Page last updated: 2024-10-28

guaifenesin and Airway Obstruction

guaifenesin has been researched along with Airway Obstruction in 208 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"Corticosteroid treatment reduces cough frequency concurrently with reductions in deltaPpl(max) and mucus accumulation in RAO-affected horses."2.71Coughing, mucus accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction. ( Berney, C; Cornelisse, CJ; deFeijter-Rupp, HL; Derksen, FJ; Eberhart, S; Gerber, VM; Jefcoat, AM; Robinson, NE, 2003)
"Although airway obstruction is common in people with motor or neurologic disorders and in those who are chronically debilitated or institutionalized, food and foreign matter are not the only culprits."2.45Case study: Asphyxia caused by inspissated oral and nasopharyngeal secretions. ( Prahlow, JA; Prahlow, ND; Prahlow, TJ; Rakow, RJ, 2009)
"Cough is an important component of airway clearance, particularly in individuals with intrinsic pulmonary disease, weakness of respiratory muscles, or central nervous system disease that impairs breathing."2.44Mechanical insufflation-exsufflation for airway mucus clearance. ( Homnick, DN, 2007)
"Heaves, or recurrent airway obstruction (RAO), is a chronic respiratory disease featuring lower airway inflammation, bronchoconstriction, and mucus accumulation."2.42Recurrent airway obstruction--heaves. ( Léguillette, R, 2003)
"Chronic obstructive pulmonary disease (COPD) is a disease state characterised by airflow obstruction that is not fully reversible and progressive."2.42[Pathophysiology of chronic obstructive pulmonary disease]. ( Maestrelli, P, 2003)
"Also the degree of airway obstruction is related to the physical properties of the sputum."2.40Lung mucus: a clinician's view. ( Kim, WD, 1997)
"Among the 4483 participants with COPD, 4363 were included in the primary analysis (median age, 63 years [IQR, 57-70 years]; 44% were women)."1.91Airway-Occluding Mucus Plugs and Mortality in Patients With Chronic Obstructive Pulmonary Disease. ( Abozeed, M; Ahmed, AN; Aziz, MU; Cho, M; Diaz, AA; Dolliver, WR; Grumley, S; Han, MK; Jacobs, K; Kim, V; Kligerman, SJ; Make, BJ; Manapragada, PP; Nath, HP; Orejas, JL; San José Estépar, R; Sonavane, S; Terry, NL; Wang, W; Washko, GR; Yen, A; Zahid, M, 2023)
"The percentages of airway obstruction due to mucus plugs were notably higher in the fourth- and fifth-generation bronchi (17."1.56Changes in airway diameter and mucus plugs in patients with asthma exacerbation. ( Kurashima, K; Nakamoto, Y; Takaku, Y; Takayanagi, N; Takizawa, H; Yanagisawa, T; Yoshida, Y, 2020)
"Pretreatment with diminazene aceturate, a small molecule with ability to inhibit acid detection through blockade of the acid-sensing ion channel (ASIC) at the doses provided, did not prevent acid-induced pathologic mucus or transport defects but did mitigate airway obstruction."1.56Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. ( Atanasova, KR; Bravo, L; Collins, EN; Dadural, JS; Eken, E; Guevara, MV; Kuan, SP; Liao, YSJ; Reznikov, LR; Schurmann, V; Sponchiado, M; Vogt, K, 2020)
"Central airway obstruction (CAO) is defined as obstruction of the airway lumen in the trachea or mainstem bronchi, most commonly due to primary or metastatic malignancy; and is classified as extraluminal, endoluminal, or mixed."1.51A Single Center Experience of Feasibility of a Novel Self-Expanding Metallic Airway Stent (Bonastent): A Case Series. ( Chawla, M; Lee, R; Makkar, P; Revelo, A, 2019)
"As recurrent airway obstruction (RAO) is progressive and as medical history is frequently unknown by owners, it's important to suggest a score model to characterize RAO stages for a more accurate diagnosis and treatment."1.38Correlation and discriminant analysis between clinical, endoscopic, thoracic X-ray and bronchoalveolar lavage fluid cytology scores, for staging horses with recurrent airway obstruction (RAO). ( Branco Ferreira, M; Sales Luis, JP; Tilley, P, 2012)
"Lower respiratory tract infections were associated with decreased survival (HR = 1."1.38Respiratory infections increase the risk of granulation tissue formation following airway stenting in patients with malignant airway obstruction. ( Eapen, GA; Godoy, MCB; Jani, P; Jimenez, CA; Larson, AJ; Lei, X; Morice, RC; Ost, DE; Sarkiss, MG; Shah, AM, 2012)
"It may be performed to relieve upper airway obstruction from congenital stenoses or from acquired conditions such as foreign body impaction, swelling from neck trauma or anaphylaxis, benign or malignant tumors, and infection."1.37Potentially lethal complications of tracheostomy: autopsy considerations. ( Byard, RW; Gilbert, JD, 2011)
"Cast bronchitis is a rare but potentially fatal condition caused by the accumulation of mucus in the bronchial tree usually secondary to infection, inflammation, or vascular stasis."1.35Thoracic air leakage in the presentation of cast bronchitis. ( Kerem, E; Kruger, J; Picard, E; Shpringer, C, 2009)
"The etiology of the acutely developed atelectasis was unclear."1.34Pulmonary atelectasis manifested after induction of anesthesia: a contribution of sinobronchial syndrome? ( Amagasa, S; Igarashi, A; Oda, S; Yokoo, N, 2007)
"Airway eosinophilia was observed during both responses."1.33Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma. ( Arakawa, H; Koyama, H; Mayuzumi, H; Mizuno, T; Mochizuki, H; Morikawa, A; Nishimura, H; Ohki, Y; Tokuyama, K, 2005)
"RAO-affected horses had more airway obstruction and luminal mucus than control horses under both management systems."1.33Persistent mucus accumulation: a consequence of delayed bronchial mucous cell apoptosis in RAO-affected horses? ( Bartner, LR; Kiupel, M; Robinson, NE; Tesfaigzi, Y, 2006)
"Plastic bronchitis is an infrequent cause of acute life-threatening respiratory failure that can mimic foreign body aspiration or status asthmaticus."1.32Plastic bronchitis mimicking foreign body aspiration that needs a specific diagnostic procedure. ( Brichet, A; Cremer, R; Dorkenoo, A; Fourier, C; Leclerc, F; Leteurtre, S; Noizet, O; Pouessel, G, 2003)
"These findings suggest that bronchial asthma with mucoid impactions is among several pathogeneses that cause increased levels of CEA in serum and BALF."1.32[Concentrations of carcinoembryonic antigen in serum and bronchoalveolar lavage fluid of asthmatic patients with mucoid impaction]. ( Fukui, Y; Harada, T; Hizawa, N; Kikuchi, E; Maeda, Y; Nagai, K; Nishimura, M; Suko, N; Takahashi, D, 2004)
"Plastic bronchitis was observed in 44 years old man, who expectorated white, branching, bronchial casts for three months."1.31[Plastic bronchitis and mucoid impaction--uncommon disease syndromes with expectoration mucus plugs]. ( Bestry, I; Pirozynski, M; Płodziszewska, M; Rowińska-Zakrzewska, E; Sledziewska, J; Wiatr, E; Załeska, J; Załeska, M, 2001)
"Despite the severe degree of atelectasis, he exhibited only mild respiratory distress."1.31Atelectasis and mucus plugging in spinal cord injury: case report and therapeutic approaches. ( Aguilera, EJ; Slonimski, M, 2001)
"Although rare, major lung collapse secondary to mucous plugging should be considered in the differential diagnosis of intraoperative hypoxaemia, particularly following major trauma."1.28Profound intraoperative atelectasis. ( Brodsky, JB; Samuels, SI, 1989)
"In the case reported here, airway obstruction by a large mucous-like plug apparently developed in the context of severe oligohydramnios and fetal distress."1.27Tracheal plugs in oligohydramnios. ( Ewy, GI; Kuruvilla, AC, 1988)

Research

Studies (208)

TimeframeStudies, this research(%)All Research%
pre-199074 (35.58)18.7374
1990's25 (12.02)18.2507
2000's55 (26.44)29.6817
2010's42 (20.19)24.3611
2020's12 (5.77)2.80

Authors

AuthorsStudies
Sorenson, HM1
McIntosh, MJ2
Kooner, HK2
Eddy, RL3
Jeimy, S1
Licskai, C2
Mackenzie, CA2
Svenningsen, S2
Nair, P2
Yamashita, C2
Parraga, G3
Cedano, J1
Choi, J1
Castro, M1
Wilson, A1
Serajeddini, H1
Bhalla, A1
Bessonov, N1
Volpert, V1
Diaz, AA1
Orejas, JL1
Grumley, S1
Nath, HP1
Wang, W1
Dolliver, WR1
Yen, A1
Kligerman, SJ1
Jacobs, K1
Manapragada, PP1
Abozeed, M1
Aziz, MU1
Zahid, M1
Ahmed, AN1
Terry, NL1
San José Estépar, R2
Kim, V1
Make, BJ1
Han, MK1
Sonavane, S1
Washko, GR1
Cho, M1
Fiorelli, A1
Natale, G1
Freda, C1
Cascone, R1
Carlucci, A2
Costanzo, S1
Ferrara, V1
Santini, M1
Balázs, A1
Mall, MA6
Yoshida, Y1
Takaku, Y1
Nakamoto, Y1
Takayanagi, N1
Yanagisawa, T1
Takizawa, H1
Kurashima, K1
Liao, YSJ1
Kuan, SP1
Guevara, MV1
Collins, EN1
Atanasova, KR1
Dadural, JS1
Vogt, K1
Schurmann, V1
Bravo, L1
Eken, E1
Sponchiado, M1
Reznikov, LR1
Linssen, RS1
Chai, G1
Ma, J1
Kummarapurugu, AB1
van Woensel, JBM1
Bem, RA1
Kaler, L1
Duncan, GA1
Zhou, L1
Rubin, BK4
Xu, Q1
Comegna, M1
Conte, G1
Falanga, AP1
Marzano, M1
Cernera, G1
Di Lullo, AM1
Amato, F1
Borbone, N1
D'Errico, S1
Ungaro, F1
d'Angelo, I1
Oliviero, G1
Castaldo, G1
Yoshida, M1
Miyahara, Y1
Orimo, K1
Kono, N1
Narita, M1
Ohya, Y1
Matsumoto, K1
Nakagawa, S1
Ueki, S1
Morita, H1
Miyairi, I1
Jiang, M1
Fang, Y1
Li, Y1
Huang, H1
Wei, Z1
Gao, X1
Sung, HK1
Hu, J1
Qiang, L1
Ruan, J1
Chen, Q1
Jiang, D1
Whitsett, JA1
Ai, X1
Que, J1
Cao, LJ1
Liu, JH2
Shuai, JF1
Niu, B1
Lu, SK1
Huang, KL1
Masood, MM1
Farquhar, DR1
Biancaniello, C1
Hackman, TG1
Delgado Pecellín, I1
Moreno Ortega, M1
Carrasco Hernández, L1
Marín Barrera, L1
Muñoz Zara, P1
Moreno Valera, MJ1
Quintana Gallego, ME1
Han, J1
Xiang, H1
Ridley, WE1
Ridley, LJ1
Worren, MK1
Storesund, AK1
Sharma, R1
Vintermyr, OK1
Gjerde, S1
Flaatten, HK1
Dunican, EM1
Watchorn, DC1
Fahy, JV4
Small, DM1
Brown, RR1
Doherty, DF1
Abladey, A1
Zhou-Suckow, Z2
Delaney, RJ1
Kerrigan, L1
Dougan, CM1
Borensztajn, KS1
Holsinger, L1
Booth, R1
Scott, CJ1
López-Campos, G1
Elborn, JS1
Weldon, S1
Taggart, CC1
Haider, E1
Boylan, C1
Mukherjee, M1
Capaldi, DPI1
Makkar, P1
Revelo, A1
Lee, R1
Chawla, M1
Crespo-Lessmann, A1
Torrego-Fernández, A1
Shah, RJ1
Kotloff, RM1
Volsko, TA1
Mietto, C1
Foley, K1
Salerno, L1
Oleksak, J1
Pinciroli, R1
Goverman, J1
Berra, L1
Gehrig, S1
Duerr, J3
Weitnauer, M1
Wagner, CJ2
Graeber, SY1
Schatterny, J3
Hirtz, S3
Belaaouaj, A1
Dalpke, AH1
Schultz, C2
Trojanek, JB1
Cobos-Correa, A1
Diemer, S1
Kormann, M1
Schubert, SC1
Agrawal, R2
Sommerburg, O1
Hartl, D1
Currie, LL1
Medford, AR1
Patel, A1
Theokli, C1
Woittiez, KJ1
Woittiez, AJ1
da Cunha, AA1
Nuñez, NK1
de Souza, RG1
Moraes Vargas, MH1
Silveira, JS1
Antunes, GL1
Durante, Lda S1
Porto, BN1
Marczak, ES1
Jones, MH1
Pitrez, PM1
Bonser, LR1
Zlock, L1
Finkbeiner, W1
Erle, DJ1
Capasso, R1
Carbone, M1
Rossi, E1
Mamone, R1
Zeccolini, R1
Reginelli, A1
Zeccolini, M1
Brunese, L1
Rotondo, A1
Panchabhai, TS1
Mukhopadhyay, S1
Sehgal, S1
Bandyopadhyay, D1
Erzurum, SC1
Mehta, AC1
Soler, X1
Mahmoud, M1
Smith, G1
Subramanyam, R1
Ryhner, T1
Müller, N1
Balmer, V1
Gerber, V4
Avena, Kde M1
Duarte, AC1
Cravo, SL1
Sologuren, MJ1
Gastaldi, AC1
Volpe, MS1
Adams, AB1
Amato, MB1
Marini, JJ3
Agrawal, A1
Mabalirajan, U1
Ram, A1
Ghosh, B1
Evans, CM1
Kim, K1
Tuvim, MJ1
Dickey, BF1
Tumes, DJ1
Connolly, A1
Dent, LA1
Kravitz, RM1
Prahlow, JA1
Prahlow, TJ1
Rakow, RJ1
Prahlow, ND1
Xue, FS1
Luo, MP1
Liao, X1
Zhang, YM1
Kruger, J1
Shpringer, C1
Picard, E1
Kerem, E1
Tiddens, HA1
Donaldson, SH1
Rosenfeld, M1
Paré, PD2
Hasegawa, M1
Inamo, Y1
Fuchigami, T1
Hashimoto, K1
Morozumi, M1
Ubukata, K1
Watanabe, H1
Takahashi, T1
Burgel, PR1
Martin, C1
Stone, RH1
Bricknell, SS1
Wielpütz, MO1
Eichinger, M1
Zhou, Z1
Leotta, K1
Bartling, SH1
Semmler, W1
Kauczor, HU1
Puderbach, M1
Rousseau, K1
Cardwell, JM1
Humphrey, E1
Newton, R1
Knight, D1
Clegg, P1
Thornton, DJ1
Ntoumenopoulos, G1
Shannon, H1
Main, E1
Byard, RW1
Gilbert, JD1
Knox, T1
Tilley, P1
Sales Luis, JP1
Branco Ferreira, M1
Ost, DE1
Shah, AM1
Lei, X1
Godoy, MCB1
Jimenez, CA1
Eapen, GA1
Jani, P1
Larson, AJ1
Sarkiss, MG1
Morice, RC1
Livraghi-Butrico, A1
Grubb, BR1
Kelly, EJ1
Wilkinson, KJ1
Yang, H1
Geiser, M1
Randell, SH1
Boucher, RC1
O'Neal, WK1
Schreiber, A1
Nava, S1
Ceriana, P1
Law, JA1
Mariotti, C1
Mullen, T1
Anagnostopoulou, P1
Riederer, B1
Michel, S1
Binia, A1
Liu, X1
Kalitzki, K1
Xiao, F1
Chen, M1
Hartmann, D1
Thum, T1
Kabesch, M1
Soleimani, M1
Seidler, U1
Kreda, SM1
Davis, CW1
Rose, MC2
Hong, WS1
Im, SA1
Kim, HL1
Yoon, JS1
Postiaux, G1
Zwaenepoel, B1
Louis, J1
Nair, SR1
Pearson, SB1
Noizet, O1
Leclerc, F1
Leteurtre, S1
Brichet, A1
Pouessel, G1
Dorkenoo, A1
Fourier, C1
Cremer, R1
Léguillette, R1
Robinson, NE5
Berney, C1
Eberhart, S1
deFeijter-Rupp, HL1
Jefcoat, AM3
Cornelisse, CJ1
Gerber, VM1
Derksen, FJ1
Venta, RJ1
Rawson, J1
Hotchkiss, JA2
Swischuk, LE1
Hashimoto, Y1
Murata, A1
Mikami, M1
Nakamura, S1
Yamanaka, E1
Kudoh, S1
Kuyper, LM1
Hogg, JC2
Lambert, RK1
Ionescu, D1
Woods, R1
Bai, TR1
Hays, SR1
MANNES, P1
SEVERIN, A1
DUPREZ, A1
Aizawa, H1
Groneberg, DA1
Wagner, U1
Chung, KF1
Maestrelli, P1
Deaton, CM1
Marlin, DJ1
Smith, NC1
Smith, KC1
Newton, RJ1
Gower, SM1
Cade, SM1
Roberts, CA1
Harris, PA1
Schroter, RC1
Kelly, FJ1
Rogers, DF1
Shoun, P1
Steelman, R1
Barber, B1
Olson, M1
Pate, MF1
Zimmerman, AT1
Nagata, K1
Iwasaki, Y1
Yamada, T1
Yuba, T1
Kohno, K1
Hosogi, S1
Ohsugi, S1
Kuwahara, H1
Yokomura, I1
Maeda, Y1
Hizawa, N1
Fukui, Y1
Nagai, K1
Kikuchi, E1
Takahashi, D1
Harada, T1
Suko, N1
Nishimura, M1
Koyama, H1
Tokuyama, K1
Nishimura, H1
Mizuno, T1
Mayuzumi, H1
Ohki, Y1
Arakawa, H1
Mochizuki, H1
Morikawa, A1
Ferreres-Franco, J1
Blanquer-Olivas, J1
Pastor-Esplá, E1
Borrás-Pallé, S1
Galán-Gil, G1
Jordá-Miñana, A1
Zamanian, M1
Bartner, LR1
Kiupel, M1
Tesfaigzi, Y1
Muz, MH1
Deveci, F1
Bulut, Y1
Ilhan, N1
Yekeler, H1
Turgut, T1
Panitch, HB1
Igarashi, A1
Amagasa, S1
Oda, S1
Yokoo, N1
Fink, JB1
Corry, DB2
Kheradmand, F1
Hashida, F1
Komori, M1
Nishiyama, K1
Taniguchi, Y1
Kondo, I1
Kawamata, M1
Ozaki, M1
Homnick, DN1
Haas, CF1
Loik, PS1
Gay, SE1
Schechter, MS1
Hess, DR1
Therien, AG1
Bernier, V1
Weicker, S1
Tawa, P1
Falgueyret, JP1
Mathieu, MC1
Honsberger, J1
Pomerleau, V1
Robichaud, A1
Stocco, R1
Dufresne, L1
Houshyar, H1
Lafleur, J1
Ramachandran, C1
O'Neill, GP1
Slipetz, D1
Tan, CM1
Todisco, T1
Dottorini, M1
Nowak, RM1
Casale, TB1
Marom, Z2
Bray, ST2
Johnstone, WH1
Dee, PM2
Pope, TL1
Teates, CD1
Tegtmeyer, CJ1
Pokora, T1
Bing, D1
Mammel, M1
Boros, S1
Weiss, T1
Dorow, P1
Felix, R1
Suratt, PM1
Rose, CE1
Chodosh, S1
Zanjanian, MH1
Middleton, E1
Atkins, FM1
Fanning, M1
Georgitis, JW1
Denneny, JC1
Handler, SD1
Wanner, A2
Hudgel, DW1
Shucard, DW1
Ketha, S1
Diaz, C1
Farrow, J1
Mehta, J1
Ulstad, DR1
Koppin, J1
Van Surell, C1
Louis, B1
Lofaso, F1
Beydon, L1
Brochard, L1
Harf, A1
Fredberg, J1
Isabey, D1
de Groot, RE1
Dik, H1
de Groot, HG1
Bakker, W1
Duncan, W1
Tyrrell, M1
Bharadwaj, B1
George, D1
Rothe, TB1
Frey, JG1
Ciobanu, TD1
Karrer, W1
Hansell, DM1
Rubens, MB1
Padley, SP1
Wells, AU1
Kim, WD1
Cohen, SP1
Anderson, PL1
Denehy, L1
Boushey, HA2
Hill, NS1
Wood, KE1
Flaten, AL1
Backes, WJ1
Blackburn, MR1
Volmer, JB1
Thrasher, JL1
Zhong, H1
Crosby, JR1
Lee, JJ1
Kellems, RE1
King, M2
Schneider, DA1
Bitsori, M1
Galanakis, E1
Paraskakis, E1
Papadakis, CE1
Kokori, H1
Sbyrakis, S1
Sledziewska, J1
Załeska, J1
Wiatr, E1
Płodziszewska, M1
Załeska, M1
Pirozynski, M1
Bestry, I1
Rowińska-Zakrzewska, E1
El Hassan, NO1
Chess, PR1
Huysman, MW1
Merkus, PJ1
de Jongste, JC1
Harkema, JR1
Basbaum, CB1
Nickola, TJ1
Voynow, JA1
Tomkiewicz, R1
Green, FH1
Slonimski, M1
Aguilera, EJ1
Proctor, DF1
Adams, GK1
Pavia, D1
Bateman, JR1
Sheahan, NF1
Clarke, SW1
Helders, PJ1
Rasche, B1
Hochstrasser, K1
Ulmer, WT1
Aurnhammer, W1
Konietzko, N1
Matthys, H1
Speizer, FE1
Tager, IB1
Fairshter, RD1
Riley, CA1
Hewlett, RI1
Felson, B1
Minette, A1
Donaldson, JC1
Stoop, DR1
Raymond, LW1
Royall, JD1
Hippensteel, KE1
Cobb, OM1
Hong, ND1
Newhouse, M1
Sanchis, J1
Bienenstock, J1
Fletcher, C1
Peto, R1
Reid, L1
Wick, MM1
Ingram, RH1
Katzenstein, AL1
Liebow, AA1
Friedman, PJ1
Hewlett, AM1
Branthwaite, MA1
Wood, RE1
Hirsch, J1
Farrell, PM1
Fortin, D1
Davidson, KC1
Perlman, M1
Williams, J1
Hirsch, M1
Bar-Ziv, J1
Elmes, PC1
Bignon, J1
Depierre, A1
André-Bougaran, J1
Hem, B1
Cairns-Bazarian, AM1
Conway, EE1
Yankelowitz, S1
Lundgren, JD2
Charlton, GA1
Torlot, KJ1
Hacking, CN1
Roth, BJ1
Irvine, TW1
Liening, DA1
Duncan, NO1
Cragun, WH1
van der Werf, TS1
Meinesz, AF1
Postmus, PE1
Hoffman, LA1
Reinke, LF1
Wesmiller, SW1
Sciurba, FC1
Harrow, EM1
Oldenburg, FA1
Lingenfelter, MS1
Leonard, J1
Spurzem, JR1
Thompson, AB1
Daughton, DM1
Mueller, M1
Linder, J1
Rennard, SI1
Bolliger, CT1
Perruchoud, AP1
Garvin, JM1
Davey, RT1
Lundgren, B1
Mullol, J1
Logun, C1
Baraniuk, J1
Kaliner, MA2
Shelhamer, JH1
Wiles, FJ1
Hnizdo, E1
Piacentini, GL1
Burton, GG1
Wagshul, FA1
Henderson, D1
Kime, SW1
Mah, MW1
Jones, RL1
Man, GC1
Skippen, PW1
York, EL1
Bhaskar, KR1
O'Sullivan, DD1
Coles, SJ1
Kozakewich, H1
Vawter, GP1
Reid, LM2
Nadel, JA1
Lin, DC1
Hsu, L1
Huang, PY1
Agarwal, M1
Shukla, JB1
Sjaastad, O1
Saunte, C1
Salvesen, R1
Fredriksen, TA1
Seim, A1
Røe, OD1
Fostad, K1
Løbben, OP1
Zhao, JM1
Velchik, MG1
Tobin, M1
Leadbeatter, S1
Douglas-Jones, AG1
Samuels, SI1
Brodsky, JB1
Davis, PB1
Pride, NB1
Ewy, GI1
Kuruvilla, AC1
Muller, AF1
Mithal, A1
Cohn, JR1
Steiner, RM1
Posuniak, E1
Northrup, BE1
Drazen, JM1
Holgate, ST1
Kaliner, M1
O'Byrne, P1
Valentine, M1
Widdicombe, JH1
Woolcock, A1
Lockhart, JS1
Griffin, C1
Rubin, EM1
Baier, H1
Vereen, LE1
Payne, DK1
George, RB1
Suez, D1
Szefler, SJ1
Paisner, HM1
Dunnill, MS1
Keal, E1
Thurlbeck, WM2
Blue, JA1
Iravani, J1
Matsuba, K1
Madewell, JE1
Montgomery, JL1
Cavanagh, RC1
Irwin, RS1
Thomas, HM1
McLaughlin, AD1
Linhartovã, A1
Anderson, AE1
Foraker, AG1
Piscicelli, I1
Matturro, F1
Genereux, GP1

Clinical Trials (17)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Mechanistic Pilot Open-label Study to Evaluate the Effect of Benralizumab on Airway Function and Inflammation in Patients With Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI[NCT03733535]29 participants (Actual)Interventional2022-03-01Active, not recruiting
A Two-arm, Placebo-controlled, Randomized Clinical Trial to Evaluate the Effect of Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe Asthma[NCT05280418]Phase 330 participants (Anticipated)Interventional2022-11-08Recruiting
Air Stacking Technique For Pulmonary Reexpansion In The Ventilator After Expiratory Pause During Aspiration In Closed System[NCT05702411]39 participants (Anticipated)Interventional2021-09-01Recruiting
Bronchial Inflammation of Small Airways in Patients With Cystic Fibrosis[NCT01479166]20 participants (Actual)Observational2011-06-30Completed
Endotracheal Tubes Cleaned With a Novel Mechanism for Secretions Removal[NCT01765530]74 participants (Actual)Interventional2012-09-30Completed
Selecting the Best Ventilator Hyperinflation Settings Based on Physiologic Markers: Randomized Controlled Study[NCT03327610]30 participants (Actual)Interventional2016-07-31Completed
Multicenter Randomized Controlled Trial: Evaluation of the Effects of Respiratory Physiotherapy, Placebo-controlled, in Infants With Moderate Acute Bronchiolitis[NCT03753802]168 participants (Anticipated)Interventional2019-12-01Recruiting
Bronchial Thermoplasty: Mechanism of Action and Defining Asthma Phenotype[NCT02075151]50 participants (Anticipated)Interventional2014-02-28Not yet recruiting
Clinical Trial of NAC in Asthma[NCT02605824]Phase 41 participants (Actual)Interventional2016-03-31Terminated (stopped due to The study was closed after we determined that this albuterol/NAC regimen may be associated with excessive bronchoconstriction.)
The Effect of NAC on Lung Function and CT Mucus Score[NCT03822637]Phase 430 participants (Anticipated)Interventional2019-02-20Recruiting
Inpatient Clinical Trial of NAC[NCT03581084]Phase 41 participants (Actual)Interventional2018-07-06Terminated (stopped due to The study was redesigned to be conducted in an outpatient setting.)
The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC[NCT06152653]Phase 420 participants (Anticipated)Interventional2023-11-21Recruiting
Mechanical Insufflation-Exsufflation Compared With CPAP in Patients Admitted to an Intermediate Care Unit With Pneumonia: a Randomised Controlled Study.[NCT03714321]30 participants (Actual)Interventional2014-01-01Completed
A Comparison of Three Methods for Improving Expiratory Cough Flow and Lung Volume in Children With Neuromuscular Diseases[NCT02342132]40 participants (Actual)Interventional2014-08-31Completed
Chest Therapy and Postural Control in Children With Crhonic Neurological Patology[NCT03946137]30 participants (Actual)Interventional2013-09-30Completed
"FIBARRIX Clinical Evaluation of the Response to Chest Physiotherapy in Infants With Acute Bronchiolitis"[NCT02458300]77 participants (Actual)Interventional2015-01-31Completed
[NCT00005281]0 participants Observational1977-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

ETT Microbiology

For each patient a quantitative culture will be obtained from the ETT after extubation. Secretions will be retrieved from the ETT after CT scan and quantitative standard cultures will be performed. Microbial molecular diversity analysis and antibacterial resistance patterns will also be studied. (NCT01765530)
Timeframe: At extubation (An expected average of 5 days)

InterventionLog colony form unit (CFU)/ mL (Mean)
ETT Cleaning Manuver2.89
Standard of Care3.35

Percentage of Occlusion Assessed Using a High Definition Computed Tomography Imaging of the Extubated ETTs

The investigators will measure percentage of occlusion determined by the accumulation of secretion within the lumen of each ETT using a high definition Computed Tomography (CT) imaging of the extubated ETTs. The whole ETT will be analyzed through high-definition CT slices. 100% of occlusion means total occlusion of the lumen of the ETT and 0% means absence of any occlusion. (NCT01765530)
Timeframe: At extubation (An expected average of 5 days)

Interventionpercentage of occlusion (Mean)
ETT Cleaning Manuver10.6
Standard of Care17.7

Forced Expiratory Volume in One Second (FEV1) Measurement

Post-treatment FEV1 is reported. FEV1 is measured via spirometry. (NCT03581084)
Timeframe: end of the one week treatment period

Interventionliters (Number)
N-acetylcysteine0.86

Reviews

40 reviews available for guaifenesin and Airway Obstruction

ArticleYear
Managing secretions in dying patients.
    Respiratory care, 2000, Volume: 45, Issue:11

    Topics: Adrenergic beta-Agonists; Airway Obstruction; Analgesics, Opioid; Anti-Inflammatory Agents; Expector

2000
Mucus obstruction and inflammation in early cystic fibrosis lung disease: Emerging role of the IL-1 signaling pathway.
    Pediatric pulmonology, 2019, Volume: 54 Suppl 3

    Topics: Airway Obstruction; Animals; Child; Child, Preschool; Cystic Fibrosis; Disease Models, Animal; Human

2019
Autopsy and Imaging Studies of Mucus in Asthma. Lessons Learned about Disease Mechanisms and the Role of Mucus in Airflow Obstruction.
    Annals of the American Thoracic Society, 2018, Volume: 15, Issue:Suppl 3

    Topics: Airway Obstruction; Asthma; Autopsy; Cytokines; Eosinophils; Humans; Mucus; Multidetector Computed T

2018
Airway clearance therapy: finding the evidence.
    Respiratory care, 2013, Volume: 58, Issue:10

    Topics: Airway Obstruction; Drainage, Postural; Humans; Mucociliary Clearance; Mucus; Respiratory Therapy

2013
Plugs of the Air Passages: A Clinicopathologic Review.
    Chest, 2016, Volume: 150, Issue:5

    Topics: Airway Obstruction; Bronchi; Bronchoscopy; Humans; Mucus

2016
Novel approaches for inhibition of mucus hypersecretion in asthma.
    Recent patents on inflammation & allergy drug discovery, 2007, Volume: 1, Issue:3

    Topics: Airway Obstruction; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Elasticity; Ex

2007
Mucus hypersecretion in asthma: causes and effects.
    Current opinion in pulmonary medicine, 2009, Volume: 15, Issue:1

    Topics: Airway Obstruction; Asthma; Humans; Lung; Mucin 5AC; Mucin-5B; Mucus

2009
Airway clearance in Duchenne muscular dystrophy.
    Pediatrics, 2009, Volume: 123 Suppl 4

    Topics: Acute Disease; Airway Obstruction; Child; Cough; Humans; Mucus; Muscular Dystrophy, Duchenne; Respir

2009
Case study: Asphyxia caused by inspissated oral and nasopharyngeal secretions.
    The American journal of nursing, 2009, Volume: 109, Issue:6

    Topics: Airway Obstruction; Asphyxia; Autopsy; Causality; Cause of Death; Cerebral Palsy; Diagnostic Errors;

2009
Cystic fibrosis lung disease starts in the small airways: can we treat it more effectively?
    Pediatric pulmonology, 2010, Volume: 45, Issue:2

    Topics: Administration, Inhalation; Airway Obstruction; Airway Remodeling; Anti-Inflammatory Agents; Child;

2010
CFTR, mucins, and mucus obstruction in cystic fibrosis.
    Cold Spring Harbor perspectives in medicine, 2012, Sep-01, Volume: 2, Issue:9

    Topics: Airway Obstruction; Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; D

2012
Chest physical therapy in acute viral bronchiolitis: an updated review.
    Respiratory care, 2013, Volume: 58, Issue:9

    Topics: Airway Obstruction; Algorithms; Bronchiolitis, Viral; Edema; Humans; Infant; Mucus; Nebulizers and V

2013
Recurrent airway obstruction--heaves.
    The Veterinary clinics of North America. Equine practice, 2003, Volume: 19, Issue:1

    Topics: Adrenal Cortex Hormones; Airway Obstruction; Animals; Bronchoalveolar Lavage; Chronic Disease; Horse

2003
[Mechanisms and control of airway remodeling].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2003, Volume: 41, Issue:9

    Topics: Airway Obstruction; Asthma; Basement Membrane; Bronchi; Bronchial Hyperreactivity; Constriction, Pat

2003
[Pathophysiology of chronic obstructive pulmonary disease].
    Annali dell'Istituto superiore di sanita, 2003, Volume: 39, Issue:4

    Topics: Airway Obstruction; Ciliary Motility Disorders; Humans; Inflammation Mediators; Mucus; Pulmonary Dis

2003
Airway mucus hypersecretion in asthma: an undervalued pathology?
    Current opinion in pharmacology, 2004, Volume: 4, Issue:3

    Topics: Airway Obstruction; Asthma; Cytokines; Humans; Mucus; Phenotype; Pulmonary Disease, Chronic Obstruct

2004
Airway clearance in children with neuromuscular weakness.
    Current opinion in pediatrics, 2006, Volume: 18, Issue:3

    Topics: Airway Obstruction; Child; Child, Preschool; Cough; Humans; Infant; Mucus; Muscle Weakness; Neuromus

2006
Novel medications for asthma: a look at the future.
    Expert opinion on investigational drugs, 2007, Volume: 16, Issue:6

    Topics: Airway Obstruction; Animals; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Drug Delivery

2007
Mechanical insufflation-exsufflation for airway mucus clearance.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Cough; Equipment Design; Humans; Insufflation; Mucus

2007
Mechanical insufflation-exsufflation for airway mucus clearance.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Cough; Equipment Design; Humans; Insufflation; Mucus

2007
Mechanical insufflation-exsufflation for airway mucus clearance.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Cough; Equipment Design; Humans; Insufflation; Mucus

2007
Mechanical insufflation-exsufflation for airway mucus clearance.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Cough; Equipment Design; Humans; Insufflation; Mucus

2007
Airway clearance applications in the elderly and in patients with neurologic or neuromuscular compromise.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Aged; Aging; Airway Obstruction; Humans; Lung; Mucus; Nervous System Diseases; Neuromuscular Disease

2007
Airway clearance applications in infants and children.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Age Factors; Airway Obstruction; Child; Child, Preschool; Humans; Infant; Mucus; Physical Therapy Mo

2007
Airway clearance applications in infants and children.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Age Factors; Airway Obstruction; Child; Child, Preschool; Humans; Infant; Mucus; Physical Therapy Mo

2007
Airway clearance applications in infants and children.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Age Factors; Airway Obstruction; Child; Child, Preschool; Humans; Infant; Mucus; Physical Therapy Mo

2007
Airway clearance applications in infants and children.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Age Factors; Airway Obstruction; Child; Child, Preschool; Humans; Infant; Mucus; Physical Therapy Mo

2007
Acute bronchial asthma.
    Emergency medicine clinics of North America, 1983, Volume: 1, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aero

1983
Expectorants and antitussive agents: are they helpful?
    Annals of allergy, 1980, Volume: 44, Issue:5

    Topics: Airway Obstruction; Antitussive Agents; Bronchi; Cough; Expectorants; Humans; Immunoglobulin A; Immu

1980
Cellular mechanisms in the pathogenesis and pathophysiology of asthma.
    The Medical clinics of North America, 1981, Volume: 65, Issue:5

    Topics: Aged; Airway Obstruction; Asthma; Atropine; Bronchial Spasm; Calcium; Eosinophils; Humans; Immunity,

1981
Lung mucus: a clinician's view.
    The European respiratory journal, 1997, Volume: 10, Issue:8

    Topics: Airway Obstruction; Bronchial Diseases; Humans; Lung; Mucus; Sputum

1997
The use of manual hyperinflation in airway clearance.
    The European respiratory journal, 1999, Volume: 14, Issue:4

    Topics: Airway Obstruction; Humans; Intubation, Intratracheal; Mucus; Physical Therapy Modalities; Respirati

1999
Airway inflammation and remodeling in asthma.
    Current opinion in pulmonary medicine, 2000, Volume: 6, Issue:1

    Topics: Airway Obstruction; Asthma; Basement Membrane; Bronchi; Bronchial Hyperreactivity; Bronchitis; Const

2000
Complications of noninvasive ventilation.
    Respiratory care, 2000, Volume: 45, Issue:5

    Topics: Acute Disease; Airway Obstruction; Humans; Incidence; Mucus; Positive-Pressure Respiration; Respirat

2000
Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:5

    Topics: Airway Obstruction; Gene Expression Regulation; Glycoproteins; Goblet Cells; Humans; Hyperplasia; Mu

2001
Physiology and pharmacology of nasal function and mucus secretion.
    Pharmacology & therapeutics. Part B: General & systematic pharmacology, 1976, Volume: 2, Issue:3

    Topics: Airway Obstruction; Anesthetics, Local; Headache; Hearing Disorders; Histamine H1 Antagonists; Human

1976
Epidemiology of chronic mucus hypersecretion and obstructive airways disease.
    Epidemiologic reviews, 1979, Volume: 1

    Topics: Age Factors; Air Pollution; Airway Obstruction; Alcoholic Intoxication; Child; Female; Humans; Hyper

1979
Lung defense mechanisms (first of two parts).
    The New England journal of medicine, 1976, Oct-28, Volume: 295, Issue:18

    Topics: Airway Obstruction; Animals; Bronchi; Bronchitis; Cilia; Complement System Proteins; Cough; Cystic F

1976
Postoperative pulmonary function.
    British journal of anaesthesia, 1975, Volume: 47, Issue:2

    Topics: Age Factors; Airway Obstruction; Airway Resistance; Anesthesia; Bronchi; Carbon Dioxide; Cardiac Out

1975
Plastic bronchitis: an unusual cause of respiratory distress in children.
    Pediatric emergency care, 1992, Volume: 8, Issue:6

    Topics: Airway Obstruction; Bronchitis; Bronchoscopy; Humans; Infant; Male; Mucus; Respiratory Insufficiency

1992
Mucus production in the lower airways. A review of experimental studies.
    Danish medical bulletin, 1992, Volume: 39, Issue:4

    Topics: Airway Obstruction; Autonomic Nervous System; Bronchi; Enzymes; Humans; Inflammation; Models, Biolog

1992
The potential roles of leukotrienes in bronchial asthma.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 2

    Topics: Airway Obstruction; Asthma; Edema; Humans; Hypersensitivity, Immediate; Leukotriene Antagonists; Leu

1991
Fatal airway obstruction caused by a mucous ball from a transtracheal oxygen catheter.
    Chest, 1991, Volume: 99, Issue:6

    Topics: Airway Obstruction; Humans; Intubation, Intratracheal; Male; Middle Aged; Mucous Membrane; Mucus; Ox

1991
Epidemiology of bronchial hypersecretion: recent studies.
    European journal of respiratory diseases. Supplement, 1987, Volume: 153

    Topics: Airway Obstruction; Anti-Bacterial Agents; Asthma; Bronchial Diseases; Bronchitis; Epidemiologic Met

1987
Small airways disease.
    Human pathology, 1973, Volume: 4, Issue:2

    Topics: Airway Obstruction; Airway Resistance; Animals; Bronchitis; Chronic Disease; Dogs; Humans; Inflammat

1973
Sites and mechanisms of airway obstruction in COPD.
    Postgraduate medicine, 1973, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Airway Obstruction; Airway Resistance; Bronchi; Child; Child,

1973

Trials

5 trials available for guaifenesin and Airway Obstruction

ArticleYear
Asthma Control, Airway Mucus, and
    Chest, 2022, Volume: 162, Issue:3

    Topics: Airway Management; Airway Obstruction; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Ast

2022
[Efficacy of early treatment via fiber bronchoscope in children with Mycoplasma pneumoniae pneumonia complicated by airway mucus obstruction].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2018, Volume: 20, Issue:4

    Topics: Airway Obstruction; Bronchoscopes; Child; Child, Preschool; Female; Fiber Optic Technology; Humans;

2018
Coughing, mucus accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction.
    American journal of veterinary research, 2003, Volume: 64, Issue:5

    Topics: Airway Obstruction; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cough; Dexameth

2003
Effect of ipratropium bromide on mucociliary clearance and pulmonary function in reversible airways obstruction.
    Thorax, 1979, Volume: 34, Issue:4

    Topics: Aged; Airway Obstruction; Atropine Derivatives; Cilia; Clinical Trials as Topic; Double-Blind Method

1979
Problems in evaluating the effect of secretolytic agents on the mucociliary system by means of radioactive particles.
    Respiration; international review of thoracic diseases, 1977, Volume: 34, Issue:2

    Topics: Airway Obstruction; Airway Resistance; Bromhexine; Bronchi; Bronchitis; Chronic Disease; Clinical Tr

1977

Other Studies

163 other studies available for guaifenesin and Airway Obstruction

ArticleYear
Mucus Plugging: A New Phenotype for Your Practice.
    The journal of allergy and clinical immunology. In practice, 2023, Volume: 11, Issue:2

    Topics: Airway Obstruction; Humans; Mucus; Phenotype

2023
CT Mucus Score and
    Chest, 2023, Volume: 164, Issue:1

    Topics: Airway Obstruction; Anti-Asthmatic Agents; Asthma; Humans; Magnetic Resonance Imaging; Mucus; Nitric

2023
Airway obstruction in respiratory viral infections due to impaired mucociliary clearance.
    International journal for numerical methods in biomedical engineering, 2023, Volume: 39, Issue:11

    Topics: Airway Obstruction; Humans; Lung; Mucociliary Clearance; Mucus

2023
Airway-Occluding Mucus Plugs and Mortality in Patients With Chronic Obstructive Pulmonary Disease.
    JAMA, 2023, 06-06, Volume: 329, Issue:21

    Topics: Aged; Aged, 80 and over; Airway Obstruction; Cigarette Smoking; Female; Forced Expiratory Volume; Hu

2023
Montgomery T-tube for management of tracheomalacia: Impact on voice-related quality of life.
    The clinical respiratory journal, 2020, Volume: 14, Issue:1

    Topics: Aged; Airway Obstruction; Bronchoscopy; Case-Control Studies; Female; Humans; Intubation, Intratrach

2020
Changes in airway diameter and mucus plugs in patients with asthma exacerbation.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: Airway Obstruction; Asthma; Bronchi; Female; Humans; Male; Middle Aged; Mucus; Prognosis; Tomography

2020
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
    American journal of physiology. Lung cellular and molecular physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Airway Obstruction; Anima

2020
Neutrophil Extracellular Traps Increase Airway Mucus Viscoelasticity and Slow Mucus Particle Transit.
    American journal of respiratory cell and molecular biology, 2021, Volume: 64, Issue:1

    Topics: Adult; Airway Obstruction; Extracellular Traps; Humans; Mucus; Neutrophils; Oxidative Stress; Peroxi

2021
Assisting PNA transport through cystic fibrosis human airway epithelia with biodegradable hybrid lipid-polymer nanoparticles.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Airway Obstruction; Cystic Fibrosis; Cystic Fibrosis Transmembra

2021
Eosinophil Extracellular Traps in the Casts of Plastic Bronchitis Associated With Influenza Virus Infection.
    Chest, 2021, Volume: 160, Issue:3

    Topics: Airway Obstruction; Asthma; Bronchitis; Cell Aggregation; Cell Death; Child; Chromatin; Eosinophils;

2021
VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway.
    Developmental cell, 2021, 06-07, Volume: 56, Issue:11

    Topics: Airway Obstruction; Animals; Cell Transdifferentiation; Disease Models, Animal; Gene Expression Regu

2021
Association of Standardized Tracheostomy Care Protocol Implementation and Reinforcement With the Prevention of Life-Threatening Respiratory Events.
    JAMA otolaryngology-- head & neck surgery, 2018, Jun-01, Volume: 144, Issue:6

    Topics: Airway Obstruction; Clinical Protocols; Female; Humans; Male; Middle Aged; Mucus; North Carolina; Re

2018
Persistent Atelectasis in a Patient With Cystic Fibrosis: Are Antibiotics Always Needed?
    Archivos de bronconeumologia, 2019, Volume: 55, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Airway Obstruction; Anti-Bacterial Agents; Antifungal Agents; C

2019
Rabbit's ears sign: Mucoid impaction in bronchi.
    Journal of medical imaging and radiation oncology, 2018, Volume: 62 Suppl 1

    Topics: Airway Obstruction; Bronchi; Diagnosis, Differential; Humans; Mucus; Tomography, X-Ray Computed

2018
Plugs of the air passages.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2018, 10-16, Volume: 138, Issue:16

    Topics: Adult; Airway Obstruction; Bronchitis; Bronchoscopy; Female; Humans; Mucus

2018
Targeting of cathepsin S reduces cystic fibrosis-like lung disease.
    The European respiratory journal, 2019, Volume: 53, Issue:3

    Topics: Airway Obstruction; Animals; Cathepsins; Cystic Fibrosis; Disease Models, Animal; Epithelial Sodium

2019
CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma.
    Chest, 2019, Volume: 155, Issue:6

    Topics: Airway Management; Airway Obstruction; Asthma; Biomarkers; Correlation of Data; Eosinophils; Female;

2019
A Single Center Experience of Feasibility of a Novel Self-Expanding Metallic Airway Stent (Bonastent): A Case Series.
    Journal of bronchology & interventional pulmonology, 2019, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Alloys; Bronchi; Bronchoscopy; Cohort Studies; F

2019
Obstructive inflammatory tracheal pseudomembrane.
    Archivos de bronconeumologia, 2013, Volume: 49, Issue:9

    Topics: Aged; Airway Obstruction; Anti-Inflammatory Agents; Bronchi; Combined Modality Therapy; Cough; Exuda

2013
Beware of gloved fingers.
    Annals of the American Thoracic Society, 2013, Volume: 10, Issue:1

    Topics: Aged; Airway Obstruction; Bronchoscopy; Carcinoma, Squamous Cell; Diagnosis, Differential; Fatal Out

2013
Removal of endotracheal tube obstruction with a secretion clearance device.
    Respiratory care, 2014, Volume: 59, Issue:9

    Topics: Aged; Airway Obstruction; Catheters; Equipment Failure; Female; Humans; Intubation, Intratracheal; M

2014
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
    American journal of respiratory and critical care medicine, 2014, May-01, Volume: 189, Issue:9

    Topics: Airway Obstruction; Animals; Bronchiectasis; Cystic Fibrosis; Disease Models, Animal; Epithelial Sod

2014
Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.
    American journal of respiratory cell and molecular biology, 2014, Volume: 51, Issue:5

    Topics: Airway Obstruction; Animals; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Dehydration; Genomics; M

2014
Mucus plugging mimicking a left hilar mass.
    British journal of hospital medicine (London, England : 2005), 2014, Volume: 75, Issue:9

    Topics: Airway Obstruction; Asthma; Diagnosis, Differential; Humans; Lung; Lung Neoplasms; Male; Middle Aged

2014
Nebulised N-acetylcysteine used in acute tracheostoma obstruction.
    The Journal of laryngology and otology, 2014, Volume: 128, Issue:12

    Topics: Acetylcysteine; Aged; Airway Obstruction; Drug Therapy, Combination; Expectorants; Female; Humans; L

2014
Fatal endotracheal tube obstruction due to the ball valve effect.
    BMJ case reports, 2015, Jan-23, Volume: 2015

    Topics: Aged; Airway Obstruction; Equipment Failure; Fatal Outcome; Humans; Intubation, Intratracheal; Male;

2015
Recombinant human deoxyribonuclease therapy improves airway resistance and reduces DNA extracellular traps in a murine acute asthma model.
    Experimental lung research, 2016, Volume: 42, Issue:2

    Topics: Administration, Intranasal; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Bronc

2016
Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma.
    The Journal of clinical investigation, 2016, 06-01, Volume: 126, Issue:6

    Topics: Airway Obstruction; Asthma; Case-Control Studies; Gels; Humans; Mucin 5AC; Mucin-5B; Mucociliary Cle

2016
A 4-year-old child presenting morning onset of spontaneous tracheal rupture due to bronchial mucous plug occlusion during the nighttime sleep: a case report.
    Journal of medical case reports, 2016, Jun-01, Volume: 10, Issue:1

    Topics: Airway Obstruction; Bronchial Diseases; Bronchoscopy; Child, Preschool; Humans; Male; Mediastinal Em

2016
Not all mucous plugs are created equal!
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Abdominal Wall; Airway Obstruction; Catheters; Equipment Failure; Female; Fundoplication; Hernias, D

2017
Increased mucus accumulation in horses chronically affected with recurrent airway obstruction is not associated with up-regulation of CLCA1, EGFR, MUC5AC, Bcl-2, IL-13 and INF-gamma expression.
    Veterinary immunology and immunopathology, 2008, Sep-15, Volume: 125, Issue:1-2

    Topics: Airway Obstruction; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Cell Count; Chloride

2008
[Effects of manually assisted coughing on respiratory mechanics in patients requiring full ventilatory support].
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2008, Volume: 34, Issue:6

    Topics: Adult; Aged; Airway Obstruction; Cough; Female; Humans; Intubation, Intratracheal; Male; Middle Aged

2008
Ventilation patterns influence airway secretion movement.
    Respiratory care, 2008, Volume: 53, Issue:10

    Topics: Airway Obstruction; Humans; Models, Biological; Mucus; Respiration, Artificial; Suction

2008
Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma.
    International immunology, 2009, Volume: 21, Issue:6

    Topics: Airway Obstruction; Allergens; Animals; Apoptosis; Asthma; Cell Adhesion; Cytokines; Disease Models,

2009
Delayed endotracheal tube obstruction by mucus plug in a child.
    Chinese medical journal, 2009, Apr-05, Volume: 122, Issue:7

    Topics: Airway Obstruction; Child; Humans; Intubation, Intratracheal; Male; Mucus

2009
Thoracic air leakage in the presentation of cast bronchitis.
    Chest, 2009, Volume: 136, Issue:2

    Topics: Adrenal Cortex Hormones; Airway Obstruction; Bronchitis; Bronchoscopy; Child, Preschool; Drainage; F

2009
Bronchial casts and pandemic (H1N1) 2009 virus infection.
    Emerging infectious diseases, 2010, Volume: 16, Issue:2

    Topics: Airway Obstruction; Child; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Male; M

2010
Mucus hypersecretion in COPD: should we only rely on symptoms?
    European respiratory review : an official journal of the European Respiratory Society, 2010, Volume: 19, Issue:116

    Topics: Airway Obstruction; Cough; Humans; Mucus; Pulmonary Disease, Chronic Obstructive

2010
Experience with a new device for clearing mucus from the endotracheal tube.
    Respiratory care, 2011, Volume: 56, Issue:4

    Topics: Adult; Aged, 80 and over; Airway Obstruction; Device Removal; Humans; Intubation, Intratracheal; Mal

2011
In vivo monitoring of cystic fibrosis-like lung disease in mice by volumetric computed tomography.
    The European respiratory journal, 2011, Volume: 38, Issue:5

    Topics: Airway Obstruction; Animals; Bronchography; Cone-Beam Computed Tomography; Cystic Fibrosis; Disease

2011
Muc5b is the major polymeric mucin in mucus from thoroughbred horses with and without airway mucus accumulation.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Airway Obstruction; Animals; Antibodies; Bacteria; Horse Diseases; Horses; Immune Sera; Inflammation

2011
Do commonly used ventilator settings for mechanically ventilated adults have the potential to embed secretions or promote clearance?
    Respiratory care, 2011, Volume: 56, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Female; Humans; Inspiratory Capacity; Male; Midd

2011
Potentially lethal complications of tracheostomy: autopsy considerations.
    The American journal of forensic medicine and pathology, 2011, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Airway Obstruction; Equipment Failure; Female; Forensic Pathology; Hemorrhage; Hu

2011
Practical aspects of oronasopharyngeal suction in children.
    Nursing children and young people, 2011, Volume: 23, Issue:7

    Topics: Adolescent; Airway Obstruction; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Mucus; Nur

2011
Correlation and discriminant analysis between clinical, endoscopic, thoracic X-ray and bronchoalveolar lavage fluid cytology scores, for staging horses with recurrent airway obstruction (RAO).
    Research in veterinary science, 2012, Volume: 93, Issue:2

    Topics: Airway Obstruction; Animals; Cough; Horse Diseases; Horses; Mucus; Pulmonary Disease, Chronic Obstru

2012
Respiratory infections increase the risk of granulation tissue formation following airway stenting in patients with malignant airway obstruction.
    Chest, 2012, Volume: 141, Issue:6

    Topics: Adolescent; Adult; Airway Obstruction; Bronchoscopy; Equipment Failure; Female; Foreign-Body Migrati

2012
Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.
    Physiological genomics, 2012, Apr-15, Volume: 44, Issue:8

    Topics: Airway Obstruction; Animals; Disease Models, Animal; Epithelial Sodium Channels; Lung Diseases, Obst

2012
Lack of humidification may harm the patient during continuous positive airway pressure.
    British journal of anaesthesia, 2012, Volume: 108, Issue:5

    Topics: Aged; Airway Obstruction; Continuous Positive Airway Pressure; Humans; Humidity; Male; Mucus; Respir

2012
Failure of both suction catheter passage and bronchoscopy to diagnose an obstructing tracheal mucus plug.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2012, Volume: 59, Issue:9

    Topics: Airway Obstruction; Bronchoscopy; Catheterization; Humans; Male; Middle Aged; Mucus; Suction; Trache

2012
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:10

    Topics: 3' Untranslated Regions; Airway Obstruction; Animals; Antiporters; Asthma; Bronchitis; Calcium; Chil

2012
CT evaluation of airway foreign bodies in children: emphasis on the delayed diagnosis and differentiation from airway mucus plugs.
    Japanese journal of radiology, 2013, Volume: 31, Issue:1

    Topics: Airway Obstruction; Bronchoscopy; Child, Preschool; Diagnosis, Differential; Female; Foreign Bodies;

2013
Images in clinical medicine. Mucous plug in the bronchus causing lung collapse.
    The New England journal of medicine, 2002, Oct-03, Volume: 347, Issue:14

    Topics: Aged; Airway Obstruction; Bronchi; Bronchial Diseases; Bronchiectasis; Bronchoscopy; Female; Humans;

2002
Plastic bronchitis mimicking foreign body aspiration that needs a specific diagnostic procedure.
    Intensive care medicine, 2003, Volume: 29, Issue:2

    Topics: Acute Disease; Airway Obstruction; Bronchi; Bronchitis; Bronchoscopy; Causality; Child, Preschool; C

2003
Mucin genes in horse airways: MUC5AC, but not MUC2, may play a role in recurrent airway obstruction.
    Equine veterinary journal, 2003, Volume: 35, Issue:3

    Topics: Airway Obstruction; Animals; Female; Gene Expression; Horse Diseases; Horses; Lung; Male; Mucin 5AC;

2003
Transfer for "pneumonia".
    Pediatric emergency care, 2003, Volume: 19, Issue:3

    Topics: Airway Obstruction; Bronchial Spasm; Bronchiolitis; Diagnostic Errors; Emergencies; Emergency Servic

2003
Influence of the rheological properties of airway mucus on cough sound generation.
    Respirology (Carlton, Vic.), 2003, Volume: 8, Issue:1

    Topics: Adult; Airway Obstruction; Case-Control Studies; Chronic Disease; Cough; Female; Humans; Male; Middl

2003
Characterization of airway plugging in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Asthma; Bronchi; Cell Culture Techniques; Child; Humans

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
The role of mucus in fatal asthma.
    The American journal of medicine, 2003, Volume: 115, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchi; Humans; Mucins; Mucus; Muscle, Smooth

2003
[Recurrent manifestations of bronchial obstruction by voluminous mucus plugs].
    Journal francais de medecine et chirurgie thoraciques, 1958, Volume: 12, Issue:2

    Topics: Airway Obstruction; Bronchi; Bronchial Diseases; Casts, Surgical; Disease; Humans; Mucus

1958
[Bronchial obstruction caused by mucus plug: lobectomy].
    Acta chirurgica Belgica, 1959, Volume: 58, Issue:1

    Topics: Airway Obstruction; Blood Pressure; Bronchi; Bronchial Diseases; Disease; Humans; Mucus; Pneumonecto

1959
Mucus and fatal asthma.
    The American journal of medicine, 2004, Jan-01, Volume: 116, Issue:1

    Topics: Airway Obstruction; Asthma; Cell Count; Goblet Cells; Humans; Mucin 5AC; Mucin-5B; Mucins; Mucus; Re

2004
Breath condensate hydrogen peroxide correlates with both airway cytology and epithelial lining fluid ascorbic acid concentration in the horse.
    Free radical research, 2004, Volume: 38, Issue:2

    Topics: Airway Obstruction; Animals; Ascorbic Acid; Breath Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy

2004
Total airway obstruction by a mucous plug relieved with extreme positive pressure: case report of a pediatric patient.
    Journal of emergency nursing, 2004, Volume: 30, Issue:5

    Topics: Airway Obstruction; Humans; Infant; Male; Mucus; Positive-Pressure Respiration

2004
[Severe asthma complicated with large mucoid impaction: successful removal with balloon catheter].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:10

    Topics: Adult; Airway Obstruction; Asthma; Bronchoscopy; Catheterization; Female; Humans; Kidney Transplanta

2004
[Concentrations of carcinoembryonic antigen in serum and bronchoalveolar lavage fluid of asthmatic patients with mucoid impaction].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:12

    Topics: Aged; Airway Obstruction; Asthma; Bronchial Diseases; Bronchiectasis; Bronchoalveolar Lavage Fluid;

2004
Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma.
    International archives of allergy and immunology, 2005, Volume: 138, Issue:3

    Topics: Airway Obstruction; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchoalveolar Lavage Fluid;

2005
[Intermittent asphyxia syndrome caused by a bronchial cast in the subglottic region].
    Archivos de bronconeumologia, 2005, Volume: 41, Issue:11

    Topics: Airway Obstruction; Asphyxia; Bronchi; Female; Glottis; Humans; Middle Aged; Mucus; Syndrome

2005
Pressure-flow signatures of central-airway mucus plugging.
    Critical care medicine, 2006, Volume: 34, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Airway Obstruction; Airway Resistance; Anti-Bacterial Agents; Bronch

2006
Persistent mucus accumulation: a consequence of delayed bronchial mucous cell apoptosis in RAO-affected horses?
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:4

    Topics: Airway Obstruction; Animals; Apoptosis; Bronchi; Bronchoalveolar Lavage Fluid; Horse Diseases; Horse

2006
The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model.
    Experimental & molecular medicine, 2006, Apr-30, Volume: 38, Issue:2

    Topics: Acetates; Airway Obstruction; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Cyclopropanes; Cyste

2006
Pulmonary atelectasis manifested after induction of anesthesia: a contribution of sinobronchial syndrome?
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Adult; Airway Obstruction; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Blood

2007
A new link to airway obstruction in asthma.
    Nature medicine, 2007, Volume: 13, Issue:7

    Topics: Airway Obstruction; Asthma; gamma-Aminobutyric Acid; Humans; Mucus; Respiratory System; Signal Trans

2007
Bronchoscopic removal of mucus casts in a boy with plastic bronchitis.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:9

    Topics: Airway Obstruction; Bronchitis; Bronchoscopy; Diagnosis, Differential; Foreign Bodies; Humans; Infan

2007
Airway clearance: physiology, pharmacology, techniques, and practice.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Expectorants; Humans; Mucus; Physical Therapy Modalities; Respiratory Therapy

2007
Airway clearance: physiology, pharmacology, techniques, and practice.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Expectorants; Humans; Mucus; Physical Therapy Modalities; Respiratory Therapy

2007
Airway clearance: physiology, pharmacology, techniques, and practice.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Expectorants; Humans; Mucus; Physical Therapy Modalities; Respiratory Therapy

2007
Airway clearance: physiology, pharmacology, techniques, and practice.
    Respiratory care, 2007, Volume: 52, Issue:10

    Topics: Airway Obstruction; Expectorants; Humans; Mucus; Physical Therapy Modalities; Respiratory Therapy

2007
Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.
    American journal of respiratory cell and molecular biology, 2008, Volume: 39, Issue:1

    Topics: Adenoviridae; Adenoviridae Infections; Airway Obstruction; Animals; Cell Culture Techniques; Cell Di

2008
Chronic airflow obstruction: pathophysiology and management.
    Comprehensive therapy, 1980, Volume: 6, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Airway Obstruction; Atropine; Blood Gas Analysis;

1980
Mucus hypersecretion, airways obstruction, and mortality from chronic lung disease.
    Lancet (London, England), 1984, Feb-11, Volume: 1, Issue:8372

    Topics: Airway Obstruction; Humans; Lung Diseases, Obstructive; Mucus; Respiratory Function Tests; Smoking

1984
Mucus hypersecretion, airways obstruction.
    Lancet (London, England), 1984, Apr-07, Volume: 1, Issue:8380

    Topics: Adult; Airway Obstruction; Ciliary Motility Disorders; Humans; Mucus; Smoking

1984
Mast cells and asthma. The role of mast cell mediators in the pathogenesis of allergic asthma.
    Annals of allergy, 1983, Volume: 51, Issue:1 Pt 1

    Topics: Airway Obstruction; Asthma; Bradykinin; Capillary Permeability; Histamine; Humans; Leukotriene E4; M

1983
The "mucous plug syndrome". A pulmonary embolism mimic.
    Clinical nuclear medicine, 1984, Volume: 9, Issue:9

    Topics: Adult; Airway Obstruction; Bronchi; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Mucu

1984
Neonatal high-frequency jet ventilation.
    Pediatrics, 1983, Volume: 72, Issue:1

    Topics: Airway Obstruction; Bronchial Fistula; Fistula; Humans; Infant, Newborn; Mucus; Pleural Diseases; Pu

1983
Regional mucociliary removal of inhaled particles in smokers with small airways disease.
    Respiration; international review of thoracic diseases, 1983, Volume: 44, Issue:5

    Topics: Adult; Aerosols; Airway Obstruction; Cilia; Humans; Lung Diseases, Obstructive; Microspheres; Middle

1983
Mucous plugging simulating pulmonary embolism in patients with quadriplegia.
    Chest, 1984, Volume: 85, Issue:3

    Topics: Adult; Airway Obstruction; Bronchial Diseases; Diagnosis, Differential; Humans; Hypoxia; Lung; Male;

1984
Mucus in the bronchi and respiratory pathophysiology.
    European journal of respiratory diseases. Supplement, 1980, Volume: 111

    Topics: Airway Obstruction; Bronchi; Humans; Mucus; Respiratory Tract Diseases

1980
Membranous laryngotracheobronchitis.
    Pediatrics, 1982, Volume: 70, Issue:5

    Topics: Airway Obstruction; Child; Croup; Diagnosis, Differential; Endoscopy; Female; Foreign Bodies; Humans

1982
Tracheobronchial mucus: abnormalities related to asthma and its treatment.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1981, Volume: 18, Issue:1

    Topics: Airway Obstruction; Animals; Asthma; Biological Transport; Bronchi; Cilia; Constriction, Pathologic;

1981
Sleep hypoxemia. Growing clinical awareness.
    Colorado medicine, 1980, Volume: 77, Issue:1

    Topics: Airway Obstruction; Humans; Hypoxia; Mucus; Obesity; Respiration Disorders; Sleep; Sleep Apnea Syndr

1980
Rapid reocclusion of left primary bronchus by fibrinomucinous cast in a case of large cell lung cancer.
    Southern medical journal, 1995, Volume: 88, Issue:4

    Topics: Airway Obstruction; Bronchi; Bronchoscopy; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; L

1995
Massive atelectasis with respiratory arrest due to transtracheal oxygen catheter-related mass formation.
    Chest, 1994, Volume: 106, Issue:3

    Topics: Aged; Airway Obstruction; Catheters, Indwelling; Humans; Male; Mucus; Oxygen Inhalation Therapy; Pul

1994
Acoustic method to estimate the longitudinal area profile of endotracheal tubes.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Acoustics; Airway Obstruction; Evaluation Studies as Topic; Humans; Intubation, Intratracheal; Linea

1994
A nearly fatal tracheal obstruction resulting from a transtracheal oxygen catheter.
    Chest, 1993, Volume: 104, Issue:5

    Topics: Aged; Airway Obstruction; Catheters, Indwelling; Equipment Failure; Humans; Male; Mucus; Oxygen Inha

1993
Fontan's operation complications.
    Pediatric cardiology, 1993, Volume: 14, Issue:1

    Topics: Airway Obstruction; Child, Preschool; Female; Heart Atria; Humans; Mucus; Postoperative Complication

1993
[Dangerous complication of transtracheal oxygen therapy with the SCOOP(R) system].
    Pneumologie (Stuttgart, Germany), 1996, Volume: 50, Issue:10

    Topics: Aged; Airway Obstruction; Bronchoscopy; Catheters, Indwelling; Equipment Failure; Female; Humans; In

1996
Obliterative bronchiolitis: individual CT signs of small airways disease and functional correlation.
    Radiology, 1997, Volume: 203, Issue:3

    Topics: Adult; Aged; Airway Obstruction; Bronchi; Bronchiolitis Obliterans; Bronchography; Female; Forced Ex

1997
Mucoid impaction following nasal intubation in a child with an upper respiratory infection.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:4

    Topics: Airway Obstruction; Bronchoscopy; Child, Preschool; Fiber Optic Technology; Humans; Intubation, Gast

1998
Inspissated secretions: a life-threatening complication of prolonged noninvasive ventilation.
    Respiratory care, 2000, Volume: 45, Issue:5

    Topics: Aged; Airway Obstruction; Humans; Laryngoscopy; Male; Mouth Mucosa; Mucus; Pharynx; Positive-Pressur

2000
Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.
    The Journal of experimental medicine, 2000, Jul-17, Volume: 192, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Airway Obstruction; Animals; Bronchoalveolar Lavage Fluid; Eosinophi

2000
Tracheobronchial mucus viscoelasticity during environmental challenge in horses with recurrent airway obstruction.
    Equine veterinary journal, 2000, Volume: 32, Issue:5

    Topics: Airway Obstruction; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chronic Disease; Horse Diseases;

2000
Mucus plugging as a cause of acute lobar overdistension.
    Pediatric emergency care, 2001, Volume: 17, Issue:1

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchoscopy; Child, Preschool; Cough; Diagnosis, Differe

2001
[Plastic bronchitis and mucoid impaction--uncommon disease syndromes with expectoration mucus plugs].
    Pneumonologia i alergologia polska, 2001, Volume: 69, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Aspergillosis, Allergic Bronchopulmonary; Asthma

2001
Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates.
    Pediatrics, 2001, Volume: 108, Issue:2

    Topics: Administration, Inhalation; Airway Obstruction; Deoxyribonuclease I; Expectorants; Humans; Infant, N

2001
Persistent mucin glycoprotein alterations in equine recurrent airway obstruction.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:3

    Topics: Airway Obstruction; Animals; Blood; Bronchoalveolar Lavage Fluid; Dialysis; Enzyme-Linked Immunosorb

2001
Histopathology of fatal asthma: drowning in mucus.
    Pediatric pulmonology, 2001, Volume: Suppl 23

    Topics: Adolescent; Adult; Airway Obstruction; Asthma; Drowning; Female; Humans; Male; Middle Aged; Mucus

2001
Atelectasis and mucus plugging in spinal cord injury: case report and therapeutic approaches.
    The journal of spinal cord medicine, 2001,Winter, Volume: 24, Issue:4

    Topics: Acetylcysteine; Airway Obstruction; Bronchodilator Agents; Bronchoscopy; Combined Modality Therapy;

2001
British phlegm, British bronchi.
    Lancet (London, England), 1977, Feb-19, Volume: 1, Issue:8008

    Topics: Adult; Airway Obstruction; Bronchi; Bronchitis; Diagnosis, Differential; Humans; Male; Middle Aged;

1977
[Tracheobronchial care in the newborn infant--aid to the nurse].
    Tijdschrift voor ziekenverpleging, 1979, Jul-03, Volume: 32, Issue:14

    Topics: Aerosols; Airway Obstruction; Humans; Infant, Newborn; Mucus; Physical Therapy Modalities; Posture;

1979
[Inter-alpha-trypsin inhibitor in serum and bronchial mucus inhibitor in sputum in chronic airway obstruction (author's transl)].
    Respiration; international review of thoracic diseases, 1978, Volume: 36, Issue:1

    Topics: Airway Obstruction; alpha 1-Antitrypsin; Bronchi; Chronic Disease; Humans; Lung Diseases, Obstructiv

1978
Large bronchial casts.
    Archives of internal medicine, 1979, Volume: 139, Issue:5

    Topics: Adult; Airway Obstruction; Bronchi; Bronchoscopy; Fiber Optic Technology; Hemorrhage; Humans; Male;

1979
Mucoid impaction (inspissated secretions) in segmental bronchial obstruction.
    Radiology, 1979, Volume: 133, Issue:1

    Topics: Adenoma; Airway Obstruction; Bronchi; Bronchial Diseases; Bronchial Neoplasms; Bronchopulmonary Sequ

1979
[Conclusions of an international symposium held at Aachen on 4 and 5 May about mucolytic agents, especially oral acetylcysteine].
    Revue de l'Institut d'hygiene des mines, 1979, Volume: 34, Issue:3

    Topics: Acetylcysteine; Airway Obstruction; Bronchi; Evaluation Studies as Topic; Expectorants; Humans; Mucu

1979
Acetylcysteine for life-threatening acute bronchial obstruction.
    Annals of internal medicine, 1978, Volume: 88, Issue:5

    Topics: Acetylcysteine; Acute Disease; Adult; Airway Obstruction; Bronchial Diseases; Female; Humans; Male;

1978
[Bronchial obstruction by mucoid impaction--a frequent cause of atelectasis (author's transl)].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1978, Volume: 150, Issue:1

    Topics: Adult; Airway Obstruction; Child; Female; Humans; Lung; Mucus; Penicillins; Pulmonary Atelectasis; R

1978
The natural history of chronic airflow obstruction.
    British medical journal, 1977, Jun-25, Volume: 1, Issue:6077

    Topics: Adult; Age Factors; Airway Obstruction; Bronchial Diseases; Chronic Disease; Forced Expiratory Volum

1977
Treatment of mucus hypersecretion in human disease.
    Advances in experimental medicine and biology, 1977, Volume: 89

    Topics: Airway Obstruction; Atropine; Bronchial Diseases; Cystic Fibrosis; Exudates and Transudates; Glycopr

1977
Bronchorrhea responsive to aerosolized atropine.
    JAMA, 1976, Mar-29, Volume: 235, Issue:13

    Topics: Aerosols; Airway Obstruction; Atropine; Bronchi; Humans; Male; Middle Aged; Mucus; Secretory Rate

1976
Bronchocentric granulomatosis, mucoid impaction, and hypersensitivity reactions to fungi.
    The American review of respiratory disease, 1975, Volume: 111, Issue:4

    Topics: Airway Obstruction; Aspergillosis; Aspergillus fumigatus; Bronchi; Bronchial Diseases; Eosinophils;

1975
Tracheal mucociliary transport in patients with cystic fibrosis and its stimulation by terbutaline.
    The American review of respiratory disease, 1975, Volume: 111, Issue:6

    Topics: Adolescent; Adult; Airway Obstruction; Bronchoscopy; Cilia; Cystic Fibrosis; Female; Humans; Male; M

1975
Mucoid impaction of the bronchi. Case reports.
    Missouri medicine, 1975, Volume: 72, Issue:8

    Topics: Adult; Airway Obstruction; Bronchial Diseases; Diagnosis, Differential; Humans; Male; Mucus; Radiogr

1975
Familial non-cystic fibrosis mucus inspissation of respiratory tract.
    Archives of disease in childhood, 1975, Volume: 50, Issue:9

    Topics: Airway Obstruction; Ampicillin; Bronchitis; Bronchopneumonia; Child; Child, Preschool; Chronic Disea

1975
Chronic bronchitis.
    The Practitioner, 1975, Volume: 215, Issue:1290

    Topics: Airway Obstruction; Bronchitis; Environmental Pollution; Humans; Mucus; Smoking

1975
Contribution of morphometry, bronchial casts and electron microscopy to study of airway obstruction in chronic obstructive lung disease.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69, Issue:2

    Topics: Airway Obstruction; Bronchi; Humans; Lung Diseases, Obstructive; Mucus

1976
Airway mucous plug mimicking diaphragmatic herniation.
    Anaesthesia, 1992, Volume: 47, Issue:2

    Topics: Airway Obstruction; Diagnosis, Differential; Hernia, Diaphragmatic, Traumatic; Humans; Male; Middle

1992
Acute respiratory compromise resulting from tracheal mucous impaction secondary to a transtracheal oxygen catheter.
    Chest, 1992, Volume: 101, Issue:5

    Topics: Acute Disease; Aged; Airway Obstruction; Female; Humans; Intubation, Intratracheal; Mucus; Oxygen In

1992
Airway obstruction by a mucus ball from a transtracheal oxygen catheter.
    Chest, 1992, Volume: 101, Issue:6

    Topics: Adult; Airway Obstruction; Catheterization; Female; Humans; Intubation, Intratracheal; Mucus; Oxygen

1992
Airway obstruction by a mucus ball from a transtracheal oxygen catheter.
    Chest, 1992, Volume: 101, Issue:6

    Topics: Airway Obstruction; Catheterization; Humans; Intubation, Intratracheal; Mucus; Oxygen Inhalation The

1992
Respiratory failure and cor pulmonale associated with tracheal mucoid accumulation from a SCOOP transtracheal oxygen catheter.
    Chest, 1992, Volume: 101, Issue:2

    Topics: Airway Obstruction; Female; Humans; Intubation, Intratracheal; Male; Middle Aged; Mucus; Oxygen; Pul

1992
Chronic inflammation is associated with an increased proportion of goblet cells recovered by bronchial lavage.
    Chest, 1991, Volume: 100, Issue:2

    Topics: Airway Obstruction; Bronchi; Bronchitis; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Chr

1991
Transient unilateral hyperlucent lung due to mucus plugs.
    Intensive care medicine, 1991, Volume: 17, Issue:2

    Topics: Airway Obstruction; Female; Humans; Humidity; Lung; Middle Aged; Mucus; Radiography; Tracheostomy

1991
Nearly fatal partial obstruction of the upper airway.
    Postgraduate medicine, 1990, Feb-01, Volume: 87, Issue:2

    Topics: Adult; Airway Obstruction; Asthma; Bronchi; Female; Histamine H1 Antagonists; Humans; Mucus; Nonpres

1990
Eosinophil cationic protein stimulates and major basic protein inhibits airway mucus secretion.
    The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:3

    Topics: Airway Obstruction; Animals; Asthma; Blood Proteins; Cats; Dose-Response Relationship, Drug; Enzyme-

1991
Relevance of airflow obstruction and mucus hypersecretion to mortality.
    Respiratory medicine, 1991, Volume: 85, Issue:1

    Topics: Airway Obstruction; Cause of Death; Coronary Disease; Follow-Up Studies; Forced Expiratory Volume; G

1991
Immediate postextubation upper airway obstruction by a mucous cast.
    Critical care medicine, 1990, Volume: 18, Issue:7

    Topics: Adolescent; Airway Obstruction; Bronchoscopy; Female; Humans; Intubation, Intratracheal; Mucus

1990
Characterization of airway mucus from a fatal case of status asthmaticus.
    Pediatric pulmonology, 1988, Volume: 5, Issue:3

    Topics: Adolescent; Airway Obstruction; Asthma; Centrifugation, Density Gradient; Chromatography, Thin Layer

1988
Regulation of airway secretions.
    Chest, 1985, Volume: 87, Issue:1 Suppl

    Topics: Airway Obstruction; Asthma; Biological Transport; Epithelium; Humans; Ion Channels; Mucus; Respirato

1985
Insidious onset of airway obstruction of an endotracheal tube by blood-mucus plugs.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1989, Volume: 27, Issue:3

    Topics: Adult; Airway Obstruction; Blood Coagulation; Humans; Intubation, Intratracheal; Male; Mucus

1989
Mucus transport in a miniaturized simulated cough machine: effect of constriction and serous layer simulant.
    Biorheology, 1989, Volume: 26, Issue:6

    Topics: Airway Obstruction; Airway Resistance; Biological Transport; Cough; Humans; Models, Biological; Mucu

1989
Shortlasting unilateral neuralgiform headache attacks with conjunctival injection, tearing, sweating, and rhinorrhea.
    Cephalalgia : an international journal of headache, 1989, Volume: 9, Issue:2

    Topics: Aged; Airway Obstruction; Cluster Headache; Conjunctival Diseases; Humans; Male; Middle Aged; Mucus;

1989
Reversible acute unilateral diminished pulmonary ventilation and perfusion caused by a mucous plug.
    American journal of physiologic imaging, 1989, Volume: 4, Issue:2

    Topics: Aged; Airway Obstruction; Angiography; Bronchoscopy; Diagnosis, Differential; Humans; Lung; Male; Mu

1989
Asphyxiation by glottic impaction of nasal secretions.
    The American journal of forensic medicine and pathology, 1989, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Airway Obstruction; Asphyxia; Female; Glottis; Humans; Mucus; Nasopharynx

1989
Profound intraoperative atelectasis.
    British journal of anaesthesia, 1989, Volume: 62, Issue:2

    Topics: Adult; Airway Obstruction; Femoral Fractures; Humans; Hypoxia; Intraoperative Complications; Male; M

1989
Physiologic implications of the autonomic aberrations in cystic fibrosis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:4

    Topics: Adult; Airway Obstruction; Airway Resistance; Asthma; Autonomic Nervous System; Bronchi; Bronchial P

1986
Tracheal plugs in oligohydramnios.
    American journal of perinatology, 1988, Volume: 5, Issue:3

    Topics: Airway Obstruction; Amniotic Fluid; Diagnosis, Differential; Female; Fetal Distress; Humans; Infant,

1988
A case of plastic bronchitis.
    Journal of the Royal Society of Medicine, 1988, Volume: 81, Issue:6

    Topics: Airway Obstruction; Bronchitis; Female; Humans; Middle Aged; Mucus; Suction

1988
Obstructive emphysema due to mucus plugging in quadriplegia.
    Archives of physical medicine and rehabilitation, 1987, Volume: 68, Issue:5 Pt 1

    Topics: Adult; Airway Obstruction; Bronchoscopy; Emphysema; Humans; Male; Mucus; Quadriplegia; Suction; Ther

1987
The presence or absence of bronchial mucus in fatal asthma.
    The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:3 Pt 2

    Topics: Airway Obstruction; Asthma; Bronchi; Humans; Mucus

1987
The pathogenesis of severe asthma: a consensus report from the Workshop on Pathogenesis.
    The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:3 Pt 2

    Topics: Acute Disease; Airway Obstruction; Asthma; Bronchial Spasm; Humans; Lung; Mast Cells; Mucus; Pulmona

1987
Occluded trach tube.
    Nursing, 1987, Volume: 17, Issue:4

    Topics: Airway Obstruction; Emergencies; Humans; Mucus; Postoperative Complications; Tracheotomy

1987
Unilateral pulmonary hyperinflation from mucus check-valve mechanism.
    Critical care medicine, 1986, Volume: 14, Issue:9

    Topics: Adult; Airway Obstruction; Bronchi; Humans; Lung Diseases; Male; Mucus; Respiration; Suction; Therap

1986
Unilateral absence of ventilation and perfusion associated with a bronchial mucous plug.
    Southern medical journal, 1987, Volume: 80, Issue:3

    Topics: Adult; Airway Obstruction; Bronchi; Female; Humans; Lung; Mucus; Paraplegia; Radiography; Radionucli

1987
Excessive accumulation of mucus in children with asthma: a potential role for erythromycin? A case discussion.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:2

    Topics: Airway Obstruction; Asthma; Child, Preschool; Erythromycin; Glucocorticoids; Humans; Male; Mucus; Re

1986
Nasal obstruction.
    Postgraduate medicine, 1972, Volume: 52, Issue:2

    Topics: Adenoids; Airway Obstruction; Ephedrine; Foreign Bodies; Hematoma; Histamine H1 Antagonists; Humans;

1972
The contribution of morphology to the study of chronic obstructive lung disease.
    The American journal of medicine, 1974, Volume: 57, Issue:3

    Topics: Adult; Age Factors; Aged; Airway Obstruction; Biopsy; Bronchi; Bronchitis; Cilia; Exudates and Trans

1974
[Letter: Mucoid impactation of the bronchi].
    Orvosi hetilap, 1974, Dec-22, Volume: 115, Issue:51

    Topics: Airway Obstruction; Bronchi; Humans; Mucus; Pulmonary Atelectasis

1974
Criteria for the testing of mucolytic agents.
    Scandinavian journal of respiratory diseases. Supplementum, 1974, Volume: 90

    Topics: Airway Obstruction; Bronchitis; Chronic Disease; Circadian Rhythm; Expectorants; Humans; Mucus; Neur

1974
Rare complications of bronchial asthma.
    The Journal of asthma research, 1972, Volume: 10, Issue:2

    Topics: Adult; Aged; Airway Obstruction; Allergens; Asthma; Bronchial Neoplasms; Bronchiectasis; Bronchitis;

1972
[Effect of a bronchosecretolytic agent on the tracheobronchial expectoration].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:10

    Topics: Airway Obstruction; Animals; Bronchi; Bronchodilator Agents; Cilia; Cricetinae; Epithelium; Expector

1972
Disease of the small airways in chronic bronchitis.
    The American review of respiratory disease, 1973, Volume: 107, Issue:4

    Topics: Airway Obstruction; Airway Resistance; Autopsy; Bronchi; Bronchitis; Chronic Disease; Humans; Method

1973
RPC from the AFIP.
    Radiology, 1973, Volume: 108, Issue:1

    Topics: Adenoma; Adult; Airway Obstruction; Arteriovenous Fistula; Bronchi; Bronchial Diseases; Carcinoma, B

1973
Mucoid inpaction of the bronchus. Diagnosis and treatment.
    The American review of respiratory disease, 1973, Volume: 108, Issue:4

    Topics: Acetylcysteine; Adult; Airway Obstruction; Asthma; Bronchial Diseases; Bronchitis; Female; Humans; I

1973
Infant cot deaths.
    British medical journal, 1971, Jul-10, Volume: 3, Issue:5766

    Topics: Airway Obstruction; Cough; Death, Sudden; Humans; Infant, Newborn; Mucus; Respiratory Tract Infectio

1971
Intraluminal exudates of nonrespiratory bronchioles in pulmonary emphysema.
    Human pathology, 1971, Volume: 2, Issue:2

    Topics: Airway Obstruction; Bronchi; Exudates and Transudates; Histiocytes; Humans; Leukocytes; Male; Middle

1971
[Case of tracheal obstruction by a mucous concretion. Tracheotomy--recovery].
    Rassegna internazionale di clinica e terapia, 1971, Nov-30, Volume: 51, Issue:22

    Topics: Airway Obstruction; Female; Humans; Intubation, Intratracheal; Middle Aged; Mucus; Postoperative Com

1971
Bronchial atresia: a rare cause of unilateral lung hypertranslucency.
    Journal of the Canadian Association of Radiologists, 1971, Volume: 22, Issue:1

    Topics: Adult; Airway Obstruction; Angiography; Bronchi; Bronchial Diseases; Bronchial Neoplasms; Bronchogra

1971