guaiacol has been researched along with Carcinoma, Hepatocellular in 7 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gigantol is a phenolic compound extracted from Dendrobium." | 5.72 | Effect of gigantol on the proliferation of hepatocellular carcinoma cells tested by a network-based pharmacological approach and experiments. ( Chen, X; Li, H; Li, J; Li, S; Li, X; Xue, X; Yi, Y; Yin, D, 2022) |
| "Gigantol is a phenolic compound extracted from Dendrobium." | 1.72 | Effect of gigantol on the proliferation of hepatocellular carcinoma cells tested by a network-based pharmacological approach and experiments. ( Chen, X; Li, H; Li, J; Li, S; Li, X; Xue, X; Yi, Y; Yin, D, 2022) |
| "Gigantol is a phenolic substance extracted from plants in the genus Dendrobium and used in traditional Chinese medicine." | 1.46 | Gigantol attenuates the proliferation of human liver cancer HepG2 cells through the PI3K/Akt/NF-κB signaling pathway. ( Chen, H; Huang, J; Huang, Y; Lin, L; Wei, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Vogelbein, WK | 1 |
| Fournie, JW | 1 |
| Van Veld, PA | 1 |
| Huggett, RJ | 1 |
| Fang, J | 1 |
| Zhu, H | 1 |
| Xu, P | 1 |
| Jiang, R | 1 |
| Li, S | 1 |
| Li, H | 1 |
| Yin, D | 1 |
| Xue, X | 1 |
| Chen, X | 1 |
| Li, X | 1 |
| Li, J | 1 |
| Yi, Y | 1 |
| Kung, ML | 1 |
| Lin, PY | 1 |
| Huang, ST | 1 |
| Tai, MH | 1 |
| Hsieh, SL | 1 |
| Wu, CC | 1 |
| Yeh, BW | 1 |
| Wu, WJ | 1 |
| Hsieh, S | 1 |
| Chen, H | 1 |
| Huang, Y | 1 |
| Huang, J | 1 |
| Lin, L | 1 |
| Wei, G | 1 |
| Kim, YJ | 1 |
| Jeon, Y | 1 |
| Kim, T | 1 |
| Lim, WC | 1 |
| Ham, J | 1 |
| Park, YN | 1 |
| Kim, TJ | 1 |
| Ko, H | 1 |
| Bakke, OM | 1 |
| Midtvedt, T | 1 |
7 other studies available for guaiacol and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Hepatic neoplasms in the mummichog Fundulus heteroclitus from a creosote-contaminated site.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Creosote; Cresols; Cyprinodontiformes; Fish Diseases; K | 1990 |
Zingerone suppresses proliferation, invasion, and migration of hepatocellular carcinoma cells by the inhibition of MTDH-mediated PI3K/Akt pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Movem | 2022 |
Effect of gigantol on the proliferation of hepatocellular carcinoma cells tested by a network-based pharmacological approach and experiments.
Topics: Bibenzyls; Carcinoma, Hepatocellular; Cell Proliferation; Guaiacol; Humans; Liver Neoplasms; Molecul | 2022 |
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
Topics: Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Line, Tumor; DNA Damage; Guaiacol; Humans; Liv | 2019 |
Gigantol attenuates the proliferation of human liver cancer HepG2 cells through the PI3K/Akt/NF-κB signaling pathway.
Topics: Apoptosis; Bibenzyls; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Flow Cytomet | 2017 |
Combined treatment with zingerone and its novel derivative synergistically inhibits TGF-β1 induced epithelial-mesenchymal transition, migration and invasion of human hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Epithelial-Mesenchymal Transition; Guai | 2017 |
Influence of germ-free status on the excretion of simple phenols of possible significance in tumour promotion.
Topics: Animals; Carcinoma, Hepatocellular; Catechols; Dietary Proteins; Germ-Free Life; Guaiacol; Liver Neo | 1970 |