guaiacol has been researched along with Muscle Contraction in 10 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zingerone, a pungent component of ginger, may exert beneficial therapeutic effects on hypermotility-induced diarrhea because it has the ability to inhibit contractions of colonic smooth muscles." | 3.77 | Intraluminal administration of zingerol, a non-pungent analogue of zingerone, inhibits colonic motility in rats. ( Hirayama, H; Iwami, M; Shiina, T; Shimizu, Y, 2011) |
| "Zingerone is a likely active constituent responsible for the antidiarrheal activity of ginger." | 1.37 | Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats. ( Hirayama, H; Iwami, M; Shiina, T; Shima, T; Shimizu, Y; Takewaki, T, 2011) |
| "3." | 1.29 | Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor. ( Teng, CM; Wu, TS; Yu, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toyoda, M | 2 |
| Ogata, N | 3 |
| Shibata, T | 3 |
| Baba, T | 1 |
| Yamamoto, K | 1 |
| Takase, H | 1 |
| Abe, K | 1 |
| Saito, Y | 1 |
| Suzuki, A | 1 |
| Iwami, M | 2 |
| Shiina, T | 2 |
| Hirayama, H | 2 |
| Shima, T | 1 |
| Takewaki, T | 1 |
| Shimizu, Y | 2 |
| Hernández-Romero, Y | 1 |
| Rojas, JI | 1 |
| Castillo, R | 1 |
| Rojas, A | 1 |
| Mata, R | 1 |
| Matsunaga, K | 1 |
| Shibuya, M | 1 |
| Ohizumi, Y | 1 |
| Yu, SM | 1 |
| Wu, TS | 1 |
| Teng, CM | 1 |
| Carissimi, M | 1 |
| Cattaneo, A | 1 |
| D'Ambrosio, R | 1 |
| Grumelli, E | 1 |
| Milla, E | 1 |
| Ravenna, F | 1 |
10 other studies available for guaiacol and Muscle Contraction
| Article | Year |
|---|---|
Suppression of intestinal smooth muscle contraction by 4-ethylguaiacol, a constituent of wood creosote.
Topics: Animals; Antidiarrheals; Calcium; Calcium Channels; Creosote; Dose-Response Relationship, Drug; Fema | 1993 |
Demonstration of antidiarrheal and antimotility effects of wood creosote.
Topics: Acetylcholine; Animals; Antidiarrheals; Bradykinin; Castor Oil; Creosote; Diarrhea; Electric Stimula | 1993 |
[Pharmacological studies on antidiarrheal effects of a preparation containing berberine and geranii herba].
Topics: Animals; Antidiarrheals; Berberine; Creosote; Drug Combinations; Drugs, Chinese Herbal; Guinea Pigs; | 1993 |
Suppression of intestinal smooth muscle contraction by phenolic compounds.
Topics: Animals; Creosote; Cresols; Dose-Response Relationship, Drug; Electrophysiology; Female; Ileum; In V | 1992 |
Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats.
Topics: Animals; Colon; Gastrointestinal Motility; Guaiacol; In Vitro Techniques; Male; Muscle Contraction; | 2011 |
Intraluminal administration of zingerol, a non-pungent analogue of zingerone, inhibits colonic motility in rats.
Topics: Animals; Colon; Diarrhea; Drug Administration Routes; Gastrointestinal Motility; Guaiacol; Jejunum; | 2011 |
Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.
Topics: Animals; Bibenzyls; Brain; Cattle; Dose-Response Relationship, Drug; Flavonoids; Guaiacol; Guinea Pi | 2004 |
Graminone B, a novel lignan with vasodilative activity from Imperata cylindrica.
Topics: Animals; Drugs, Chinese Herbal; Furans; Guaiacol; In Vitro Techniques; Magnetic Resonance Spectrosco | 1994 |
Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1994 |
Hypotensive quaternary ammonium salts with a guaiacol or thymol residue.
Topics: Animals; Antihypertensive Agents; Cats; Dogs; Electric Stimulation; Guaiacol; Guinea Pigs; Jejunum; | 1968 |