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guaiacol and Cancer of Colon

guaiacol has been researched along with Cancer of Colon in 5 studies

Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)
methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.
guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.

Research Excerpts

ExcerptRelevanceReference
" In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)."7.80Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014)
"Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA."5.51Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019)
" In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)."3.80Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014)
"Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA."1.51Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Su, P1
Veeraraghavan, VP1
Krishna Mohan, S1
Lu, W1
Ganaie, MA1
Al Saeedan, A1
Madhkali, H1
Jan, BL1
Khatlani, T1
Sheikh, IA1
Rehman, MU1
Wani, K1
Greene, LM1
Wang, S1
O'Boyle, NM1
Bright, SA1
Reid, JE1
Kelly, P1
Meegan, MJ1
Zisterer, DM1
Vinothkumar, R2
Sudha, M1
Nalini, N1
Shukla, Y1
Singh, M1

Reviews

1 review available for guaiacol and Cancer of Colon

ArticleYear
Cancer preventive properties of ginger: a brief review.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechols; Colonic Neoplasms; Fatty Alcohols; Ga

2007

Other Studies

4 other studies available for guaiacol and Cancer of Colon

ArticleYear
A ginger derivative, zingerone-a phenolic compound-induces ROS-mediated apoptosis in colon cancer cells (HCT-116).
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:12

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Ce

2019
Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats.
    Environmental toxicology, 2019, Volume: 34, Issue:5

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Coloni

2019
Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer.
    Oncology reports, 2013, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents; Autophagy; Azetidines; Cell Line, Tumor; Cell Survival; Colonic Neop

2013
Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2014, Volume: 23, Issue:5

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Carcinog

2014