Page last updated: 2024-10-28

guaifenesin and 2019 Novel Coronavirus Disease

guaifenesin has been researched along with 2019 Novel Coronavirus Disease in 27 studies

Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Research Excerpts

ExcerptRelevanceReference
"Allergic asthma is a chronic respiratory disease caused by an inappropriate immune response."5.72Gekko gecko extract attenuates airway inflammation and mucus hypersecretion in a murine model of ovalbumin-induced asthma. ( Kim, JS; Lee, JH; Lee, S; Moon, BC; Nam, HH; Noh, P; Ryu, SM; Seo, YS; Yang, S, 2022)
"Allergic asthma is a chronic respiratory disease caused by an inappropriate immune response."1.72Gekko gecko extract attenuates airway inflammation and mucus hypersecretion in a murine model of ovalbumin-induced asthma. ( Kim, JS; Lee, JH; Lee, S; Moon, BC; Nam, HH; Noh, P; Ryu, SM; Seo, YS; Yang, S, 2022)
"The pandemic of the coronavirus disease 2019 (COVID-19) has brought a global public health crisis."1.62The proteomic characteristics of airway mucus from critical ill COVID-19 patients. ( Gu, G; Li, Y; Liu, F; Liu, X; Lu, W; Luo, J; Wang, T; Xu, J; Zhang, Z; Zhao, J; Zhong, N; Zhu, A, 2021)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's27 (100.00)2.80

Authors

AuthorsStudies
Nam, HH1
Lee, JH1
Ryu, SM1
Lee, S1
Yang, S1
Noh, P1
Moon, BC1
Kim, JS1
Seo, YS1
Kumar, SS1
Binu, A1
Devan, AR1
Nath, LR1
Li, D1
Luan, N1
Li, J1
Zhao, H1
Zhang, Y2
Long, R1
Jiang, G1
Fan, S1
Xu, X1
Cao, H1
Wang, Y1
Liao, Y1
Wang, L1
Liu, L1
Liu, C1
Li, Q1
Meyerholz, DK1
Reznikov, LR1
Haroun, RA1
Osman, WH1
Eessa, AM1
Ousingsawat, J1
Centeio, R1
Cabrita, I1
Talbi, K1
Zimmer, O1
Graf, M1
Göpferich, A1
Schreiber, R1
Kunzelmann, K1
Aggarwal, V1
Sunder, S1
Verma, SR1
Pednekar, DD1
Liguori, MA1
Marques, CNH1
Zhang, T1
Zhang, N1
Zhou, Z1
Amoako, K1
Gu, H1
Dickey, BF1
Chen, J1
Peebles, RS1
Su, P1
Zhou, F1
Zhang, L2
Kodchakorn, K1
Chokepaichitkool, T1
Kongtawelert, P1
Li, H1
Kuga, K1
Ito, K1
Esam, Z2
Matson, MJ1
Yinda, CK1
Seifert, SN1
Bushmaker, T1
Fischer, RJ1
van Doremalen, N1
Lloyd-Smith, JO1
Munster, VJ1
Khashkhosha, HK1
Elhadi, M1
Pujadas, E1
Chaudhry, F1
McBride, R1
Richter, F1
Zhao, S1
Wajnberg, A1
Nadkarni, G1
Glicksberg, BS1
Houldsworth, J1
Cordon-Cardo, C1
Lu, W2
Liu, X2
Wang, T2
Liu, F2
Zhu, A2
Lin, Y1
Luo, J2
Ye, F1
He, J1
Zhao, J2
Li, Y3
Zhong, N2
Poon, WCK1
Brown, AT1
Direito, SOL1
Hodgson, DJM1
Le Nagard, L1
Lips, A1
MacPhee, CE1
Marenduzzo, D1
Royer, JR1
Silva, AF1
Thijssen, JHJ1
Titmuss, S1
Liu, Y1
Lv, J1
Liu, J1
Li, M1
Xie, J1
Lv, Q1
Deng, W1
Zhou, N1
Zhou, Y1
Song, J1
Wang, P1
Qin, C1
Tong, WM1
Huang, B1
Zhang, Z1
Gu, G1
Xu, J1
Edwards, DA1
Ausiello, D1
Salzman, J1
Devlin, T1
Langer, R1
Beddingfield, BJ1
Fears, AC1
Doyle-Meyers, LA1
Redmann, RK1
Killeen, SZ1
Maness, NJ1
Roy, CJ1
Zhang, H1
Zhou, J1
Chen, R1
Ren, Y1
Cai, J1
Zhao, L1
Fei, X1
Liu, Z1
Yuan, L1
Wang, C1
Guo, L1
Wang, M1
Mao, N1
An, C1
Xu, L1
Long, E1
Sloan, A1
Cutts, T1
Griffin, BD1
Kasloff, S1
Schiffman, Z1
Chan, M1
Audet, J1
Leung, A1
Kobasa, D1
Stein, DR1
Safronetz, D1
Poliquin, G1
Posch, W1
Lass-Flörl, C1
Wilflingseder, D1
Wittig, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Nasopharyngeal Wash With Normal Saline on SARS-CoV2 Viral Load: A Randomized Controlled Trial[NCT05525832]50 participants (Actual)Interventional2021-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for guaifenesin and 2019 Novel Coronavirus Disease

ArticleYear
Influence of SARS-CoV-2 on airway mucus production: A review and proposed model.
    Veterinary pathology, 2022, Volume: 59, Issue:4

    Topics: Animals; COVID-19; Ferrets; Mucus; Pandemics; SARS-CoV-2

2022
Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome.
    Folia microbiologica, 2022, Volume: 67, Issue:6

    Topics: COVID-19; Diabetes Mellitus, Type 2; Dysbiosis; Gastrointestinal Microbiome; Humans; Mucins; Mucus;

2022
From Static to Dynamic: A Review on the Role of Mucus Heterogeneity in Particle and Microbial Transport.
    ACS biomaterials science & engineering, 2022, 07-11, Volume: 8, Issue:7

    Topics: COVID-19; Drug Delivery Systems; Humans; Mucus; SARS-CoV-2

2022
A hypothesis on the role of the human immune system in covid-19.
    Medical hypotheses, 2020, Volume: 143

    Topics: Ageusia; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-1

2020
Transmission risk of viruses in large mucosalivary droplets on the surface of objects: A time-based analysis.
    Infectious diseases now, 2021, Volume: 51, Issue:3

    Topics: Air Microbiology; Bacteria; Cough; COVID-19; Desiccation; Disease Transmission, Infectious; Equipmen

2021
[Mucociliary clearance in COVID-19 - an underestimated danger area in early phase of disease?]
    MMW Fortschritte der Medizin, 2021, Volume: 163, Issue:Suppl 5

    Topics: Animals; Cough; COVID-19; Humans; Mucociliary Clearance; Mucus; SARS-CoV-2

2021

Other Studies

21 other studies available for guaifenesin and 2019 Novel Coronavirus Disease

ArticleYear
Gekko gecko extract attenuates airway inflammation and mucus hypersecretion in a murine model of ovalbumin-induced asthma.
    Journal of ethnopharmacology, 2022, Jan-10, Volume: 282

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; COVID-19; Cytokines; Female; F

2022
Mucus targeting as a plausible approach to improve lung function in COVID-19 patients.
    Medical hypotheses, 2021, Volume: 156

    Topics: Asthma; COVID-19; Humans; Lung; Mucus; SARS-CoV-2

2021
Waning antibodies from inactivated SARS-CoV-2 vaccination offer protection against infection without antibody-enhanced immunopathology in rhesus macaque pneumonia models.
    Emerging microbes & infections, 2021, Volume: 10, Issue:1

    Topics: Alveolar Epithelial Cells; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antibody-Dependent

2021
Evaluation of serum total sialic acid in moderate COVID-19 patients with and without gastrointestinal tract manifestations.
    Tissue & cell, 2022, Volume: 74

    Topics: Adult; Biomarkers; COVID-19; Enzyme-Linked Immunosorbent Assay; Female; Gastrointestinal Tract; Huma

2022
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
    International journal of molecular sciences, 2022, Jan-19, Volume: 23, Issue:3

    Topics: Animals; Asthma; Cells, Cultured; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Ca

2022
Airway Mucus Dysfunction in COVID-19.
    American journal of respiratory and critical care medicine, 2022, 12-01, Volume: 206, Issue:11

    Topics: COVID-19; Humans; Mucus; Prevalence; Respiratory System

2022
Motile cilia and microvillar: accomplices of SARS-CoV-2 in penetrating mucus barrier and infecting airway epithelium.
    Signal transduction and targeted therapy, 2023, 03-14, Volume: 8, Issue:1

    Topics: Cilia; COVID-19; Epithelium; Humans; Mucus; SARS-CoV-2

2023
Purification and characterisation of heparin-like sulfated polysaccharides with potent anti-SARS-CoV-2 activity from snail mucus of Achatina fulica.
    Carbohydrate research, 2023, Volume: 529

    Topics: Animals; COVID-19; Glycosaminoglycans; Heparin; Humans; Mucus; Polysaccharides; SARS-CoV-2; Snails;

2023
Visual prediction and parameter optimization of viral dynamics in the mucus milieu of the upper airway based on CFPD-HCD analysis.
    Computer methods and programs in biomedicine, 2023, Volume: 238

    Topics: COVID-19; Humans; Mucus; Nasal Cavity; Nasopharynx; SARS-CoV-2

2023
Protective potential of expectorants against COVID-19.
    Medical hypotheses, 2020, Volume: 142

    Topics: Air Microbiology; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug T

2020
Effect of Environmental Conditions on SARS-CoV-2 Stability in Human Nasal Mucus and Sputum.
    Emerging infectious diseases, 2020, Volume: 26, Issue:9

    Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Hot Temperature; Humans; Humidity; Mucus; Nasal C

2020
SARS-CoV-2 viral load predicts COVID-19 mortality.
    The Lancet. Respiratory medicine, 2020, Volume: 8, Issue:9

    Topics: Aged; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Humans; Male; Middle Aged; Mucus; N

2020
Elevated MUC1 and MUC5AC mucin protein levels in airway mucus of critical ill COVID-19 patients.
    Journal of medical virology, 2021, Volume: 93, Issue:2

    Topics: Cohort Studies; COVID-19; Critical Illness; Female; Humans; Male; Middle Aged; Mucin 5AC; Mucin-1; M

2021
Soft matter science and the COVID-19 pandemic.
    Soft matter, 2020, Sep-23, Volume: 16, Issue:36

    Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Disinfection; Humans; Mucus; Nanoparticles; Pande

2020
Protective potential of expectorants against COVID-19.
    Medical hypotheses, 2020, Volume: 142

    Topics: Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Dioxolanes

2020
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19.
    Cell research, 2020, Volume: 30, Issue:12

    Topics: Animals; Cell Line; COVID-19; Epithelial Cells; Humans; Hypoxia; Interferon-beta; Interferon-gamma;

2020
The proteomic characteristics of airway mucus from critical ill COVID-19 patients.
    Life sciences, 2021, Mar-15, Volume: 269

    Topics: Aged; Amino Acids; Bronchoscopy; Case-Control Studies; Cholesterol; COVID-19; Critical Illness; Fema

2021
Exhaled aerosol increases with COVID-19 infection, age, and obesity.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 02-23, Volume: 118, Issue:8

    Topics: Aerosols; Age Factors; Animals; Body Mass Index; Cohort Studies; COVID-19; Exhalation; Humans; Mucus

2021
Autopsy and Histologic Findings of Patients with New Coronavirus Pneumonia: The Pathologic Associations with Hypoxemia.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Feb-13, Volume: 27

    Topics: Aged; Aged, 80 and over; Alveolar Epithelial Cells; Autopsy; Cell Aggregation; COVID-19; Female; Hum

2021
Simulated sunlight decreases the viability of SARS-CoV-2 in mucus.
    PloS one, 2021, Volume: 16, Issue:6

    Topics: COVID-19; Decontamination; Humans; Microbial Viability; Mucus; SARS-CoV-2; Sunlight; Virus Inactivat

2021
SARS-CoV-2-infected primary human airway epithelia illustrate mucus hypersecretion.
    The Journal of allergy and clinical immunology, 2021, Volume: 148, Issue:3

    Topics: COVID-19; Humans; Mucus; Respiratory System; SARS-CoV-2

2021