulmonary disease matched for age and sex." | 1.28 | Morphometric analysis of airways in idiopathic pulmonary fibrosis patients with mucous hypersecretion. ( Aikawa, T; Andoh, Y; Sasaki, H; Shimura, S; Takishima, T, 1992) |
Research
Studies (32)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (34.38) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 11 (34.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| HEISEN, AJ | 1 |
| Saco, TV | 1 |
| Breitzig, MT | 1 |
| Lockey, RF | 1 |
| Kolliputi, N | 1 |
| Hyo-Seok, S | 1 |
| Hyun, JL | 1 |
| Choong, JL | 1 |
| Shin, IS | 1 |
| Jeon, WY | 1 |
| Shin, HK | 1 |
| Lee, MY | 1 |
| Pusterla, N | 1 |
| Magdesian, KG | 1 |
| Mapes, SM | 1 |
| Zavodovskaya, R | 1 |
| Kass, PH | 1 |
| Franchini, ML | 1 |
| Athanazio, R | 1 |
| Amato-Lourenço, LF | 1 |
| Carreirão-Neto, W | 1 |
| Saldiva, PH | 1 |
| Lorenzi-Filho, G | 1 |
| Rubin, BK | 1 |
| Nakagawa, NK | 1 |
| Chen, J | 1 |
| Yang, X | 1 |
| Zhang, W | 1 |
| Peng, D | 1 |
| Xia, Y | 1 |
| Lu, Y | 1 |
| Han, X | 1 |
| Song, G | 1 |
| Zhu, J | 1 |
| Liu, R | 1 |
| Alcorn, JF | 1 |
| van der Velden, J | 1 |
| Brown, AL | 1 |
| McElhinney, B | 1 |
| Irvin, CG | 1 |
| Janssen-Heininger, YM | 1 |
| Oh, SY | 1 |
| Zheng, T | 2 |
| Kim, YK | 1 |
| Cohn, L | 1 |
| Homer, RJ | 4 |
| McKenzie, AN | 1 |
| Zhu, Z | 3 |
| Ramaprakash, H | 1 |
| Hogaboam, CM | 1 |
| Halwani, R | 1 |
| Al-Muhsen, S | 1 |
| Al-Jahdali, H | 1 |
| Hamid, Q | 1 |
| Naura, AS | 1 |
| Zerfaoui, M | 1 |
| Kim, H | 1 |
| Abd Elmageed, ZY | 1 |
| Rodriguez, PC | 1 |
| Hans, CP | 1 |
| Ju, J | 1 |
| Errami, Y | 1 |
| Park, J | 1 |
| Ochoa, AC | 1 |
| Boulares, AH | 1 |
| van Echteld, CJ | 1 |
| Beckmann, N | 1 |
| Cho, JY | 1 |
| Pham, A | 1 |
| Rosenthal, P | 1 |
| Miller, M | 1 |
| Doherty, T | 1 |
| Broide, DH | 1 |
| POLGAR, G | 1 |
| DENTON, R | 1 |
| Yang, G | 1 |
| Li, L | 1 |
| Volk, A | 1 |
| Emmell, E | 1 |
| Petley, T | 1 |
| Giles-Komar, J | 1 |
| Rafferty, P | 1 |
| Lakshminarayanan, M | 1 |
| Griswold, DE | 1 |
| Bugelski, PJ | 1 |
| Das, AM | 1 |
| Spurzem, JR | 1 |
| Rennard, SI | 1 |
| Muz, MH | 1 |
| Deveci, F | 1 |
| Bulut, Y | 1 |
| Ilhan, N | 1 |
| Yekeler, H | 1 |
| Turgut, T | 1 |
| Chapoval, SP | 1 |
| Al-Garawi, A | 1 |
| Lora, JM | 1 |
| Strickland, I | 1 |
| Ma, B | 2 |
| Lee, PJ | 1 |
| Ghosh, S | 1 |
| Coyle, AJ | 1 |
| Elias, JA | 3 |
| Lewis, JF | 1 |
| Edwards, CW | 1 |
| Carlile, A | 1 |
| Cockrill, BA | 1 |
| Hales, CA | 1 |
| Wang, Z | 1 |
| Chen, Q | 1 |
| Geba, GP | 1 |
| Wang, J | 1 |
| Zhang, Y | 1 |
| Lee, CG | 1 |
| Charo, IF | 1 |
| Noble, P | 1 |
| Bouton, C | 1 |
| Herson, S | 1 |
| Huchon, G | 1 |
| Akoun, G | 1 |
| Andoh, Y | 1 |
| Aikawa, T | 1 |
| Shimura, S | 1 |
| Sasaki, H | 1 |
| Takishima, T | 1 |
| Isawa, T | 1 |
| Teshima, T | 1 |
| Hirano, T | 1 |
| Ebina, A | 1 |
| Konno, K | 1 |
| Gent, M | 1 |
| Knowlson, PA | 1 |
| Rime, FJ | 1 |
| Benda, R | 1 |
| Fuchsova, M | 1 |
| Hronovský, V | 1 |
| Dunnill, MS | 1 |
| Ryder, RC | 1 |
| Lyons, JP | 1 |
| Campbell, H | 1 |
| Gough, J | 1 |
| Ulmer, WT | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy as Well as Stand-alone Therapy in Patients With Respiratory Insufficiency[NCT03081650] | 30 participants (Anticipated) | Interventional | 2016-08-16 | Recruiting | |||
| Effects of Long-term Dry and Humidified Low-flow Oxygen Via Nasal Cannula on Nasal Mucociliary Clearance, Mucus Properties, Inflammation and Airway Symptoms in Patients[NCT02515786] | Phase 1/Phase 2 | 19 participants (Anticipated) | Interventional | 2013-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
6 reviews available for guaifenesin and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Epigenetics of Mucus Hypersecretion in Chronic Respiratory Diseases.
Topics: Asthma; Cystic Fibrosis; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone C | 2018 |
Role of transforming growth factor-β in airway remodeling in asthma.
Topics: Airway Remodeling; Animals; Asthma; Eosinophils; Goblet Cells; Humans; Inflammation Mediators; Lung; | 2011 |
A view on imaging in drug research and development for respiratory diseases.
Topics: Animals; Clinical Trials as Topic; Diagnostic Imaging; Disease Models, Animal; Drug Delivery Systems | 2011 |
Pathogenesis of COPD.
Topics: Airway Resistance; Apoptosis; Cytokines; Environmental Pollutants; Female; Humans; Male; Mucus; Prog | 2005 |
Allergic bronchopulmonary aspergillosis.
Topics: Administration, Oral; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Asthma; Bronc | 1999 |
[Bronchiolo-alveolar cancer].
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adolescent; Adult; Bronchi; Female; Humans; Lung; Lung Neoplasm | 1976 |
Trials
2 trials available for guaifenesin and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function.
Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac | 2016 |
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function.
Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac | 2016 |
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function.
Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac | 2016 |
Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function.
Topics: Aged; Aged, 80 and over; Bronchiectasis; Cough; Cytokines; Disease Progression; Epidermal Growth Fac | 2016 |
Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases.
Topics: Adult; Airway Resistance; Aniline Compounds; Asthma; Chronic Disease; Clinical Trials as Topic; Fema | 1969 |
Other Studies
24 other studies available for guaifenesin and Alveolitis, Fibrosing
| Article | Year |
|---|---|
TREATMENT OF BRONCHIAL AND PULMONARY PARENCHYMAL DISORDERS.
Topics: Asthma; Bronchitis; Geriatrics; Guaifenesin; Humans; Lung Diseases; Pulmonary Emphysema; Pulmonary F | 1964 |
Pyunkang-hwan (Pyunkang-Tang) ameliorates air pollutant-induced inflammatory hypersecretion of airway mucus and bleomycin-\
induced pulmonary fibrosis in rats.
Topics: Air Pollutants; Animals; Bleomycin; Collagen; Drugs, Chinese Herbal; Humans; Hydroxyproline; Lung; M | 2016 |
Effects of montelukast on subepithelial/peribronchial fibrosis in a murine model of ovalbumin induced chronic asthma.
Topics: Acetates; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cycloprop | 2013 |
Assessment of quantitative polymerase chain reaction for equine herpesvirus-5 in blood, nasal secretions and bronchoalveolar lavage fluid for the laboratory diagnosis of equine multinodular pulmonary fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Herpesviridae Infections; Horse Diseases; Horses; Mucus; Poly | 2017 |
Therapeutic Effects of Resveratrol in a Mouse Model of LPS and Cigarette Smoke-Induced COPD.
Topics: Animals; Beclin-1; Bronchoalveolar Lavage Fluid; Cytokines; Lipopolysaccharides; Lung; Mice; Mucus; | 2016 |
c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis.
Topics: Animals; Antigens; Bleomycin; Collagen; Enzyme Activation; Epithelium; Gene Expression Regulation; I | 2009 |
A critical role of SHP-1 in regulation of type 2 inflammation in the lung.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Epithelium; Hypertrophy | 2009 |
Intranasal CpG therapy attenuated experimental fungal asthma in a TLR9-dependent and -independent manner.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Aspergillus fumigatus; Asthma; Bronchia | 2010 |
Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation.
Topics: Acute Disease; Allergens; Animals; Cells, Cultured; Chickens; Eosinophilia; Gene Deletion; Inflammat | 2010 |
Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchi; Collagen; Eosinophils; Extracellular Matrix | 2011 |
Cystic fibrosis in adults. Studies of pulmonary function and some physical properties of bronchial mucus.
Topics: Adult; Cystic Fibrosis; Humans; Lung; Mucus; Pulmonary Fibrosis; Respiration | 1962 |
Therapeutic dosing with anti-interleukin-13 monoclonal antibody inhibits asthma progression in mice.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Ch | 2005 |
The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model.
Topics: Acetates; Airway Obstruction; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Cyclopropanes; Cyste | 2006 |
Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
Topics: Adenoviridae; Animals; Apoptosis; Caspases; Heterocyclic Compounds, 3-Ring; I-kappa B Kinase; Inflam | 2007 |
Fatal bronchial asthma in children: report of three cases.
Topics: Asthma; Bronchi; Child, Preschool; Death; Female; Humans; Male; Mucus; Pulmonary Emphysema; Pulmonar | 1967 |
The larger bronchi in cryptogenic fibrosing alveolitis: a morphometric study.
Topics: Adult; Aged; Bronchi; Bronchitis; Exocrine Glands; Female; Humans; Hypertrophy; Male; Middle Aged; M | 1982 |
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
Topics: Airway Resistance; Animals; Asthma; Bronchi; Bronchoconstrictor Agents; Chemokine CCL11; Chemokines, | 1999 |
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemokine CCL2; Chemokines, CC; Endopeptidas | 2002 |
Morphometric analysis of airways in idiopathic pulmonary fibrosis patients with mucous hypersecretion.
Topics: Aged; Bronchi; Eosinophils; Exocrine Glands; Female; Humans; Lung; Lymphocytes; Macrophages; Male; M | 1992 |
Mucociliary clearance mechanism in interstitial lung disease.
Topics: Aerosols; Cilia; Humans; Lung; Methods; Mucus; Pulmonary Fibrosis; Radionuclide Imaging; Sarcoidosis | 1986 |
Course of air-borne infection cause by B virus (Herpesvirus simiae) II. Distribution of B virus in the organism of rabbits and histopathological changes in the organs.
Topics: Adrenal Glands; Aerosols; Animals; Blood; Central Nervous System; Heart; Herpesviridae Infections; I | 1969 |
The contribution of morphology to the study of chronic obstructive lung disease.
Topics: Adult; Age Factors; Aged; Airway Obstruction; Biopsy; Bronchi; Bronchitis; Cilia; Exudates and Trans | 1974 |
Bronchial mucous gland status in coal workers' pneumoconiosis.
Topics: Age Factors; Aged; Autopsy; Bronchi; Coal Mining; Humans; Lung; Male; Middle Aged; Mucus; Pneumoconi | 1972 |
Emphysema of the lung: clinical and experimental investigations of its pathogenesis.
Topics: Humans; Mucus; Pleura; Pressure; Pulmonary Emphysema; Pulmonary Fibrosis; Radiography; Respiration; | 1970 |