guaiacol has been researched along with Diarrhea in 12 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to compare the efficacy and tolerability of wood creosote with those of loperamide hydrochloride in patients with acute, nonspecific diarrhea." | 9.11 | Multicenter, double-blind, randomized comparison of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, and loperamide in adults with acute nonspecific diarrhea. ( Kuge, T; Shibata, T; Willett, MS, 2004) |
| "The aim of this study was to compare the efficacy and tolerability of wood creosote with those of loperamide hydrochloride in patients with acute, nonspecific diarrhea." | 5.11 | Multicenter, double-blind, randomized comparison of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, and loperamide in adults with acute nonspecific diarrhea. ( Kuge, T; Shibata, T; Willett, MS, 2004) |
| "Zingerone, a pungent component of ginger, may exert beneficial therapeutic effects on hypermotility-induced diarrhea because it has the ability to inhibit contractions of colonic smooth muscles." | 3.77 | Intraluminal administration of zingerol, a non-pungent analogue of zingerone, inhibits colonic motility in rats. ( Hirayama, H; Iwami, M; Shiina, T; Shimizu, Y, 2011) |
| "metoxibutropate) are able to inhibit in-vitro prostaglandin synthesis." | 1.28 | Effects of metoxibutropate, ibuprofen and guaiacol on the gastrointestinal system. ( Bandi, GL; Bozzi, M; Formenti, A; Fossati, A; Passarotti, C; Vimercati, MG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Mizoguchi, M | 1 |
| Takemori, H | 1 |
| Furukawa, S | 1 |
| Ito, M | 2 |
| Asai, M | 1 |
| Morino, H | 1 |
| Miura, T | 1 |
| Yabe, D | 1 |
| Shibata, T | 5 |
| Ataka, K | 3 |
| Kuge, T | 3 |
| Venkova, K | 1 |
| Greenwood-Van Meerveld, B | 1 |
| Willett, MS | 1 |
| Fujino, K | 1 |
| Takahashi, T | 1 |
| Fujimiya, M | 1 |
| Ogata, N | 2 |
| Baba, T | 1 |
| Zhang, J | 1 |
| Wang, S | 1 |
| Li, Y | 1 |
| Xu, P | 1 |
| Chen, F | 1 |
| Tan, Y | 1 |
| Duan, J | 1 |
| Iwami, M | 1 |
| Shiina, T | 1 |
| Hirayama, H | 1 |
| Shimizu, Y | 1 |
| Chen, JC | 1 |
| Huang, LJ | 1 |
| Wu, SL | 1 |
| Kuo, SC | 1 |
| Ho, TY | 1 |
| Hsiang, CY | 1 |
| Soyka, LF | 1 |
| Robinson, DS | 1 |
| Lachant, N | 1 |
| Monaco, J | 1 |
| Fossati, A | 1 |
| Vimercati, MG | 1 |
| Bozzi, M | 1 |
| Passarotti, C | 1 |
| Bandi, GL | 1 |
| Formenti, A | 1 |
1 review available for guaiacol and Diarrhea
| Article | Year |
|---|---|
New views on antidiarrheal effect of wood creosote: is wood creosote really a gastrointestinal antiseptic?
Topics: Animals; Anti-Infective Agents; Antidiarrheals; Calcium; Chlorine; Clinical Trials as Topic; Colon; | 2005 |
1 trial available for guaiacol and Diarrhea
| Article | Year |
|---|---|
Multicenter, double-blind, randomized comparison of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, and loperamide in adults with acute nonspecific diarrhea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidiarrheals; Colic; Creosote; Diarrhea; Double-Blind | 2004 |
10 other studies available for guaiacol and Diarrhea
| Article | Year |
|---|---|
Increased expression of glucagon-like peptide-1 and cystic fibrosis transmembrane conductance regulator in the ileum and colon in mouse treated with metformin.
Topics: Animals; Caco-2 Cells; Colon; Creosote; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regula | 2023 |
Seirogan (wood creosote) inhibits stress-induced ion secretion in rat intestinal epithelium.
Topics: Administration, Oral; Animals; Creosote; Diarrhea; Intestinal Mucosa; Ions; Male; Plant Extracts; Ra | 2003 |
Wood creosote prevents CRF-induced motility via 5-HT3 receptors in proximal and 5-HT4 receptors in distal colon in rats.
Topics: Animals; Colon; Corticotropin-Releasing Hormone; Creosote; Diarrhea; Enteric Nervous System; Excitat | 2007 |
Demonstration of antidiarrheal and antimotility effects of wood creosote.
Topics: Acetylcholine; Animals; Antidiarrheals; Bradykinin; Castor Oil; Creosote; Diarrhea; Electric Stimula | 1993 |
Antidiarrheal activity of wood creosote: inhibition of muscle contraction and enterotoxin-induced fluid secretion in rabbit small intestine.
Topics: Acetylcholine; Animals; Antidiarrheals; Bacterial Proteins; Bacterial Toxins; Barium Compounds; Chlo | 2001 |
Anti-diarrheal constituents of Alpinia oxyphylla.
Topics: Alpinia; Animals; Antidiarrheals; Aquaporin 4; Diarrhea; Duodenum; Flavonoids; Fruit; Guaiacol; Mice | 2013 |
Intraluminal administration of zingerol, a non-pungent analogue of zingerone, inhibits colonic motility in rats.
Topics: Animals; Colon; Diarrhea; Drug Administration Routes; Gastrointestinal Motility; Guaiacol; Jejunum; | 2011 |
Ginger and its bioactive component inhibit enterotoxigenic Escherichia coli heat-labile enterotoxin-induced diarrhea in mice.
Topics: Animals; Bacterial Toxins; Diarrhea; Enterotoxins; Escherichia coli Proteins; Female; G(M1) Ganglios | 2007 |
The misuse of antibiotics for treatment of upper respiratory tract infections in children.
Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Diagnosis, Differential; Diarrhea; Guaiacol; Hum | 1975 |
Effects of metoxibutropate, ibuprofen and guaiacol on the gastrointestinal system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Castor Oil; Diarrhea; Digestive System; Digestive | 1991 |