guaiacol has been researched along with Diabetic Glomerulosclerosis in 3 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment with zingerone markedly abrogated ROS levels, inhibited the NF-кB activation and considerably reduced level of other downstream inflammatory molecules (TNF-α, IL-6, IL-1β), furthermore, zingerone treatment improved renal functioning by significantly decreasing the levels of kidney toxicity markers KIM-1, BUN, creatinine, and LDH and suppressed TGF-β." | 5.51 | Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy. ( Ahmad, B; Ahmad, SB; Bhat, SA; Ganaie, MA; Madkhali, H; Majid, S; Rashid, SM; Rasool, S; Rehman, MU; Shakeel, S, 2019) |
| "The treatment with zingerone markedly abrogated ROS levels, inhibited the NF-кB activation and considerably reduced level of other downstream inflammatory molecules (TNF-α, IL-6, IL-1β), furthermore, zingerone treatment improved renal functioning by significantly decreasing the levels of kidney toxicity markers KIM-1, BUN, creatinine, and LDH and suppressed TGF-β." | 1.51 | Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy. ( Ahmad, B; Ahmad, SB; Bhat, SA; Ganaie, MA; Madkhali, H; Majid, S; Rashid, SM; Rasool, S; Rehman, MU; Shakeel, S, 2019) |
| "Zingerone is a stable active component derived from dry ginger rhizome." | 1.48 | Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4. ( Bao, Y; Cui, Y; Hua, Q; Liu, Y; Shi, Y; Wang, S, 2018) |
| "Gigantol is a bibenzyl compound derived from several medicinal orchids." | 1.48 | Gigantol has Protective Effects against High Glucose-Evoked Nephrotoxicity in Mouse Glomerulus Mesangial Cells by Suppressing ROS/MAPK/NF-κB Signaling Pathways. ( Chen, MF; Hong, TY; Kao, ST; Liou, SS; Liu, IM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, Y | 1 |
| Shi, Y | 1 |
| Bao, Y | 1 |
| Wang, S | 1 |
| Hua, Q | 1 |
| Liu, Y | 1 |
| Rehman, MU | 1 |
| Rashid, SM | 1 |
| Rasool, S | 1 |
| Shakeel, S | 1 |
| Ahmad, B | 1 |
| Ahmad, SB | 1 |
| Madkhali, H | 1 |
| Ganaie, MA | 1 |
| Majid, S | 1 |
| Bhat, SA | 1 |
| Chen, MF | 1 |
| Liou, SS | 1 |
| Hong, TY | 1 |
| Kao, ST | 1 |
| Liu, IM | 1 |
3 other studies available for guaiacol and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4.
Topics: Animals; Cell Death; Collagen Type IV; Diabetic Nephropathies; Down-Regulation; Fibronectins; Glucos | 2018 |
Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Gen | 2019 |
Gigantol has Protective Effects against High Glucose-Evoked Nephrotoxicity in Mouse Glomerulus Mesangial Cells by Suppressing ROS/MAPK/NF-κB Signaling Pathways.
Topics: Animals; Apoptosis; Bibenzyls; Cell Line; Cell Survival; Cells, Cultured; Diabetic Nephropathies; Gl | 2018 |