guaifenesin has been researched along with Aging in 51 studies
Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "History of respiratory infections were not associated with an increased prevalence of EFL." | 2.78 | [Chronic cough in the elderly is associated with expiratory flow limitation]. ( Barthélémy, JC; Costes, F; Frappé, E; Gautier-Guillot, M; Maudoux, D; Roche, F, 2013) |
| " Thus, NEC-stressed (N-S) rat pups were orally dosed with breastmilk components lysozyme (N-S-LYS) or docosahexaenoic acid (N-S-DHA)." | 1.56 | Impact of Developmental Age, Necrotizing Enterocolitis Associated Stress, and Oral Therapeutic Intervention on Mucus Barrier Properties. ( Carlson, TL; Carrier, RL; Claud, EC; Lock, JY; Lu, J; Yu, Y, 2020) |
| "A variety of neurological and psychiatric disorders have recently been linked to coeliac disease and gluten sensitivity." | 1.39 | Gliadin antibodies in older population and neurological and psychiatric disorders. ( Collin, P; Haimila, K; Kaukinen, K; Krekelä, I; Laurila, K; Luostarinen, L; Mäki, M; Nyrke, T; Partanen, J; Patrikainen, H; Ruuskanen, A; Tillonen, J; Valve, R, 2013) |
| "It is stated that chronic obstructive pulmonary diseases patients observe the significant variation of bronchial clearance's tempos, imbalance in the system of lipids' peroxide oxidation and antioxidant defense during aggravation and remission." | 1.35 | [State of the mucociliary system in patients of senior age with chronic obstructive pulmonary diseases]. ( Kozlov, BI; Nagin, AP; Vishniakov, AA, 2008) |
| "To evaluate lung inflammation, mucus metaplasia and AHR in relationship with age in murine models of allergic asthma comparing young and older mice." | 1.34 | Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. ( Busse, PJ; Li, XM; Schofield, B; Srivastava, K; Zhang, TF, 2007) |
| "Eosinophilia was associated with asthma and with phlegm production." | 1.28 | Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study. ( O'Connor, GT; Sparrow, D; Tollerud, DJ; Weiss, ST, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (19.61) | 18.7374 |
| 1990's | 12 (23.53) | 18.2507 |
| 2000's | 11 (21.57) | 29.6817 |
| 2010's | 13 (25.49) | 24.3611 |
| 2020's | 5 (9.80) | 2.80 |
| Authors | Studies |
|---|---|
| Check, JH | 1 |
| Saleem, W | 1 |
| Ren, X | 1 |
| Van Den Broeck, W | 1 |
| Nauwynck, H | 1 |
| Park, YJ | 1 |
| Lee, JM | 1 |
| Choi, KH | 1 |
| Brown, R | 1 |
| Paulsen, M | 1 |
| Schmidt, S | 1 |
| Schatterny, J | 1 |
| Frank, A | 1 |
| Hirtz, S | 1 |
| Delaney, R | 1 |
| Doherty, D | 1 |
| Hagner, M | 1 |
| Taggart, C | 1 |
| Weldon, S | 1 |
| Mall, MA | 1 |
| Lock, JY | 1 |
| Carlson, TL | 1 |
| Yu, Y | 1 |
| Lu, J | 1 |
| Claud, EC | 1 |
| Carrier, RL | 1 |
| Powell, DN | 1 |
| Swimm, A | 1 |
| Sonowal, R | 1 |
| Bretin, A | 1 |
| Gewirtz, AT | 1 |
| Jones, RM | 1 |
| Kalman, D | 1 |
| Elderman, M | 1 |
| Sovran, B | 1 |
| Hugenholtz, F | 1 |
| Graversen, K | 1 |
| Huijskes, M | 1 |
| Houtsma, E | 1 |
| Belzer, C | 1 |
| Boekschoten, M | 1 |
| de Vos, P | 1 |
| Dekker, J | 1 |
| Wells, J | 1 |
| Faas, M | 1 |
| Esser, D | 1 |
| Lange, J | 1 |
| Marinos, G | 1 |
| Sieber, M | 1 |
| Best, L | 1 |
| Prasse, D | 1 |
| Bathia, J | 1 |
| Rühlemann, MC | 1 |
| Boersch, K | 1 |
| Jaspers, C | 1 |
| Sommer, F | 1 |
| Frappé, E | 1 |
| Gautier-Guillot, M | 1 |
| Barthélémy, JC | 1 |
| Maudoux, D | 1 |
| Roche, F | 1 |
| Costes, F | 1 |
| Sun, X | 1 |
| Olivier, AK | 1 |
| Yi, Y | 1 |
| Pope, CE | 1 |
| Hayden, HS | 1 |
| Liang, B | 1 |
| Sui, H | 1 |
| Zhou, W | 1 |
| Hager, KR | 1 |
| Zhang, Y | 1 |
| Liu, X | 1 |
| Yan, Z | 1 |
| Fisher, JT | 1 |
| Keiser, NW | 1 |
| Song, Y | 1 |
| Tyler, SR | 1 |
| Goeken, JA | 1 |
| Kinyon, JM | 1 |
| Radey, MC | 1 |
| Fligg, D | 1 |
| Wang, X | 1 |
| Xie, W | 1 |
| Lynch, TJ | 1 |
| Kaminsky, PM | 1 |
| Brittnacher, MJ | 1 |
| Miller, SI | 1 |
| Parekh, K | 1 |
| Meyerholz, DK | 1 |
| Hoffman, LR | 1 |
| Frana, T | 1 |
| Stewart, ZA | 1 |
| Engelhardt, JF | 1 |
| Macierzanka, A | 1 |
| Mackie, AR | 1 |
| Bajka, BH | 1 |
| Rigby, NM | 1 |
| Nau, F | 1 |
| Dupont, D | 1 |
| Merchant, HA | 1 |
| Rabbie, SC | 1 |
| Varum, FJ | 1 |
| Afonso-Pereira, F | 1 |
| Basit, AW | 1 |
| Millerick-May, ML | 1 |
| Karmaus, W | 1 |
| Derksen, FJ | 1 |
| Berthold, B | 1 |
| Robinson, NE | 1 |
| Allinson, JP | 1 |
| Hardy, R | 1 |
| Donaldson, GC | 1 |
| Shaheen, SO | 1 |
| Kuh, D | 1 |
| Wedzicha, JA | 1 |
| Lange, P | 1 |
| Vestbo, J | 1 |
| Nagin, AP | 1 |
| Kozlov, BI | 1 |
| Vishniakov, AA | 1 |
| Chiou, MT | 1 |
| Yang, CY | 1 |
| Chang, TC | 1 |
| Chen, C | 1 |
| Lin, CF | 1 |
| Ye, LJ | 1 |
| Cardwell, JM | 1 |
| Wood, JL | 1 |
| Smith, KC | 1 |
| Newton, JR | 1 |
| Hasegawa, A | 1 |
| Otsuki, S | 1 |
| Pauli, C | 1 |
| Miyaki, S | 1 |
| Patil, S | 1 |
| Steklov, N | 1 |
| Kinoshita, M | 1 |
| Koziol, J | 1 |
| D'Lima, DD | 1 |
| Lotz, MK | 1 |
| Ruuskanen, A | 1 |
| Kaukinen, K | 1 |
| Collin, P | 1 |
| Krekelä, I | 1 |
| Patrikainen, H | 1 |
| Tillonen, J | 1 |
| Nyrke, T | 1 |
| Laurila, K | 1 |
| Haimila, K | 1 |
| Partanen, J | 1 |
| Valve, R | 1 |
| Mäki, M | 1 |
| Luostarinen, L | 1 |
| Wild, C | 1 |
| Huettel, M | 1 |
| Klueter, A | 1 |
| Kremb, SG | 1 |
| Rasheed, MY | 1 |
| Jørgensen, BB | 1 |
| Newton, JL | 2 |
| Millery, J | 1 |
| Briand, L | 1 |
| Bézirard, V | 1 |
| Blon, F | 1 |
| Fenech, C | 1 |
| Richard-Parpaillon, L | 1 |
| Quennedey, B | 1 |
| Pernollet, JC | 1 |
| Gascuel, J | 1 |
| Tomita, H | 1 |
| Nakashima, T | 1 |
| Maeda, A | 1 |
| Umeno, H | 1 |
| Sato, K | 2 |
| Busse, PJ | 1 |
| Zhang, TF | 1 |
| Srivastava, K | 1 |
| Schofield, B | 1 |
| Li, XM | 1 |
| Haas, CF | 1 |
| Loik, PS | 1 |
| Gay, SE | 1 |
| Fernandes, JL | 1 |
| Viana, SL | 1 |
| Mendonça, JL | 1 |
| Freitas, FM | 1 |
| Bezerra, AS | 1 |
| Lima, GA | 1 |
| Matos, VL | 1 |
| Cunha, NF | 1 |
| Martins, RR | 1 |
| Freitas, RM | 1 |
| Tos, M | 1 |
| Shub, MD | 1 |
| Pang, KY | 1 |
| Swann, DA | 1 |
| Walker, WA | 1 |
| Parlanti, IA | 1 |
| Monis, B | 1 |
| van den Dobbelsteen, GP | 1 |
| van Rees, EP | 1 |
| Tabata, M | 1 |
| Tomomasa, T | 1 |
| Itoh, K | 1 |
| Morikawa, A | 1 |
| Zilberg, D | 1 |
| Klesius, PH | 1 |
| Okuyama, H | 1 |
| Urao, M | 1 |
| Lee, D | 1 |
| Abe, A | 1 |
| Drongowski, RA | 1 |
| Harmon, CM | 1 |
| Coran, AG | 1 |
| Hirano, M | 1 |
| Ouwehand, AC | 1 |
| Isolauri, E | 1 |
| Kirjavainen, PV | 1 |
| Salminen, SJ | 1 |
| Nakano, S | 1 |
| Werner, E | 1 |
| Meyer, P | 1 |
| Hentschel, H | 1 |
| Willemsen, PT | 1 |
| de Graaf, FK | 1 |
| Choi, SH | 1 |
| Kornegay, ET | 1 |
| Eigel, WN | 1 |
| Foulkes, EC | 1 |
| Mort, TL | 1 |
| Buncher, CR | 1 |
| Tollerud, DJ | 1 |
| O'Connor, GT | 1 |
| Sparrow, D | 1 |
| Weiss, ST | 1 |
| Conway, PL | 1 |
| Welin, A | 1 |
| Cohen, PS | 1 |
| Steuhl, KP | 1 |
| Knorr, M | 1 |
| Phillips, TE | 1 |
| Phillips, TL | 1 |
| Neutra, MR | 1 |
| Sørensen, CH | 1 |
| Larsen, PL | 1 |
| Mills, AN | 1 |
| Lopez-Vidriero, MT | 1 |
| Haworth, SG | 1 |
| Kessing, SV | 1 |
| De Jorge, FB | 1 |
| Petersen, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005284] | 0 participants | Observational | 1985-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for guaifenesin and Aging
| Article | Year |
|---|---|
Functions of the Microbiota for the Physiology of Animal Metaorganisms.
Topics: Aging; Animals; Computational Biology; Health Status; Host Microbial Interactions; Humans; Microbiot | 2019 |
Changes in upper gastrointestinal physiology with age.
Topics: Aging; Bicarbonates; Humans; Mucus; Upper Gastrointestinal Tract | 2004 |
Effect of age-related changes in gastric physiology on tolerability of medications for older people.
Topics: Aged; Aging; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Motility; Helicobacte | 2005 |
Airway clearance applications in the elderly and in patients with neurologic or neuromuscular compromise.
Topics: Aged; Aging; Airway Obstruction; Humans; Lung; Mucus; Nervous System Diseases; Neuromuscular Disease | 2007 |
Mucoid degeneration of the anterior cruciate ligament: magnetic resonance imaging findings of an underdiagnosed entity.
Topics: Aging; Anterior Cruciate Ligament; Diagnosis, Differential; Ganglion Cysts; Humans; Joint Diseases; | 2008 |
Mucosal immune responses to pneumococcal polysaccharides: implications for vaccination.
Topics: Aging; Bacterial Vaccines; Humans; Mucus; Polysaccharides, Bacterial; Splenectomy; Streptococcal Inf | 1995 |
[Dryness of nasal mucosa in the aged and the treatment].
Topics: Aged; Aging; Humans; Humidity; Mucus; Nasal Mucosa; Nebulizers and Vaporizers; Nose Diseases | 2001 |
1 trial available for guaifenesin and Aging
| Article | Year |
|---|---|
[Chronic cough in the elderly is associated with expiratory flow limitation].
Topics: Aged; Aging; Bronchitis; Chronic Disease; Cough; Exhalation; Humans; Mucus; Prevalence; Pulmonary Di | 2013 |
43 other studies available for guaifenesin and Aging
| Article | Year |
|---|---|
Successful pregnancy despite advanced age and elevated serum follicle stimulating hormone levels--a case report.
Topics: Aging; Calcium Channel Blockers; Clomiphene; Estradiol; Ethinyl Estradiol; Female; Follicle Stimulat | 2000 |
Changes in intestinal morphology, number of mucus-producing cells and expression of coronavirus receptors APN, DPP4, ACE2 and TMPRSS2 in pigs with aging.
Topics: Aging; Angiotensin-Converting Enzyme 2; Animals; Dipeptidyl Peptidase 4; Ileum; Intestinal Mucosa; J | 2023 |
Harmonic components of photoplethysmography and pathological patterns: A cross-sectional study.
Topics: Adult; Aging; Cross-Sectional Studies; Female; Humans; Middle Aged; Mucus; Photoplethysmography; Ret | 2023 |
Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.
Topics: Aging; Animals; Antibodies; Apoptosis; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Cytokine | 2020 |
Impact of Developmental Age, Necrotizing Enterocolitis Associated Stress, and Oral Therapeutic Intervention on Mucus Barrier Properties.
Topics: Administration, Oral; Aging; Animals; DNA; Docosahexaenoic Acids; Enterobacter cloacae; Enterocoliti | 2020 |
Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging.
Topics: Aging; Animals; Bacteria; Cell Differentiation; Epithelial Cells; Female; Goblet Cells; Indoles; Int | 2020 |
The effect of age on the intestinal mucus thickness, microbiota composition and immunity in relation to sex in mice.
Topics: Age Factors; Aging; Animals; Biodiversity; Cell Differentiation; Colon; Dendritic Cells; Female; Gas | 2017 |
Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets.
Topics: Aging; Animals; Atrophy; Bacteria; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regula | 2014 |
Transport of particles in intestinal mucus under simulated infant and adult physiological conditions: impact of mucus structure and extracellular DNA.
Topics: Aging; Animals; Biological Transport; Diffusion; DNA; Extracellular Space; Intestinal Mucosa; Intest | 2014 |
Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery.
Topics: Aging; Animals; Gastric Juice; Gastrointestinal Tract; Hydrogen-Ion Concentration; Intestinal Secret | 2014 |
Airborne particulates (PM10) and tracheal mucus: A case-control study at an American Thoroughbred racetrack.
Topics: Aging; Air Pollution, Indoor; Animals; Case-Control Studies; Horses; Housing, Animal; Mucus; Particl | 2015 |
The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development.
Topics: Adult; Age Factors; Aging; Chronic Disease; Disease Progression; Female; Humans; Lung; Male; Middle | 2016 |
Chronic Mucus Hypersecretion and the Natural History of Chronic Obstructive Pulmonary Disease.
Topics: Aging; Female; Humans; Lung; Male; Mucus; Pulmonary Disease, Chronic Obstructive; Smoking | 2016 |
[State of the mucociliary system in patients of senior age with chronic obstructive pulmonary diseases].
Topics: Aged; Aging; Antioxidants; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Mucociliary Cleara | 2008 |
Shedding pattern and serological profile of porcine circovirus type 2 infection in cesarean-derived, colostrum-deprived and farm-raised pigs.
Topics: Aging; Animals; Cesarean Section; Circoviridae Infections; Circovirus; Colostrum; Feces; Mucus; Orop | 2011 |
Descriptive results from a longitudinal study of airway inflammation in British National Hunt racehorses.
Topics: Aging; Animals; Horse Diseases; Horses; Inflammation; Longitudinal Studies; Mucus; Neutrophils; Odds | 2011 |
Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anterior Cruciate Ligament; Cartilage; Female; Humans; Inflam | 2012 |
Gliadin antibodies in older population and neurological and psychiatric disorders.
Topics: Aged; Aged, 80 and over; Aging; Antibodies; Endoscopy, Gastrointestinal; Enzyme-Linked Immunosorbent | 2013 |
Coral mucus functions as an energy carrier and particle trap in the reef ecosystem.
Topics: Aging; Animals; Anthozoa; Australia; Carbon; Ecosystem; Energy Metabolism; Eukaryota; Food Chain; Ge | 2004 |
Specific expression of olfactory binding protein in the aerial olfactory cavity of adult and developing Xenopus.
Topics: Aging; Amino Acid Sequence; Animals; Antibody Specificity; Base Sequence; Brain Chemistry; Cloning, | 2005 |
Age related changes in the distribution of laryngeal glands in the human adult larynx.
Topics: Adult; Aged; Aged, 80 and over; Aging; Exocrine Glands; Female; Humans; Image Processing, Computer-A | 2006 |
Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice.
Topics: Aging; Animals; Asthma; B-Lymphocytes; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Enzy | 2007 |
Distribution of mucus producing elements in the respiratory tract. Differences between upper and lower airway.
Topics: Adult; Aging; Bronchi; Child; Child, Preschool; Exocrine Glands; Female; Fetus; Humans; Infant; Infa | 1983 |
Age-related changes in chemical composition and physical properties of mucus glycoproteins from rat small intestine.
Topics: Aging; Amino Acids; Animals; Carbohydrates; Centrifugation, Density Gradient; Chromatography, Gel; E | 1983 |
Microscopic study of the mucification of vaginal epithelium in immature and prepuberal rats. Changes with age, castration and hormone replacement, and data on the ultrastructure of the luminal glycocalyx.
Topics: Aging; Animals; Castration; Chorionic Gonadotropin; Estrogens; Female; Gonadotropins, Equine; Mucus; | 1980 |
Effect of 10% ethanol and sofalcone on prostaglandin E2 content, mucus gel thickness, and experimental ulcers in the stomach of developing rats.
Topics: Aging; Animals; Animals, Newborn; Anti-Ulcer Agents; Chalcone; Chalcones; Dinoprostone; Dose-Respons | 1996 |
Quantification of immunoglobulin in the serum and mucus of channel catfish at different ages and following infection with Edwardsiella ictaluri.
Topics: Aging; Animals; Antibodies, Bacterial; Bacteremia; Enzyme-Linked Immunosorbent Assay; Fish Diseases; | 1997 |
Changes, with age, in the phospholipid content of the intestinal mucus layer of the newborn rabbit.
Topics: Aging; Animals; Animals, Newborn; Female; Intestinal Absorption; Intestinal Mucosa; Male; Mucus; Pho | 1998 |
Age-related changes in the human laryngeal glands.
Topics: Adult; Aged; Aged, 80 and over; Aging; Exocrine Glands; Female; Humans; Larynx; Male; Mucus | 1998 |
Adhesion of four Bifidobacterium strains to human intestinal mucus from subjects in different age groups.
Topics: Adult; Aged; Aged, 80 and over; Aging; Bacterial Adhesion; Bifidobacterium; Feces; Humans; Infant; I | 1999 |
[Evidence and estimation of immunoglobulins in human nasal mucosa and nasal fluid--a study towards age dependence (author's transl)].
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Fluorescent Antibody Technique; Humans; Immunoglo | 1978 |
The kidney of a teleost, Spinachia spinachia. II. Histochemical identification of sialic acid-containing glycoprotein and fine structure of mucus secreting cells.
Topics: Aging; Animals; Fishes; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Mucus; Sialoglyco | 1979 |
Age and serotype dependent binding of K88 fimbriae to porcine intestinal receptors.
Topics: Aging; Animals; Bacterial Adhesion; Binding Sites; Escherichia coli; Fimbriae, Bacterial; Glycoside | 1992 |
Characterization of small intestinal mucus glycoproteins from pigs of various ages.
Topics: Aging; Animals; Carbohydrates; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Glycoprotei | 1991 |
Intestinal cadmium permeability in mature and immature rats.
Topics: Aging; Animals; Cadmium; Cycloleucine; Ethanol; Jejunum; Male; Mucus; Permeability; Rats; Rats, Inbr | 1991 |
Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels. The Normative Aging Study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Asthma; Eosinophilia; Humans; Hypersensitivity; Immunoglobuli | 1991 |
Presence of K88-specific receptors in porcine ileal mucus is age dependent.
Topics: Aging; Animals; Antibodies, Monoclonal; Bacterial Adhesion; Centrifugation; Epithelium; Escherichia | 1990 |
[The second, mucus-secreting system of the conjunctiva. Ultrastructural findings].
Topics: Adolescent; Adult; Aged; Aging; Cell Count; Child; Child, Preschool; Conjunctiva; Cytoplasmic Granul | 1990 |
Cholinergic responsiveness of goblet cells during intestinal maturation.
Topics: Aging; Animals; Animals, Newborn; Carbachol; Female; Ileum; Intestinal Mucosa; Mucus; Organ Culture | 1989 |
IgD in nasopharyngeal secretions and tonsils from otitis-prone children.
Topics: Acute Disease; Adenoids; Adolescent; Aging; Child; Child, Preschool; Female; Fetal Blood; Humans; Im | 1988 |
Development of the airway epithelium and submucosal glands in the pig lung: changes in epithelial glycoprotein profiles.
Topics: Aging; Animals; Animals, Newborn; Bronchi; Cell Count; Epithelium; Exocrine Glands; Glycoproteins; L | 1986 |
Mucous gland system of the conjunctiva. A quantitative normal anatomical study.
Topics: Adolescent; Adult; Aged; Aging; Biopsy; Child; Child, Preschool; Conjunctiva; Female; Humans; Infant | 1968 |
Sex differences and maturation influence on the chemical composition in Chaetopterus variopedatus Rénier 1804 (Polychaeta).
Topics: Aging; Animals; Annelida; Body Composition; Calcium; Chlorides; Copper; Feces; Female; Glycogen; Iod | 1968 |