Page last updated: 2024-10-28

guaifenesin and Allergic Rhinitis

guaifenesin has been researched along with Allergic Rhinitis in 21 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

ExcerptRelevanceReference
"Formononetin has proven to be anti‑inflammatory and able to alleviate symptoms of certain allergic diseases."5.62Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway. ( Chen, X; Huang, J; Xie, A, 2021)
"Ursolic acid (UA) has activities in immune regulation and anti-inflammatory."5.62Ursolic Acid Alleviates Mucus Secretion and Tissue Remodeling in Rat Model of Allergic Rhinitis After PM2.5 Exposure. ( Deng, C; Dong, W; Duan, Y; Guo, Z; Han, Z; Sun, N; Wang, H; Zhang, R; Zhao, Q; Zhuang, G, 2021)
"Compared with IL 33 group, the inflammatory cell infiltration around the trachea and blood vessels of the lung tissue in the IL 33+ Iloprost group were reduced; goblet cell hyperplasia was observed in airway mucosa of IL 33 group, and the mucus secretion increased; the percentage of EOS and ILC2s in the BALF and lung single cell suspensions in IL 33+ Iloprost group were statistically lower than that of IL 33 group (p < 0."3.96Iloprost inhibits acute allergic nasal inflammation by GATA3 -ILC2 pathway in mice. ( Jiang, X; Li, L; Liu, H; Liu, J; Liu, K; Yang, C; Zhang, X, 2020)
"Formononetin has proven to be anti‑inflammatory and able to alleviate symptoms of certain allergic diseases."1.62Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway. ( Chen, X; Huang, J; Xie, A, 2021)
"Ursolic acid (UA) has activities in immune regulation and anti-inflammatory."1.62Ursolic Acid Alleviates Mucus Secretion and Tissue Remodeling in Rat Model of Allergic Rhinitis After PM2.5 Exposure. ( Deng, C; Dong, W; Duan, Y; Guo, Z; Han, Z; Sun, N; Wang, H; Zhang, R; Zhao, Q; Zhuang, G, 2021)
"Histamine is an important mediator of allergic reactions, and mucus hypersecretion is a major allergic symptom."1.46Synergistic mucus secretion by histamine and IL-4 through TMEM16A in airway epithelium. ( Cho, HJ; Choi, JY; Kang, JW; Kang, MJ; Kim, CH; Lee, HJ; Lee, SN; Lee, YH; Min, HJ; Namkung, W; Oh, R; Yoon, JH, 2017)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (42.86)24.3611
2020's12 (57.14)2.80

Authors

AuthorsStudies
Huang, J1
Chen, X1
Xie, A1
Yen, TT1
Jiang, RS1
Chang, CY1
Wu, CY1
Liang, KL1
Xu, H1
Wang, L1
Chen, H1
Cai, H1
Liu, J1
Jiang, X1
Li, L1
Liu, H1
Zhang, X1
Liu, K1
Yang, C1
Zhu, YM1
Wu, F1
Zhou, JY1
Cavalcanti, RFP1
Gadelha, FAAF1
de Jesus, TG1
Cavalcante-Silva, LHA1
Paiva Ferreira, LKD2
Paiva Ferreira, LAM1
Vieira, GC1
Piuvezam, MR2
Sun, N1
Deng, C1
Zhao, Q1
Han, Z1
Guo, Z1
Wang, H2
Dong, W1
Duan, Y1
Zhuang, G1
Zhang, R2
Jeon, YJ1
Gil, CH1
Won, J1
Jo, A1
Kim, HJ1
Bezerra Barros, GC1
Ferreira, LAMP1
Mozzini Monteiro, T1
Alves, AF1
Pereira, RA1
Wang, T1
Wang, P1
Chen, D1
Xu, Z1
Yang, L1
Gao, W1
Jin, Z1
Zheng, Y1
Xu, Y1
Kang, JW1
Lee, YH1
Kang, MJ1
Lee, HJ1
Oh, R1
Min, HJ1
Namkung, W1
Choi, JY1
Lee, SN1
Kim, CH1
Yoon, JH1
Cho, HJ1
Ismail, NFF1
Neoh, CF1
Lim, SM1
Abdullah, AH1
Mastuki, MF1
Ramasamy, K1
Zainuddin, N1
Saim, L1
Ming, LC1
Meng, Y1
Lou, H1
Wang, Y1
Wang, C1
Zhang, L1
Gao, Y1
Yu, Z1
Yue, L1
Yin, X1
Hao, F1
Dong, J1
Ren, X1
Xu, O1
Shan, C1
Gröger, M1
Bernt, A1
Wolf, M1
Mack, B1
Pfrogner, E1
Becker, S1
Kramer, MF1
Ponikau, JU1
Winter, LA1
Kephart, GM1
Squillace, DL1
Hershcovitch, MD1
Moon, S1
Sherris, DA1
Kern, EB1
Gleich, GJ1
Kita, H1
Teng, Y1
Liu, C1
Zhou, L1
Zhuang, W1
Huang, Y1
Hong, Z1
Kumar, MS1
Panella, NJ1
Magliocca, KR1
Vivas, EX1
Shah, SA1
Ishinaga, H1
Hou, B1
Okano, M1
Takeuchi, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation[NCT03673384]50 participants (Actual)Interventional2015-03-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for guaifenesin and Allergic Rhinitis

ArticleYear
The immediate effect of facial candling on inflammatory mediators, substance P, symptoms severity, and quality of life in allergic rhinitis patients: Study protocol for a randomized controlled trial.
    Medicine, 2017, Volume: 96, Issue:30

    Topics: Academic Medical Centers; Adolescent; Adult; Aged; Biomarkers; Humans; Malaysia; Medicine, East Asia

2017

Other Studies

20 other studies available for guaifenesin and Allergic Rhinitis

ArticleYear
Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway.
    Molecular medicine reports, 2021, Volume: 24, Issue:6

    Topics: Anti-Inflammatory Agents; Cytokines; Epithelial Cells; Humans; Inflammation; Interleukin-13; Isoflav

2021
Erythromycin reduces nasal inflammation by inhibiting immunoglobulin production, attenuating mucus secretion, and modulating cytokine expression.
    Scientific reports, 2021, 11-05, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chronic Di

2021
HDAC4 depletion ameliorates IL-13-triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF-κB signaling.
    Immunity, inflammation and disease, 2022, Volume: 10, Issue:11

    Topics: Epithelial Cells; Histamine; Histone Deacetylases; Humans; Immunoglobulin E; Interleukin-13; Mucus;

2022
Iloprost inhibits acute allergic nasal inflammation by GATA3 -ILC2 pathway in mice.
    Respiratory physiology & neurobiology, 2020, Volume: 276

    Topics: Animals; Disease Models, Animal; Female; GATA3 Transcription Factor; Goblet Cells; Hyperplasia; Ilop

2020
Analysis the effect of miR-141-3p/HMGB1 in LPS-induced mucus production and the apoptosis in nasal epithelial cells.
    The Kaohsiung journal of medical sciences, 2020, Volume: 36, Issue:8

    Topics: Animals; Apoptosis; Base Sequence; Down-Regulation; Epithelial Cells; Gene Silencing; HMGB1 Protein;

2020
Warifteine and methylwarifteine inhibited the type 2 immune response on combined allergic rhinitis and asthma syndrome (CARAS) experimental model through NF-кB pathway.
    International immunopharmacology, 2020, Volume: 85

    Topics: Alkaloids; Animals; Anti-Allergic Agents; Asthma; Behavior, Animal; Bronchoalveolar Lavage Fluid; Ci

2020
Ursolic Acid Alleviates Mucus Secretion and Tissue Remodeling in Rat Model of Allergic Rhinitis After PM2.5 Exposure.
    American journal of rhinology & allergy, 2021, Volume: 35, Issue:2

    Topics: Animals; Disease Models, Animal; Mucus; Nasal Mucosa; Ovalbumin; Particulate Matter; Rats; Rhinitis,

2021
Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa.
    BMC microbiology, 2020, 10-07, Volume: 20, Issue:1

    Topics: Animals; Corynebacterium; Cytokines; Disease Models, Animal; Enterobacter aerogenes; Epithelial Cell

2020
4-Carvomenthenol ameliorates the murine combined allergic rhinitis and asthma syndrome by inhibiting IL-13 and mucus production via p38MAPK/NF-κB signaling pathway axis.
    International immunopharmacology, 2020, Volume: 88

    Topics: Allergens; Animals; Anti-Allergic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Female; I

2020
circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis.
    Molecular medicine reports, 2021, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Apoptosis; Arrestins; Cell Survival; Cells, Cultured; Chemokine CCL11; Cytokines;

2021
Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN.
    Molecular medicine reports, 2021, Volume: 24, Issue:3

    Topics: Cell Line; Chemokine CCL11; Cytokines; Epithelial Cells; Ficusin; Granulocyte-Macrophage Colony-Stim

2021
Synergistic mucus secretion by histamine and IL-4 through TMEM16A in airway epithelium.
    American journal of physiology. Lung cellular and molecular physiology, 2017, Sep-01, Volume: 313, Issue:3

    Topics: Adult; Animals; Anoctamin-1; Cells, Cultured; Chloride Channels; Epithelial Cells; Gene Expression R

2017
The use of specific immunoglobulin E in nasal secretions for the diagnosis of allergic rhinitis.
    The Laryngoscope, 2018, Volume: 128, Issue:9

    Topics: Adolescent; Adult; Allergens; Animals; Artemisia; Female; Humans; Immunoglobulin E; Male; Middle Age

2018
MicroRNA‑16 inhibits interleukin‑13‑induced inflammatory cytokine secretion and mucus production in nasal epithelial cells by suppressing the IκB kinase β/nuclear factor‑κB pathway.
    Molecular medicine reports, 2018, Volume: 18, Issue:4

    Topics: Base Sequence; Down-Regulation; Epithelial Cells; Humans; I-kappa B Kinase; Inflammation; Inflammati

2018
Long Noncoding RNA Linc00632 Inhibits Interleukin-13-Induced Inflammatory Cytokine and Mucus Production in Nasal Epithelial Cells.
    Journal of innate immunity, 2020, Volume: 12, Issue:1

    Topics: Cells, Cultured; Chemokine CCL11; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor;

2020
Eosinophils and mast cells: a comparison of nasal mucosa histology and cytology to markers in nasal discharge in patients with chronic sino-nasal diseases.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Chronic Disease; Eosin

2013
An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein.
    International forum of allergy & rhinology, 2015, Volume: 5, Issue:1

    Topics: Biomarkers; Cell Degranulation; Cell Movement; Chronic Disease; Diagnosis, Differential; Enzyme-Link

2015
miR-143 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients by targeting IL13Rα1.
    Biochemical and biophysical research communications, 2015, Jan-30, Volume: 457, Issue:1

    Topics: Adult; Chemokine CCL11; Down-Regulation; Epithelial Cells; Female; Granulocyte-Macrophage Colony-Sti

2015
Otopolyposis With Middle Ear Allergic Mucin in a Patient With Allergic Fungal Rhinosinusitis.
    The Annals of otology, rhinology, and laryngology, 2016, Volume: 125, Issue:10

    Topics: Adult; Ear Diseases; Ear, Middle; Female; Humans; Mucins; Mucus; Mycoses; Polyps; Rhinitis, Allergic

2016
Effects of interleukin-31 on MUC5AC gene expression in nasal allergic inflammation.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: Cell Line; Cell Line, Tumor; Gene Expression Regulation; Humans; Interleukins; Mucin 5AC; Mucus; Nas

2013