Page last updated: 2024-10-17

guaiacol and Reperfusion Injury

guaiacol has been researched along with Reperfusion Injury in 6 studies

Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"We used cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 (TXA2) receptor, and superoxide dismutase (SOD) with catalase to examine their protective effect against reperfusion injury in rat skeletal muscle."7.69Reduction of reperfusion injury in rat skeletal muscle following administration of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor. ( Chang, H; Cheng, HT, 1995)
"We used cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 (TXA2) receptor, and superoxide dismutase (SOD) with catalase to examine their protective effect against reperfusion injury in rat skeletal muscle."3.69Reduction of reperfusion injury in rat skeletal muscle following administration of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor. ( Chang, H; Cheng, HT, 1995)
"Zingerone is a component of ginger with multiple pharmacological activities."1.72The protective role of exogenous Ghrelin versus its combination with Zingerone on experimentally induced gastric ischemic-reperfusion in adult male albino rats. ( Samy, W, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Samy, W1
Gaire, BP1
Kwon, OW1
Park, SH1
Chun, KH1
Kim, SY1
Shin, DY1
Choi, JW1
Lee, EJ2
Chen, HY2
Hung, YC1
Chen, TY2
Lee, MY2
Yu, SC1
Chen, YH1
Chuang, IC1
Wu, TS2
Arce, C1
Diaz-Castroverde, S1
Canales, MJ1
Marco-Contelles, J1
Samadi, A1
Oset-Gasque, MJ1
González, MP1
Hsu, YS1
Hu, YL1
Chang, GL1
Cheng, HT1
Chang, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Production of Fortified Biscuit With Chickpea and Crushed Peanut and Evaluating Its Effectiveness in Terms of Its Acceptability and Cognitive Performance: a Pilot Study Among Egyptian Primary School-aged Children[NCT05281146]80 participants (Actual)Interventional2018-11-26Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for guaiacol and Reperfusion Injury

ArticleYear
The protective role of exogenous Ghrelin versus its combination with Zingerone on experimentally induced gastric ischemic-reperfusion in adult male albino rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, May-31, Volume: 68, Issue:5

    Topics: Animals; Gastric Mucosa; Ghrelin; Guaiacol; Ischemia; Male; Rats; Rats, Wistar; Reperfusion Injury;

2022
Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Line; Cell Proliferation; Cell Survival; Guaiacol; I

2015
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Lin

2009
Drugs for stroke: action of nitrone (Z)-N-(2-bromo-5-hydroxy-4-methoxybenzylidene)-2-methylpropan-2-amine oxide on rat cortical neurons in culture subjected to oxygen-glucose-deprivation.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Animals; Benzylidene Compounds; Brain; Caspase 3; Cell Survival; Cells, Cultured; Female; Glucose; G

2012
Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice.
    Free radical biology & medicine, 2005, Aug-15, Volume: 39, Issue:4

    Topics: Animals; Antioxidants; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Free Radical Sc

2005
Reduction of reperfusion injury in rat skeletal muscle following administration of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
    The Thoracic and cardiovascular surgeon, 1995, Volume: 43, Issue:2

    Topics: Animals; Catalase; Female; Guaiacol; Hindlimb; Ischemia; Lignans; Muscle, Skeletal; Random Allocatio

1995