guaiacol has been researched along with Carcinogenesis in 3 studies
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)." | 7.80 | Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014) |
| "Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA." | 5.51 | Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019) |
| " In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)." | 3.80 | Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014) |
| "Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA." | 1.51 | Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tao, B | 1 |
| Song, Y | 1 |
| Wu, Y | 1 |
| Yang, X | 1 |
| Peng, T | 1 |
| Peng, L | 1 |
| Xia, K | 1 |
| Xia, X | 1 |
| Chen, L | 1 |
| Zhong, C | 1 |
| Ganaie, MA | 1 |
| Al Saeedan, A | 1 |
| Madhkali, H | 1 |
| Jan, BL | 1 |
| Khatlani, T | 1 |
| Sheikh, IA | 1 |
| Rehman, MU | 1 |
| Wani, K | 1 |
| Vinothkumar, R | 2 |
| Sudha, M | 1 |
| Nalini, N | 1 |
3 other studies available for guaiacol and Carcinogenesis
| Article | Year |
|---|---|
Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling.
Topics: AC133 Antigen; Acrylic Resins; Animals; Antineoplastic Agents; Bibenzyls; Brain Neoplasms; Carcinoge | 2021 |
Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Coloni | 2019 |
Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Carcinog | 2014 |