guaiacol has been researched along with Parkinson Disease in 3 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marchiani, A | 1 |
| Mammi, S | 1 |
| Siligardi, G | 1 |
| Hussain, R | 1 |
| Tessari, I | 1 |
| Bubacco, L | 1 |
| Delogu, G | 1 |
| Fabbri, D | 1 |
| Dettori, MA | 1 |
| Sanna, D | 1 |
| Dedola, S | 1 |
| Serra, PA | 1 |
| Ruzza, P | 1 |
| Choi, JS | 1 |
| Bae, WY | 1 |
| Park, C | 1 |
| Jeong, JW | 1 |
| Kabuto, H | 1 |
| Yamanushi, TT | 1 |
3 other studies available for guaiacol and Parkinson Disease
| Article | Year |
|---|---|
Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties.
Topics: Adrenal Gland Neoplasms; alpha-Synuclein; Alzheimer Disease; Animals; Antioxidants; Cell Line, Tumor | 2013 |
Zingerone activates VMAT2 during MPP(+) -induced Cell Death.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Death; Corpus Striatum; Disease Models, | 2015 |
Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Corpus Striatum; Disease Models, Animal; Dopamine; E | 2011 |